VIRAL INFECTIONS OF THE SKIN VIRAL INFECTIONS OF THE EYES
Chickenpox (also known as varicella) Adenoviral Conjunctivitis and
Symptoms: fever and skin rashes Keratoconjunctivitis Prevention: Airborne and Contact Precautions Symptoms: inflammation of the conjunctiva, Virus: Varicella- Zoster Virus (VZV) edema of the eyelids and periorbital tissue, pain, Transmission: Person to Person Contact / photophobia, and blurred vision Droplet or Airborne Prevention: Contact Precautions Virus: Adenoviruses Shingles (also known as herpes zoster) Transmission: Direct Contact Symptoms: fluid-filled blisters, pain, and paraesthesia (numbness and tingling) Hemorrhagic Conjunctivitis Prevention: Airborne and Contact Precautions Symptoms: sudden onset, with redness, swelling, Virus: Varicella- Zoster Virus (VZV) and pain in one or both eyes Transmission: Person to Person Contact/ Droplet Prevention: Contact Precautions or Airborne Virus: Adenoviruses and Enteroviruses. Transmission: Direct / Indirect Contact German measles (rubella) Symptoms: fine, pinkish, flat rash Prevention: Droplet Precautions VIRAL INFECTIONS OF THE UPPER RESPI Virus: Rubella Virus Transmission: Droplet Spread or Direct Contact The Common Cold (Acute Viral Rhinitis, Acute Coryza) Measles (Hard Measles, Rubeola) Symptoms: coryza, sneezing, runny eyes, sore Symptoms: fever, conjunctivitis, cough, throat, chills, and malaise photosensitivity, koplik spots in the mouth, and red Prevention: Droplet Precaution blotchy skin rash. Virus: Rhinoviruses Prevention: Airborne Precautions Transmission: Respiratory Secretions or Direct Virus: Measles Virus (rubeola virus) Contact Transmission: Droplet Spread/ Direct Contact VIRAL INFECTIONS OF THE LOWER RESPI Monkeypox Symptoms: fever, headache, backache, Acute, Febrile, Viral Respiratory Disease lymphadenitis, malaise (fatigue), and a rash Symptoms: fever and one or more of the following Prevention: Airborne and Contact Precautions systemic reactions: chills, headache, general aching, Virus: Monkeypox Virus malaise, anorexia, and sometimes GI disturbances Transmission: Animal Bite/ Contact with an in infants. infected Animal’s Blood Prevention: Standard Precautions and Contact Precautions Smallpox Virus: parainfluenza viruses, RSV, adenovirus, Symptoms: fever, malaise, headache, prostration, rhinoviruses, certain coronaviruses, severe backache, skin rash, occasional abdominal coxsackieviruses, and echoviruses. pain, and vomiting Transmission: Direct Oral Contact/ Droplet Prevention: Airborne and Contact Precautions Virus: Two Strains of Variola: (a) variola minor HPS (Hantavirus Pulmonary Syndrome) and (b) variola major Symptoms: fever, myalgias, GI complaints, cough, Transmission: Person to person transmission difficulty breathing, and hypotension Prevention: Standard Precautions Warts Virus: Five Hantaviruses (Sin Nombre, Bayou, Symptoms: small, fleshly, grain bumps Black Greek Canal, New York-1 and Monongahela) Prevention: Contact Precautions Transmission: Inhalation of aerosolized rodent Virus: 70 types of human papillomaviruses (HPV) feces, urine, and saliva Transmission: Direct Contact Influenza (Flu) household Symptoms: fever, chills, headache, aches, and contact with HBV, an an infected pains throughout the body (most pronounced in the enveloped, person; back and legs), sore throat, cough, nasal drainage Type B circular dsDNA mother-to- Prevention: Droplet Precautions Hepatitis virus in the infant before Usually Virus: Influenza viruses types A, B, and C. (HBV genus or during has an infection Orthohepadnavi birth; injected insidious Transmission: Airborne Spread and Direct and serum