Generic name Trade name Indication Adverse effect Side effect contraindicati

Atropine ATROPAIR anti-sialagogue/anti-vagal Tachycardiac Dry mouth Patient with

effect, Cns : restless, Blurred narrow- angle
organophosphate/muscarini
c poisoning, and confusion vision glaucoma
bradycardia ,hallucination Constipation

Hyosine BUSCOPAN  the relief of spasm of the Constipation, myasthenia

genito-urinary tract or dry mouth, gravis,
gastro- intestinal tract and trouble
for the symptomatic relief of urinating, or
Irritable Bowel Syndrome. nausea

Homatropine HOMAPIN Opthalmic use for Fixed dilated pupil, increased primary angle-
mydriasis & cycloplegia ocular pressure; light closure glauco
sensitivity, hyperthermia.

Cholinergic antagonist ( anti mucsarinic agents )

GANGLION BLOCKER

Generic name Trade name Indication Adverse Side effect Contraindic

effect
Nicotine NICORETTA Reducing the carving Irritation and burning
NICOTENEL TTS for nicotine sensation in the mouth
and throat, increased
salivation,nausea,
abdominal pain,
vomiting and diarrhea

NEUROMUSCULAR BLOCKER

Generic name Trade name Indication Adverse effect Side Effect Contraindicatio
Tubocurarine TUBOCURARINE Used as adjuvant Low blood Bronchospasm patients with
CHLORIDE drug in pressure neuromuscular
Itchy disease. 
anesthesia during Rash
surgery to relax
skeletal muscle

Succinylcholine ANETINE Used when rapid Hyperthemia - hyperkalemia

incubation is when used with
required during halothane
The induction of Apnea( temporary
anesthesia cessation of
breathing )
CHOLINERGIC AGONIST ( DIRECT ACTING )

GENERIC TRADE NAME INDICATION ADVERSE EFFECT SIDE EFFECT CONTRAINDIC

NAME
Carbachol MIOSTAT -miosis during Burning , sting Asthma
ocular surgery Tearing eyes Peptic ulcer d
-reduce Headache
intraocular
pressure in
open angle
glaucoma
Pilocarpine ISOPCARPINE -miotics in -can enter the brain and uncontrolled a
chronic open cause CNS Disturbance
angle =profuse sweating,
glaucoma salivation ,headache,blurred
vision
TIMOLOL TIMOPTOL -Reducing Temporary bronchial asth
MALEATE 0.5 % BLOCADREN amount of fluid blurred vision,
temporary
EYE DROP in the aqueous burning
humour Stinging
Itching
redness of the
eye
watery eyes,
dry eyes, 
latanapprost XALATAN Increase aquos change in eye Closed angle
humor colour  glaucoma
redness of the
drainage eye
irritated eye and
eye pain

ANTICHOLINTERASES ( REVERSIBLE )

GENERIC TRADE NAME INDICATION ADVERSE EFFECT SIDE EFFECT CONTRAINDICATION

NAME

Neostigmine PROSTIGMINE -Myasthenia Salivation a hypersensitivity to

gravis Decreased BP neostigmine
-reversai Nausea
neuromuscular Diarrhea
block ( antidote Bronchospasm
tubocurarine)
Physostigmine ANTILIRIUM -reduce vomiting, diarrhea, Pulmonary disease-ca
intraocular abdominal cramps, bronchoconstriction o
diaphoresis airways such as asthm
pressure in
glaucoma
ANESTHETICS (INTRAVENOUS ANESTHETICS )

GENERIC NAME TRADE NAME INDICATION ADVERSE EFFECT SIDE EFFECT CONTRAINDICATIO

Short acting Pentottal the induction of respiratory 1. myasthen

barbiturates general depression, gravis, a skelet
anaesthesia myocardial muscle disorde
Thiopental   used as an depression,
sodium adjunct to provide cardiac
hypnosis during arrhythmias,
balanced prolonged
anaesthesia with somnolence and
other anaesthetic recovery,
agents, including sneezing,
analgesics and coughing,
muscle relaxants. bronchospasm,
laryngospasm
and shivering.

Benzodiazepines Midazolam used before hiccoughs, narrow-angle

Diazepam medical cough, nausea, glaucoma
procedures and and vomiting
Lorazepam surgery to cause
drowsiness, relieve
anxiety, and
prevent any
memory of the
event. 

