CHEMICAL COORDINATION AND INTEGRATION

NEET
1. The blood calcium level is lowered by the deficiency of
[2008]
(A) Calcitonin (B) Parathormone
(C) Thyroxine (D) Both Calcitonin and Parathormone

2. In human adult females oxytocin

[2008]
(A) Causes strong uterine contractions during parturition (B) Is secreted by anterior pituitary
(C) Stimulates growth of mammary glands (D) Stimulates pituitary to secrete
vasopressin

3. Which of the following pairs of organs includes only the endocrine glands?
[2008]
(A) Adrenal and Ovary (B) Parathyroid and Adrenal
(C) Pancreas and Parathyroid (D) Thymus and Testes

4. A health disorder that results from the deficiency of thyroxine in adults and characterised by (i) a low
metabolic rate, (ii) increase in body weight and (iii) tendency to retain water in tissues is:
[2009]
(A) Simple goiter (B) Myxoedema (C) Cretinism (D)
Hypothyroidism

5. Select the correct matching of a hormone, its source and function.

[2010]

Hormone Source Function

(A) Vasopressin Posterior pituitary Increases loss of water through urine
(B) Norepinephrine Adrenal medulla Increases heart beat, rate of respiration and
alertness
(C) Glucagon Beta-cells of Islets Stimulates glycogenolysis
of langerhans
(D) Prolactin Posterior Pituitary Regulates growth of mammary glands and milk
formation in females
6. Toxic agents present in food which interfere with thyroxine synthesis lead to the development of
[2010]
(A) Thyrotoxicosis (B) Toxic goitre
(C) Cretinism (D) Simple goitre

7. Which one of the following pairs is wrongly matched while the remaining three are correct ?
[2011]
(A) Bryophyllum – Leaf buds (B) Agave – Bulbils
(C) Penicillium – Conidia (D) Water hyacinth – Runner

8. Match the source gland with its respective hormone as well as the function
[2011]

Source gland Hormone Function

Thyroid Thyroxine Regulates blood calcium level

Anterior pituitary Oxytocin Contraction of uterus muscles during child birth

Posterior pituitary Vasopressin Stimulates resorption of water in the distal tubules in the
 nephron

Corpus luteum Estrogen Supports pregnancy

(A) a (B) b (C) c (D) d

9. Given below is an incomplete table about certain hormones, their source glands and one major effect
of each on the body in humans. Identify the correct option for the three blanks A, B and C
[2011]

GLANDS SECRETION EFFECT ON BODY

A Oestrogen Maintenance of secondary sexual characters
Alpha cells of Islets of Langerhans B Raises blood sugar level
Anterior pituitary C Over secretion leads to gigantism
A B C
(A) Placenta Glucagon Calcitonin
(B) Ovary Glucagon Growth hormone
(C) Placenta Insulin Vasopressin
(D) Ovary Insulin Calcitonin

10. Which one of the following pairs of hormones are the examples of those that can easily pass through
the cell membrane of the target cell and bind to a receptor inside is (mostly in the nucleus)
[2012]
(A) Somatostatin, oxytocin (B) Cortisol, testosterone
(C) Insulin, glucagon (D) Thyroxin, Insulin

11. A pregnant female delivers a baby who suffers from stunted growth, mental retardation, low
intelligence quotient and abnormal skin.
[2013]
This is the result of :
(A) Deficiency of iodine in diet (B) Low secretion of growth hormone
(C) Cancer of the thyroid gland (D) Over secretion of pars distalis

12. Which of the following statements is correct in relation to the endocrine system ?
[2013]
(A) Adenohypophysis is under direct neural regulation of the hypothalamus
(B) Organs in the body like gastrointestinal tract, heart, kidney and liver do not produce any hormones
(C) Non-nutrient chemicals produced by the body in trace amount that act as intercellular messenger
are known as hormones
(D) Releasing and inhibitory hormones are produced by the pituitary gland

