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Journal of Orthopaedics 13 (2016) 431–436

Contents lists available at ScienceDirect

Journal of Orthopaedics
journal homepage: www.elsevier.com/locate/jor

Original Article

Chronic hip dislocations: a rarity. How should we treat them?


V. Selimi a,*, O. Heang b, Y. Kim b, E. Woelber c, J. Gollogly b
a
University of Cambridge, Cambridge, England, United Kingdom
b
Children’s Surgical Centre, Phnom Penh, Cambodia
c
WWAMI (Washington, Alaska, Montana and Idaho), USA

A R T I C L E I N F O A B S T R A C T

Article history: Background: Chronically dislocated hips (>6 weeks) are usually the consequence of difficulties accessing
Received 25 January 2016 appropriate healthcare in a timely fashion after dislocation; this explains why they are more common in
Received in revised form 22 July 2016 developing countries. Due to a lack of research, there is currently no consensus on the best treatment
Accepted 2 September 2016
available for patients presenting with this condition. Therefore, it is important to assess the treatments
Available online 23 September 2016
available so as to ensure that doctors adequately manage those presenting with this debilitating
condition in the future.
Keywords:
Objective: To identify the best treatment strategy for chronic hip dislocations based on the treatment
Chronic
Hip dislocation
outcomes achieved by a free surgical clinic in Phnom Penh, Cambodia.
Patients and method: A retrospective analysis of the surgical centre’s electronic records was conducted.
Patients presenting with hips dislocated for >6 weeks were included whilst congenitally dislocated hips
were excluded. Treatment outcomes, based on follow up notes, were then assessed. Data abstracted
during chart review was analysed using descriptive and comparative statistics.
Results: 72 patients presented to the clinic with chronic hip dislocations. 42 patients received recorded
treatment and 32 were followed up. Among patients with follow-up, 63% experienced ‘good’ outcomes
after treatment. Open reductions, the most common treatment, were successful 65% of the time. The use
of preoperative traction increased the success of open reductions by 13%, however, this result was not
statistically significant (p = 0.64).
Conclusion: Open reductions with pre-operative traction seem to be an acceptable treatment in this
setting.
ß 2016 Published by Elsevier, a division of RELX India, Pvt. Ltd on behalf of Prof. PK Surendran Memorial
Education Foundation.

1. Introduction Chronically dislocated hips (>6 weeks) are a rarity in many


regions of the world where there is rapid access to healthcare; this
Dislocated hips are treated as emergencies in developed has resulted in scarcity of recent scholarship assessing the
countries. When reduction of the hip is delayed, the femoral head treatments available for this condition. As chronically dislocated
migrates proximally, causing a leg length discrepancy while hips are more common in Cambodia, the aim of this study was to
compromising vascular supply from the foveolar artery and the assess which treatment approaches provided at a free NGO clinic in
anastomosis of vessels from the femoral circumflex arteries. Phnom Penh, Cambodia, have yielded the best outcomes for
Possible complications stemming from the delay of treatment patients, in order to help guide the future practice of doctors who
include avascular necrosis of the femoral head, degenerative do encounter this problem.
arthritis, ankylosis, and sciatic nerve injury.1–4 It has been shown
that earlier reductions are associated with better clinical results.5,6 2. Materials and methods

2.1. Case identification (data abstraction)


* Corresponding author at: Children’s Surgical Centre, Kien Khleang National
Rehabilitation Center, Khan Ruseykeo, Sangkat Chroy Changvar, Phnom Penh,
The surgical centre’s Electronic Medical Record (EMR) system,
Cambodia. which includes records from 2008, was used to conduct a
E-mail address: vs342@cam.ac.uk (V. Selimi). retrospective analysis of patients that had presented to the clinic

http://dx.doi.org/10.1016/j.jor.2016.09.002
0972-978X/ß 2016 Published by Elsevier, a division of RELX India, Pvt. Ltd on behalf of Prof. PK Surendran Memorial Education Foundation.
432 V. Selimi et al. / Journal of Orthopaedics 13 (2016) 431–436

