Sophisticated screening Advanced biotechnology

for skin and hair

services for the beauty and

health industry
SCoutech is a highly specialized biotechnology joint venture
­focusing on skin and hair. We offer screening services for cosmetic
raw materials (both skin and hair), cosmetic ­formulations (skin),
nutraceuticals and pharmaceuticals. We support our customers
by researching both the efficacy­and the mode of action of new
potential products.

We use cell- and tissue-based screening assays to support the

development of effective products for skin and hair care.

With all the models we use, including our groundbreaking patented

PSOCM (Pig Skin Organ Culture Model), we provide both reliable
and ethical test procedures. Our screening services are in full
compliance with the EC directive which bans animal testing on
personal care products.

Contact:
Fields of activity SCoutech
c/o Cutech srl
• Personal care industry via Uruguay 53
In vitro and ex vivo efficacy testing I-35127 Padova
Italy
• Nutraceuticals industry
Claim support Phone/Fax: +39 049 762 8532

• Pharmaceuticals industry e-mail: info@scoutech.it

Preclinical research www.scoutech.it
SCoutech is a joint venture of Cutech and Symrise.
Cutech is a biotech company that focuses on designing highly informative screening tools as an
alternative to animal testing. Symrise has wide experience in developing and producing innovative
raw materials and compositions for the personal care, food and pharmaceutical industries. The Screening Services
skills of these companies have merged in a joint venture that aims to provide their customers with
solutions which verify both the efficacy and the mechanism of action of their products. for Hair and Skin
Experience, competence Our services Our models
and consulting all in one
Hair Microdissected human hair follicles Applications:
SCoutech is a research-driven biotechnology joint venture Growth Stress • Anagen VI phase hair follicle organ culture • Growth
which offers exclusive screening assays and models. • Hair follicle elongation • Proliferation and apoptosis • Organ culture until day 10 • Pigmentation
• Hair cycle staging • Hair cycle staging • Pigmented and unpigmented hair follicles • Stress
We combine biotechnological expertise with a profound • Vitality • Inter-individual variability can be tested • Shaft quality
knowledge of the markets for personal care, cosmetics, Pigmentation • Antioxidant potential
nutraceuticals and pharmaceuticals as well as their • Melanin detection/quantification
respective raw materials. It is our synergistic competence • Melanocyte detection/quantification Hair shaft Full-thickness human skin ex vivo Applications:
which results in better services for our clients: We • Melanotic melanocyte detection/quantification • Quality
understand the needs of our customers as well as what • Tyrosinase expression quantification • Ex vivo skin culture until day 10 • Structure analysis
consumers want. • Skin excised from different body areas • Pigmentation
• Weekly availability • Aging/photoaging
We do not consider screening to be a mechanical activity • Inter-individual variability can be tested • Stress/apoptosis
done by equipment. Instead, our experts’ purpose is to • Irritation/sensitization
offer you consulting throughout every phase of the entire Skin
development process so we can resolve your specific
challenges in the area of skin and hair. Pigmentation Stress/apoptosis Full-thickness pig skin ex vivo (PSOCM) Applications:
• Melanin detection/quantification • Proliferation/apoptosis
• Melanocytes detection/quantification • Toxicity • Ex vivo pig skin (unpigmented/pigmented skin)* • Hair pigmentation
• Tyrosinase activity • Antioxidant potential • Functional skin for up to 21 days (long term experiments) • Hair growth
• High predictability for human skin in vivo • Skin morphology
Structure (growth/differentiation) Aging/photoaging • Better reproducibility compared to ex vivo human skin • Skin aging
• Morphology • Tissue structure • Ethical • Skin pigmentation
• Keratinocytes differentiation • Sunburn cell quantification • Versatile • UV protection
• Collagen stimulation/inhibition • Antioxidant potential • In full compliance with European cosmetic legislation • Skin sensitization°
• Skin irritation°
Irritation/sensitization • Fat management
• Vitality
• RNA degradation
• Topical immuno-response
• Inflammation Cell cultures
Primary cells from human skin Co-cultures of primary cells
Fibroblasts, Keratinocytes Fibroblasts/Keratinocytes
Subcutis (Melanocytes) (Keratinocytes/Melanocytes)

