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  • Pengenceran Serbuk: Dexametason 50 MG SL Ad 500 MG 500 MG - 50 MG 450 MG

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    AGATHA RIA BUDIYANA
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    This document summarizes the steps to dilute and prepare powder and capsule formulations for several medications. It describes: 1) Diluting dexamethasone and codeine powders to concentrations below 50mg by adding lactose powder as a diluent. 2) Calculating the amount of chlorpromazine powder needed to achieve the correct daily dose for a 14 year old patient, which is determined to be 305.17mg. 3) Filling capsules with 200mg of aminophylline to achieve a total dose of 2000mg by dividing tablets into capsules of 166.67mg each and making up the remainder with lactose filler.

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    PENGENCERAN SERBUK

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    This document summarizes the steps to dilute and prepare powder and capsule formulations for several medications. It describes: 1) Diluting dexamethasone and codeine powders to concentrations below 50mg by adding lactose powder as a diluent. 2) Calculating the amount of chlorpromazine powder needed to achieve the correct daily dose for a 14 year old patient, which is determined to be 305.17mg. 3) Filling capsules with 200mg of aminophylline to achieve a total dose of 2000mg by dividing tablets into capsules of 166.67mg each and making up the remainder with lactose filler.

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    35 views4 pages

    Pengenceran Serbuk: Dexametason 50 MG SL Ad 500 MG 500 MG - 50 MG 450 MG

    Uploaded by

    AGATHA RIA BUDIYANA
    This document summarizes the steps to dilute and prepare powder and capsule formulations for several medications. It describes: 1) Diluting dexamethasone and codeine powders to concentrations below 50mg by adding lactose powder as a diluent. 2) Calculating the amount of chlorpromazine powder needed to achieve the correct daily dose for a 14 year old patient, which is determined to be 305.17mg. 3) Filling capsules with 200mg of aminophylline to achieve a total dose of 2000mg by dividing tablets into capsules of 166.67mg each and making up the remainder with lactose filler.

    Copyright:

    © All Rights Reserved
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    of 4

    PENGENCERAN SERBUK

    R/ Dexametason 0,5 mg x 6 = 3 mg < 50 mg  pengenceran

    Codein 0,003 gram = 3 mg x 6 = 18 mg < 50 mg  pengenceran

    m.f.pulv.dtd. No VI

    S.b.dd.I.pulv

    Pengenceran Dexametason

    1. Pengenceran pertama

    Dexametason = 50 mg

    SL ad 500 mg

    = 500 mg – 50 mg

    = 450 mg

    Penimbangan = 3 mg/50 mg x 500 mg = 30 mg < 50 mg (pengenceran bertingkat)

    2. Pengenceran kedua

     50 mg / 500 mg x 50 mg = 5 mg (Dexamethason)

    Pengenceran :

    Dexametason = 50 mg

    SL = ad 500 mg

     Penimbangan = 3 mg/5 mg x 500 mg = 300 mg > 50 mg

    Pengenceran Codein

    Codein 0,003 gram = 3 mg x 6 = 18 mg < 50 mg

    Codein = 50 mg

    Carmin = 50 mg

    SL ad 500 mg

    SL = 500 mg – (50 mg + 50 mg)

    = 400 mg

    Penimbangan = 18 mg / 50 mg x 500 mg = 180 mg > 50 mg


    PENIMBANGAN TABLET

    4 MG 8 MG

    R/ MP No. V  kecil

    m.f.pulv

    S.t.d.d. 1 pulv

    R/ Chlorpromazin HCl 2,5 gram  305,17 mg

    m.f.pulv. No. VII (no dtd)

    S.t.dd. I. Pulv

    Pro : Sinta (14 tahun)

    DM CPZ = 250 mg / 1000 mg

    Penimbangan CPZ = 2,5 gram

    Perhitungan DM CPZ HCl usia 14 th

    1xp = 14/20 x 250 mg = 175 mg

    1 hari = 14/20 x 1000 mg = 700 mg

    1 bungkus mgd CPZ = 2500 mg/7 = 357,14 mg

    PMR :

    1xp = 357,14 mg

    1 hari = 3 x 357,14 mg

    = 1071,42 mg

    % DT

    1xp = 357,14 mg/175 mg x 100% = 204,8 %

    1 hari = 1071,42 mg/700 mg x 100% = 153,06%

    R/, OD  PENURUNAN 25%

    25%/204,8% X 2500 mg = 305,17 mg

    1 bungkus mgd CPZ = 305,17/7 = 43,59 mg

    PMR :

    1xp : 43,59 mg

    1 hari : 3 x 43,59 mg

    : 130,77 mg

    % DT :
    1xp = 43,59 mg /175 mg x 100% = 24,9 %

    1 hari = 130,77 mg/700 mg x 100% = 18,68%

    R/, TOD, lanjut ke penimbangan

    Chlorpromazin HCl 2,5 gram  305,17 mg

    Sedia CPZ dlm tablet 25 mg 100 mg

    100 mg x 3 tab = 300 mg

    25 mg x 1 tab = 25 mg

    ----------------------------------- +

    = 325 mg  pengenceran

    Ambil tab  gerus  ditimbang

    CPZ Tab 100 mg  175 mg

    CPZ Tab 25 mg  75 mg

     3 x 175 mg = 525 mg
     1 x 75 mg = 75 mg
     TOTAL = 600 mg

     305,17 mg/325 mg x 600 mg = 563,39 mg

    PERHITUNGAN KAPSUL

    No 3 150 mg

    No 2 200 mg

    No 1 300 mg

    No 0 500 mg

    No 00 700 mg

    No 000 1000 mg

    R/ Aminophillinum 200 mg No X  200 mg x 10 = 2000 mg

    m.f.pulv. da in caps. No XV (no dtd)

    S.t.d.d.I.caps

    Pro : Ana (4 tahun)


    Sediaan : Aminophillin 100 ng dan 200 mg

    1 tab 200 mg = 250 mg

     10 x 250 mg = 2500 mg/15 (nomero)

    = 166,67 mg / kapsul

    No 3 150 mg

    No 2 200 mg

    No 1 300 mg

    No 0 500 mg

    No 00 700 mg

    No 000 1000 mg

    Selisih  SL

    200 mg – 166,67 mg = 33,33 mg / kapsul

    33,33 mg x 15 (nomero) = 499,95 mg

    = 500 mg (SL)

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