with chronic hip dislocations. Because English is not the first A Welch two-sample t-test was used to determine whether the
language of many of the surgeons, a variety of search terms were delay between dislocation and presentation differed significantly
used to cover potentially misspelled diagnoses for ‘hip dislocation’ between patients with and without preoperative traction, both for
when searching for patients. all surgeries and for the restricted subgroup of patients treated
EMR patient histories were reviewed and only patients with open reduction. Next, Fisher’s exact test was used to
presenting with dislocations >6 weeks old were included in the determine differences in the number of good outcomes between
study. This interval is greater than that used by Garrett (>72 h) in patients with and without traction prior to open reduction.
another paper considering chronically dislocated hips, however, no Statistical significance for all tests was defined at p < 0.05. All
consistent standard exists for defining chronicity.7,8 Additionally, statistical analysis was performed using R version 3.1.1.
congenital hip dislocations were excluded.
The records of patients included in the study were then 3. Results
examined and the following data abstracted: patient demo-
graphics, injury aetiology, the time delay between dislocation 72 patients presented to the clinic with chronic hip dislocations.
and presentation, preoperative treatment approach (traction vs. The average age of these patients was 27 and a statistically
none), operative treatment approach, and follow up notes. significant majority (71%, p = 0.02) were males. The major causes of
these dislocations were falls (36 cases) and motor vehicle accidents
2.2. Data analysis (MVA) (17 cases).
Of the 72 patients that presented, 42 proceeded to have
Statistical analysis consisted of descriptive statistics for treatment at the hospital. The average delay from dislocation to
demographic characteristics, aetiology, delay between dislocation presentation for these patients was 18 months (range 6 weeks to
and presentation to clinic and treatment outcomes (patients were 13 years). Ten of the patients receiving treatment were not
divided into subgroups based on the type of treatment they followed up. For the 32 patients that remained, the average time
received for the last two). from treatment (operation) to the last follow-up was 11 months
Fisher’s exact test was used to assess whether there was a (range 20 days to 39 months). Five of the 10 patients lost to follow-
difference in the sex ratio of treated patients. up had good postoperative outcomes noted in their records before
A one-way analysis of variance (ANOVA) was used to detect discharge.
whether the delay between dislocation and presentation to the A variety of operations were used to treat the dislocated hips
clinic differed significantly between patients who received presenting to the clinic. Closed reductions were predominantly
different treatments at the centre; closed reduction, open used for patients presenting with hips which had been dislocated
reduction, arthrodesis or total hip replacement (THR) were for a short period of time (mean = 1.9 months) (Table 1); open
analysed. Each of these treatments had been used to treat three reductions were used to treat hips which had been dislocated for a
or more patients included in the study; this frequency of use mean of 7.5 months longer than those for which closed reductions
enabled them to be selected for analysis. Post hoc ANOVA analysis were used. Total Hip Replacement (THR) was only attempted as a
was performed using Tukey’s honest significance test and Bartlett’s first line treatment for hips that had been dislocated for longer
test of homogeneity of variance. periods (mean = 10 years). The delay before surgeons opted for
Operation outcomes, based on follow-up notes and radiograph- THR was statistically significant when compared to open reduc-
ic evidence discovered during chart review in EMR, were used to tion, closed reduction, and arthrodesis using ANOVA and Tukey’s
compare the success of the varying treatments. range test (p < 0.0001). Bartlett’s test of homogeneity of variance
Data abstracted during chart review was insufficient to reliably showed that the subgroup samples were non-normally distributed
stratify according to Epstein criteria, Garrett criteria, or Oxford Hip (K2 = 48, df = 3, p < 0.0001). When Welch’s t test was used to
Score7,9,10 which the few other papers examining chronic hip compare the delay to treatment between open and closed
dislocations have used to assess treatment outcomes. Both the reductions, closed reduction was associated with shorter delays
Garrett and Epstein criteria used non-interval, ordinal grades.7 Like ( 0.64 to 14.48, 95% CI, p = 0.03).
these scoring systems, we decided to use categorical measures to Fig. 1 highlights the outcomes of the different operations used
simplify outcome analysis; operative outcomes were divided into to treat the dislocated hips. The most common operations were
‘bad’ and ‘good’ grades. open reductions (n = 24) and closed reductions (n = 7). If only
A ‘bad’ outcome was defined by presence of one or more of the patients for which there is follow-up data are considered, 63% of all
following postoperatively: need for a revision operation, postop- chronic hip dislocations treated had good outcomes and open
erative dislocation, a limited range of movement (ROM) significant
enough to affect daily life (work/household activities), positive Table 1
Trendelenburg sign or postoperative necrosis of the femur. Pain, a Table showing the delay between hip dislocation and presentation to clinic for
limited ROM not affecting daily living and long-term use of patients receiving various forms of treatment. (Delay to presentation data for two of
the seven patients treated with closed reductions could not be found in the medical
crutches were not considered bad outcomes. While these are not
records).
considered good outcomes in more developed countries where
acute dislocations are treated promptly, we accepted that the Treatment Number Delay between
(operation) of patients dislocation and
chronicity of the presenting complaint prevents the same
presentation (months)
postoperative outcomes being achieved in patients in developing
countries. ‘Good’ outcomes were defined by the absence of follow Mean Range