13. Select the answer which correctly matches the endocrine gland with the hormone it secretes and its
function/deficiency symptom :
[2013]
Endocrine gland Hormone Function/deficiency symptoms
(A) Anterior pituitary Oxytocin Stimulates uterus contraction during child
birth
(B) Posterior pituitary Growth Hormone (GH) Oversecretion stimulates abnormal growth
(C) Thyroid gland Thyroxine Lack of iodine in diet results in goitre
(D) Corpus luteum Testosterone stimulates spermatogenesis

14. Identify the hormone with its correct matching of source and function:
[2014]
 (A) Oxytocin - posterior pituitary, growth and maintenance of mammary glands.
(B) Melatonin - pineal gland, regulates the normal rhythm of sleepwake cycle.
(C) Progesterone - corpus-Iuteum, stimulation of growth and activities of female secondary sex
organs.
(D) atrial natriuretic factor- ventricular wall increases the blood pressure.

15. Fight - or - flight reaction cause activation of:

[2014]
(A) The parathyroid glands, leading to increased metabolic rate.
(B) The kidney, leading to suppression of renin angiotensin-aldosterone pathway.
(C) The adrenal medulla, leading to increased secretion of epinephrine and norepinephrene
(D) The pancreas leading to a reduction in the blood sugar levels.

16. Which one of the following hormones is not involved in sugar metabolism?
[2015]
(A) Glucagon (B) Cortisone (C) Aldosterone (D) Insulin
17. Which one of the following hormones though synthesized elsewhere, insole and released by the
master gland? [2015]
(A) Melanocyte shmulating hormone (B) Antidiuretic hormone
(C) Luteinizing hormone (D) Prolactin
18. Which of the following pairs of hormones are not antagonistic (having opposite effects) to each other?
[2016]
(A) Parathormone – Calcitonin (B) Insulin – Glucagon
(C) Aldosterone – Atrial Natriuretic Factor (D) Relaxin – Inhibin

19. Identify the correct statement on ‘inhibin’:

[2016]
(A) Inhibits the secretion of LH, FSH and Prolactin
(B) Is produced by granulosa cells in ovary and inhibits the secretion of FSH
(C) is produced by granulosa cells in ovary and inhibits the secretion of LH
(D) is produced by nurse cells in testes and inhibits the secretion of LH.

20. Identify the correct statement on ‘inhibin’:

[2016]
(A) Inhibits the secretion of LH, FSH and Prolactin
(B) Is produced by granulose cells in ovary and inhibits the secretion of FSH
(C) is produced by granulose cells in ovary and inhibits the secretion of LH
(D) is produced by nurse cells in testes and inhibits the secretion of LH.

21. Graves’ disease is caused due to

[2016]
(A) Hyposecretion of thyroid gland (B) Hypersecretion of thyroid gland
(C) Hyposecretion of adrenal gland (D) Hypersecretion of adrenal gland

22. Which of the following pairs of hormones are not antagonistic (having opposite effects) to each other?

[2016]
(A) Parathormone – Calcitonin (B) Insulin – Glucagon
(C) Aldosterone – Atrial Natriuretic Factor (D) Relaxin – Inhibin

23. The posterior pituitary gland is not a ‘true’ endocrine gland because
[2016]
(A) It is provided with a duct (B) It only stores and releases
hormones
(C) It is under the regulation of hypothalamus (D) It secretes enzymes
24. GnRH, a hypothalamic hormone, needed in reproduction, acts on :
[2017]
(A) Anterior pituitary gland and stimulates secretion of LH and oxytocin.
(B) Anterior pituitary gland and stimulates secretion of LH and FSH.
(C) Posterior pituitary gland and stimulates secretion of oxytocin and FSH
(D) Posterior pituitary gland and stimulates secretion of oxytocin and FSH.
25. A temporary endocrine gland in the human body is:
[2017]
(A) Pineal gland (B) Corpus cardiacum (C) Corpus luteum (D) Corpus
allatum

26. Hypersecretionof Growth Hormone in adults does not cause further 'increase in height because :
[2017]
(A) Growth Hormone becomes inactive in adults.
(B) Epiphyseal plates close after adolescence.
(C) Bones loose their sensitivity to Growth Hormone in adults.
(D) Muscle fibres do not grow in size after birth.
AIIMS
27. Secretion of which of the following is under neurosecretory nerve axons?
[1998]
(A) Pineal (B) Adrenal cortex (C) Anterior pituitary (D) Posterior
pituitary