Etomidate Amidate commonly Excitatory Patient w/ cortico-

Hyponimade . used sedative phenomena e.g. adrenal insufficiency
during rapid myoclonus; pain on (e.g. patient w/ sepsis)
sequence inj site; pre-existing epilepsy,
intubation (RSI). hyperventilation, hepatic cirrhosis. Rena
hypoventilation, impairment. Elderly an
apnoea, hiccups childn. Pregnancy and
and snoring, HTN, lactation.
hypotension,
postoperative
nausea and
vomiting. Rarely,
convulsions,
cardiac
arrhythmias,
laryngospasm.
Propofol Diprivan -used to put you epilepsy or other
to sleep and keep seizure disorder
a light-headed mild itching or
you asleep during
feeling (like you rash;
general
might pass out) fast or slow
anesthesia for
even after heart rate; or
surgery or other
feeling awake; slight burning
medical
weak or shallow or stinging
procedures.
breathing; or around the IV
-also used to
severe pain or needle.
sedate a patient
discomfort
who is under
where the
critical care and
injection is given.
needs a
mechanical
ventilator
(breathing
machine).

Ketamine ketalar a Seizure Hypersensitivity.

general anesthetic indicat
ed as the sole anesthetic Double vision Conditions in which
agent for diagnostic and Palpitation an increase in blood
surgical procedures that pressure would be
do not require skeletal
muscle relaxation
hazardous.
 INHALATION ANESTHETIC

GENERIC TRADE NAME INDICATION ADVERSE SIDE EFFECT CONTRAINDICATION

NAME EFFECT

Nitrous oxide Entonox commonly used  headaches  pneumothorax, small

(gas) for sedation and nausea. bowel obstruction,
and pain relief, Children may middle ear surgery,
Laughing gas but is also used also feel and retinal surgeries
by people to agitated or involving the creation
feel intoxicated might vomit of an intraocular gas
or high. It is after the bubble. In laparoscopic
commonly used laughing gas is cases, nitrous oxide
by dentists and removed can accumulate in the
medical pneumoperitoneum,
professionals to and some avoid its use
sedate patients in these cases.
undergoing
minor medical
procedures.
Halogenated Fluothane  indicated patients with increased
hydrocarbon for the -hepatitis. intracranial pressure or
induction and intracranial
(Volatile ) -kidney
maintenance hemorrhage. 
Halothane damage.
of general
anesthesia. -malignant
hyperthermia.
-problems with
circulation.
-yellowing of
skin or eyes
(jaundice)

Enflurane ETHRANE induction and  elevated body

maintenance temperature,
of general seizures, low
anesthesia. blood
pressure, slow
or shallow
breathing, low
blood oxygen,
heart
arrhythmias,
shivering,
chills, nausea,
vomiting, or
liver damage

Isoflurane Forane general Shivering, malignant

inhalation nausea, hyperthermia.
anesthetic used vomiting and
for induction ileus
and
maintenance of
general
anesthesia. It
induces muscle
relaxation and
reduces pains
sensitivity by
altering tissue
excitability.
 ANTIDEPRESSANT (AMINE REUPTAKE INHIBITOR)

SELECTIVE SEROTONIN REUPTAKE INHIBITOR (SSRI)

GENERIC NAME TRADE NAME INDICATION MOA SIDE EFFECT CONTRAINDICATION

Flouxetine PROZAC used to Inhibit the feeling sick  those patients

treat depression, reuptake of (nausea), with fluoxetine
obsessive- headaches and hypersensitivity or
compulsive seratonin trouble hypersensitivity 
disorder sleeping.

Fluvaxamine LUVOX  indicated for the Inhibit the  Headache,

treatment of reuptake of nausea,
obsessions and diarrhea, dry
compulsions in seratonin mouth,
patients with dizziness,
obsessive increased
compulsive sweating,
disorder (OCD), feeling
nervous,
restless,
fatigued, or
having trouble
sleeping
(insomnia).
Sertraline ZOLOFT the treatment Inhibit the a disorder with excess
of obsessive- reuptake of nausea, loss of antidiuretic hormone
compulsive appetite, called syndrome of
disorder, panic seratonin diarrhea, and inappropriate antidiuret
disorder, post- indigestion.  hormone.
traumatic stress
disorder,
premenstrual
dysphoric
disorder, and
social anxiety
disorder.

