Operation Manual

Electrolyte Analyzer
About this Manual

Release Date: March 2015

Item No.: P01.91.300253-00

Statement

This manual will help you understand the operation and maintenance
of the product better. It is reminded that the product shall be used
strictly complying with this manual. User’s operation failing to comply
with this manual may result in malfunction or accident for which the
manufacturer cannot be held liable.

The manufacturer owns the copyrights of this manual. Without prior

written consent of the manufacturer, any materials contained in this
manual shall not be photocopied, reproduced or translated into other
languages.

Materials protected by the copyright law, including but not limited to

confidential information such as technical information and patent
information are contained in this manual, the user shall not disclose
such information to any irrelevant third party.

The user shall understand that nothing in this manual grants him,
expressly or implicitly, any right or license to use any of the intellectual
properties of the manufacturer.

The manufacturer reserves the right to modify and update this manual
without prior notice.

I
The manufacturer reserves the final explanation right to this manual.

Warning

This system can only be operated by test professionals, doctors, lab

workers or personnel for system maintenance and troubleshooting,
who have been trained by the manufacturer.

It is important for the hospital or organization that employs this

equipment to carry out a reasonable maintenance schedule. Neglect of
this may result in machine breakdown or injury of human health.

Make sure to use the instrument under the provisions of this Operation
Manual. Otherwise, the instrument may not work normally, the test
result is unreliable and it may damage the instrument parts and
endanger people’s safety.

Preface

This operation manual is applicable to the Electrolyte Analyzer.

The Electrolyte Analyzer takes only 100μL~200μL sample to test the

ion concentration in serum. Its analysis speed is very fast, takes only
60 seconds for one test.

The LCD touch screen and thermal printer are convenient for users to
operate. The advanced ion selectivity electrode (ISE) test method is
used to ensure the accuracy and reliability of the results. Storage of
more than 2000 results can meet the general need.

II
This operation manual includes instructions and precautions of
installation, operation, maintenance and service for the electrolyte
analyzer. Please read this manual carefully before operating the
instrument.

For the convenience of users, the manufacturer provides a series of

technical support. Firstly, provide free technical training about the
instrument’s operation and maintenance, etc. Secondly, provide
original and suitable reagents of the instrument. Thirdly, build up an
excellent service team to guarantee good and efficient maintenance
service.

This operation manual mainly intends to help users learn about the
safety, installation, structure, analysis principle, operating procedures,
maintenance and service, problems and troubleshooting, etc. of the
Electrolyte Analyzer. Please follow this manual to operate the
instrument.

III
 Table of Contents

Chapter 1 Instrument Introduction .............................................. 1

1.1 Test Principle ......................................................................... 1

1.2 Technical Indicators ............................................................... 1

1.3 Structure Introduction ............................................................ 3

1.3.1 Front view of the instrument .......................................... 3
1.3.2 Back view of the instrument ........................................... 4
1.3.3 Menu interface ............................................................... 4
1.3.4 Reagent introduction ...................................................... 5

1.4 Symbols, Screen Printings, Labels and Pictures .................. 5

1.4.1 Symbols ......................................................................... 5
1.4.2 Screen printings and labels ........................................... 7
1.4.3 Pictures .......................................................................... 8

1.5 Warranty and Service ............................................................ 9

1.5.1 Warranty......................................................................... 9
1.5.2 Contact information ........................................................ 9

1.6 Training ................................................................................ 10

Chapter 2 Safety and Precautions ............................................. 11

2.1 Safety................................................................................... 11

2.2 Precautions .......................................................................... 12

Chapter 3 Installation .................................................................. 15

IV
 3.1 Working conditions .............................................................. 15

3.2 Installation............................................................................ 16
3.2.1 Installer......................................................................... 16
3.2.2 Damage check ............................................................. 16
3.2.3 Packing list ................................................................... 17
3.2.4 Installation .................................................................... 17

Chapter 4 Interface Structure and Operation ........................... 19

4.1 Interface structure and function ........................................... 19

4.2 Start up procedures and precautions .................................. 30

4.3 Auto calibration .................................................................... 31

4.4 Measure ............................................................................... 33

4.4.1 Measuring flow chart .................................................... 33
4.4.2 Sample test .................................................................. 33
4.4.3 Sample test precautions .............................................. 36

4.5 Calibration ........................................................................... 37

4.6 Correction ............................................................................ 38

4.7 Quality Control (QC) ............................................................ 42

4.8 Setting.................................................................................. 45
4.8.1 Contrast ....................................................................... 46
4.8.2 Unit selection ............................................................... 47
4.8.3 Reference range .......................................................... 47
4.8.4 Date and time............................................................... 49
4.8.5 COM setting ................................................................. 49

V
 4.8.6 Printer setting ............................................................... 51
4.8.7 Test item setting ........................................................... 51
4.8.8 Exit ............................................................................... 52

4.9 Maintenance ........................................................................ 52

4.9.1 Sampling adjustment ................................................... 53
4.9.2 Instrument cleaning...................................................... 54
4.9.3 Potential track .............................................................. 56
4.9.4 Feed ............................................................................. 57
4.9.5 Exit ............................................................................... 57

Chapter 5 Maintenance and Service .......................................... 58

5.1 Tools Preparation ................................................................. 58

5.2 Daily maintenance ............................................................... 58

5.3 Weekly Maintenance ........................................................... 61

5.4 Unscheduled Maintenance .................................................. 61

Chapter 6 Problems and Troubleshooting ................................ 63

6.1 Circuit and detection system ............................................... 63

6.2 Liquid system ....................................................................... 64

6.3 Instrument alarm and handling ............................................ 66

6.4 Parts or consumables that can be replaced by customers . 68

6.5 Parts need to be replaced by service engineers ................. 68

Chapter 7 Common Consumables and Ordering Methods ..... 69

VI
Chapter 8 Transportation, Storage and the Outer Packing
Instructions .................................................................................... 71

8.1 Transportation and storage ................................................. 71

8.1.1 Transportation .............................................................. 71
8.1.2 Storage ......................................................................... 71

8.2 The outer packing instructions ............................................ 71

Chapter 9 Appendix ..................................................................... 74

9.1 Print paper replacing method .............................................. 74

9.2 Reagent replacing method .................................................. 75

9.3 Pump tube replacing method .............................................. 75

9.4 Electrode replacing method ................................................. 76

9.5 Instructions for ISE .............................................................. 78

9.5.1 Components of ISE ...................................................... 78
9.5.2 Electrode filling ............................................................. 79
9.5.3 Electrode service and maintenance............................. 79
9.5.4 Electrode storage ......................................................... 80

