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Kuliah Kegawatdaruratan Di Bagian Penyakit Dalam PDF Free
Kuliah Kegawatdaruratan Di Bagian Penyakit Dalam PDF Free
Kuliah Kegawatdaruratan Di Bagian Penyakit Dalam PDF Free
KEGAWATDARURATAN DI
BIDANG ILMU PENYAKIT DALAM
Pendahuluan
• Pendekatan gawat darurat berdasarkan tanda
dan gejala
• “Basic Life Support”
• 43 topik kajian dalam modul IMELS, tema
disajikan berdasarkan kekerapan ditemui dalam
keseharian pasien2 penyakit dalam
• Menjaga serta meningkatkan kompetensi dokter
SpPD
• Mampu memberikan pelayanan kegawatdarutan
yg optimal demi peningkatan pelayanan bagi
masyarakat.
Kegawatdaruratan Di Bidang
Ilmu Penyakit Dalam
• Syok hipovolemik
• Syok anafilaktik
• Henti jantung
• Intoksikasi dengan ancaman hidup
• Sindrom distres pernafasan akut
• Pneumonia berat
• Pneumotoraks
• Efusi pleura masif
• Jejas paru karena suhu (trauma inhalasi)
• Emboli paru
• Gagal hati akut
Kegawatdaruratan Di Bidang
Ilmu Penyakit Dalam
• Ensefalopati hepatikum
• Kolangitis akut
• Pankreatitis
• Kolesistitis akut
• Hematemesis melena
• Hematoskezia
• Ileus paralitik
• Krisis hipertensi
• Hipokalemia
• Hiperkalemia
• Hiponatremia
Kegawatdaruratan Di Bidang
Ilmu Penyakit Dalam
• Hematuria masif
• Gangguan ginjal akut
• Bradikardia simtomatik
• Takikardia dengan pulse
• Sindroma koroner akut
• Edema paru akut kardiogenik
• Sindrom delirium akut
• Koagulasi intravaskular diseminata
• Sindrom vena kava superior
• Sindrom lisis tumor
• Ketoasidosis diabetikum
Kegawatdaruratan Di Bidang
Ilmu Penyakit Dalam
• Hipoglikemia
• Krisis tiroid
• Sepsis
• Leptospirosis (sindrom Weil)
• Malaria berat
• Tifoid toksik
• Keracunan makanan
• Tertelan zat korosif
• Gigitan binatang berbisa
• Sengatan panas
Shock
• Definition
• Epidemiology
• Physiology and Pathophysiology
• Classes of Shock
• Clinical Presentation
• Management
• Controversies
Definition
• A physiologic state characterized
by
– Inadequate tissue perfusion
• Clinically manifested by
– Hemodynamic disturbances
– Organ dysfunction
Epidemiology
• Mortality
– Septic shock – 35-40% (1 month
mortality)
– Cardiogenic shock – 60-90%
– Hypovolemic shock –
variable/mechanism
Physiology
• Basic unit of life = cell
• Cells get energy needed to stay alive
by reacting oxygen with fuel (usually
glucose)
• No oxygen, no energy
• No energy, no life
Physiology
• Cardiovascular System
– Transports oxygen, fuel to cells
– Removes carbon dioxide, waste products
for elimination from body
Hypoperfusio
n = Shock
Physiology
• What is needed to maintain
perfusion?
– Pump : Heart
– Pipes : Blood vessels
– Fluid : Blood
• How can perfusion fail?
