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It is used to express the rate at which a solid dissolves in a solvent:

Fick law’s – rate of diffusion


Hixson Crowell Cube Root Law – describes the release from system
where there is a change in surface area and diameter of the tablet or
particles
Stokes’ Law – Rate of sedimentation
Gay-Lussac’s Law – Relation of temperature and pressure

The correct answer is: Noyes-Whitney Equation

As light passes from air into a liquid it slows down. This phenomenon is
what gives a "bent" look to objects that are partially submerged in water.
The correct answer is: Abbe refractometer

This is used to determine the optical rotation of a chiral molecule


The correct answer is: Polarimeter

Measures the emission of visible light by a substance that has absorbed


light of a different wavelength
The correct answer is: Fluorimeter

Routinely used in analytical chemistry for the quantitative determination


of different analytes. It measures the attenuation of a beam of light after
it passes through a sample or after reflection from a sample surface
The correct answer is: UV spectrophotometer

Characteristics of amorphous solids include all of the following, EXCEPT

a.
They tend to flow when subjected to sufficient pressure over time

b.
They do not have definite melting points

c.
They exhibit isotropicity

d.
They have randomly arranged molecules

e.
They exhibit polymorphism
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Amorphous Crystalline
Randomly arranged Ordered structure
molecules Sharp MP
Do not have a sharp MP Anisotropic
Isotropic Covalent, Ionic, Van der
Covalently bonded Waals, metallic bonds
networks

The correct answer is: They exhibit polymorphism

Which of the following statements is/are true?


I. The Liso value for a 0.9% solution of sodium chloride, which has a
freezing point depression of 0.52  and is thus isotonic with body fluids,
is 3.4
II. In dilute solutions of nonelectrolytes, Liso is approximately equal to Kf
III. The interionic attraction in solutions that are not too
concentrated is roughly the same for all uni-univalent
electrolytes regardless of the chemical nature of the various
compounds of this class, and all have about the same value
for Liso, namely 3.4
The correct answer is: All of the above

Type of complexation involved in Starch-Iodine complex

a.
Clathrate

b.
Monomolecular

c.
Channel lattice

d.
Chelation

e.
Layer

Clathrate: Hydroquinone, Warfarin sodium


Monomelcular: Gamma-cyclodextrin
Channel lattice: Urea and thiourea, Deoxycholic acid
Chelation: Ca-EDTA
Layer: clay montmorillonite complexes, graphite

The correct answer is: Channel lattice

Reaction order used for long-term stability studies


First order reaction is used for accelerated stability studies
The correct answer is: Zero order

Refers to persons who assist the pharmacist in the different aspects of


pharmacy operation based on established standard operating
procedures, with very minimal degree of independence, and without
direct interaction with patients

a.
Pharmacy Technician

b.
Pharmacy Assistant
c.
Pharmacist

d.
Pharmacy Aide

e.
Pharmacist Prescriber
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Pharmacy Technician- Refers to persons who assist in compounding
and dispensing of medicines under the supervision of a pharmacist
Pharmacy Assistant- Refers to persons who assist the pharmacist in the
different aspects of pharmacy operation based on established standard
operating procedures, with very minimal degree of independence, and
may have supervised interaction with patients

The correct answer is: Pharmacy Aide

S Licenses (dangerous P Licenses (controlled


drugs) precursors and essential
chemicals)
S-1 exempt dangerous P-1 retailer
drugs P-3 end user
S-2 prescribers P-4 wholesaler
S-3 retailers P-5C compounder
S-4 wholesalers P-5D bulk depot/
S-5-I importer storage
S-5-C compounder P-5E exporter
S-5-E exporter P-5I importer
S/P-6 researcher, P-5IM importer and end-
laboratory analysis user
S/P-7 importer and P-6 research/analysis/
compounder instructional program
The correct answer is: P-3

