Keyword: deficiency in galactosylceramidase

The correct answer is: Krabbe's Disease

Which of the following is true regarding topoisomerase I

I. Topoisomerase I reversibly cuts one strand of DNA
II. Topoisomerase I both have nuclease and ligase activity
III. Topoisomerase I requires ATP to be able to reseal the broken
strands
IV. Topoisomerase I relieves positive supercoils in E. coli while it relieves
both positive and negative supercoils in eukaryotic DNA

a.
No statement is correct

b.
1 of the statements is correct

c.
2 of the statements are correct

d.
3 of the statements are correct

e.
All of the statements are correct
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Topoisomerase I Topoisomerase 21
1 strand 2 strands
No ATP required ATP requiring
Relieves negative Introduces negative
supercoils in E. coli. supercoils
Both positive and
negative in eukaryotes
Topoisomerase I reversibly cuts one strand and has nuclease and ligase
activity. Topoisomerase DOES NOT use ATP to reseal the broken
strands. It uses the energy released by the cleaved phosphodiesterase
bonds during the strand cutting stage. Topoisomerase relieves
NEGATIVE supercoils in E. coli.
Reference: Lippincott Biochemistry, pg. 401

The correct answer is: 2 of the statements are correct

Which of the following is true regarding topoisomerase II

I. Relieving of supercoils using Topoisomerase II is not an ATP
requiring process.
II.  Topoisomerase II causes a transient break in both strands.
III. Topoisomerase II cannot relieve negative supercoils.
IV. Topoisomerase II in bacteria and plants can introduce negative
supercoils.

a.
No statement is correct 

b.
1 of the statements is correct

c.
2 of the statements are correct

d.
3 of the statements are correct

e.
All of the statements are correct
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Topoisomerase I Topoisomerase 21
1 strand 2 strands
No ATP required ATP requiring
Relieves negative Introduces negative
supercoils in E. coli. supercoils
Both positive and
negative in eukaryotes

transient break in both strands. It can relieve both negative and positive
supercoils. Topoisomerase II can introduce negative supercoils. The
negative supercoils facilitates future replication of DNA because the
negative supercoils neutralize the positive supercoils caused by
unwinding in the replication fork.
Reference: Lippincott Biochemistry, pg. 401

The correct answer is: 2 of the statements are correct

Initiates leading strand synthesis.

a.
Pol-Alpha

b.
Pol-Beta

c.
Pol-Gamma

d.
Pol-Delta

e.
Pol-Epsilon
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The correct answer is: Pol-Delta
Question 17
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Involved in repair of broken parts of the leading strand
a.
Pol-Alpha

b.
Pol-Beta

c.
Pol-Gamma

d.
Pol-Delta

e.
Pol-Epsilon
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The correct answer is: Pol-Beta

Responsible for the elongation of the Okazaki fragments in the lagging

strand

a.
Pol-Alpha

b.
Pol-Beta

c.
Pol-Gamma

d.
Pol-Delta

e.
Pol-Epsilon
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The correct answer is: Pol-Alpha
Question 20
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Which of the following features are unique to the strand being
synthesized in the direction away from the origin of replication?

a.
Elongation without any pause or breaks

b.
Presence of Okazaki fragments

c.
Use of multiple primers

d.
Two of the choices

e.
All of the choices
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The correct answer is: Elongation without any pause or breaks

Mammals solve the problem of ammonia toxicity by converting the said

substance to urea, a soluble nitrogenous compound which is less toxic
than ammonia. The following is/are true regarding urea cycle:
I. The first phase of urea cycle occurs in the cytosol while the
second phase proceeds in the mitochondria
II. II. Urea cycle is an ATP requiring process.
III. III. Formation of Carbamoyl phosphate and citrulline occurs in
 the cytosol
IV. IV. One mole of ATP is needed to produce one mole of
carbamoyl phosphate

a.
I only

b.
I and III

c.
II only

d.
II and IV
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·       The first phase of urea cycle, which produces carbamoyl phosphate
and citrulline occurs in the MITOCHONDRIA and the subsequent
reactions proceed in the cytosol.
·       It is an ATP requiring process, specifically requiring TWO moles of
ATP per mole of carbamoyl phosphate produce. It follows this reaction:
NH4+ +HCO3- + 2 ATP → Carbamoyl phosphate + 2 ADP + 2 p
Reference: Lehninger Buiochemistry for Pharmaceutical Science p. 389.

