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NCM-114J
Recommend that
patient take a warm Administered
bath or shower upon medication
arising or at bedtime. appropriately
Apply warm, moist
compresses to affected
joints several times a Established
day. Monitor water positive self-
temperature of image.
compress, baths, and
so on. Heat
promotes muscle relax Discussed and
ation and mobility, provided safety
decreases pain, and needs such as
relieves morning raised chairs
stiffness. Sensitivity to and toilet seat,
heat may be use of handrails
in shower and
diminished and dermal
toilet, proper
injury may occur.
use of mobility
Encourage aids.
activity/exercise as
independence.
equivalent to RA
heritability, was
investigated in a study
of monozygotic and
dizygotic twins.
-Clinical manifestations
of RA vary, usually Lecture discussion
reflecting the stage and
severity of tge disease:
misalignment resulting
in swelling.
*Rheumatoid nodules.
Rheumatoid nodules
may be noted in
patients with more
advanced RA, and they
are nontender and
movable in the
subcutaneous tissue.
4. Complication
-Rheumatoid arthritis
medications can have
dangerous and perhaps
fatal side effects.
Suppression of the
bone marrow.
Immunosuppressants
used incorrectly can
cause bone marrow
suppression.
Anemia.
Immunosuppressive
drugs like
methotrexate and
cyclophosphamide are
extremely dangerous
and can cause anemia.
Disturbances in the
gastrointestinal tract.
Gastric inflammation
and ulceration are
possible side effects of
several NSAIDs.
5. Available treatment
-The drugs used in
each phase of
rheumatoid arthritis
include:
Early Rheumatoid
Arthritis
*NSAIDs. COX-2
medications block the
enzyme involved in
inflammation while
leaving intact the
enzyme involved in
protecting the stomach
lining.
*Methotrexate.
Methotrexate is
currently the standard
treatment of RA
because of its success
in preventing both joint
destruction and long-
term disability.
*Analgesics. Additional
analgesia may be
prescribed for periods
of extreme pain.
Moderate, Erosive
Rheumatoid Arthritis
*Cyclosporine. Neoral,
an immunosuppressant
is added to enhance
the disease modifying
effect of methotrexate.
Persistent, Erosive
Rheumatoid Arthritis
*Corticosteroids.
Systemic
corticosteroids are
used when the patient
has unremitting
inflammation and pain
or needs a “bridging”
medication while
waiting for slower
DMARDs to begin
taking effect.
Advanced, Unremitting
Rheumatoid Arthritis
*Immunosuppressants
. Immunosuppressive
agents are prescribed
because of their ability
to affect the production
of antibodies at the
cellular level.
*Antidepressants. For
most patients with RA,
depression and sleep
deprivation may
require the short-term
use of low-dose
antidepressants such as
amitriptyline,
paroxetine, or
sertraline, to
reestablish an
adequate sleep pattern
and to manage chronic
pain.
6. Therapy
For persistent, erosive RA,
reconstructive surgery is
often used.
*Reconstructive surgery.
Reconstructive surgery is
indicated when pain cannot
be relieved by conservative
measures and the threat of
loss of independence is
eminent.
*Synovectomy.
Synovectomy is the
excision of the synovial
membrane.
*Tenorrhaphy.
Tenorrhaphy is the suturing
of a tendon.
*Arthrodesis. Arthrodesis
is the surgical fusion of the
joint.
*Arthroplasty. Arthroplasty
is the surgical repair and
replacement of the joint.
7. Mom-pharmacological
management
*Exercises for
conditioning and
maintaining strength
and flexibility
*Local therapy
including moist hot
packs or cold following
trauma
*Orthopedic surgery to
repair structural
damage that may lead
to disability over the
long term