28. Addison’s disease results from

[1998]
(A) Hyposecretion of adrenal (B) Hypertrophy of gonads
(C) Hyperactivity of cells of Leydig (D) None of these

29. Treatment with ‘Alloxan’ destroys

[1998]
(A) STH cells (B)  − cells of islets of langerhans
(C) Cells of sertoli (D) Cells of Leydig

30. Sella Turcica is found:-

[2001]
(A) In bones (B) In joints (C) Nearby pituitary (D) Nearby
thyroid

31. Which of the following match is correct?

[2007]
Hormone Effect
(A) Oxytocin Milk ejection hormone
(B) Glucagon Decreases blood sugar level
(C) Adrenaline Decreases heart rate
(D) Thyroxine Decreases BMR

32. Assertion: Aldosterone is a steroid hormone and is important in the control of sodium and potassium
ion concentration in mammals.
[2007]
Reason: It upgrades sodium ion concentration in the ECF by promoting reabsorption of sodium ions
from renal tubules and excretion of potassium ions in urine.
(A) If both assertion and reason are true and reason is the correct explanation of assertion
(B) If both assertion and reason are true but reason is not the correct explanation of assertion
 (C) If assertion is true but reason is false
(D) If both assertion and reason are false.

33. Which of the following statements regarding glucagon is false?

[2007]
(A) It is secreted by  − cells of Langerhans
(B) It acts antagonisitically to insulin
(C) It decreases blood sugar level
(D) The gland responsible for its secretion is heterocrine gland

34. What is the effect of GnRH produced by hypothalamus?

[2010]
(A) Stimulates the synthesis and secretion of androgens
(B) Stimulates secretion of milk in mammary glands
(C) Stimulates foetal ejection reflex
(D) Stimulates synthesis of carbohydrates from non – carbohydrates in live.

35. Assertion : Adrenaline is called an emergency hormone.

[2010]
Reason : It acts on the cells of skeletal, cardiac, smooth muscles, blood vessels and fat cells.
(A) If both assertion and reason are true and reason is the correct explanation of assertion
(B) If both assertion and reason are true but reason is not the correct explanation of assertion
(C) If assertion is true but reason is false
(D) If both assertion and reason are false.

36. Assertion : Insulin is antagonistic to glucagon.

[2010]
Reason : It is an anabolic hormone.
(A) If both assertion and reason are true and reason is the correct explanation of assertion
(B) If both assertion and reason are true but reason is not the correct explanation of assertion
(C) If assertion is true but reason is false
(D) If both assertion and reason are false.

37. Assertion: Hormone calcitonin has antagonistic effect to that of parathormone.

Reason: Calcitonin decreases blood calcium level while parathormone increases blood calcium level.
(A) If both assertion and reason are true and reason is the correct explanation of assertion
(B) If both assertion and reason are true but reason is not the correct explanation of assertion
(C) If assertion is true but reason is false
(D) If both assertion and reason are false.
38. Assertion : Less iodine intake causes goiter
[2012]
Reason : Less iodine in body decreases thyroxine secretion.
(A) If both assertion and reason are true and reason is the correct explanation of assertion
(B) If both assertion and reason are true but reason is not the correct explanation of assertion
(C) If assertion is true but reason is false
(D) If both assertion and reason are false.

39. Assertion: Oxytocin is also known as Anti – diuretic hormone (ADH).

[2012]
Reason: Oxytocin can cause an increase in the renal reabsorption of water.
(A) If both assertion and reason are true and reason is the correct explanation of assertion
(B) If both assertion and reason are true but reason is not the correct explanation of assertion
(C) If assertion is true but reason is false
(D) If both assertion and reason are false.
40. Match the source gland with its respective hormone and function and select the correct option
[2013]
A - Source gland, B – Hormone, C – Function
(A) A – Anterior pituitary, B – Oxytocin, C – Contraction of uterine muscles
(B) A - Anterior pituitary, B – Vasopressin, C – Induces reabsorption of water in nephron
(C) A – Thymus, B – Thymosin, C – Proliferation of T – lymnphocytes
(D) A -  - cells of islets of Langerhans, B – Glucagon, C - Uptake of glucose into the cell.