The correct answer is: II only

Neroli Oil

a.
Ketone

b.
Hydrocarbon

c.
Alcohol
d.
Oxide
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Neroli- Bitter Orange (Citrus aurantium)
The correct answer is: Alcohol
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Orange Oil

a.
Aldehyde

b.
Oxide

c.
Ester

d.
Ketone
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The correct answer is: Aldehyde
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Cajuput Oil

a.
Alcohol

b.
Phenol

c.
Phenolic ether

d.
Oxide
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The correct answer is: Oxide
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Buchu Oil

a.
Ester

b.
Ketone

c.
Hydrocarbon

d.
Alcohol
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Borosma betulina
The correct answer is: Ketone

Which of the following plants produce a blue colored oil?

a.
Achillea millefolium

b.
Humulus lupulus

c.
Juniperus communis

d.
Syzigium aromaticum
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Achillea millefolium- Common Yarrow
Humulus lupulus-- Hops
Juniperus communis- Juniper
Syzigium aromaticum- Cloves

The correct answer is: Achillea millefolium

Identify the corresponding botanical origin of Tea Tree Oil

a.
Melaleuca alternifolia

b.
Camella sinensis

c.
Chamamaelum nobile

d.
Cymbopogon nardus
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Melaleuca alternifolia- tea tree
Camella sinensis- tea plant
Chamamaelium nobile- Chamomile
Cymbopogon nardus- Citronella

The correct answer is: Melaleuca alternifolia

Question 67
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Identify the corresponding botanical origin of  Dill Oil

a.
Pinus mugo

b.
Salvia officinalis

c.
Pinus palustris

d.
Anethum graveolens
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Pinus mugo- mountain pine
Salvia officinalis- Sage
Pinus palustris- Pine
Anethum graveolens- Dill

The correct answer is: Anethum graveolens

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Identify the corresponding botanical origin of Dwarf mountain pine oil

a.
Pinus mugo

b.
Melaleuca alternifolia
c.
Citrus aurantium

d.
Cinnamomum camphora
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The correct answer is: Pinus mugo
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Identify the corresponding botanical origin of Sandalwood Oil

a.
Mentha spicata

b.
Santalum album

c.
Rosmarinus officinalis

d.
Salvia officinalis
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The correct answer is: Santalum album
Question 70
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Identify the corresponding botanical origin of Sage Oil

a.
Citrus sinensis
b.
Thymus vulgaris

c.
Salvia officinalis

d.
Juniperus communis
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The correct answer is: Salvia officinalis

This polysaccharide is the most branched among the options, and

therefore has potentially faster capability to release glucose when the
animal in question is in great need for energy.

a.
Starch

b.
Cellulose

c.
Glycogen

d.
Inulin
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The correct answers are: Glycogen, Inulin

Question text
Arrange the following steps within the cell cycle in chronological order:
I. The nucleus reforms and the cytoplasm divides.
II. The kinetochore of dyad chromosomes become attached to mitotic
spindles.
III. Cohesin proteins break down and the sister chromatids separate.
IV. Sister chromatids then line up at the metaphase plate
a.
III, II, IV, I

b.
II, IV, III, I

c.
II, I, III, IV

d.
III, I, IV, II
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The correct answer is: II, IV, III, I
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The mitotic spindles arise from which cell structure?

a.
Centromere

b.
Centrosome

c.
Kinetochore

d.
Cleavage furrow
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Centromere- spindle fibers attach to centromere via kinetochore
Centrosome- organelle near the nucleus which contains centrioles from
which spindle fibers develops
The correct answer is: Centrosome
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The fusing of Golgi vesicles at the metaphase plate of dividing plant cells
forms what structure?

a.
cell plate

b.
cleavage furrow

c.
mitotic spindle

d.
actin ring
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The correct answer is: cell plate

Which feature in the central dogma is critical to RNA synthesis from a

DNA template strand?

a.
Shine-Dalgarno sequence

b.
Promoter regions

c.
Helicase

d.
7-methylguanosine molecules
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The correct answer is: Promoter regions
Question 89
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Glycosylating newly synthesized proteins can serve a variety of
functions, including the following except one. Which is the wrong
statement?

a.
Target them to specific organelles like the cell membrane
b.
Give rise to different blood types such as type A, B, and AB

c.
Grant them the capability to provide energy upon degradation

d.
Confer some peptides their native conformation by giving interactions for
folding
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The correct answer is: Grant them the capability to provide energy upon
degradation
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Which among the following choices is an/are anabolic process(es)?
I. Glycogenesis
II. Glycogenolysis
III. Fermentation
IV. Glycolysis

a.
II and IV

b.
I and III

c.
I only

d.
III only
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The correct answer is: I only
Arrange the following in chronological order
I. Bile acids aid in digestion and absorption of dietary lipids by
emulsification.
II. Short and medium chain fatty acids are absorbed via stomach wall
and enter the portal vein.
III. Gastric lipase degrade TAG molecules.
IV. Longer chain fatty acids are passed on to the duodenum
V. Pancreatic lipases digest dietary TAGs.
VI. Lingual lipase catalyze the breakdown of TAG molecules

a.
I, II, III, IV, V, VI

b.
VI, III, II, IV, I, V

c.
III, II, I, IV, V, VI

d.
IV, III, II, I, V, VI
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The correct answer is: VI, III, II, IV, I, V

Which of the following hormones is produced when gastric contents

enter the duodenum?

a.
Cholecystokinin

b.
Gastrin

c.
Secretin
d.
Motilin
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The correct answer is: Cholecystokinin