9.6 MSCOMM ............................................................................ 80

9.7 Barcode reader settings ...................................................... 84

VII
 Chapter 1 Instrument introduction

Chapter 1 Instrument Introduction

1.1 Test Principle

This electrolyte analyzer adopts the advanced ion selectivity electrode

(ISE) technology. The test principle is based on the Nernst response of
ISE, the relationship between the tested ion concentration and the
electrode potential could be described by the following Nernst formula:

ln(ai × fi)
2.303RT
E = E0 ±
nF
Among them:

E- Electric potential of ISE in ion solution, mV

E0- Standard electric potential of ISE, mV
R- Gas constant (8.314 J/(K•mol))
T- Thermodynamic temperature [273+t (℃)], K
n- Electric charge of sample ion
F- Faraday constant (96487 C/mol)
αi- Activity of ion, mol/L
fi- Activity coefficient of ion

It can be seen from the above formula that under certain condition,
there is a linear relationship between E and ln(ai×fi), so we can get “ai”
by testing E.

1.2 Technical Indicators

+ + - 2+
Application range: Applicable to the determination of K , Na , Cl , iCa ,
2+ +
TCa , Li concentration and pH in serum, urine and body fluid.

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 Chapter 1 Instrument introduction

Sample: Serum, urine, etc.

Sample volume: 100μL~200μL, adjustable

Test method: ISE technology

Test speed: ≥60 samples/hour

Memory: 2000 results

Display: 240*128 LCD screen

Inner printer: 24 bits thermal printer

Output: RS-232 port

Storage condition: Temp: 0~40℃ Relative Humidity: ≤85%

Working condition: Temp: 15~30℃ Relative Humidity: 20-80%

Power supply: ~100-240V 50/60Hz Power: ≤80VA

Electric shock level: Grade I Overvoltage category: Class II

Pollution degree: Grade II Management category: Class II

Weight: About 5Kg

Dimension: (L) 385mm*(W) 242mm*(H) 380mm

Divided by working system: continuous operation equipment

Device properties: IVD in vitro diagnostic device

2
 Chapter 1 Instrument introduction

1.3 Structure Introduction

This product consists of the analyzer and related reagents.

1.3.1 Front view of the instrument

Note: The object may not be exactly the same with the picture, please
refer to the real object provided.

3
 Chapter 1 Instrument introduction

1.3.2 Back view of the instrument

Note: The object may not be exactly the same with the picture, please
refer to the real object provided.

1.3.3 Menu interface

Fig. 1.1

4
 Chapter 1 Instrument introduction

After doing the Power On Self Test, the instrument enters into the main
interface, as shown in Fig. 1.1. There are six sub-menus, simply click
on the corresponding menu to make a selection.

1.3.4 Reagent introduction

This analyzer mainly uses electrode drift liquid (A liquid) (hereinafter

referred to as Standard A) and slope calibration liquid (B liquid)
(hereinafter referred to as Standard B). There are also other reagents
for electrodes cleaning and maintenance, as well as tubes cleaning,
including the reference electrode filling solution, ion electrodes (K, Na,
Cl, Ca, Li, PH) filling solution, cleaning solution, deprotein solution,
quality control (QC) solution and electrode activating solution.

All reagents are only used for in vitro diagnostic, usually stored at room
temperature (18~30℃), and shall be used within the period of validity.
Please use the reagent as soon as possible, and store the remaining
reagent in the refrigerator to maintain its effect, otherwise some
parameters will get changed after a long time placement. In order to
ensure the accuracy and reliability of the test results and trouble-free
operation of the instrument, please use the original reagents.

1.4 Symbols, Screen Printings, Labels and Pictures

1.4.1 Symbols

The symbols listed in the table below are applicable to this operation
manual.

5
 Chapter 1 Instrument introduction

Symbol Meaning

Note: May cause damage to the analyzer or affect

the test results.

Biohazard, do not touch directly.

May cause electric shock.

High temperature of the print head and its

surrounding area! May get burned after contact.
When replacing the print paper, stop printing first,
then wait at least 20 minutes to replace it.

Body injury, the sample probe and other moving

parts may lead to injury, please use with caution.

The operation interface described in this manual

may be different from the real object due to the
altered software version or model, please refer to

6
 Chapter 1 Instrument introduction

Symbol Meaning
the real operation interface.

Note: Corrosion

Cleaning solution is chemically corrosive, gloves

should be worn while in operation.

1.4.2 Screen printings and labels

The screen printings and labels listed in the table below are applicable
to this operation manual.

Label Meaning

Product serial number

Equipotential terminal, connected with the ground

cable

Production date

In vitro diagnostic devices, only for in vitro auxiliary

diagnosis

～ Alternating current

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 Chapter 1 Instrument introduction

Power on

Power off

Peristaltic pump rotates in the direction as indicated by

the arrow

A, B Standard A, Standard B

POWER Main power supply

COM Communication port 1, connected with the PC serial

RS-232 1 port

Reagent Place the reagents

Room

Waste Waste outlet

1.4.3 Pictures

Pictures in this manual are only for illustration or examples, not for
other purposes. Please refer to the real object while in operation,
modification may be made without prior notice.

8
 Chapter 1 Instrument introduction

1.5 Warranty and Service

1.5.1 Warranty

The manufacturer warrants that this product will be free from defects in
materials and workmanship that occur within the warranty period. This
warranty shall not apply to damages caused by the following situations:

1) Operation environment does not meet the specified requirements;

2) Not use the specified power supply or power supply is abnormal;

3) Man-made damage;

4) Personnel not authorized by the manufacturer making the repair;

5) Other irresistible natural factors, such as earthquakes, fires, war,

etc.

6) Damage caused by accidents.

7) Replacement or removal of serial number label and manufacture

label.

If a product covered by this warranty is determined to be defective

because of defective materials, components, or workmanship, and the
warranty claim is made within the warranty period, the manufacturer
will, at its discretion, repair or replace the defective part(s) free of
charge. The manufacturer will not provide a substitute product for use
when the defective product is being repaired.

1.5.2 Contact information

If you have any question about maintenance, technical specifications

9
 Chapter 1 Instrument introduction

or malfunctions of devices, contact the manufacturer or your local

distributor.