rus, family drug use; (gradual) Contact hepatitis) Hepadnaviridae tattooing; onset ; the only DNA needlesticks Avian Influenza (Bird Flu) virus that and other Symptoms: fever, cough, sore throat, and muscle causes hepatitis types of healthcareass aches ociated Prevention: Droplet Precaution transmission Virus: Avian influenza virus type A Type C HCV, an Primarily Transmission: Contact with infected poultry and Hepatitis enveloped, parenterally Person to Person (HCV linear ssRNA transmitted Usually infection virus in the and rarely an and non-A, genus sexually insidious Severe Acute Respiratory Syndrome (SARS) non-B Hepacivirus, transmitted onset Symptoms: high fever, chills, headache, a general hepatitis) family feeling of discomfort, body aches, and sometimes Flaviviridae diarrhea. HDV or delta Exposure to virus, an infected blood Prevention: Standard, Airborne, Droplet, and enveloped, and body Contact Precautions Type D circular ssRNA fluids; Usually Virus: SARS-CoV Hepatitis viral satellite (a contaminated has an Transmission: Respiratory Droplets (delta defective RNA needles; abrupt hepatitis) virus) in the sexual onset genus transmission; VIRAL INFECTIONS OF THE GASTRO Deltavirus coinfection with HBV is Viral Gastroenteritis (Viral Enteritis, Viral necessary Diarrhea) HEV, a Fecal–oral spherical, transmission; Symptoms: nausea, vomiting, diarrhea, nonenveloped, primarily via abdominal pain, myalgia, headache, malaise, and Type E ssRNA virus in fecally Similar low-grade fever Hepatitis the genus contaminated to type A Prevention: Standard Precautions and Contact Calcivirus, drinking hepatitis family water; also Precautions Calciviridae from person Virus: enteric adenoviruses, astroviruses, to person caliciviruses, norovirus, rotaviruses HGV, a linear Transmission: Fecal Oral Route, Airborne, ssRNA virus in Can Foodborne, Waterborne, and shellfish transmission Type G the genus Parenteral cause Hepatitis Hepacivirus, chronic family hepatitis Flaviviridae Viral Hepatitis Symptoms: fever, fatigue, loss of appetite, nausea, VIRAL INFECTIONS OF GENITOURINARY vomiting, abdominal pain, dark urine, light- coloured stools, joint pain, and jaundice. ANOGENITAL HERPES VIRAL INFECTION (GENITAL HERPES) Characteristics: localized primary lesion, latency, NAME OF NAME AND TYPE TRANSMISSION DISEASE OF VIRUS and a tendency to localized recurrence Type A Fecal- oral Site in Women: cervix and vulva, with recurrent Hepatitis HAV, a transmission, disease affecting the vulva, perineal skin, legs, and (HAV nonenveloped, person to infection, linear ssRNA person, buttocks infectious virus in the infected food Abrupt Site in Men: penis and in the anus and rectum of hepatitis, genus handlers, onset those engaging in anal sex and Hepatovirus, fecally Symptoms: itching, tingling, and soreness, epidemic family contaminated followed by a small patch of redness and then a hepatitis) Picornaviridae foods and water group of small, painful blisters Sexual or Prevention: Standard Precautions and Contact VIRAL INFECTIONS OF CNS Precautions Virus: HSV-2 or HSV-1 LYMPHOCYTIC CHORIOMENINGITIS Transmission: direct sexual contact, or oral– Symptoms: fever, malaise, suppressed appetite, genital, oral–anal, or anal genital contact, mother- muscle aches, headache, nausea, vomiting, sore to-fetus or mother to-neonate during pregnancy throat, coughing, joint pain, chest pain, and salivary and birth gland pain Prevention: Standard Precaution GENITAL WARTS (GENITAL PAPILLOMATOSIS, Virus: Lymphocytic Choriomeningitis CONDYLOMA ACUMINATUM) Mammarenavirus Characteristics: tiny, soft, moist, pink or red Transmission: Infected rodents, primarily