JIPMER
41. Hormones of hypothalamus are called
[2000]
(A) Angiotensins (B) Trophic hormones
(C) Growth hormones (D) Regulatory hormones

42. Hormones of hypothalamus are called

[2000]
(A) Angiotensins (B) Trophic hormones
(C) Growth hormones (D) Regulatory hormones

43. Which of the following glands is associated with the consumption of iodised salt?
[2001]
(A) Ovary (B) Pituitary (C) Thymus (D) Thyroid

44. Daily rhythms are usually associated with

[2001]
(A) Hypothalamus (B) Thymus (C) Pituitary (D) Pineal

45. Posterior pituitary contains and releases

[2002]
(A) Oxytocin, prolactin and GH (B) Oxytocin and estrogen
(C) Vasopressin and estrogen (D) Oxytocin and vasopressin

46. Broadly defined, a hormone is a molecule that:

[2003]
(A) Has the same chemical activity in a variety of organisms
(B) Alters the activity of certain nonadjacent cells
(C) Influences development
(D) Moves through the blood stream

47. Some important hormones involved in carbohydrate metabolism are

[2003]
(A) Insulin, glucagon, norepinephrine and neotinin (B) Insulin, glucagon. Gluccortiocoids
and calcitonin
(C) Insulin, glucagon, epinephrine and glucocorticoids (D) Insulin, glucagon, epinephrine and
parathormone

48. Osmoregulation is the function of

[2005]
(A) Prolactin (B) Oxytocin
(C) Vasopressin (D) None of these

49. Testosterone is secreted by

[2005]
(A) Letdig cells (B) Spermatozoa
(C) Sertoli cells (D) Spermatids
50. Water reabsorption in kidney is controlled by:
[2005]
(A) GH (B) ADH
(C) Aldosterone (D) Oxytocin

51. Which of the following is the largest gland in an adult man?

[2009]
(A) Thymus (B) Liver (C) Thyroid (D) Pancreas

52. During emergency which of the following hormone is secreted?

[2009]
(A) Aldosterone (B) Thyroxine (C) Adrenalin (D) Calcitonin

53. LH and FSH are collectively called

[2009]
(A) Oxytocin (B) Somatotropins (C) Luteotropic (D)
Gonadotropins

54. The function of pineal body is to

[2009]
(A) Lighten the skin colours (B) Control sexual behavior
(C) Regulates the period of puberty (D) All of the above

55. Follicle stimulating hormone organ in

[2010]
(A) Anterior lobe of pituitary (B) Hypothalamus
(C) Gonads (D) Posterior lobe of pituitary

56. Calcitonin is a thyroid hormone which

[2011]
(A) Elevates potassium level in blood (B) Lowers calcium level in blood
(C) Elevates calcium level in blood (D) Has no effect on calcium

57. Which of the following is mismatched?

[2011]
(A) Vitamin - K – Beri – beri (B) Vitamin - D – Rickets
(C) Vitamin - C – Scurvy (D) Vitamin - A – Xerophthalmia

58. Gigantism and acromegaly are due to

[2012]
(A) Hypothyroidism (B) Hyperthyroidism
(C) Hypopituitarism (D) Hyperpituitarism
59. Endemic goiter is a state of
[2013]
(A) Normal thyroid function (B) Moderate thyroid function
(C) Increased thyroid function (D) Decreased thyroid function
60. Hormone responsible for the secretion of milk after parturition is
[2013]
(A) ACTH (B) LH (C) ICSH (D) Prolactin
61. Steroid hormones work as
[2014]
(A) They enter into target cells and binds with specific receptor and ativate4s specific genes to form
protein
 (B) They binds to cell membrane
(C) They catalyse formation of cAMP
(D) None of the above
62. Adrenaline and noradrenaline are hormones that act as
[2014]
(A) Energy producing agents (B) Food storage materials
(C) Neurotransmitters (D) Energy storing substances

63. Which hormone produces calorigenic effect?

[2015]
(A) Thyroxine (B) FSH (C) Insulin (D) All of these