1.6 Training

In order to help users properly use the Electrolyte Analyzer and give
full play to its performance, the manufacturer holds periodical free
training for users throughout the world, please visit the manufacturer’s
website or contact the local offices to get the training schedule.

Only personnel trained by the manufacturer or its authorized

distributors can operate this instrument, otherwise it may damage the
protection provided by the instrument.

Please carefully read this manual and the related reagents instructions,
if not operating in accordance with the provisions of this instrument
manual, it may damage the provided protection or greatly affect the
test results.

10
 Chapter 2 Safety and precautions

Chapter 2 Safety and Precautions

The following are the warning symbols related to this analyzer, if ignore
these symbols, the users may run the risk of death or serious injury.
The following warning symbols are not sorted by their importance, all
the symbols have the equivalent importance.

2.1 Safety
Electric shock
1) When the power supply is turned on, unauthorized
service technicians are prohibited to open the
analyzer’s panel.
2) Avoid spilling any liquid onto the workbench, if liquids
penetrate into the analyzer, please turn off the power
immediately and contact the manufacturer promptly.
Danger
1) Remove the sample when hearing a "di" alarm
sound, and pay attention to the sharp parts of the
analyzer, which may cause body injury.
2) When the analyzer is working, do not touch the
moving parts, such as the sample probe, peristaltic
pump, fan, etc.
3) While making the “exit” operation, the sample probe
automatically descends to the suction tank, pay
attention to the sharp parts of the analyzer.

11
 Chapter 2 Safety and precautions

Biohazard
1) All the test samples, calibrators, quality controls, etc.
should be regarded as infectious, gloves should be
worn while in touch;
2) All the waste liquids should be regarded as
infectious, gloves should be worn while in touch. All the
items contacted with the test samples, such as pipette
tips, measuring cups should be regarded as infectious,
gloves should be worn while in touch;
3) All the wastes are potentially infectious and should
be regarded as medical wastes and disposed according
to the current regulatory requirements;
4) When the instrument reaches its lifetime, it should be
disposed according to the requirements of the local
environmental protection department, cannot be
disposed and discarded as common wastes.
2.2 Precautions
Application Range
+
1) Applicable to the determination of potassium (K ),
+ - 2+
sodium (Na ), chloride (Cl ), calcium (iCa ), total
+
calcium (TCa), lithium (Li ) concentration and pH value
(pH) in human serum, urine, and body fluids.
2) When making a clinical judgment based on the test
results, please consider the clinical examination results,
other test results or clinical symptoms as well.
Operator
This analyzer can only be used by personnel who have
been trained and authorized by the manufacturer or its

12
 Chapter 2 Safety and precautions

distributors. Otherwise, it may damage the provided

protection or greatly affect the test results.

Application Environment
Please follow the installation environment and use
conditions specified in this manual to install the
instrument correctly. Otherwise, the test results may be
unreliable and the analyzer may be damaged.
Electromagnetic Interference
1) The analyzer is susceptible to electromagnetic
interference during running, which may affect the test
results and lead to incorrect operation. During its
running, please do not use devices that generate
electromagnetic waves, such as electric drill, mobile
phone, intercoms, etc.
2) The analyzer can emit electromagnetic waves during
running. Please do not install and use
electromagnetic-sensitive equipment near the analyzer.
Imperfect Earth
1) The power supply must be correctly grounded;
otherwise, there is a risk of electric shock.
2) The grounding impedance must be lower than 0.1Ω.
Imperfect earth may cause unstable test results and
electricity leakage of the shell, and thus lead to the risk
of electric shock.
Device Connection
1) For a non-permanent connection, please do not place
the device at a location where it is hard to disconnect.
2) For all the external switches or breakers and external

13
 Chapter 2 Safety and precautions

over-current protection device, it is recommended to

place them near the analyzer.
3) Devices connected with the COM RS232 or USB port
of this analyzer should conform to the requirements of
National Standard GB 4793, GB4943 and IEC60950 of
China.

Combustion
Do not use inflammable hazardous substances near the
analyzer, such as alcohol or ether, etc.

14
 Chapter 3 Installation

Chapter 3 Installation

3.1 Working conditions

The electrolyte analyzer is a precise electronic instrument, in order to

use it normally and get an accurate result, the environment and place
must meet the following requirements:

Content Requirements
Flat workbench with tilt < 1/200 and sufficient
intensity, which can bear the weight of 50kg;
Dust-free, without corrosive and inflammable gases,
Place
without heat source and wind source, without
mechanical vibration;
Avoid direct sunlight and with good ventilation.
Enough space to place the analyzer, minimum area
Space
of 0.48m (length ≥80cm, width ≥60cm).
2

Environment
15℃~30℃
temperature
Relative
20%~80%
humidity
Atmospheric
86kPa~106kPa
pressure
Able to exchange air with outside, smooth air flow,
Ventilation
no direct wind blow to the analyzer.
~100-240V, 50/60Hz, power supply correctly
Power supply grounded and the grounding impedance is less than
0.1Ω.

15
 Chapter 3 Installation

Do not close to an electric-brush engine or electric

devices which are frequently switched on/off;
Electromagnetic Do not place the analyzer and other high-power and
wave strong interference devices at the same room, such
as centrifuge, refrigerator, incubator or use the
same socket.
3.2 Installation
3.2.1 Installer

This electrolyte analyzer can only be installed by the manufacturer or

its authorized distributors, and the users are required to provide the
corresponding environment and space. When you receive this analyzer,
please notify the manufacturer and the local distributor immediately.

3.2.2 Damage check

All the analyzer packages have been strictly examined by the

manufacturer before shipment. When you receive the instrument,
please carefully check to verify whether there are the following
damages before opening the packaging box:

1) Inversion or deformity of the outer package;

2) Obvious moistened marks on the outer package;

3) Obvious crash marks on the outer package;

4) Indication of the outer package been opened.

Once you find any of the above issues, please do not open the
package and do not power on the instrument. Otherwise, it may lead to
electric shock. Please notify the local distributor immediately.

16
 Chapter 3 Installation

If the outer package is intact, please open the packaging box and
check the items in the box at the presence of the distributor or the
manufacturer:

1) Verify if all the components are equipped according to the packing

list;

2) Carefully check the appearance of all the components to verify

whether there is breakage, crash or deformity.

3.2.3 Packing list

Please check the Packing List in the instrument packaging box.