– Pump Failure
– Pipe Failure
– Loss of Volume
Pathophysiology
• Imbalance in oxygen supply and demand
• Conversion from aerobic to anaerobic
metabolism
• Appropriate and inappropriate metabolic
and physiologic responses
• Characterized by three stages
– Preshock (warm shock, compensated shock)
– Shock
– End organ dysfunction
Pathophysiology
• Compensated shock
– Low preload shock – tachycardia, vasoconstriction,
mildly decreased BP
– Low afterload (distributive) shock – peripheral
vasodilation, hyperdynamic state
• Shock
– Initial signs of end organ dysfunction
– Tachycardia
– Tachypnea
– Metabolic acidosis
– Oliguria
– Cool and clammy skin
Pathophysiology
• End Organ Dysfunction
– Progressive irreversible dysfunction
– Oliguria or anuria
– Progressive acidosis and decreased CO
– Agitation, obtundation, and coma
– Patient death
Classification
• Schemes are designed to simplify
complex physiology
• Major classes of shock
– Hypovolemic
– Cardiogenic
– Distributive
Hypovolemic Shock
• Results from decreased preload
• Etiologic classes
– Hemorrhage - e.g. trauma, GI bleed,
ruptured aneurysm
– Fluid loss - e.g. diarrhea, vomiting,
burns, third spacing, iatrogenic
Hypovolemic Shock
• Hemorrhagic
Shock
Parameter I II III IV
Blood loss (ml) <750 750–1500 1500–2000 >2000
Blood loss (%) <15% 15–30% 30–40% >40%
Pulse rate
(beats/min) <100 >100 >120 >140
Blood pressure Normal Decreased Decreased Decreased
Respiratory rate
(bpm) 14–20 20–30 30–40 >35
Urine output
(ml/hour) >30 20–30 5–15 Negligible
CNS symptoms Normal Anxious Confused Lethargic
381.
Cardiogenic Shock
• Results from pump failure
– Decreased systolic function
– Resultant decreased cardiac output
• Etiologic categories
– Myopathic
– Arrhythmic
– Mechanical
– Extracardiac (obstructive)
Distributive Shock
• Results from a severe decrease in
SVR
– Vasodilation reduces afterload
– May be associated with increased CO
• Etiologic categories
– Sepsis
– Neurogenic / spinal
– Other (next page)
Distributive Shock
• Other causes
– Systemic inflammation – pancreatitis,
burns
– Toxic shock syndrome
– Anaphylaxis and anaphylactoid
reactions
– Toxin reactions – drugs, transfusions
– Addisonian crisis
– Myxedema coma
Distributive Shock
• Septic Shock
Clinical Presentation
• Clinical presentation varies with type
and cause, but there are features in
common
• Hypotension (SBP<90 or Delta>40)
• Cool, clammy skin (exceptions – early
distributive, terminal shock)
• Oliguria
• Change in mental status
• Metabolic acidosis
Evaluation
• Done in parallel with treatment!
• H&P – helpful to distinguish type of shock
• Full laboratory evaluation (including H&H,
cardiac enzymes, ABG)
• Basic studies – CxR, EKG, UA
• Basic monitoring – VS, UOP, CVP, A-line
• Imaging if appropriate – FAST, CT
• Echo vs. PA catheterization
– CO, PAS/PAD/PAW, SVR, SvO2
Treatment
• Manage the emergency
• Determine the underlying cause
• Definitive management or support
Manage the Emergency
• Your patient is in extremis –
tachycardic, hypotensive, obtunded
• How long do you have to manage
this?
• Suggests that many things must be
done at once
• Draw in ancillary staff for support!
• What must be done?
Manage the Emergency
• One person runs the code!
• Control airway and breathing
• Maximize oxygen delivery
• Place lines, tubes, and monitors
• Get and run IVF on a pressure bag
• Get and run blood (if appropriate)
• Get and hang pressors
• Call your senior/fellow/attending
Determine the Cause
• Often obvious based on history
• Trauma most often hypovolemic
(hemorrhagic)
• Postoperative most often hypovolemic
(hemorrhagic or third spacing)
• Debilitated hospitalized pts most often septic
• Must evaluate all pts for risk factors for MI
and consider cardiogenic
• Consider distributive (spinal) shock in trauma
Case
• 85 y/o M 4 hours postop S/P sigmoid
resection for perforated diverticulitis
is hypotensive on a monitored bed at
70/40