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International Journal on Engineering Applications (I.R.E.A.), Vol. 7, N.

4
ISSN 2281-2881 July 2019

Modeling and Identification of Human Heart System

Lafta E. J. Alkurawy, Mohammed S. Saleh, Ibraheem S. Fatah, Adham H. Saleh

Abstract – In this paper, for human heart problems, a mathematical model has been developed.
There are more or fewer applications of physical analog with mathematical modeling of the heart,
the modeling of heart by electromechanical, state-space. In this paper, the Physical models of the
heart can affect the data of real physiological focused on the actual tests present. A new technique
for mathematical modeling of heart of human is described as a hydro electromechanical system.
The human heart is described focusing on three systems: electrical analysis, hydraulic mechanism,
and mechanical variables. In the hydro model based on mechanical developed by using Laplace
transforms after converting the mechanical system to an electrical system and simulation are
carried out by using Matlab and the results are agreeable with the waveform of the ECG. The
components of electrical analysis have been exploited in order to put on the purposes of
physiological the human heart. The parameters of the electrical circuit have been transferred from
the model of hydraulic mechanism and medical physiological parameters. The results of the model
are close to true parameters. The identification of this model is applied with recursive least
squares (RLS) in order to compare the mathematical model. Copyright © 2019 Praise Worthy
Prize S.r.l. - All rights reserved.

Keywords: Modeling of Cardiovascular, Biomedical Systems, Identification, Recursive Least


Square, Control

I. Introduction are incorporated to physical model among different


independents. The Gaussian process was designed using
The main cause of human death is heart disease. The the sum functions of separable kernel, and was predicted
diseases are different, from the simplest one to the most by the function of marginal likelihood. They detected
difficult one and there are risk forms as the OSA by using the peripheral oxygen saturation signals
transplantation of a heart. The technological upgrade is and heart rate and conducted experiments on both real
feasible to get new chances in medical tools in order to and synthetic data in order to display the effectiveness of
inform heart risks. There are many modellings of human the OSA detection contrasted the approaches of data-
heart applied by a physical model and compare with real driven. Dongdong D., Peifeng J., Xuesong Y., and Ling
systems [1]-[23]. Martin J. Conlon, Donald L. Russell, X. [3] reconstructed a model based on the calculated
and Tofy M. [1] in 2005, proposed a parameter of tomography images. The atria included of crista terminal,
mathematical lumped model of heart of human, and they pectinase muscle, senatorial node and atrial muscles in
developed it in order to do vitro testing of ventricular this model. They made the calculation by using
devices. The model presented the heart and the interpolation technique in the linear manner and the
circulatory system (HCS) with components focused on position algorithm. The model of human heart
data of physiological. They presented two models for the experimentally measured in fibers orientation and put the
inspection of the dynamics of the circulatory system. whole heart inflammation propagation on using a model
Both models produced flow behaviors and pressure of mono domain. S. Malatos, A. Raptis and M. Xenos,
with physiologically sound. The result has – improved [4] proposed a model of flow the blood in the
the behavior of arterial due to the structural modification cardiovascular system. In this model, they used zero
easiness and has been explored when using the modeling dimensional and one- dimensional to study the human
by a computer data rather than modeling in physical data heart. The models for low dimensional include a time
such as an imitation circulatory. The lumped parameter dependent system that does not require spatial
advantages have been the ability to remove or add derivatives. There is a tendency of introducing 1D
segment, or the simple for simulation permit for very models; despite being more difficult, 3D cardiovascular
absorbing developed for the behavior the scale of micro models are suitable. The models of low dimensional can
circulatory. Gutta, S., Chang, Q., Nguyen, H. D., and give useful data to hospitals for the properties of blood
Benjamin, B. A. [2] proposed a new structure for OSA flow. Feneley et al. [5] transmitted the pressure of LV
identification in which the measurements that selected across the septum of ventricular into the RV. The data of
signals of the wearable sensor with the mathematical the model suggested that the outputs of function of
models of the cardiorespiratory system based on Vector

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130
L. E. J. Alkurawy et al.