Fat management Primary cells from hair follicles Cell lines

* Skin derived from animals
• Catabolism (lypolysis) Fibroblasts, Keratinocytes Fibroblasts, Keratinocytes, slaughtered for meat
• Glucose metabolism (Melanocytes) Melanocytes ° Development in progress
Experience, competence Our services Our models
and consulting all in one
Hair Microdissected human hair follicles Applications:
SCoutech is a research-driven biotechnology joint venture Growth Stress • Anagen VI phase hair follicle organ culture • Growth
which offers exclusive screening assays and models. • Hair follicle elongation • Proliferation and apoptosis • Organ culture until day 10 • Pigmentation
• Hair cycle staging • Hair cycle staging • Pigmented and unpigmented hair follicles • Stress
We combine biotechnological expertise with a profound • Vitality • Inter-individual variability can be tested • Shaft quality
knowledge of the markets for personal care, cosmetics, Pigmentation • Antioxidant potential
nutraceuticals and pharmaceuticals as well as their • Melanin detection/quantification
respective raw materials. It is our synergistic competence • Melanocyte detection/quantification Hair shaft Full-thickness human skin ex vivo Applications:
which results in better services for our clients: We • Melanotic melanocyte detection/quantification • Quality
understand the needs of our customers as well as what • Tyrosinase expression quantification • Ex vivo skin culture until day 10 • Structure analysis
consumers want. • Skin excised from different body areas • Pigmentation
• Weekly availability • Aging/photoaging
We do not consider screening to be a mechanical activity • Inter-individual variability can be tested • Stress/apoptosis
done by equipment. Instead, our experts’ purpose is to • Irritation/sensitization
offer you consulting throughout every phase of the entire Skin
development process so we can resolve your specific
challenges in the area of skin and hair. Pigmentation Stress/apoptosis Full-thickness pig skin ex vivo (PSOCM) Applications:
• Melanin detection/quantification • Proliferation/apoptosis
• Melanocytes detection/quantification • Toxicity • Ex vivo pig skin (unpigmented/pigmented skin)* • Hair pigmentation
• Tyrosinase activity • Antioxidant potential • Functional skin for up to 21 days (long term experiments) • Hair growth
• High predictability for human skin in vivo • Skin morphology
Structure (growth/differentiation) Aging/photoaging • Better reproducibility compared to ex vivo human skin • Skin aging
• Morphology • Tissue structure • Ethical • Skin pigmentation
• Keratinocytes differentiation • Sunburn cell quantification • Versatile • UV protection
• Collagen stimulation/inhibition • Antioxidant potential • In full compliance with European cosmetic legislation • Skin sensitization°
• Skin irritation°
Irritation/sensitization • Fat management
• Vitality
• RNA degradation
• Topical immuno-response
• Inflammation Cell cultures
Primary cells from human skin Co-cultures of primary cells
Fibroblasts, Keratinocytes Fibroblasts/Keratinocytes
Subcutis (Melanocytes) (Keratinocytes/Melanocytes)

Fat management Primary cells from hair follicles Cell lines

* Skin derived from animals
• Catabolism (lypolysis) Fibroblasts, Keratinocytes Fibroblasts, Keratinocytes, slaughtered for meat
• Glucose metabolism (Melanocytes) Melanocytes ° Development in progress
Experience, competence Our services Our models
and consulting all in one
Hair Microdissected human hair follicles Applications:
SCoutech is a research-driven biotechnology joint venture Growth Stress • Anagen VI phase hair follicle organ culture • Growth
which offers exclusive screening assays and models. • Hair follicle elongation • Proliferation and apoptosis • Organ culture until day 10 • Pigmentation
• Hair cycle staging • Hair cycle staging • Pigmented and unpigmented hair follicles • Stress
We combine biotechnological expertise with a profound • Vitality • Inter-individual variability can be tested • Shaft quality
knowledge of the markets for personal care, cosmetics, Pigmentation • Antioxidant potential
nutraceuticals and pharmaceuticals as well as their • Melanin detection/quantification
respective raw materials. It is our synergistic competence • Melanocyte detection/quantification Hair shaft Full-thickness human skin ex vivo Applications:
which results in better services for our clients: We • Melanotic melanocyte detection/quantification • Quality
understand the needs of our customers as well as what • Tyrosinase expression quantification • Ex vivo skin culture until day 10 • Structure analysis
consumers want. • Skin excised from different body areas • Pigmentation
• Weekly availability • Aging/photoaging
We do not consider screening to be a mechanical activity • Inter-individual variability can be tested • Stress/apoptosis
done by equipment. Instead, our experts’ purpose is to • Irritation/sensitization
offer you consulting throughout every phase of the entire Skin
development process so we can resolve your specific
challenges in the area of skin and hair. Pigmentation Stress/apoptosis Full-thickness pig skin ex vivo (PSOCM) Applications:
• Melanin detection/quantification • Proliferation/apoptosis
• Melanocytes detection/quantification • Toxicity • Ex vivo pig skin (unpigmented/pigmented skin)* • Hair pigmentation
• Tyrosinase activity • Antioxidant potential • Functional skin for up to 21 days (long term experiments) • Hair growth
• High predictability for human skin in vivo • Skin morphology
Structure (growth/differentiation) Aging/photoaging • Better reproducibility compared to ex vivo human skin • Skin aging
• Morphology • Tissue structure • Ethical • Skin pigmentation
• Keratinocytes differentiation • Sunburn cell quantification • Versatile • UV protection
• Collagen stimulation/inhibition • Antioxidant potential • In full compliance with European cosmetic legislation • Skin sensitization°
• Skin irritation°
Irritation/sensitization • Fat management
• Vitality
• RNA degradation
• Topical immuno-response
• Inflammation Cell cultures
Primary cells from human skin Co-cultures of primary cells
Fibroblasts, Keratinocytes Fibroblasts/Keratinocytes
Subcutis (Melanocytes) (Keratinocytes/Melanocytes)

