Oral abstracts / Annals of Physical and Rehabilitation Medicine 61S (2018) e1–e102
Keywords Total knee arthroplasty; Forgetten Joint Score; Rasch
analysis
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
https://doi.org/10.1016/j.rehab.2018.05.015
ISPR8-0526
Knee osteoarthitis and platelet-rich
plasma treatment: How to improve
the efficiency?
C. Milants 1 , O. Bruyère 2 , J.F. Kaux 3,∗
1 Liège, Belgium
2 University of Liège, Epidemiology, Liège, Belgium
3 University of Liege, Physical and Rehabiitation Medicine & Sports
Traumatology, Liège, Belgium
∗ Corresponding author.
E-mail address: jfkaux@chuliege.be (J.F. Kaux)
Introduction/Background The management of chondral disease
is challenging. New studies have focused on modern therapeutic
methods that stimulate cartilage healing process and improve the
damage, including the use of platelet-rich plasma (PRP). PRP is pre-
pared from autologous blood by centrifugation to obtain a highly
concentrated sample of platelets. Due to the mixed results from
controlled studies, the clinical efficacy of PRP in the treatment of
knee OA is unclear with shortcomings in the current literature.
Material and method A comparison of the outcomes of random-
ized controlled trials (RCTs) included in the 3 most recent and
high-quality meta-analyses to classify the different studies in 2
groups (bad responders group (BRG) and very good responders
group (VGRG)). The minimal clinically important improvement
(MCII) was defined to help determining whether an observed dif-
ference is clinically important. We used MCII values to classify
the different studies in 2 groups depending on the outcomes:
BRG < MCII and VGRG > 2xMCII.
Results From the 19 RCTs analyzed, 7 trials were included in the
VGRG and 4 in the BRG. In VGRG, 1 or 2 injections were performed
in 4/7 trials, time between injections was 2 to 3 weeks in 4/5 studies
with many injections, volume injected varied from 2.5 to 8 mL, and
single spinning technique was used in 5/7 studies. PRP classification
was Mishra 4B and PAWP2B␤ in 5/7 studies. The use of PRP with
leukocytes is only found in the BRG.
Conclusion Our study helped identify features of PRP recom-
mended for knee OA treatment, such as the use of a single spinning
technique, a platelet concentration lower than 5 times the baseline
(from 3 to 4), and avoiding leukocytes and erythrocytes. We rec-
ommend leveraging this information about PRP for future studies.
Keywords PRP; Osteoarthritis; Platelet-rich plasma
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
https://doi.org/10.1016/j.rehab.2018.05.016
ISPR8-0120
Study of effectiveness of lateral wedge
insole in medial compartment of
osteoarthritis of knee treated with
viscosupplementation
V. Kanaujia
AIIMS, Physical Medicine & Rehabilitation, Rishikesh, India
E-mail address: vinay.kanaujia87@gmail.com
Introduction/Background Osteoarthritis (OA) of knee is one of
most common musculoskeletal disorder affecting the elderly
population in Asia-Pacific region. The goals of OA treatment
include alleviation of pain and improvement of functional status.
Viscosupplementation (VS) is being a more widely accepted and
practiced mode of treatment for symptomatic osteoarthritis of
e7
knee. In addition to this heat and cold therapy, exercise, electro
therapy, ADL modification, orthotic devices like Lateral Wedge
Insole (LWI), shock absorbing insoles and knee brace are also
available and widely prescribed in day-to-day practice.
Material and method This study is a single center randomized
interventional study in which total 60 patients were selected from
tertiary care center and divided in two equal groups using com-
puterized block randomization. Group A got only VS while Group B
got VS and LWI. Assessment was done at baseline and then after 2,
4 and 12 weeks after the intervention by using VAS, WOMAC and
HAQ.
Results In this study all the patients in both group showed sta-
tistically significant improvement in VAS, WOMAC and HAQ on all
three follow-ups over the previous assessment (P-value < .0005).
On inter-group comparison, statistically significant better results
were noticed in the WOMAC scores of group B at 2 and4 week (P-
value < .0005) follow up over group A. Similar benefit or difference
was not evident in terms of VAS or HAQ (P-value > .0005) at any
follow up in any of the two groups. The statistically better result in
group B on WOMAC was not seen at the 12-week follow-up.
Conclusion Bimodal approach of VS and LWI with different mech-
anism of action has a definite benefit in the management of OA
knee. Lateral wedge on combination with VS results in faster onset
of benefit within 2 weeks in function as tested by WOMAC scale.
OA knee equalized by 12 week of follow-up.
Keywords Knee osteoarthritis; Viscosupplimentation; Lateral
wedge insole
Disclosure of interest The author has not supplied his declaration
of competing interest.
https://doi.org/10.1016/j.rehab.2018.05.017
ISPR8-1603
Minimally invasive surgery leads to
earlier recovery of quality of gait after
total hip arthroplasty secondary
analysis of a randomized controlled
trial
D. Lussato 1 , D. Biau 2 , M.M. Lefevre-Colau 3 , F. Rannou 4 ,
P. Anract 2 , A. Roren 5,∗
1 Hôpital Cochin, AP–HP, rééducation et réadaptation de l’appareil
locomoteur et des pathologies du rachis, Paris, France
2 Hôpital Cochin, AP–HP, université Paris-Descartes, équipe ECaMO
CRESS-UMR1153, chirurgie orthopédique, Paris, France
3 Hôpital Cochin, AP–HP, université Paris-Descartes, équipe ECaMO
CRESS-UMR1153, institut fédératif de recherche sur le handicap,
rééducation et réadaptation de l’appareil locomoteur et des
pathologies du rachis, Paris, France
4 Hôpital Cochin, AP–HP, université Paris-Descartes, Inserm U1124,
rééducation et réadaptation de l’appareil locomoteur et des
pathologies du rachis, Paris, France
5 Hôpital Cochin, AP–HP, équipe ECaMO CRESS-UMR1153, institut
fédératif de recherche sur le handicap, rééducation et réadaptation de
l’appareil locomoteur et des pathologies du rachis, Paris, France
∗ Corresponding author.
E-mail address: alexandraroren@yahoo.fr (A. Roren)
Introduction/Background Recently, minimally invasive hip
surgery (MHS) has been developed as a mean of accelerating
patient’s time to full recovery. Previous analysis of early postop-
erative data showed that the time to reach complete functional
independence (including walking 30 meters) wasn’t shortened
with MHS compared to standard hip surgery (SHS). However there
is only little evidence on the benefits of MHS on the quality of gait.
Symmetrical distribution of load is a useful clinical tool related to
it.
The aim of this secondary analysis was then to compare the quality
of gait in patients with MHS or SHS.