enhanced RV systolic that increases MPA FCWee. Such doctor. The system monitors were irrespective of the
interactions add a large disrepair layer to the study of time and got the live updates concerning the heart rate of
waves of vascular and considering them may be patients and showed on the screen. Vasyl Kurylo and
important in the study of disease of Cardiovascular at Vasyl Varyshchuk [15] proposed a system for monitoring
‘local’ pathology may have ‘remote’ hemodynamics for non-contact and long term for a heart rate of human
consequences. F. N. Vanda Voss [6] made a constructed on the analysis of a video images processing
mathematical modeling of arterial fluid dynamics and algorithm from the web camera. They have examined the
this was important for physiological understanding measurement accuracy and the quality of the signal with
diagnostic and medical planning. A cardiac machine, conditions. The algorithms depended on the distance of
pressure and flow wave pressure for modeling and the user from the camera has a noteworthy result on the
references was given to the contributions of the issue. condition of the detected signal. Researching the actions
The mathematical modeling contributes to both of the location and size of the discovered area has
fundamental and applied cardiovascular. Y. Wu, P. E. displayed that the method can be exploited for different
Allayer, G. Tao, D. Olsen [7] proposed to integrate the places of the human body and it has been found out that
nervous model systems with the mathematical model of the movements of the users during the testing have a
Windkessel, in order to explore the control of the noteworthy effect on the precision of the measurement of
mechanism of the heart differently. In order to put back heart rate. Mehrdad Nosrati and Negar Tavassolian [16]
the human heart functions in a restricted time, they have presented an experimental study and a theoretical signal
used the pumps of the heart. The heart pumps mostly put modeling for heartbeat and algorithm for estimating by
back of ventricular left was a failure. Three pump using a radar of 2.4-GHz Doppler. They designed the
generations are available: pumps of rotary with technique the signal of the heartbeat and provided heart
noncontact bearing, pulsatile pumps, and the pumps of rate guides from the human body with a distance 1.5 m.
rotary are with contact bearing. The advanced pump such They made a model with Gaussian pulse train for the
as a heart serve tool is a flow heart pump with signal of heart rate and incorporated auto correlation and
magnetically levitated axial. [7]. Andriy Temko [11] technique of frequency-time phase for high accuracy of
estimated the heart rate (HR) from the signal of the human heartbeat rate and the design was robust,
photoplethysmographic through exercises of intensive accurate, and simple an average heart beat accuracy of
physical. He estimated HR by using Viterbi decoding the over 90% at the distance of 1.5 m from the subject. Soo
designed without monitoring HR and the estimated Young Sim, Han Byul Kim, Seungiin Jang, Beomoh Kim
performance of the HR system was compared with and Kwan Suk Park [17] inquired the feasibility of
algorithms on the database of public for 23 recordings. monitoring heart rate in the prediction of rhythm and
The algorithm has a minimum cost of computation body temperature. The core body temperature and the
and is satisfactory in monitoring of health and tracking of diverse parameters of heart rate were simultaneous got in
fitness in wearable devices. Sinan S. Mohammedsheet 21 healthy, subjects of ambulatory during the routine life.
and Mothanna Sh. Aziz [12] designed a mobile heart rate The analysis of regression was better in temperature of
and low cost system construct on the micro-controller for daily body and meson prediction, the extending of
heart health monitoring. They used IR filter sensor for Kelman filter got a good accuracy in atrophies and
heart pulse depending on the signal of biomedical a amplitude prediction. Alan H. Gee, Riccardo Barbieri,
conditioning circuit structured the signal processing. The David Paydarfar and Premananda Indic [18] investigated
results are expected to be monitored by a team of the fluctuation of heart rate for an infant with application
physician and heart rate will be easy for reading and gave the theory of point process and took this test for 10
an accurate heart rate counting and good response with infants, and they predicted the measures of instantaneous
low error. Atsushi Mase, Yuichiro Kogi and Toru linear for the signals of heart rate neonates. These
Maruyama [13] presented vital signals measurement by measures are used to take out statistical properties of
using microwave reflectometry. They focused on the bradycardia. They obtained good results with the
measurement of real time of heart rate variability (HRV) estimation algorithm by using measures of instantaneous
and heart rate (HR), carried them out by conventional linear for events with 440 bradycardia. This algorithm
electrocardiograph, and reflected meter for each other provided a forecast time of 116 seconds and their
comparison. This technique can evaluate the stress by analysis divulged that the heart rate signal increased and
reflects meters of microwave in various environments this leader with the increase in power from low levels.
such in life conditions. Abhiyah Hodge, Hrishikesh Alberto Hernando, Jesùs Làzaro, Eduardo Gil,
Humnabadkar and Akshay Bidwai [14] provided cure Adriana Arza, Jorge Mario Garzòn [19] studied and
and help to heart patients and produced a revolution in developed the heart rate and respiratory rate of young
the health sector. They brought a system that is less healthy volunteers by changing the test of Trier social
expensive and organized in monitoring in heart rate. The with computing the parameters of frequency domain by
system sent a signal the micro-controller if a heart rate time-frequency analysis in the traditional bands. The
got from heartbeat sensor was greater than the set limit respiratory rate has been predicted, and this information
and the controller sent a message through wireless has been incorporated in heart rate analysis by two
through a module and controlled gain to give alarm to methods: the high frequency band to point at frequency

