Professional Documents
Culture Documents
The laboratory information management system (LIMS) is designed to help process information in
medical research to improve the efficiency of the department's services and laboratory operations by reducing
manual tasks and procedures. For example, a LIMS records information automatically which saves time and
reduces typographical error. This is commonly used in conjunction with laboratory information systems (LIS)
in the medical and pharmaceutical industries.
According to Gartner's 2016 Hype Cycle for Life Sciences, most of the top pharmaceutical laboratories
use LIMS. The system is also useful for biobanks and genomic testing centers and laboratories that study
drugs and develop formulations. However, the health care institution must consider the data capture process,
storage, and retrieval in selecting the solutions provider because some are more suitable than others
(Reisenwitz, 2017).
Laboratory Standards
To help promote laboratory safety, the Occupational Exposure to Hazardous Chemicals in Laboratories
Standard (29 CFR 1910.1450) was released in the United States by the Occupational Safety and Health
Administration (OSHA) in 2011.
Some Important provisions from the standard are cited below:
Laboratory is a workplace where hazardous chemicals are used. It is also a facility that stores small quantities
of hazardous chemicals which are not intended for production use. On the other hand, the laboratory use of
hazardous chemicals should meet the conditions listed below:
• The manipulations of chemicals should be on "laboratory scale” only and can be handled by one
person.
• There is the use of multiple chemicals and procedures.
• The procedures should not simulate any production process.
• Protective laboratory tools are available and proper practices are followed to minimize potential
exposure to harmful chemicals.
• Any hazardous use of chemicals which does not meet this definition is regulated under other standards.
Examples are
✓ chemicals used in the maintenance of the laboratory building,
✓ production for commercial sale,
✓ and testing of a product for quality control.
A Chemical Hygiene Plan (CHP) which discusses all aspects of the laboratory standards should be
formulated if the standards apply. The employer must implement the provisions which address the proper
purchase, storage, handling, and disposal of the chemicals used in the facility.
The primary elements of a CHP include the following:
1. establishment of standard operating procedures (SOP) to minimize exposure to chemicals and
dissemination of information on the requirements for personal protective equipment. Waste
disposal procedures, and engineering controls;
2. monitoring of the work environment to provide the action and medical attention required for
some chemicals;
3. statement of plan on how to obtain free medical care for work-related exposures; and
4. designation of personnel who will handle CHP-related activities such as handling data sheets,
organizing trainings, monitoring adaption, and revising CHP if deemed necessary
LIMS Application
Patient Registration
When a patient arrives at the hospital, the admission clerk will take some basic information and will guide him
or her to a registration window.
Billing
The process of generating SOAs (statement of accounts) or billing statements of in-patients, out-patients, and
emergencies are the same. In the following example, an in-patient's billing statement is used.
Contract Management
Most LIMS allow the laboratory professionals to manage the billing and payment aspects of their activities and
to create statistical and billing reports on a par with the laboratory and management needs. They provide
parameters for a flexible price schedule and enable heightened attention on customer needs. They automate
billing processing, hasten collections, and offer marketing tools which reduce the time spent on standard flow
and allow billing and accounting personnel to focus on improving collection of problematic accounts (Infomed,
2017).
In addition, the common features of LIMS for invoicing and contract management include:
• customer customizable invoices including history analysis of balance and charges, history balance,
detailed services, and participation when in insurance coverage, discounts, among others;
• different electronic formats for invoices to allow interfacing with customer electronic systems;
• customizable information completion reports for customers;
• managerial reports which display laboratory billing status for payer groups including projected return
values for each payer group:
• ability to change the insurance organization of a patient per visit;
• ability to select which tests are covered by insurance and which have automatic modification of the
prices accordingly;
• supervision of financial data management of the senders;
• reminder for amounts due from past visits;
• immediate access to the billing card of each patient;
• and consistency with international laws.
Accounts Receivables
Through the integration of the LIMS, the personnel in charge of managing accounts receivables can easily
extract information which was already available from the invoicing and contract management procedures.
Additionally, the LIMS can
Quality Control
Diagnostic tests executed inside the clinical laboratory may yield two kinds of results, a patient result
or a quality control (QC) result. The result can be quantitative (in numbers), or qualitative (positive or negative)
or semi-quantitative (limited to a few different values). QC results are used to verify whether or not the
instrument is working within prescribed parameters. Based on the said results, reliability of a patient's test
results will be determined (Bio-Rad Laboratories, 2008).
LIMS' functions enable users to set standards about the relevant range of patient test results or to
extract test result information for the purpose of quality assurance. Outliers and deviations can be flagged,
and appropriate warning signals can notify users about issues which might involve the quality of the samples
or the equipment currently in use.
Evolution of CIS
Decades ago, the requirements for an electronic medical information system were restricted by the
availability of equipment. A good database schema combined with a functional user interface was deemed
adequate. In the 1970s, available cardiology information systems originated from mainframe environments,
whose technical specifics would be considered ridiculous in today's context.
