PRIMARY LYMPHOMA OF BONE

IN A 9 YEARS OLD GIRL

Santa Ulina, Bidasari Lubis, Olga R Siregar

Department of Child Health,Faculty of Medicine University of

Sumatera Utara, Haji Adam Malik General Hospital, Medan
BACKGROUND
• Primary non-Hodgkin’s lymphoma of bone, often more simply referred to
as primary lymphoma of bone (PLB), is a rare presentation of non-
Hodgkin’s lymphoma in children.
• There is misdiagnosis of primary bone lymphoma in children because an
atypical main complaint.
• Most reports with complaints not being able to walk and come to
orthopedic division

OBJECTIVES
The aim of this case report is to report a case of primary lymphoma of bone
in 9 years old girl.
 PROBLEM DESCRIPTION
● EGM, a girl, 9 years 23 days, in
January 2019 she diagnose with
Beta-Talasemia.
● February 2019, the patient feels
discomfort and pain in her left
leg.
● June 2019, working together with
orthopedic department made a joint
conference to solve about the chief
complaint about both feet.
● July 2019 did a biopsy and the
results showed NHL malignant
smear.

Macroscopic :
One drop of reddish color aspirate
Microscopic :
Relatively hypercellular cell
Pleomorphic enlarged nucleus
Some of them are oval-shaped, round-shaped, irregular,
angled, notched
 1 2

1. Lymphoma o / t bone with compression fractures in some of the

thoracolumbar vertebrae
2. Extensive lytic lesions along the os. tibia and fibula with
pathological fractures in the proximal tibia and fibula.
multiple fractures distal to the femur with lytic lesions in the os
femoral.
3. Extensive lytic lesions along osteo tibia.
multiple proximal fractures of the tibia, fibula and condylus 3
femur.
CONCLUSION
Patients with primary lymphoma of bone often misdiagnosis because clinical
symptoms are not typical.