3.2.4 Installation

Open the dedicated packaging box of this analyzer and carefully verify
if the instrument and accessories in the box are consistent with the
packing list. If there is any loss or damage, please contact the supplier
at once;

If all the items are there, carefully take out the instrument and put it on
a stable workbench with good ventilation, do not place it near the wall
or other places where are difficult for disconnection;

Take out the power cable, plug one end into the supply hub at the rear
panel and insert the other end into the grounded three-wire socket. For
a non permanent connection, please do not place the device at a
location where is hard to disconnect;

Use the dedicated medical-use ground cable (grounding resistance

should be less than 0.1Ω) to connect the ground pole at the rear panel

17
 Chapter 3 Installation

with the steel pipe which is buried under the ground more than one
meter.

Take out the waste bottle from the packing box and put it at the right
side of the instrument, then put the waste tube into the bottle.

Take out the reagent bottle from the packing box, open the reagent
room, then put the reagent tube into the corresponding reagent bottle
and make sure the tubes reach the bottom of the bottle; please refer to
App. 2.

Install the electrodes, please refer to step 5) ~ 7) in App. 4.

Switch on the power button at the rear panel, after the system self-test
and auto calibration, the instrument is ready to be used.

Fuse model: F3AL250V.

Install the barcode reader, please refer to App. 7.

If connect to the computer, please refer to App. 6 for the settings.

18
 Chapter 4 Interface Structure and Operation

Chapter 4 Interface Structure and Operation

4.1 Interface structure and function

Interface menu structure and function are shown in the following table.

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

Sampli Aspirate
ng sample
Num Input the
Input
eric 13-digit ID
ID Click the
key NO.
Samp correspo
Directly
le nding
Input input the
type button on
NO. sample ID
(Seru the
Meas NO.
m, screen to
ure + Query the
CSF, realize
previous or
Urine, - the
Result next NO.
Other correspo
Print
s) Print nding
result
results function
s
Return to
Exit the
measurem

19
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

ent
interface
External
Bar
bar code
code
reader to
input
input
ID
13-digit ID
Return to
Exit the main
menu
Calibr Auto
ate calibration
Set the
Num Click the
correspond
Samp eric correspo
ing target
le Select key nding
value
type items button on
Save the
(Seru (K, the
Corre changes
m, Na…) screen to
ct and return
CSF, to be Enter realize
to the
Urine, correct the
previous
Other ed correspo
interface
s) nding
Return to
Exit function
the

20
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

previous
interface
without
saving the
changes
Delete the
Del input
number
Aspirate
sample/sta
Sam
ndard
pling
solution/Q
Autom
C solution
atic
Return to
the
Exit
correction
interface
Modify
Num factors of
eric the
Manual key correspond
ing ions
Rese Restore
t the

21
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

modified
factor to
the initial
value
Return to
the
Exit
correction
interface
Return to
Exit the main
interface
Aspirate
Sampl
QC Click the
ing
Samp solution correspo
le + Query the nding
type Quality previous or button on
-
(Seru control next NO. the
Meas
QC m, (QC1, Delete the screen to
ure
CSF, QC2, result with realize
Result Del
Urine, QC3) the shown the
Other No. correspo
s) Print nding
Print
results function
Exit Return to

22
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

the
previous
menu
Return to
the
Exit
previous
menu
Set the
Nume correspond
ric ing lot
key number
code
Save the
changes
and return
Lot Enter
to the
No.
previous
interface
Return to
the
previous
Exit
interface
without
saving the

23
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

changes

Delete the
Del input
number
Calculate
SD value
Stat
and CV
value
Return to
the
Exit measurem
ent
interface
Increase or Click the
+
decrease correspo
the screen nding
Contr -
contrast button on
ast
Settin Return to the
gs Exit the setting screen to
interface realize
mmol/L After the
Units selected, correspo
mg/dL
the nding

24
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

instrument function
automatica
lly
performs
the unit
conversion
Return to
Exit the setting
interface
Nume Set the
ric correspond
key ing value
Save the
Sampl changes
Item
e type and return
(K, Enter
(Serum to the
REF Na…
, CSF, previous
STD )
Urine, interface
rang
Others) Return to
e key
the
previous
Exit
interface
without
saving the

25
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

changes

Delete the
Del input
number
Set the
Numeri
correspond
c key
ing value
Save the
changes
and return
Enter
to the
previous
interface
Set
Return to
Time
the
previous
Exit interface
without
saving the
changes
The cursor
Del moves
backward

26
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

for one bit

and this
number
could be
set to 0
Switch
between
Baud the
different
baud rates Click the
Switch correspo
Set between nding
Verify
COM none, odd, button on
even the
Status On/Off screen to
Bits 8 realize
Return to the
Exit the setting correspo
interface nding
Auto-print function
after
Printe Print
calibration
r
or test
Cancel Do not

27
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

print after
calibration
or test
Return to
Exit the setting
interface
ASP+ Increase or
decrease
the
ASP-
aspiration
Set Click the
volume
Vol correspo
Return to
nding
the
Exit button on
maintain
the
Maint interface
screen to
ain Deprot De-protein
realize
ein cleaning
the
Auto clean
correspo
the tubes
Clean Tube nding
with
ing function
reagent A
Return to
Exit the
maintenan

28
 Chapter 4 Interface Structure and Operation

First Second Third Fourth Fifth

Main level level level level level Achieved
Operation
menu sub- sub- sub- sub- sub- function
menu menu menu menu menu

ce
interface
Sampli Aspirate
ng sample
Auto
STD A aspirate
STD A
Auto
ADC STD B aspirate
STD B
Return to
the
Exit maintenan
ce
interface
Feed
Feed paper to
the printer
Return to
Exit the main
interface

29
 Chapter 4 Interface Structure and Operation

Note:
All the “Exit” operation or hearing the alarm sound, the
sample tubes and human body should stay away from
the probe and other moving parts, otherwise, it may
cause body injury or instrument damage.

4.2 Start up procedures and precautions

 After starting up, the instrument performs initialization and self-test,

please pay attention to the prompt message, and judge whether it
affects normal test.

 Instrument self-test will aspirate reagent to clean the tubes. During

this period, please observe the liquid flowing status and judge
whether there is any abnormal phenomena, like blockage or
leakage, etc.. After cleaning, it enters into the countdown interface
for selecting auto calibration or not, and automatically starts the
calibration procedure after 8 seconds, the results are displayed, as
shown in Fig. 4.1:

Fig. 4.1

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 Chapter 4 Interface Structure and Operation

 The potential millivolt values of STD A&B are displayed on the

screen in a sequence.

