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Nama : 1.

Fitri rahayu

2. Wiwin elora Herefa

Kelas : DIV SEMESTER IV B

PERBAIKAN IMUNOLOGI

PARAGRAF 3
Lymphocytes with receptors against endogenous tissue are prematurely
eliminated in the thymus or bone marrow after recognizing their antigen.
This clonal deletion thus results in (central) immunological tolerance.
The immune system learns around the time of birth to distinguish
between foreign and endogenous antigens. Normally it continues to
recognize throughout life those that it came into contact with at this time
as endogenous; all those that come later are recognized as being
foreign. If this distinction fails, autoimmune disease occurs

Limfosit dengan reseptor pada jaringan endogen akan dieliminasi secara


prematur dalam tymus atau tulang susmsum setelah mengenal antigen.
Penghapusan clonal ini dengan demikian menghasilkan toleransi imunologis
(sentral). Sistem kekebalan disetiap waktu kelahirannya akan belajar
membedakan antigen asing dengan antigen endogen. Biasanya disepanjang
hidup mereka akan mengenali semua yang datang sebagai benda asing. Jika
pengenalan itu gagal, penyakit autimun akan terjadi.

SOAL

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