TRICYCLIC ANTIDEPRESSANTS (TCAs)

GENERIC TRADE INDICATION MOA SIDE EFFECT CONTRAINDICATION

NAME NAME
Amitriptyline TRYPTANOL -the treatment of major -inhibit the neuronal -dry mouth Orthostic
depressive disorder and re-uptake of -weight gain hypotension
neuropathic pain and for noradrenaline -sedation
the prevention of
migraine and chronic &serontin -blurred vision
tension headache -blocking the - sexual
serotonergic,a- dysfunction
adnergic, -constipation
muscarinic ,histaminic

Clomipramin ANAFRANIL the treatment of inhibit the neuronal Dizziness, -serotonin syndrome,

e obsessions and re-uptake of drowsiness, dry a type of disorder with
compulsions in patients mouth, high serotonin levels.
with Obsessive- noradrenaline constipation, -Closed angle
Compulsive Disorder &serontin stomach upset, glaucoma
(OCD). -blocking the nausea, vomiting,
serotonergic,a- changes in
appetite/weight,
adnergic, flushing,
muscarinic ,histaminic sweating,
tiredness and
blurred vision 

Imipramine TOFRANIL  used to treat depression. inhibit the neuronal Dry mouth, -serotonin syndrome,
It is also used with other re-uptake of blurred vision, a type of disorder with
therapies for the headache, high serotonin levels.
treatment of nighttime noradrenaline drowsiness,
&serontin -alcoholism
-bedwetting (enuresis) in dizziness,
children. -blocking the constipation,
serotonergic,a- nausea, vomiting,
loss of appetite,
adnergic, diarrhea, stomach
muscarinic ,histaminic cramps, weight
gain/loss

MONOAMINE OXIDASE INHIBITORS (MAOI)

GENERIC NAME TRADE INDICATION MOA SIDE EFFECT CONTRAINDICATION

NAME
 Phenelzine NARDIL the management of -incresed -dry mouth
treatment-resistant neurotrasmitter -weight gain
depression, panic
disorder, and social (NE,D &Serotonin) - sedation
anxiety disorder. into synaptic space -blurred vision
-used for  young women -to inactive -sexual
who have depression monoamine dysfunction
and mood disorders
neurotransmitter -constipation
-orthostiatic
hypotension
Tranylcypromine PARNATE  for the treatment of -incresed Dizziness,
major depressive neurotrasmitter drowsiness,
disorder (MDD) in adult tiredness,
patients who have not (NE,D &Serotonin) weakness,
responded adequately into synaptic space problems sleeping,
to other -to inactive constipation, and
antidepressants. monoamine dry mouth
neurotransmitter

CNS STIMULANT

GENERIC NAME TRADE INDICATION MOA SIDE EFFECT CONTRAINDICATION

NAME
Amphetamine -Adzenys XR- the treatment  -increasing -rapid heart rate -cardiovascular
ODT, of attention- dopamine levels in
-Dyanavel XR deficit/hyperactivity the brain. disease or
- Evekeo disorder (ADHD) and -abdominal pain arteriosclerosis, a
narcolepsy
thickening or
-loss of appetite, hardening of artery
nausea, and weight walls
loss
-
-acne, rash, hives

-blurred vision

-dry mouth

-teeth grinding

methamphetamine Desoxyn, -used of psychoactive -violent behavior

Methedrine drug to indiced an -paranoia
altered state of -anxiety
consciousness for -confusion
pleasure -insomnia
Phentermine ,  Adipex P, -used to suppress - a -Increased heart rate -overactive thyroid
Sibutramine Lomaira appetite.  sympathomimetic -Tingling or prickling gland.
amine that works feeling in hands or -diabetes.
on the central feet. -psychotic disorder.
nervous system
-Dry mouth. -alcoholism.
to suppress
appetite. -Sleeplessness.
-Nervousness.
-Constipation.

Cocaine Neurocaine, For the introduction of  inhibiting -euphoria patients with a

Goprelto, local (topical) excitation of nerve -hallucination history of allergy or
Numbrino anesthesia of endings or by hypersensitivity to
accessible mucous blocking -delusion the drug
membranes of the oral, conduction in -paranoia
laryngeal and nasal peripheral nerves
cavities.

Caffeine Cafcit  generic stimulates the increases energy -Restlessness and Symptomatic or
brain; hence it is used metabolism shakiness. history of cardiac
as a central nervous throughout the -Insomnia. arrhythmia, anxiety
stimulant. It is used brain but
-Headaches. disorders.
along with analgesics decreases at the
and/or ergotamine for same time -Dizziness. Concomitant use
migraine (severe cerebral blood with other xanthines
headaches with flow, inducing a
nausea). It is also used relative brain
for a breathing hypoperfusion.
condition (apnea) in
premature infants.
Nicotine Nicorette, used to help treat -act as agonist at -Decreased appetite. severe eczema or
Nicotrol addiction to or serious skin
most nicotinic -Heightened mood.
dependence on conditions
acetylcholine -Increased activity in
smoking cigarettes.
receptor the intestines.
-Increased production
of saliva and phlegm.