up complications that made an outcome bad (described above). Closed reduction 7 1.9 1.5–2
The frequency of good and bad outcomes for the different Open reduction 24 9.4 1.5–72
Arthrodesis 4 10 5–14
treatments used was then compared.
THR 3 120 48–156
Descriptive statistics were also used to analyse pre-operative Hemiarthroplasty 1 11 11
treatment; the number of days patients spent in traction (patients Osteotomy 1 60 60
were again divided into groups based on the treatment they went Arthroplasty 1 11 11
on to receive) and the weights used at the beginning and end of Bone graft 1 3 3
Overall 42 18 1.5–156
traction were examined.
V. Selimi et al. / Journal of Orthopaedics 13 (2016) 431–436 433

Success of the varying treatments used for chronic hip dislocations


12 11

Number of patients
10
8 7
6
6
4 3 3 3 Good Result
22
2 1 1 1 1 1 Bad Result
0 00 00 0 0 00 00
0 No post-op Follow up

Treatment (Operation)

Fig. 1. Bar chart depicting the outcomes of varying treatments for chronic hip dislocations used.

reductions, the most common treatment, had good outcomes after bad results, and no follow-up by treatment subgroup are also
65% of procedures. Because operations other than open reductions presented in Table 2.
were performed less often, statistical comparisons of outcomes by Preoperative traction vs. no traction was compared in the open
procedure type could not be performed. reduction group only (this was the only group large enough to
Some patients received skeletal traction to manoeuvre the head divide into two pre-operative sub groups). Seven of ten (70%) with
of the femur into the acetabulum before operative treatment. On traction had good results whilst 4/7 (57%) of those without traction
average, patients who had, had traction received it for 9.9 (range 1– had good results—a difference of 13% (Fig. 2). Using Fisher’s exact
15) days before operative treatment; on average, a start weight of test, traction in this group was associated with more good
11.0 kg (range 1–20 kg) was utilised and increased to 13.7 kg outcomes (OR = 1.69, 0.15–20.06, 95% CI), but this result was
(range 2–30 kg) just before treatment. Patients receiving traction not statistically significant (p = 0.6437). Importantly, preoperative
preoperatively had hips that had been dislocated for an average of patient characteristics differed significantly between those with
one month longer (25 patients; delay to presentation average: traction and those without. The traction group had dislocations
19 months, range: 6 weeks–5 years) than those who did not receive that had been present for nearly 12 months longer (15 vs.
traction (17 patients; delay to presentation average: 18 months, 3.23 months). Although the sample sizes were small, this
range: 6 weeks–13 years) when the type of operation was not difference approached statistical significance using Welch’s t-test
considered. This difference was not statistically significant (p = 0.11). Presumably, surgeons thought the pull of the muscles
(p = 0.93). However, when the individual type of operation was would not be strong in dislocations that were more recent, and
considered e.g. open reduction, use of traction tended to be surgeons would therefore be able to generate enough force to pull
associated with hips that had been dislocated for longer periods. the head of the femur into the acetabulum during surgery. Of the
The number of patients in each treatment category and the 4 patients with no traction who had good results, 2 had operations
time elapsed between dislocation and presentations are pre- one day after presenting to the surgical centre and the average time
sented in Table 2. This highlights the time elapsed between between presentation and operation was 2.75 days. It is therefore
dislocation and presentation tended to be higher in the subgroups unlikely that these patients had traction that was not documented
treated with traction. The number of patients with good results, by EMR in such short intervals.

Table 2
Table highlighting the delay between dislocation and presentation for patients with chronically dislocated hips; operations are subdivided to indicate whether or not a group
of patients received pre-operative traction or not. The operative outcomes of each sub group are also noted. (Delay to presentation data for two of the seven patients treated
with closed reductions could not be found in the medical records).