 The instrument automatically calibrates the slope and intercept of

STD A&B.

 After calibration, the system automatically prints the calibration

results, and enters into the main menu and performs other
operations.

4.3 Auto calibration

The instrument automatically performs calibration procedures when

starting up, in standby mode for more than one hour, continuously
testing for more than 30 times or replacing new reagents. The normal
calibration takes about 3 minutes at a time.

Perform auto calibration according to the following processes:

The instrument enters into the calibration interface to do auto

calibration, as shown in Fig 4.2.

Fig. 4.2

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 Chapter 4 Interface Structure and Operation

The calibrating results of ions are displayed after finishing the

calibration, as shown in Fig. 4.3, if there is any abnormal, it will be
displayed directly.

Fig. 4.3

The interface of Fig.4.3 will stay for 5s on the screen and automatically
print out, then the system enters into the main interface. If there is any
abnormal, recalibrate or take other measures according to the actual
situation.

Note:

The printed calibration data shows "Pass", means

calibration passed; "Error" means calibration abnormal.
Calibration abnormal will affect the test results!

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 Chapter 4 Interface Structure and Operation

4.4 Measure
4.4.1 Measuring flow chart

Turn on

Selt-test

Auto-
Calibrate

Main Menu

Measure

Prepare
sample

ASP

Take away
sample
Result and
print

Cancel Next

Main Menu

Other
operations

4.4.2 Sample test

In the main interface (see Fig. 4.4), click "Measure" to enter into the
measurement interface.

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 Chapter 4 Interface Structure and Operation

Fig. 4.4

Select sample type as shown in Fig. 4.5. After selecting the sample,
the sample probe automatically lifts from the suction tank and the liquid
system drains. Then the system enters into the measurement interface,
as shown in Fig. 4.6, in this interface, the barcode reader can scan to
input the 13-digit ID number (Refer to App. 7 for the detailed setting
methods).

Fig. 4.5

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 Chapter 4 Interface Structure and Operation

Click “Sampling” as shown in Fig. 4.6, when hearing a “di” alarm sound,
remove the sample immediately.

The probe returns to the aspiration position, the system auto

completes the test and displays the results on the interface, as shown
in Fig. 4.6.

Fig. 4.6

The instrument will auto-print the results. If “Cancel” is set for print
setting or need re-print, it needs to be printed manually, enter into the
“Result” interface, search the results to be printed and click “Print” to
print again. Click “Exit” to return to the measurement interface, see Fig.
4.6.

The probe lifts from the suction tank, click “Sampling” to enter step 3)
to complete all the sample tests of the same type.

Click “Exit” to do other menus’ operation.

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 Chapter 4 Interface Structure and Operation

Shutdown: turn off the power directly.

4.4.3 Sample test precautions

While in operation, like calibration or testing samples, make sure the

electrodes are soaked in the solution (the sampling volume could be
changed through the “Set Vol”).

After 30 tests, the system will auto prompt re-calibration or not,

re-calibration is required.

When in standby mode for more than 60min, re-calibration is required.

Please use this instrument between 15℃ to 30℃, if the temperature is

lower than 12℃, the test results may be affected due to the electrodes
activity decrease.
+ + - 2+ +
Possible reasons for K , Na , Cl , Ca (Li ), PH test data unstable or
drifting while in calibration: the solution did not immerse the electrodes;
liquid system blocked, need cleaning the tubes and electrodes, need
replacing the pump tube; reagents A, B used up and need to be
replaced; ground cable not appropriately connected and needs to be
reconnected; power supply burn-in and needs to be replaced;
reference electrode needs to be replaced.

The test value is high or slope is low: use the cleaning solution to clean
the electrodes, then the electrode activating solution to activate the
electrodes, please refer to 4.9.3.

Long time not use the electrodes, use the distilled water to wash away
the residual liquid of the electrode membrane tube, then seal and store
it wetly.

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 Chapter 4 Interface Structure and Operation

Only the medical staff trained by engineers from the manufacturer is

allowed to operate the instrument. If not follow this manual to operate
the instrument, the provided protection may be damaged.

Protective gloves should be worn while in operation; all the operations

should be regarded as contaminative or infectious.

The wastes and waste liquid should be disposed according to the

relevant national law and regulation, as well as the relevant
requirements of local environmental protection department.

Long time not use or move, the reagents should be taken out and the
tubes drained.

Devices connected with this electrolyte analyzer for data

communication should conform to the requirements in National
Standard GB 4793, GB4943 and IEC60950 of China;

When test urine or other non-serum body fluids, if need dilution, please
follow the related standards.

4.5 Calibration

The analyzer will do the calibration before the test to get the slope and
intercept.

Click “Calibrate” in the main menu, as shown in Fig. 4.4.

The analyzer will do the auto-calibration, as shown in Fig 4.2 and 4.3,
and will auto print the calibration result.

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 Chapter 4 Interface Structure and Operation

4.6 Correction

After the auto calibration, the instrument will generate a factor. While
doing the clinical tests, users are suggested to buy the human
substrate calibrators with traceability for results correction.

In the main menu, click “Correct” button.

Enter into the sample type selection interface, directly click to select
the sample type.

Enter into the interface of Fig. 4.7.

Fig. 4.7

Carefully check whether the ions’ target value is consistent with the
calibrators’ nominal value, if not, revise the target value to be the same
with the nominal value before re-correcting.

Change the target value: if the target value is not the same as the

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 Chapter 4 Interface Structure and Operation

calibrator’s nominal value, directly click the item, for example, if the
displayed target value for “K” is different from the nominal value,
directly click “K” in the interface of Fig. 4.7 to enter into the modification
interface, as shown in Fig. 4.8, directly click the corresponding
numbers to edit the result target value, then click “Enter” to save and
return to the interface of Fig. 4.7.

Fig. 4.8

Note:
The displayed target value on the interface must be
exactly the same with the calibrator’s nominal value.
Otherwise it will not be able to obtain reliable test
results after correction.

Auto correction

Click “Automatic” in the interface of Fig. 4.7 to do the auto-correction

(see Fig. 4.9). The probe will automatically lift up.

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 Chapter 4 Interface Structure and Operation

Fig. 4.9

Prepare the calibrator and put it under the probe, click “Sampling”, the
instrument automatically aspirates sample and displays the test value
and correction ratio, as shown in Fig. 4.10.

Fig. 4.10

After auto-correction, the instrument factor is auto-changed. Click

“Exit” to return to the correction interface, as shown in Fig.4.7.