In the 1980s, modular systems that emphasized the use of real-time applications and mini computers
became the trend (Turney & Kohls, 1997). Over the years, the trend for smaller computers remained, but the
introduction of the internet became a turning point that shifted the focus of most systems towards creating
networks and facilitating integration Cardiology information systems nowadays have unique features that
enable remote access and easy retrieval. Some systems have also attempted to integrate radiology
information systems (RIS) to involve more administrative processes and go beyond storage purposes
Benefits of CIS
Different CIS, coming from different sellers, vary in their available features. However, the following are the
most common benefits
1. Ease of Access while Maintaining Data Security
CIS consolidates multiple types of patient cardiology information, thus eliminating the need for
doctors to request different imaging results from different departments
3. Enhanced Comparability
CIS is an essential repository of cardiology imagery results, thereby, retrieval of past data is
convenient. This comparability enables health care professionals to make more informed decisions on
their patient's treatment.
Functionalities of CIS
1. Editing, Viewing, and Storing Multi-Modal Cardiology Data - With the help of CIS, different types
of data, including those of computed tomography (CT), cardiac ultrasound (echocardiography).
magnetic resonance imaging (MRI), nuclear imaging (PET and SPECT), and angiography may be
managed on a single platform.
2. Remote Access -The use of networks and integrated information systems, coupled with the availability
of the internet and tablets and smart phones, offers flexibility to CIS.
3. Visualization and Reporting Capabilities - Two of the main benefits of CIS are the case and the
consistency of reporting. As a result, virtual real-time information retrieval is possible anytime and
anywhere with just a couple of clicks.
4. EHR Integration - CIS may be integrated with existing electronic health record systems, this results in
the enhancement of the quality of services of the health professionals by offering a more
comprehensive view of the patient care spectrum.
Functions of RIS
Rouse (2017) describes the following functions of a RIS:
• Patient Management-The system tracks the patient's entire workflow within the radiology department.
It can add images and generate reports to EHRs for easy retrieval and viewing by the authorized
radiology staff.
• Scheduling-The system allows staff to schedule appointments for in-patients and out-patients
• Patient Tracking - Patient tracking means tracing the patient's radiology history starting from
admission to discharge and coordinating it with his or her past, present, and future appointments
• Results reporting - Results reporting is possible through the statistical reports generated by RIS. The
reports may be done for a single patient or a group of patients, as well as for specific
procedures, depending on the needs
• Image tracking -RIS was traditionally used to track individual films and associated data. Nowadays,
RIS PACS systems managed by radiology departments cover the entire clinical workflow of the medical
enterprise.
• Billing-Billing is made convenient through the system's financial record keeping and processing of
electronic payments and automated claims
Key Points to Remember
✓ Cardiology information system (CIS) is mainly focused on the storage and retrieval of cardiology-centric
images.
✓ The benefits and features of CIS include ease of access while maintaining data security, flexibility in
the workflow, and enhanced comparability.
✓ The functionalities of CIS are editing, viewing, and storing multi-modal cardiology data; remote access;
visualization and reporting capabilities, and EHR integration.
✓ A radiology information system (RIS) is a network software system designed to manage medical
imagery and associated data. A RIS is especially useful for tracking radiology imaging orders and billing
information, and is often used in conjunction with picture archiving and communication systems (PACS)
and vendor neutral archivals (VNA) to manage image archives and for record-keeping and billing within
a hospital information system (HIS).
✓ The functions of a RIS are patient management, scheduling, patient tracking, results reporting, image
tracking, and billing.
Materials Management System
The management function of hospital materials‒ that is, to ensure that services are rendered
successfully from one source to an end user-covers several areas of the hospital and could drastically affect
the expenses of the medical institution. Executing this function in a manner that lessens expenses and ensures
adequate cash flow requires effective management of a large amount of information from several sources.
To successfully manage such information, many hospitals implement a form of materials management
information system (MMIS). The aforementioned system can be used to manage functions like purchasing,
accounting, inventory management, and patient supply charges ("Materials management information
systems," 1996).
Purchasing
In HIS by BizBox, a purchase request marks the beginning of the procurement process. Using this
form, the user notifies the purchasing department regarding the needed items and services. It contains the
quantity, as well as a timeframe for the items requested. It has the authorization information needed to proceed
with the purchase. The requested items are then confirmed using the purchase order and a supplier is
nominated. Once completed, the order is sent to the supplier for processing.
Finally, the items are checked during receipt of the delivery. The receiver, which is usually the Central
Supplies department, uses the purchase order as basis for accepting the delivered items that should be
checked for indents and damages. Afterwards, the said items are then released to the requesting department.
Inventory Control
Inventory is one of the biggest expenses for most medical institutions (Johnston, 2014). Inventory
control plays an important part in refining the quality of health care services since lives of people are on the
line and medical costs are increasing.
Strategies in improving inventory control in the health care facility:
1. Ensuring Shipment Accuracy
Checking shipments for accuracy means ensuring that the received items are the ones ordered and
the supplies are free from possible damages during transit.