PSYCHOSES AND SCIZOPHRENIA

Generic name Trade name Indication MOA Side effect Contraindication

PHENOTHIAZINE Largactil  used to treat serious antagonists of 5- Constipation,  hypertensive or
-chlopromazine Stealizine mental and emotional HT and dopamine trouble urinating, hypotensive heart
disorders, receptors in the dryness of mouth, disease of extreme
-trifluoperazine including schizophrenia chemoreceptor confusion, degree 
and other psychotic trigger zone. In problems with
disorders. addition, they act as memory, dizziness
an alpha-adrenergic or fainting,
antagonist. drowsiness,
trembling of the
hands and
fingers, 
BUTYROPHENONE Serenace used to treat psychoses   blocking drowsiness,  Parkinson's
S Haldol dopamine- restlessness, disease;
mediated synaptic dizziness,
-haloperidol neurotransmissio headache, blurred
n by binding to vision, tremor,
dopamine weight gain, and
receptors occasionally mild
liver injury
COMMON ADDED DRUG

Generic name Trade name Indication MOA Side effect Contraindication

Benzhexol Artane To treat the blocking a certain Drowsiness, patients with
stiffness,tremors,spas natural substance dizziness, hypersensitivity to
(acetylcholine) constipation, trihexyphenidyl
m and poor muscle flushing, nausea, HCl 
movement nervousness,
blurred vision
ATYPICAL NEUROLEPTICS

GENERIC NAME TRADE NAME INDICATION MOA SIDE EFFECT CONTRAINDICATION

Dibenzodiazepines CLOZARIL to treat schizophrenia. the blocking of 5- -sedation -diabetes.
-CLOZAPINE It  HT2A/5-HT2C serot -weight gain -excessive fat in the
onin receptors blood.
and the D1-4 -hypotension
-low amount of
dopamine
magnesium in the
receptors, 
blood.

Thienobenzodiazepi ZYPREXA for acute treatment of blocking receptors Drowsiness, -diabetes.

nes manic or mixed for several dizziness, -a high prolactin
episodes associated neurotransmitters lightheadedness, level.
-olenzapine with Bipolar I in the brain stomach upset,
-high cholesterol.
Disorder  dry mouth,
constipation, -high amount of
increased triglyceride in the
appetite, or weight blood.
gain -excessive fat in the
blood.
Benzisoxazoles RISPEDAL  the treatment of decrease -nausea. -breast cancer.
- Resperidone irritability associated dopaminergic and -vomiting. -diabetes.
with autistic serotonergic
-diarrhea. -a high prolactin
disorder,also used for pathway activity
-constipation. level.
bipolar in the brain, 
-excessive fat in the
blood.

Dibenzothiazepines SEROQUEL the treatment of both: -hyperglycemia -breast cancer.

-Quetiapine • depressive episodes -a condition with low
associated with thyroid hormone
bipolar disorder  levels.
-diabetes.
-a high prolactin
level.

PARKINSONIAN ( DOPAMINE AGONIST )

GENERIC NAME TRADE INDICATION MOA SIDE EFFECT CONTRAINDICATION

NAME
Levodopa- SINEMET  used to treat converted to dopamine Dizziness, patients with
carbidopa symptoms of via the action of a lightheadedness, narrow-angle
Parkinson's naturally occurring nausea, vomiting, glaucoma
disease or enzyme called DOPA loss of appetite,
Parkinson-like decarboxylase.  trouble sleeping,
symptoms unusual dreams, or
headache 
Levodopa and MADOPAR  treat Parkinson's -enhance the effect of Dizziness,
benserazide disease levodopa in the CNS lightheadedness,
nausea, vomiting,
- diminishes the loss of appetite,
metabolism of trouble sleeping,
levodopa in GIT unusual dreams, or
&peripheral tissues headache 

GENERIC NAME TRADE INDICATION MECHANISM OF SIDE EFFECT CONTRAINDICATION

NAME ACTION
SELEGILINE JUMEX MAO-typeb -prevent the -orthostatic
inhibitor breakdown of hypotension
dopamine by inhibit -dizziness
MOA-B -psychosis
 -depression
- hallucination
ENTACAPONE COMTAN COMT inhibitor -inhibit COMT -nausea& vomiting -patient with hepatic
-increase -headache impairment
concentration of -dyskinesia -patient with biliary
dopamine in the brain -dizziness obstruction
-diarrhea -cannot should
-constipation abruptly
AMANTADINE SYMMETRE Dopamino -increase dopaminergic -nausea
L anticholinergic decrease cholinergic -dizziness
activity activity -insomnia
-confusion