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 Chapter 4 Interface Structure and Operation

Manual correction

If there is big discrepancy between the test results and the calibrator
result, click “Manual” in the interface of Fig. 4.7 to modify the
corresponding factor, the manual correction interface is as shown in
Fig. 4.11.

Fig. 4.11

Modify a value and b value according to the formula: y=ax + b, among

which: “y” stands for the corrected test results, “a” is the slope, “b” is
the intercept, and “x” is the actual test result. In Fig. 4.11, “1.000” is the
a value, “0.00” is the b value, “+”, “-” means the intercept positive or
negative.

If need to modify the slope and intercept of item “K”, click the
correspondingly a and b box to make the modification, as shown in Fig.
4.12, directly input the corresponding number, then click “Enter” to
save and return to the manual correction interface.

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 Chapter 4 Interface Structure and Operation

Fig. 4.12

After completing the factor modification for all ions, click “Exit” to return
to the correction interface of Fig. 4.7.

Click “Reset”, the modified factors will restore to the original value:
a=1.000, b=0.

Click “Exit” to return to the main menu.

4.7 Quality Control (QC)

In the main menu, click “QC” to select the sample type, as shown in
Fig.4.5.

After selecting the “Type”; it pops out a new interface, as shown in Fig.
4.13.

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 Chapter 4 Interface Structure and Operation

Fig. 4.13

Select one QC mode in Fig. 4.13 to enter the new interface, as shown
in Fig. 4.14.

Fig. 4.14

Measure

Click “Measure”, the probe will lift from the suction tank, and the
system enters into the interface of Fig.4.15.

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 Chapter 4 Interface Structure and Operation

Fig. 4.15

Put the QC solution under the probe, click “Sampling” to aspirate the
QC sample. After hearing a “di” alarm sound, remove the QC sample.

The probe returns to the aspirating position, after the auto-test, it

displays the results on the interface.

The instrument will auto-print the results. If “Cancel” is set for print
setting or need re-print, it needs to be printed manually, enter into the
“Result” interface, search the results to be printed, and click “Print” to
print again. Click “Exit” to return to the interface of Fig. 4.15.

Click “Exit”, the probe descends to the suction tank, and the system
returns to the interface of Fig. 4.14.

Lot No.

In the interface of Fig.4.14, click “Lot No.” to enter the interface of

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 Chapter 4 Interface Structure and Operation

Fig.4.16.

Fig. 4.16

Directly click the corresponding numeric key to input the lot No..

Click “Exit” to return to the interface of Fig. 4.14.

Statistics: click “Stat” to calculate the tested QC sample standard

deviation (SD) and coefficient of variation (CV).

Exit: click “Exit” to return to the main interface successively.

4.8 Setting

In the main menu, click “Settings” to enter into the setting interface of
Fig. 4.17, where you can set the Contrast, Units, REF STD, Time,
COM and Printer.

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 Chapter 4 Interface Structure and Operation

Fig. 4.17

4.8.1 Contrast

Click “Contrast” to set the contrast, as shown in Fig. 4.18.

Fig. 4.18

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 Chapter 4 Interface Structure and Operation

4.8.2 Unit selection

Click “Units” to enter the unit selection interface, as shown in Fig. 4.19.

Fig. 4.19

Directly select one unit, the results will do the auto-conversion. After
switching the units, the reference range needs to be re-input, set the
range according to the setting method in 4.8.3.

4.8.3 Reference range

Click “REF STD” to enter into the interface of Fig. 4.5, and select the
sample type.

After selecting one of the sample types, enter into the interface of Fig.
4.20.

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 Chapter 4 Interface Structure and Operation

Fig. 4.20

Select the item to be modified, the left side value is the lower limit and
the right side value is the upper limit. Directly click the upper or lower
limits of the corresponding item to enter into the interface of Fig. 4.16.
Click the numeric keys to input the upper or lower limit value, and click
“Exit” to return to the interface of Fig. 4.20.

Follow this procedure to complete the upper and lower limit of

reference values for all testing items.

Click “Exit” to return to the interface of Fig. 4.17, and click “REF STD”
to select different sample type, then follow step 4.8.3.2 to 4.8.3.4 to
input the “REF STD” for testing items of all the sample types.

The conversion method of mmol/L and mg/dL is as follows:

K: 1mmol/L=3.90983mg/dL

Na: 1mmol/L=2.29897mg/dL

Cl: 1mmol/L=3.54532mg/dL

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 Chapter 4 Interface Structure and Operation

Ca: 1mmol/L=4.00784mg/dL.

4.8.4 Date and time

In the setting interface, click “Set Time” button to enter into the
interface of Fig. 4.21.

Fig. 4.21

Click the left or right arrow key to select the date or time, if the cursor
selects one number, it is highlighted, directly input the corresponding
number to do the modification, after inputting the number, the cursor
automatically moves to the next number. Complete all the date and
time modifications successively.

After the modifications, click “Enter” to save and exit, then return to the
setting interface.

4.8.5 COM setting

In the setting interface, click “Set COM” to enter into the interface of Fig.

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 Chapter 4 Interface Structure and Operation

4.22 and set the communication mode, etc.

Fig. 4.22

Baud rate: click “Baud” to switch between the baud rates. The factory
default setting is 9600. Customers are not suggested to modify it by
themselves.

Parity check: click “Verify” to switch the verification mode between

Even, Odd or None. The factory default setting is “None”. Customers
are not suggested to modify it by themselves.

COM Status: click “Status” to set it “On” or “Off”. If need to be

connected with the hospital laboratory information system (LIS), the
COM status must be on.

Bits: they are fixed, can’t be modified.

Exit: click “Exit” to return to the setting interface.

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 Chapter 4 Interface Structure and Operation

4.8.6 Printer setting

In the setting interface, click “Printer” to enter into the interface of Fig.
4.23 to set the print mode.

Fig. 4.23

Directly click “Print” or “Cancel” to select the print mode. If select “Print”,
the printer will automatically print after the sample test or calibration, if
select “Cancel”, the printer will not print the results.

Exit: click “Exit” to return to the setting interface.

4.8.7 Test item setting

In the setting interface, click “Set Test” to enter into the interface of Fig.
4.24 to select the items to be tested.

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 Chapter 4 Interface Structure and Operation

Fig. 4.24

Exit: click “Exit” to save and return to the setting interface.

4.8.8 Exit

In the setting interface, click “Exit” to return to the main menu.