the swellings, which grow rapidly and may develop common house mice serve as reservoirs stalks. Rough surfaces give them the appearance of small cauliflowers. Can be malignant. POLIOMYELITIS Site in Women: vulva, vaginal wall, cervix, and Symptoms: Minor Illness with Fever, Malaise, skin surrounding the vaginal area Headache, Nausea, and Vomiting Site in Men: penis Prevention: Contact Precaution Symptoms: small, flesh-coloured or grey painless Virus: Polioviruses growths or lumps, itching or bleeding change to Transmission: person to person, primarily via the your normal flow of pee (for example, sideways) fecal–oral route; also by throat secretions Prevention: Standard Precautions and Contact Precautions RABIES Virus: Epstein–Barr virus (EBV), a.k.a. human Symptoms: Mental Depression, Restlessness, herpesvirus Headache, Fever, Malaise, Paralysis, Salivation, Transmission: direct contact, usually sexual; Spasms of Throat Muscles through breaks in skin or mucous membranes; or Prevention: Standard Precaution from mother to neonate during birth Virus: Rabies Virus Transmission: Bite of a rabid animal, which VIRAL INFECTIONS OF CIRCULATORY introduces virus-laden saliva. Airborne transmission from bats in caves also occurs. HIV INFECTION AND AIDS Symptoms: Fever, Rash, Headache, VIRAL MENINGITIS Lymphadenopathy, Pharyngitis, Myalgia (Muscle Symptoms : Sudden onset of febrile illness with Pain), Arthralgia (Joint Pain), Aseptic Meningitis, the signs and symptoms of meningeal Retro-orbital Pain, Weight Loss, Depression, GI involvements. A rash may develop. When caused by Distress, Night Sweats, and Oral or Genital Ulcers an enterovirus, GI and respiratory symptoms may Prevention: Standard and Transmission-Based occur. Precautions Prevention: Standard and Contact Precaution Virus: HIV (HIV-1 and HIV-2) Virus: Enteroviruses, or coxsackie viruses, Transmission: Direct Sexual Contact, sharing of arboviruses, measles virus, mumps virus, herpes contaminated needles and syringes by intravenous simplex viruses and VZVs, lymphocytic drug abusers; transfusion of contaminated blood choriomeningitis virus, and adenoviruses. and blood products; transplacental transfer from Transmission: vary with the specific etiologic mother to child; breast-feeding by HIV-infected agent mothers; transplantation of HIV-infected tissues or organs; and needlestick, scalpel, and broken glass VIRAL ENCEPHALITIS injuries Symptoms: headache, high fever, stupor, disorientation, coma, tremors, occasional MUMPS (Infectious Parotitis) convulsions, spastic paralysis Symptoms: Fever, Headache, Muscle aches, Prevention: Standard and Transmission-Based Tiredness, Loss of Appetite Precaution Prevention: Droplet Precaution Virus: St. Louis Encephalitis Virus Virus: Mumps Virus (genus Rubulavirus, family Transmission: Transfusion, Organ Transplant, Paramyxoviridae) Breast Milk, or Transplacental Transmission: Droplet Spread and Direct Contact with the Saliva of an Infected Person HOW DO VIRUSES CAUSE DISEASE?
Viruses multiply within host cells, and it is during
their escape from those cells—by either cell lysis or budding—that the host cells are destroyed. This cell destruction leads to most of the symptoms of the viral infection, which vary depending on the location of the infection.
Certain viruses cause only specific infections,
because viruses can infect only the cells bearing appropriate surface receptors, thus, viruses are specific as to the type of cell that they can infect.
HIV-AIDS virus destroys cells of the immune
system. This make the patient unable to fight various viral, bacterial, fungal, and parasitic pathogens.