Enquiries and Quotations for Drugs, Consumables, Assets, and General Items
According to Webrino (2018), the following documents are required in the materials management
process:
1. Enquiries - The enquiries mark the beginning of the purchasing process. These establish the
relationship between the entity and the right supplier The supplier provides information on the
availability and price of the required items.
2. Quotations - Quotations contain vital information regarding the requirements which include price,
delivery details, payment terms, etc. Companies usually review two to three quotations before selecting
the supplier
3. Orders - The buyer shows the intention to purchase the required item by issuing a purchase order A
purchase order is placed to signify intention to engage in commercial operations for a specific product
or service. Upon agreement, the order becomes a contract between the health care institution and the
supplier.
4. Invoices - An invoice is also called a bill. It is a commercial document that indicates the product
the ordered quantity, and the agreed price. The supplier issues this to the buyer to show the products
and services that were sold or provided to the buyer
5. Documents - Documents are statutory requirements used during purchase and sales transactions
These ensure smooth transition and completion of the process.
Preferred Vendors
Companies typically maintain a list of preferred vendors from whom inventory items are usually
purchased. They look for a vendor who has on-time performance, offers reasonable costs, provides high-
quality products and services, offers fully licensed, bonded, and insured products and services, and has good
business practices.
Purchase Orders
A purchase order is a legally binding contract which shows that the seller has already accepted the order
issued by the buyer (SAP, 2012). It should contain: information about the buyer and seller (name, address,
contact details, etc.) order number and order date; item description (quantity, unit, and total price); shipping
information (shipping date and address); billing address; and the authorized signature.
Approval Process
The person who creates the document, either a purchase request or order, is the originator. When the said
originator adds document/s to the materials management system, the system checks for any approval
requirements. If the document fails to meet the approval requisites, the originator is notified that the document
needs approval. The document is temporarily saved as a draft.
When the approval process is launched, an internal request is immediately sent to the first approval
stage. This request is received in the Messages/Alerts Overview window, and the approver can access the
document. Approval can be done through a mobile phone if the devices are integrated. An internal
notification goes back to the originator with a link to the rejected document when the approver rejects the
document. The originator can amend the document, and the approval procedure will continue until the
conditions are adequately satisfied (SAP, 2012).
Quarantine Stock/Inventory
When undecided about how to handle defective goods, whether to be sold as scrap, reworked,
returned, or used as it is, a quarantine location or warehouse can be used to temporarily house them until a
final decision is reached.
Inventory is put into quarantine if it is initially rejected during (Infor LN Warehousing, 2018):
• Production, upon completion of an operation, when specified as "Move Rejected End Item to
Quarantine”.
• Inbound inspection upon receipt of:
✓ Manufactured end items
✓ Purchased items
✓ Sold items on sales return orders
✓ Enterprise planning distribution orders
✓ Outbound inspection upon issue of materials to production.
Issue Methods
Inventory management is a crucial function for any product-oriented business Common inventory handling
methods include
a. First In, First Out (FIFO)- Inventory items are sold based on the order they are purchased. This is the
most common technique.
b. Last In, First Out (LIFO) - Last items to enter the system are sold first. This is common among non-
perishable items like petroleum, minerals, and metals.
c. First Expired, First Out (FEFO) - Materials are sold based on the dates they should be consumed,
regardless of when they were purchased.
Generic Tax Formula Configurations
Materials management systems usually allow tax rates to be defined internally via tax codes, or
imported from an external source. Tax configurations are usually accounted on a per country basis. The
following taxes that can usually be processed while posting documents are
• Inventory services provide labor and automation to quickly count inventory and minimize shutdown
time.
• Inventory control system software can speed up the physical inventory process. . A perpetual inventory
system tracks the receipt and use of inventory, and calculates the quantity on hand.
• Cycle counting, an alternative to physical inventory, may be less disruptive.
The materials management systems offer all of these in addition to the barcode and RFID capability which
are supplementary technologies placed to give the institution more accurate and less burdensome inventory
counts.
Key to Remember
✓ To successfully manage information, many hospitals implement a form of materials management
information system (MMIS). The aforementioned system can be used to manage functions like
purchasing, accounting, inventory management, and patient supply charges
✓ Purchasing request could be used as a first step in the process of purchasing. This could be followed
by a quotation before proceeding to the purchase order depending on the process preferred by the
management.
✓ Inventory control plays an important role in refining the quality of health care services and different
strategies can be employed to ensure efficiency. These strategies include ensuring shipment accuracy,
aligning with sales projections, complying with regulations, and establishing buying cycles.
✓ The MMS can handle issues such as item indents and reorder level.
✓ There are three issue methods that are currently used in the health care industry: First In, First Ou t
(FIFO); Last In, First Out (LIFO); and First Expired, First Out (FEFO).
✓ Periodic physical stock taking or inventory count may be mandated by financial accounting. MMS have
barcode and RFID that can be used as tools to ensure accurate and convenient counting.