4.9 Maintenance

In the main interface, click “Maintain” to enter into the maintenance

interface of Fig. 4.25 to do the maintenance.

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 Chapter 4 Interface Structure and Operation

Fig. 4.25

4.9.1 Sampling adjustment

If the sampling volume is not enough or overmuch to fill in the whole

electrodes, it can be adjusted through “Set Vol”, the specific steps are
as follows:

In the maintenance interface, click "Set Vol" to enter into the interface
of Fig. 4.26.

Click the "5000" button after the “Sample” to change the sample
volume.

Click the "5000" button after the "Sam step" to adjust the steps
between the sample and the electrodes.

Click the "5000" button after the "Cleaning" to change the volume of
the cleaning solution.

Click the "5000" button after the "A/B" to change the STD A/B volume.

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 Chapter 4 Interface Structure and Operation

Click the "5000" button after the "A/B step" to adjust the steps between
the STD A/B and the electrodes.

Exit: click “Exit” to save the adjustment and return to the “Maintain”
interface

Fig. 4.26

4.9.2 Instrument cleaning

This function is for enhanced cleaning of the liquid system and

electrodes. In the maintenance interface, click “Cleaning” to enter into
the interface of Fig. 4.28, the cleaning is divided into “Deprotein” and
“Tube”, respectively described as follows:

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 Chapter 4 Interface Structure and Operation

Fig. 4.27

Deprotein

When used for a period of time, the slope value and stability of the
electrode will decrease. Perform this function to activate the electrodes
with activating solution to increase the electrode slope value and
enhance stability.

4.9.2.1.1 In the cleaning interface, put about 1mL deprotein solution or

other dedicated cleaning solution under the probe, click “Deprotein”,
the instrument automatically aspirates the cleaning solution, when
hearing the alarm sound, remove the cleaning solution.

4.9.2.1.2 When the probe descends to the suction tank, the instrument
follows the specified program to wash the whole liquid system
automatically. The working status will be displayed on the left side.

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 Chapter 4 Interface Structure and Operation

Tube

4.9.2.2.1 In the cleaning interface, put the 20mL dedicated cleaning

solution under the probe, click “Tube”, the instrument automatically
aspirates the cleaning solution to wash the tubes and displays the
working status on the left side, when hearing the alarm sound, remove
the cleaning solution.

4.9.2.2.2 The probe descends to the suction tank, and the tubes are
drained.

Exit: after cleaning, click “Exit” to return to the “Maintain” interface.

4.9.3 Potential track

Display each electrode’s mV value (potential millivolt value), this is

mainly used by service personnel. In the “Maintain” interface, click
“ADC” to enter the potential track interface of Fig. 4.28.

Fig. 4.28

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 Chapter 4 Interface Structure and Operation

Click “STD A” or “STD B”, the probe descends to the suction tank and
aspirates the corresponding liquid to measure the mV value according
to the specified program.

Sampling: put the sample (STD A, STD B or other dedicated solution)

under the probe, click “Sampling” to aspirate the specified volume,
when hearing the alarm sound, remove the sample and test the mV
value according to the specified program.

Exit: click “Exit”, the probe descends to the suction tank, and the
system returns to the “Maintain” interface.

4.9.4 Feed

When replacing the print paper, use the “Feed” function to easily install
the print paper, the specific operation is as follows:

Take out the print paper from the printer and put in new paper.

In the “Maintain” interface, click “Feed” to automatically feed paper.

4.9.5 Exit

Click “Exit” to return to the main menu interface.

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 Chapter 5 Maintenance and Service

Chapter 5 Maintenance and Service

In order to get a good performance of this analyzer, ensure its stability

and extend its lifetime, please strictly follow this chapter to do
maintenance and service for this instrument and electrodes.

5.1 Tools Preparation

Stainless steel wire (diameter ≤ 0.6mm, hole-unclog needle)

Plastic syringe (about 5ml, without needle)

Soft tissue

Clean gauze

Clean cotton swab

Non-ionic surfactant cleaning fluid

84 disinfectant

Medical latex gloves

5.2 Daily maintenance

(1) Clean the outside of the probe

If not clean the outside of the sample probe after testing serum, the
residual serum will flow down and finally gathered in the needle mouth
to slowly desiccate, it may block the probe after a long period of time,
which makes it unable to perform calibration and measurement. So
remember to clean the outside of the probe with soft tissues (cannot

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 Chapter 5 Maintenance and Service

use cotton or gauze) after finishing each batch of measurement.

Please follow the steps below to do the cleaning:

→“Cleaning” to
In the main menu interface, click “Maintain”
1
lift the probe from the suction tank;
Gently wipe the needle tip with soft tissue until there are no
2
visible attachments.

(2) Wipe the analyzer table-board

The spattered serum and other substances on the table-board should

be cleaned in time, after the daily use, turn off the instrument and take
the following steps to do the cleaning:

Use a wet towel stained with cleaning solution to wipe the

1
analyzer table-board, until all the stains are wiped off;
Use a wet towel stained with disinfectant to wipe the
2
analyzer table-board;
Fifteen minutes later, wring the clean wet towel to wipe the
3
analyzer table-board and remove the remaining disinfectant;
Gently wipe the suction tank area with a clean gauze until
4
there are no visible attachments, such as dust, etc.

Note: Corrosion
Cleaning solution is chemical corrosive, protective
gloves should be worn while in operation.

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 Chapter 5 Maintenance and Service

Note: Biological contamination

Table-board should be regarded as contagious,
protective gloves should be worn while in operation.

(3) Check the waste bottle

The waste tube and its interface are located at the right side of the
analyzer, check the waste tube and waste bottle in the following order:

Check whether the waste tube is twisted or not, if twisted,

1
straighten it out;
Check for leaks or overflow of the waste bottle, if there is
2 leakage, replace the waste bottle, if overflow, drain the
waste bottle.

(4) Check peristaltic pump tubes and other tube connectors

Open the front door of the analyzer, the peristaltic pump tube is located
at the downside, check the pump tubes in the following order:

Check for leaks or crack of the pump tube, if there is any

1 leakage, re-connect or replace the tube, if crack, replace
the tube;
Check whether the pump tube falls off, if it is off, please
2
re-connect it.
Check all the tube connectors, observing if there is
3
leakage or looseness.

(5) Check the electrode filling solution

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 Chapter 5 Maintenance and Service

Check the filling solution volume of each electrode, if lack of the filling
solution, it will greatly affect the test results, please refer to App. 4 for
the specific maintenance method.