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131
L. E. J. Alkurawy et al.

or respiratory and the analysis those infants where the ( )= ( )+ ( ) (2)


frequency falls with the low frequency band. They got a
good result considering respiratory rate information with ( )= 1( ) + 1( ) + ( ) (3)
power in high discriminative and it is as the potential of
the index between stress and relax stages. Yang Zheng, 1( ) = ( )+ 1( ) + ( ) (4)
Xianxiang Chen, Zhen Fang and Shanhong Xia [20]
developed the analysis of HRV system based on web and ( )= 2( ) + 1( ) + ( ) (5)
cloud platform application. The results of heart rate
analysis showed on the web attain good interactivity 2( ) = ( )+ 1( ) ( ) (6)
using Eckhart. The preliminary results showed that the
system has good calculating and good user experience. ( )= ( )+ ( ) (7)
The paper will show how to do the mathematical
model depending on measurements of data on clinic and ( )= ( )+ 1( ) (8)
after that, modeling will be done by Recursive least
square and compared between the two data output; by 1( ) + 4( ) + 6( ) + 2( ) = ( ) (9)
this algorithm any kind of control can be done on
recursive least square before applying it on human heart.
In Section II, the modeling for compartment hydro
electromechanical (HEMS) with all the questions needed
to build that model and simulation of a first pulse of a
first human heart and second pulse of second heart is
studied. Section III describes the recursive least square
model for both first pulse for first and second human and
the differences between two models by comparing the
results and Section IV will show the conclusion for this
paper.

II. Modeling of the System


S. Wenyu and M. S. Chew proposed a physical analog Fig. 1. Compartmental hydro electromechanical model (HEMS)
model and mathematical model of an artificial heart in
order to predict the human heart system [8], [9]. G. Tao, Differentiating both sides of the first group of
and D. Olsen also introduced a model with state space compartmental equations, it is:
equation done by the output of an analysis of the total of
artificial heart for human circulatory [3]. It has one ( ) 1
parameter with critical time varying. An identification ( )+ + + ( ) (10)
model with recursive least square to model the human
heart has been estimated to track a command signal ( ) 1
calculated by a nonlinear function of total artificial heart ( )+ + ( ) (11)
pump head to agree with the total heart physiological
need. ( ) 1
They used the simulated program in Matlab in order to ( ) ( )+ + ( ) (12)
check the systems of human heart to be with ventricular
in the left aid instrument and there will be a physiological
( )+ = ( ) (13)
controller. Different physiological conditions have been
assessed to test human heart and designed a controller of
the physiological system has been designed. The output ( ) ( ) 1
+ + ( )
of experimental and simulation shows that the pressure (14)
prediction error of heart aortic is small, and the heart ( )
unusual variables of hemodynamic of patient heart +
reinstated back to total heart normal physiological
average. The model expanded is shown in Fig. 1. The ( ) ( ) 1
+ + (15)
mathematical model analysis focused on symmetry
characteristic of heart of human with circulatory system
with two parallel circuits. The electric model of ( ) 1
( ) + + ( ) (16)
compartment with parameters of the system (hydraulic
and electrical parameters) is shown in Figures 2-5:
( ) ( ) ( )
( )= ( )+ 1 (1) + = (17)

Copyright © 2019 Praise Worthy Prize S.r.l. - All rights reserved International Journal on Engineering Applications, Vol. 7, N. 4