Fat management Primary cells from hair follicles Cell lines

* Skin derived from animals
• Catabolism (lypolysis) Fibroblasts, Keratinocytes Fibroblasts, Keratinocytes, slaughtered for meat
• Glucose metabolism (Melanocytes) Melanocytes ° Development in progress
Sophisticated screening
services for the beauty and
health industry
SCoutech is a highly specialized biotechnology joint venture
focusing on skin and hair. We offer screening services for cosmetic
raw materials (both skin and hair), cosmetic formulations (skin),
nutraceuticals and pharmaceuticals. We support our customers
by researching both the efficacy and the mode of action of new
potential products.

We use cell- and tissue-based screening assays to support the

development of effective products for skin and hair care.

With all the models we use, including our groundbreaking patented

PSOCM (Pig Skin Organ Culture Model), we provide both reliable
and ethical test procedures. Our screening services are in full
compliance with the EC directive which bans animal testing on
personal care products.

Contact:
Fields of activity SCoutech
c/o Cutech srl
• Personal care industry via Uruguay 53
In vitro and ex vivo efficacy testing I-35127 Padova
Italy
• Nutraceuticals industry
Claim support Phone/Fax: +39 049 762 8532

• Pharmaceuticals industry e-mail: info@scoutech.it

Preclinical research www.scoutech.it
SCoutech is a joint venture of Cutech and Symrise.
Cutech is a biotech company that focuses on designing highly informative screening tools as an
alternative to animal testing. Symrise has wide experience in developing and producing innovative
raw materials and compositions for the personal care, food and pharmaceutical industries. The Screening Services
skills of these companies have merged in a joint venture that aims to provide their customers with
solutions which verify both the efficacy and the mechanism of action of their products. for Hair and Skin
Sophisticated screening
services for the beauty and
health industry
SCoutech is a highly specialized biotechnology joint venture
focusing on skin and hair. We offer screening services for cosmetic
raw materials (both skin and hair), cosmetic formulations (skin),
nutraceuticals and pharmaceuticals. We support our customers
by researching both the efficacy and the mode of action of new
potential products.

We use cell- and tissue-based screening assays to support the

development of effective products for skin and hair care.

With all the models we use, including our groundbreaking patented

PSOCM (Pig Skin Organ Culture Model), we provide both reliable
and ethical test procedures. Our screening services are in full
compliance with the EC directive which bans animal testing on
personal care products.

Contact:
Fields of activity SCoutech
c/o Cutech srl
• Personal care industry via Uruguay 53
In vitro and ex vivo efficacy testing I-35127 Padova
Italy
• Nutraceuticals industry
Claim support Phone/Fax: +39 049 762 8532

• Pharmaceuticals industry e-mail: info@scoutech.it

Preclinical research www.scoutech.it
SCoutech is a joint venture of Cutech and Symrise.
Cutech is a biotech company that focuses on designing highly informative screening tools as an
alternative to animal testing. Symrise has wide experience in developing and producing innovative
raw materials and compositions for the personal care, food and pharmaceutical industries. The Screening Services
skills of these companies have merged in a joint venture that aims to provide their customers with
solutions which verify both the efficacy and the mechanism of action of their products. for Hair and Skin