Operation Number Delay between dislocation Number of patients with a given result
of patients and presentation (months)

Mean Range Good Bad No follow up

Closed reduction (no traction) 7 1.9 1.5–2 2 2 3


Closed reduction (traction) – – – – – –
Open reduction (no traction) 12 3.2 2–11.5 4 3 5
Open reduction (traction) 12 15 1.5–7.2 7 3 2
Arthrodesis (no traction) 3 8.7 5–11 – 3 –
Arthrodesis (traction) 1 14 14 1 – –
THR (no traction) 2 156 156 2 – –
THR (traction) 1 48 48 1 – –
Hemiarthroplasty (no traction) – – – – – –
Hemiarthroplasty (traction) 1 11 11 1 – –
Osteotomy (no traction) – – – – – –
Osteotomy (traction) 1 60 60 – 1 –
Arthroplasty (no traction) 1 11 11 1 – –
Arthroplasty (traction) – – – – – –
Bone graft (no traction) – – – – – –
Bone graft (traction) 1 3 3 1 – –
434 V. Selimi et al. / Journal of Orthopaedics 13 (2016) 431–436

The effect of pre-op


perative tracction for thee open
redduction of chronic
c hip ddislocationss
8 7

Number of patients
7
6 5
5 4
4 3 3
3 2
2
1 Traction
0 Tractioon
Good Result
R Bad Resuult N
No follow up
Trreatment Ou
utcome

Fig. 2. Bar chart reflecting the outcomes of chronic hip dislocations treated with open reductions based on whether or not pre-operative traction was utilised.

Fig. 3 exhibits pelvic radiographs of a patient’s chronically 39 traumatic hip dislocations that had remained unreduced for
dislocated hip on presentation; post-traction, with movement of over 72 h found that THR may be associated with more ‘good’
the femoral head into the acetabulum (preoperatively) and a good outcomes (10 of 13 hips) compared to closed or open reduction
outcome, post-open reduction, upon follow up. (3 of 20) and hips left dislocated (0 of 6).7 In our study, all 3 (100%)
of hips treated by THR had good outcomes, despite these patients
4. Discussion presenting after significant treatment delay (mean = 120 months).
However, due to the low number of patients treated with THR
4.1. Treatment options (n = 3), it was not possible to compare the results of THR to open
reduction.
In the developing world, treatment of dislocated hips is often Prostheses were not very commonly used at the centre; this is
delayed. In Cambodia, a marked delay in presentation is frequently partially due to cost and the technique the centre uses to decide
due to the use of Khmer Traditional Medicine (KTM) prior to whether or not one is necessary. Intraoperatively, when the
seeking western medical advice. A previous study of chronic hip femoral heads were exposed at operation, they were drilled with a
dislocations in Cambodia found that 82% of 33 patients presented 3.5 mm bit and observed for bleeding. A majority of the heads bled
to a clinic providing KTM prior to seeking Western medical on drilling (Fig. 4) and were deemed vascularised so fit to be
treatment.11 Other barriers to care include lack of knowledge of reduced if possible. If they did not bleed, avascular necrosis was
free NGO medical services such as this clinic, the price diagnosed, and the femoral head was replaced with a prosthesis.
transportation to access treatment, and the opportunity cost Sometimes, the femoral head bled but was soft and indented while
associated with time away from employment. trying to reduce it, producing a ‘‘ping-pong sign’’. In such cases, a
Therefore, this study aimed to help guide the treatment of those prosthesis was also used. Acetabular replacement was only carried
presenting with chronically dislocated hips in developing coun- out if the acetabulum was damaged, but capable of being
tries. By examining the follow-up data of patients presenting with reconstructed with a prosthesis; otherwise, if the acetabulum
dislocations >6 weeks old, we were able to identify the outcomes was severely deformed, hip arthrodesis was performed or a
of varying treatments for chronic hip dislocations performed at the Girdlestone arthroplasty was done.
centre. Among the 32 patients with follow-up data, 63% had good Drilling the femoral head was used to identify avascular
outcomes. It is, however, difficult to compare the success of these necrosis; bleeding obviously indicated that the head had a blood
operations to those considered in other studies because so few supply. However, it is perfectly possible that in the majority of
studies have documented surgical outcomes in hips that have cases, avascular necrosis of the head might have taken place when
remained unreduced for more than 6 weeks. the dislocation was experienced; since such a long time had
Historically, open reduction has been a more common approach elapsed after injury in the majority of cases, ‘‘creeping substitu-
in the developing world and is associated with acceptable tion’’ had revascularised the head.12 Similarly, inadvertent
outcomes. A 1999 study based on 12 late unreduced traumatic indentation of the head during reduction indicated osteoporosis,
posterior hip dislocations in children in hospitals in India and but whether this was due to ‘‘creeping substitution’’12 or to ‘‘disuse
Malaysia reported 11 excellent outcomes using a standard lateral osteoporosis’’13 was impossible to determine.
open reduction after insufficient reduction with traction alone.3 Postoperatively, to maintain reductions, spica cast were used
Other contemporary surgeons have reported similar success with for 6 weeks at the centre.
open reductions.3 There were a variety of complications that led to 12 patients
Our study showed that open reductions, used most commonly having ‘bad’ outcomes. The two that received closed reductions as
to treat chronically dislocated hips at the centre, were successful an initial treatment were classed as ‘bad’ as reductions were not
65% of the time. It is, however, challenging to compare the achievable with this initial treatment and, open reductions had to
efficacy of this treatment to that of other operations for two be used. The 6 ‘bad’ open reductions had a variety of complications;
reasons: (1) closed reductions were predominantly attempted on post-operative dislocation (1 patient), subluxation (1 patient),
hips which had not been dislocated for as long as open impaired ROM (2 patients), substantial pain (1 patient), Trende-
reductions, and (2) other operations were not used frequently lenberg +ve (1 patient). Two patients went on to have recorded
enough to obtain a large enough sample to make statistical revision operations; one due to subluxation and the other due to
comparison possible. the surgeons not being able to reduce the hip intra-operatively (no
Similar to our study, previous scholarship has suffered from pre-operative traction had been used). The three arthrodesis that
small sample sizes due to the relative rarity of a presenting hip were ‘bad’ had all failed to fuse. The ‘bad’ osteotomy was
with significant treatment delay. One study in the United States of complicated with partial necrosis of the femur.
V. Selimi et al. / Journal of Orthopaedics 13 (2016) 431–436 435