Amphetamine-Bennies
Amytal- Downer
Codeine- School boy
Demerol- Demies
Heroin- Downtown
Marijuana- Grass
MDMA- Love drug
Mescaline- Cactus
Morphine- Emma
Nembutal- Yellow
Peyote- Ganja
Phenycyclidine- Crystal
Trional-Rainbow

A.O. 55- Labeling materials of pharmaceutical products


A.O. 56- Licensing of drug establishments and outlets
A.O. 62- Prescribing Requirements
A.O. 63- Dispensing Requirements
A.O. 90- Allowing more than 1 drug in a prescription

The essential property to be possessed by tablet granulation is:


I. Plasticity
II. Compressibility
III. Fluidity
IV. Porosity

a.
I AND II
b.
II AND III

c.
III AND IV

d.
I AND IV

e.
ALL OF THE ABOVE
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The correct answer is: II AND III

Rapidly disintegrating or dissolving tablets are designed to dissolve in


the mouth within
The correct answer is: 15 seconds

Alcohol limit in oral OTC products for children  6-12 years old
Under 6 yrs- 0.5%
Over 12 yrs- 10%
The correct answer is: 5%

Properties of flocculated particles in suspension, EXCEPT

a.
Particles form loose aggregates

b.
Rate of sedimentation is high

c.
Sediment is formed rapidly
d.
Sediment is closely packed

e.
Suspension is somewhat unsightly
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Sediment is closely packed
Sediment is loosely packed

The correct answer is: Sediment is closely packed

Container of choice for ointments:

a.
Jar

b.
Can

c.
Blister pack

d.
Wide-mouth bottle

e.
Collapsible tube
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The correct answer is: Collapsible tube
This robust mixer deals with stiff pastes and ointments and depends its
action on the close intermeshing of the two blades

a.
Planetary mixer

b.
Tumbling mixer

c.
Agitator mixer

d.
Sigma-blade mixer

e.
Fluidized-bed mixer
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The correct answer is: Sigma-blade mixer

This defect results from inadequate spreading of the coating solution


before drying causing a bumpy effect on the coating:
The correct answer is: Orange Peel

When coated tablets require further drying in ovens, too rapid


evaporation of the solvent from the core and the effect of high
temperature on the strength, elasticity, and adhesion of the film may
result to this defect
The correct answer is: Blistering

This is called bloom because it can occur when too high a processing
temperature is used for a particular formulation:
The correct answer is: Hazing/Dull Film

Lamination- separation of the tablet into 2 or more distinct layers


Presence of a crack in a bottle is an example of what defect

a.
Internal

b.
External

c.
Major

d.
Minor

e.
Critical
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object rendering it useless
Internal defect is a defect which is not seen although present
Critical defect is life-threatening

The correct answer is: Major

The particles in an ideal suspension should satisfy which of the following


criteria?
I. Their size should be uniform
II. They should be stationary or move randomly
III. They should remain discrete

a.
Statement I only is correct

b.
Statement III only is correct

c.
Statements I and II are correct

d.
Statements II and III are correct

e.
Statements I, II, and III are correct

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The correct answer is: Statements I, II, and III are correct
Question 96
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Mechanisms that are thought to provide stable emulsification include the
I. formation of interfacial film
II. lowering of interfacial tension
III. presence of charge on the ions

a.
Statement I only is correct

b.
Statement III only is correct

c.
Statements I and II are correct

d.
Statements II and III are correct

e.
Statements I, II, and III are correct
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The correct answer is: Statements I, II, and III are correct
Question 97
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True statements about the function of excipients in tablet formulations
include
I. Binders promote granulation during the wet granulation process
II. Glidants help promote the flow of the tablet granulation during
manufacture
III. Lubricants help the patient swallow the tablet

a.
Statement I only is correct

b.
Statement III only is correct

c.
Statements I and II are correct

d.
Statements II and III are correct

e.
Statements I, II, and III are correct
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The correct answer is: Statements I and II are correct

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