132
L. E. J. Alkurawy et al.

1.4
By taking Laplace transform for both sides of the
1.2
equations:
1

0.8 ( )[ + ( + )]
1 (18)
Amplitude

0.6
++ ( ) − +
0.4

0.2
( )[ + ( )] (19)
0

-0.2
( )[ + ( + )] (20)
-0.4
0 1 2 3 4 5 6 7 8 9 10
Time/ seconds
1 1
( )+ ( )+ ( )[ + ]
Fig. 2. The output of the first pulse (21)
for the first human heart from clinical studies =[ ( )]
0.8

0.6
Differentiating both sides equations of the second
group of compartmental:
0.4

0.2
1( ) + 3( ) + 5( ) + 6( ) = ( ) (22)
Amplitude

-0.2 ( ) 1
( )+ + + ( ) (23)
-0.4

-0.6
( ) 1
-0.8 ( )+ + ( ) (24)
-1
0 1 2 3 4 5 6 7 8 9 10
Time / seconds
( ) 1
Fig. 3. The output of the first pulse ( ) ( )+ + ( ) (25)
for a second human heart from clinical studies

( )+ = ( ) (26)

Differentiation of the equation above for both sides:

( ) ( ) 1
+ + ( )
(27)
( )
+

( ) ( ) 1
+ + (28)

( ) 1
Fig. 4. The output model of the first pulse for the first human heart ( ) + + ( ) (29)

( ) ( ) ( )
+ = (30)

By taking Laplace transform for derived equation to


both sides:

( )[ + ( + )]
1 (31)
+ ( ) − +

( )[ + ( )] (32)

Fig. 5. The output model of the first pulse of a second human heart ( )[ + ( + )] (33)

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133
L. E. J. Alkurawy et al.

1 1
( )+ ( )+ ( )[ + ] ∗ ∗(
(34) = = ) ( ) (39)
=[ ( )]

Various mathematical models and programming - Update of :


simulation by using software codes in MATLAB have ∗( ( + 1))
=( + + 1) (40)
been expanded as a hydroelectromechanical system and
it is based on physical and electrical model as shown in ∗(
+ 1) ( + 1)
Figures 4 and 5 and the data is in accordance with the = − ∗ ( + 1)
(41)
1+ ( + 1)
data got from clinical studies as shown in Figures 2 and 3
and the results of the mathematical model and data from - Recursive Least Square algorithm:
the clinic are very close each other and that means that
the mathematical model is identical for these data. ∗(
+ 1) ( + 1)
= − ∗ ( + 1)
(42)
1+ ( + 1)
∗(
III. Recursive Least Square Modeling = + + 1) ( + 1) (43)
( )
Recursive Least Squares Method has many = (44)
applications. Nowadays, a model that can work with
online data while the system is in operation is needed Initialization = 0 and = , where is a
[10]. The model includes the preceding information and very small positive constant. The recursive least Square
new information; it alters its model boundary values to is an algorithm used to estimate the true system to get a
lower the error between the estimated data and real one. transfer function with numerator and denominator as the
There is a need for these systems, if the result obtained same response of true system but it is not in the same
is necessary in real time or it is essential to take some order, and it has been noticed that the mathematical
conclusion about time with new discovered data. model developed in section (II) is the same response of
Methods that try to solve these problems or try to RLS in Fig. 7 and Fig. 8 and that means the RLS is a
adapt the system with an arrival of successive data good algorithm to identify and predict the true system,
usually are called adaptive systems. and the transfer function of RLS can be used to control or
any function.
System 1.4
MRN output ---
Plant output
1.2

0.8
Model
0.6
output

Fig. 6. Adaptive methods 0.4

0.2
The method used to calculate a mathematical
modeling with online data is called recursive 0

identification methods, because data are processed -0.2

recursively as they are obtained. Other names for this -0.4


0 1000 2000 3000 4000 5000 6000 7000 8000 9000 10000
algorithm are real time identification or on-line Number of samples

identification.
Fig. 7. RLS output of a first pulse for the first human heart
RLS Algorithm:
- Supposing a time , it is known that: 1
MRN output ---
Plant output
0.8
= [ (0), … … … … , ( )] (35)
0.6
= [ (0), … … … , ( )] (36)
0.4
output

The solution to min ‖ − ‖ is:


0.2

( ) ∗ ∗
=( ) = (37) 0

where: -0.2

-0.4
0 100 200 300 400 500 600 700 800 900
∗ ∗( ) ()
= = (38) Number of samples

Fig. 8. RLS output of a first pulse for a second human heart

Copyright © 2019 Praise Worthy Prize S.r.l. - All rights reserved International Journal on Engineering Applications, Vol. 7, N. 4

134
L. E. J. Alkurawy et al.

IV. Conclusion human heart, Pathophysiology and Natural History, Vol 71, Issue
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to the generation of right ventricular systolic pressure in the Jorge Mario Garzon, Inclusion of respiratory frequency

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L. E. J. Alkurawy et al.

information in heart rate variability analysis for stress assessment, Ibraheem S. Fatah receives a bachelor’s degree
IEEE of Biomedical and Health Information, Pages 1016-1025, in electronic engineering from government of
Vol 20, Issue 4, 2016. Yugoslavia and receives a master degree in
doi: 10.1109/JBHI.2016.2553578 electronic engineering from government of
[20] Yang Zheng1, Xianxiang Chen, Zhen Fang and Shanhong Xia, A Yugoslavia too. The area of research interest is
Heart Rate Variability Analysis System Based on LeanCloud and in electrical machines and control.
Echarts, IEEE 40th Annual Computer Software and Applications E-mail: Ibrahim.saadoon@yahoo.com
Conference, Vol 2, 2016.
doi: 10.1109/COMPSAC.2016.229
[21] Hendradi, R., Arifin, A., Shida, H., Gunawan, S., Purnomo, M., Assist. Prof Adham Hadi Saleh received a
Hasegawa, H., Kanai, H., Signal Processing and Extensive bachelor's degree in electronic engineering from
Characterization Method of Heart Sounds Based on Wavelet the University of Diyala in 2006 and received a
Analysis, (2016) International Review of Electrical Engineering master's degree in Electrical Engineering /
(IREE), 11 (1), pp. 55-68. Electronic from the University of Technology in
doi: https://doi.org/10.15866/iree.v11i1.8138 2012. Work in SAKAR company-electrical
[22] Aabid, M., Elakkary, A., Sefiani, N., Real-Time Cardiac generation station. The area of research interest
Monitoring Through the Application of an Adaptive Controller to is in the design of systems using VHDL
Human Heart, (2017) International Review of Automatic Control Artificial intelligence and image processing and digital signal
(IREACO), 10 (1), pp. 63-71. processing. He has more than scientific research published in local and
doi: https://doi.org/10.15866/ireaco.v10i1.11014 international journals.
[23] Aabid, M., Elakkary, A., Sefiani, N., PID Parameters E-mail: adham.hadi@yahoo.com
Optimization Using Ant-Colony Algorithm for Human Heart
Control, (2017) International Review on Modelling and
Simulations (IREMOS), 10 (2), pp. 94-102.
doi: https://doi.org/10.15866/iremos.v10i2.11230

Authors’ information
Department of Electronics Engineering, College of Engineering,
University of Diyala, Iraq.

Lafta E. Jumaa Alkurawy received the B.S.,


and M.S. degree in Control and systems from
Technology University, Baghdad, Iraq, in 1996
and 2003 respectively. He received the Ph.D.
degree in Electrical and Computer Engineering
from the University of Missouri in Columbia,
USA, in 2013. Since 2003, I have been with the
University of Diyala, College of engineering,
Diyala, Iraq as a lecturer. His current research interests include
modeling, control, Numerical analysis and nonlinear
E-mail: Lafta_67@yahoo.com

Mohammed Salman Saleh was born in Diyala,


Iraq. He received his B.Sc. Degree in Electrical
Engineering from the Military Engineering
Collage, Baghdad, Iraq, in 1989.In 1998, He
received Master Degree in Control and
Automation Engineering form Military
Engineering Collage, Baghdad, Iraq. in 2012, He
received PhD Degree in Control and Automation
Engineering from the University of Technology, Baghdad, Iraq. He is
Currently Lecturer at Electronic Engineering Department- College of
Engineering- University of Diyala - Iraq. His Current Research Interests
Include Neural Control System, Fuzzy Logic Control Systems,
Enhanced Fuzzy (Fuzzy Type II) control system and Robot Control
System.
E-mail: mohsalman@gmail.com

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