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SESSION 4

1.D- Polypharmacy refers to a potentially inappropriate combination of medications. While it is true that
a higher number of medications puts patients at risk of polypharmacy, it is not in and of itself indicative
of polypharmacy.

2. D- Two keys to managing medication use in the elderly are accurate medication listing and
assessment of compliance. A ―brown-bag review‖ of medications, where the patient takes all of his or
her medicines to the doctor’s office, can be an effective way of not only gauging the true list of
medications but also detecting any problematic medications. Just as important is assessing patient
adherence to the medication regimen.

3. D- Drug absorption from the GI tract is slowed in the older adult because of decreases in both blood
flow and GI motility.

4. B- The gastrointestinal system of an older adults decreases or having a slower functions that caused
the tablets to dissolved more slowly.

5. D- The drugs in older population will be excreted less readily because they have a slow organ
functioning already as they aged.

6. C- As the people aged they can have an altered pH of the stomach contents which leads a physiologic
changes of drug absorption.

7. D- Renal function declines in older adults, leading to decreased excretion and potential drug
accumulation. Although absorption may be delayed in older adults, the percentage absorbed does not
change. Most older adult patients have increased body fat and decreased lean mass. Hepatic
metabolism tends to decline with age.

8. D- Although pharmacokinetic changes in older adults affect all phases of kinetics, drug accumulation
secondary to reduced renal excretion is the most important cause of ADRs in the older adult

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