Fig. 4. Drilling of femoral head produces bleeding.

4.2. Pre-operative treatment

Whilst it has been shown that traction before open reduction


seems to improve postoperative outcomes (70% with traction vs.
57% without), our results were not statistically significant
(p = 0.6437) due to the small number of patients in this study.
Furthermore, there is a paucity of follow-up data for a relatively
large number (n = 5, 42%) of patients in the ‘no traction’ treatment
group. If these patients had bad outcomes, it would add more
validity to the use of preoperative traction. However, it is also
possible that lack of follow-up indicated a successful operation,
and that more aggressive surveillance of patients would further
prevent rejection of the null hypothesis. More concerning,
statistically, is the difference in patient characteristics between
patients treated with and without traction. The subgroup with
traction presented with hips that had been dislocated for a longer
mean period (15 vs. 3.23 months, p = 0.11), which may have
predisposed them to worse outcomes due to vascular compromise,
degenerative arthritis, or sciatic nerve injury. Due to these
differences, our results remain equivocal.

4.3. Difficulties with follow-up data

The manner in which follow-up data was recorded in the clinic


EMR was not consistent. For example, in several instances, the
postoperative state of the hip and ROM were not documented. In
such cases, the progress was usually noted as ‘good,’ so it was
assumed that the patient had a good outcome that did not require
further discussion. Omission of potentially relevant outcome data
makes it possible that our results inflate the success of operations.
Furthermore, comparing the success of operations was
complicated by low rates of follow-up and small sample sizes in
treatment subgroups. To power the study and provide greater
validity, a larger sample size, over a greater period of time must be
studied. However, due to the relative rarity of chronically
dislocated hips, it is important to publish surgical outcomes even
when population sizes are insufficiently large to power compara-
tive analysis. Few single clinics in the developing world are likely
treat enough chronically dislocated hips to achieve appropriate
Fig. 3. Top: Pelvic radiograph of a chronically dislocated hip at presentation, three statistical power for comparisons across a range of treatment
months after the causative fall. Middle: Pelvic radiograph two days after strategies.
presentation. Skeletal traction with 10 kg was used. An open reduction was
Future prospective analysis of patients presenting with chronic
preformed seven days after this. Bottom: Radiograph preformed on follow up. This
patient had a good outcome. hip dislocations may provide a more accurate reflection of a
patient’s journey at the clinic as it would rely less on retrospective
inspection of patient records that do not always contain sufficient
data to make a clear diagnosis or an assessment of outcome quality.
436 V. Selimi et al. / Journal of Orthopaedics 13 (2016) 431–436

Moreover, it is also important to consider that the time point of the it, alongside that of others, can help guide the future treatment of a
last follow up from operation varied between patients; the patients condition which is debilitating for so many in the developing
are therefore at different time points in recovery, potentially world.
affecting outcome data. A given follow-up period may therefore be
set in the future to allow for a more accurate comparison of Conflicts of interest
outcomes.
Another issue was also the loss of patients to follow up; this is The authors have none to declare.
common in free or low-cost surgical clinics in Cambodia and the
developing world. In the present study, 76% (32/42) of patients References
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