ANTIBIOTIC

SENSITIVITY CHART
Created by James McCormack, BSc(Pharm), Pharm D and Fawziah Lalji, BSc(Pharm), PharmD, FCSHP
with help from Michael Legal and Tim Lau
Faculty of PharmaceuGcal Sciences, University of BriGsh Columbia, Vancouver, BC
Gram PosiGve Cocci Gram NegaGve Bacilli Gram NegaGve Coccobacilli Anaerobes Atypicals
Streptococci Staphylococci

Streptococci Non-beta-lactamase producing SPACE

Bacteria Staph Staph Community Hospital Beta-lactamase producing SerraGa marcescens,
ESBL Mycoplasma
Escherichia coli, (Extended spectrum beta- Below the
(pneumoniae/ Enterococci epidermidis acquired acquired Escherichia coli, Proteus mirabilis, Pseudomonas Above the diaphragm Clostridium pneumoniae, Legionella Chlamydia
aureus Methicillin Methicillin
Klebsiella pneumoniae, Acinetobacter sp.,
lactamase producing) Neisseria meningiGdis Neisseria gonorrhea diaphragm
pyogenes/ (Group D strep) (coagulase Klebsiella pneumoniae, Escherichia coli, aeruginosa (Peptostreptococcus) difficile Chlamydophilia pneumophilia trachomaGs
Methicillin sensiGve resistant resistant Haemophilus influenzae Citrobacter sp., (Bacteroides sp)
viridans) negaGve) Haemophilus influenzae Klebsiella pneumoniae spp
Enterobacter sp.

Brain, oral, respiratory tract, Intraabdominal, Intraabdominal, pelvic Pelvic inflammatory

LocaGon heart, skin urinary tract
Skin, prostheGcs Oral, respiratory tract, heart, skin, bones/joint Brain, respiratory tract, intraabdominal, urinary tract Brain Pelvic inflammatory disease/STI Oral, respiratory tract inflammatory disease
Intraabdominal Respiratory tract
disease/STI

Pencillin V/G Pencillin G-IV Pencillin V/G

Amoxicillin/ampicillin Amoxicillin/ampicillin Ampicillin-IV Amoxicillin/ampicillin
Penicillins Cloxacillin
Amoxicillin-clavulanate Amoxicillin-clavulanate Amoxicillin-clavulanate Amoxicillin-clavulanate
Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam Piperacillin-tazobactam
Cefazolin/cephalexin Cefazolin/cephalexin Cefazolin/cephalexin Cefazolin/cephalexin
Cefuroxime Cefuroxime Cefuroxime Cefuroxime
CefoxiGn/cefotetan CefoxiGn/cefotetan CefoxiGn/cefotetan CefoxiGn/cefotetan
Cephalosporins CeZriaxone/cefotaxime CeZriaxone/cefotaxime CeZriaxone/cefotaxime CeZriaxone/cefotaxime
Cefixime Cefixime Cefixime
CeZazidime CeZazidime
Cefipime Cefipime Cefipime Cefipime Cefipime
Meropenem/imipenem Meropenem/imipenem Meropenem/imipenem Meropenem/imipenem
Carbapenems Ertapenem Ertapenem Ertapenem Ertapenem
Erythromycin Erythromycin Erythromycin
Macrolides
Clarithromycin/azithromycin Clarithromycin/azithromycin Clarithromycin/azithromycin JUST H.flu JUST azithromycin Clarithromycin/azithromycin JUST azithromycin
Tetracycline/doxycycline Tetracycline/doxycycline Tetracycline/doxycycline JUST H.flu Tetracycline/doxycycline Tetracycline/doxycycline
Tetracyclines
Tigecycline Tigecycline Tigecycline
Ciprofloxacin/norfloxacin BUT JUST bladder infecGons for norfloxacin Ciprofloxacin
Fluoroquinolones
Levofloxacin/moxifloxacin Levofloxacin/moxifloxacin Levofloxacin/moxifloxacin JUST Moxifloxacin Levofloxacin/moxifloxacin
Aminoglycosides/polymyxin Gentamicin/tobramycin/amikacin/colisGn
Lincosamides Clindamycin Clindamycin Clindamycin
GlycopepGdes/oxazolidinones Vancomycin/linezolid/daptomycin Vancomycin/linezolid/ daptomycin Vancomycin oral
Trimethoprim-Sulfamethoxazole Trimethoprim-sulfamethoxazole Trimethoprim-sulfamethoxazole
Chloramphenicol Chloramphenicol Chloramphenicol Chloramphenicol
Metronidazole Metronidazole
Nitrofurantoin/fosfomycin Nitrofurantoin/fosfomycin
Nitrofurantoin/fosfomycin Nitrofurantoin/fosfomycin
(JUST BLADDER INFECTIONS) JUST E.faecalis
Rifampin Rifampin Rifampin
Fidaxomicin Fidaxomicin
Cloxacillin and clindamycin typically have less than 40% ac6vity for S.epidermidis, thus usage depends on local suscep6bility data
Enterococci has two main species - Enterococcus faecalis and Enterococcus faecium - the an6bio6cs listed work well for E.faecalis, but have limited ac6vity for E.faecium
Cephalosporins have in-vitro ac6vity for SPACE organisms but induce produc6on of beta-lactamases
Tigecycline has no ac6vity for Pseudomonas aeruginosa, but for Acinetobacter it depends on local suscep6bility data; Tigecycline has ac6vity for SPACE organisms, but for Proteus spp it depends on local suscep6bility data
December 2015