S-LCY-B33

High Performance Liquid Chromatograph

i-Series
Living LC
 Dual-Temperature Dual-Temperature
Control with TC-Optics
Control
andwith
FlowTC-Optics
Cells and Flow Cells

Excellent Baseline
Excellent
Stability
Baseline Stability

°C °C In addition to the temperature

In addition to the temperature
mAU mAU
Room temperature Room temperature 35 35
control function for flow
control
cells, function
the for flow cells, the

40 40 i-Series employs new temperature

i-Series employs new temperature
30 30
control technology for control
detector
technology for detector
30 30
25 Non-Shimadzu system 25 optical systems,
Non-Shimadzu system knownoptical
as systems, known as
(UV detector) (UV detector)
Fluctuation range: TC-Optics (Temperature
Fluctuation range: TC-Optics (Temperature
20 20
Approx. 27.5 mAU 20 Approx. 27.5 mAU
20 Controlled Optics). ThisControlled
ensures a Optics). This ensures a

10 10
more stable baseline that
moreis less
stable baseline that is less

LC-2050C (UV)
susceptible
LC-2050C (UV)
to room temperature
susceptible to room temperature
0 0 Fluctuation range: Fluctuationand
variation range:
increasedvariation
precisionand increased precision
Approx. 1.3 mAU Approx. 1.3 mAU
0 50 100 0150 50
200 100
250 150
300 200min 250 300 min during verification testing
during
andverification testing and
quantitative testing of quantitative
trace testing of trace
components. components.

Ultra-Low Carryover
Ultra-Low
Performance
Carryover
Enables
Performance
High-Sensitivity
Enables Analysis
High-Sensitivity Analysis

Improved Reliability
Improved of Reliability
Trace Component
of TraceAnalysis
Component Analysis

Shimadzu’s proprietaryShimadzu’s
flow channel
proprietary
design, parts,
flow and
channel
materials
design,
reduce
parts,the
andcarryover
materialseffects
reduceofthe
sample
carryover
residue
effects
to of sample residue to
almost zero. Ultra-low carryover
almost zero.
performance
Ultra-low carryover
has been performance
improved to 0.0025%
has been(chlorhexidine,
improved to 0.0025%
assigned(chlorhexidine,
conditions), assigned conditions),
thereby providing highly
thereby
preciseproviding
quantitative
highly
performance
precise quantitative
when analyzing
performance
complex
when
samples.
analyzing complex samples.

mAU mAU
µAU µAU

1500 1500
100 100

1250 1250
80 80

1000 1000
60 60

750 750
40 40

500 500

20 20
250 250
0 0

0 0 0.9 1.0 1.1 0.9min 1.0 1.1 min

0.85 0.90 0.95 1.00 1.05

0.85 1.10
0.90 1.15
0.95 min
1.00 1.05 1.10 1.15 min

Chromatogram after injecting

Chromatogram
chlorhexidine
after injecting chlorhexidine Chromatogram after injecting
Chromatogram
a blank sample
after injecting a blank sample
(mobile phase) (mobile phase)

14 14
Data management
Data management

ompliant with
Compliant
ER/ES Guidelines
with ER/ESand
Guidelines
Data Integrity
and Data Integrity

bSolutions has a variety

LabSolutions
of functions
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ensure of
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functionswith
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with
andFDA
Japanese
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of Health,
Japanese Ministry of Health,
bour and Welfare guidelines
Labour and
on electronic
Welfare guidelines
records and
on electronic
electronic records
signatures.
and LabSolutions
electronic signatures.
also includes
LabSolutions
functionsalso includes functions
at address and support
thatdata
address
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and support data integrity.

entralized Management
Centralized Management
of Data and of Data and
ser Information
User Information

ta and user information

Dataare
andmanaged
user information
on a database
are managed
with on a database with
Method creation Method creation
Method change AnalysisMethodRe-analysis
change Analysis
Compile data Re-analysis Compile data
trictions on data filerestrictions
deletion andon adata
version
file deletion
number and a version number
nagement function management
that ensures safe
function
storage.
thatFurther
ensures safe
- storage. Further -
re, fine-grained division
more,offine-grained
operational division
restrictions
of operational
allows restrictions allows
timum user management
optimum
based
user
onmanagement
role, such as based
systemon role, such as system
ministrator, analysis administrator,
operator, etc. analysis
LabSolutions
operator,
records
etc. LabSolutions records
An “audit trail” that records
Anall
“audit
operations
trail” that records all operations
e access status of thethe
system,
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status oftothe
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and methods,
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erations performed operations
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anges to system settings,
changes
etc.to system settings, etc.

eview of Operation
Review of
Logs
Operation Logs

eport set function compiles

A reportanalytical
set function
conditions
compilesoranalytical conditions or
Batch reports Batch reports
analytical
alytical results/conditions results/conditions
for sets of analysis (batch
for sets of analysis (batch Other reports Other reports

alysis) and also compiles

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mpletion of analysis.completion
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lects information, prevents
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prevents operational errors. Audit trails Audit trails

eamless Integration
SeamlessofIntegration
Testing andofAnalysis
Testing and Analysis

bSolutions i-QLinks LabSolutions

™
can create test
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incorporate
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d other analytical instruments,
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manageof quality
the progress
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status of quality testing.

15 15
 i-Series

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© Shimadzu (Asia Pacific) Pte Ltd., 2021 First Edition: May 2021
© Shimadzu Corporation, 2021 First Edition: November 2020 3655-01105-PDFNS, C196-E098A