5.3 Weekly Maintenance

5.3.1 Check the electrodes at least once a week, clean the dried
solution and sample, and keep the measuring electrode clean.

5.3.2 Check the filling solution volume of the electrodes. Make sure the
Ag/AgCl reference electrode is always immersed in the filling solution.
If the reference electrode filling solution is used too much, add the
filling solution by the syringe or replace the filling solution. Refer to App.
4 for the specific methods.

5.3.3 Immerse the electrodes into the deprotein solution for 5 minutes
to guarantee the electrodes’ state (refer to the bottle label for the usage
of the deprotein).

5.4 Unscheduled Maintenance

5.4.1 Blocking: if the probe is clogged, use the hole-unclog needle

supplied with the instrument to unclog the probe while the probe is lift.

5.4.2 In order to make the probe and tubes play its good function,
make sure their inner surface is clean and smooth. Perform the
maintenance and service as required. It is recommended to do
maintenance at least once a month. If there is protein residue at the
inner surface of the tubes, follow the steps in the table below to do the
cleaning:

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 Chapter 5 Maintenance and Service

In the main menu interface, click “Maintain”→“Cleaning” to lift

1
the probe from the suction tank;
Turn off the power, then pull out the power cord from the
2
instrument;
3 Take a plastic tube and place it under the probe;
Take a 5ml syringe to aspirate appropriate amount of 5%
4
NaClO solution;
Remove “Tube 1” from the left side of the electrode module,
5 and connect it with the syringe, then slowly inject the solution
into the tube, the liquid will come out from the probe tip;
6 Repeat step 4 & 5 1-2 times;
Replace the 5% NaClO solution with the distilled water, and
7
repeat step 4 & 5;
Remove the plastic tube from the probe; (Note: otherwise it
8
may cause probe damage!)
Tightly connect “Tube 1” with the left side of the electrode
9
module;
→“Cleaning” in the main
Turn on the power, click “Maintain”
10
menu;
Remove “Tube 2” from the right side of the electrode module,
11
and put it into the 5% NaClO solution;
Click “Cleaning”, the instrument automatically aspirates 5%
12
NaClO solution;
13 Repeat step 12 1-2 times;
Replace 5% NaClO solution with distilled water, and repeat
14
step 12;
Tightly connect “Tube 2” with the right side of the electrode
15
module.

62
 Chapter 6 Problems and Troubleshooting

Chapter 6 Problems and Troubleshooting

6.1 Circuit and detection system

Error Possible reasons Solutions
Power switch off Turn on the switch
No power supply Re-plug the power socket
No display
Display signal lines
Re-plug the display cable
loose
Display Display contrast of the Enter into the contrast
fuzzy or too LCD screen changed interface to adjust the contrast
deep with the environment of the instrument
No paper Replace the new paper
Paper stuck after
Clear the paper jam area
tearing off the paper
Printer not
Thermal print paper
working Re-install the paper
mounted inversely
Printer interface cable Re-connect the printer
loose interface cable
Reference electrode Replace the reference
failure electrode
Reference electrode
Add reference electrode filling
mV value filling solution
solution
display inadequate
abnormal Electrode cable Check the electrode cable
connected improperly connection
Whether the AD Test the AD module to check
module works whether it works normally or

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 Chapter 6 Problems and Troubleshooting

Error Possible reasons Solutions

normally or not not
Check whether the liquid
Do not aspirate STD system, distribution valve,
A/B or aspiration peristaltic pump, and liquid
volume is not enough system sensor work normally
or not
Check whether the liquid
The sample or
system, liquid system sensor
standard solution not
is normal or not, and the
reached the
tested liquid is fully filled the
designated position
electrode
Data test Reagents used out or
abnormal Replace the reagents
deteriorated
Reference electrode Replace the filling solution of
or the measuring ion the reference electrode or ion
electrodes not good electrodes

Bad grounding Re-connect the ground cable

Test data too

Correction factor Restore the correction factor
big or too
values abnormal value to its original value 1.00
small

If the problems are not solved or there are other problems, please
contact the after-sales service unit.

6.2 Liquid system

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 Chapter 6 Problems and Troubleshooting

Possible
Error Solutions
reasons
Pump tube Replace with a new pump
damaged tube
Check whether the pipeline
Pipeline clogged
clogged or leaking
Not aspirate sample
Peristaltic pump Pump tube too tight or the
not working motor damaged
Pump tube too Replace a pump tube with
long an appropriate length
Distribution Replace with a new
valve positioning distribution valve positioning
sensor failure sensor
Distribution Replace with a new
valve shaft distribution valve shaft,
failure or check whether the valve is
Not aspirate STD
clogged clogged or not
A/B
The aspiration
position Replace with a new suction
seriously tank
abraded
Pipeline clogged Check whether the pipeline
or air leaking is clogged or leaking
Switch to manually adjust
Inadequate sample Liquid sensor the sampling mode to check
filling the electrodes failure if need to replace the liquid
leads to abnormity sensor or liquid tube
Inadequate Increase the sample

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 Chapter 6 Problems and Troubleshooting

sample aspiration volume

aspiration
Observe whether the liquid
Peristaltic pump stops at one side of the
too loose or too pipeline to determine
tight whether the pump tube
needs to be replaced
Pump tube is too Replace a pump tube with
tight or too short an appropriate length
Peristaltic pump not
Please contact the
working
Motor damaged manufacturer or its
distributors
Air leakage or There is leakage at the front
Homogeneous and
the O ring of the connector where there are
continuous bubbles
distribution valve bubbles, replace the
inside the pipeline
abrasion connector and O ring
Check the failure reason,
use the deprotein solution to
Single electrode soak the electrodes, or
Electrode failure
data abnormal replace with the new
electrodes and add filling
solution

If the problems are not solved or there are other problems, please
contact the after-sales service unit.

6.3 Instrument alarm and handling

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 Chapter 6 Problems and Troubleshooting

Alarm Possible reasons Solutions

Re-aspirate sample. Observe

Aspirated too whether the sampling is normal
Please many bubbles, or not, if normal, refer to liquid
re-aspirate bubble sensor not system positioning of 4.9 to try
the sample working, liquid the manual positioning. If
system failure, etc. abnormal, check the liquid
system.
Didn’t calibrate
Please after reaching the
Re-calibrate
Calibrate specified times or
time.
Please The remaining
Replace with the matched
replace the reagent is small or
reagents
reagents used up
Please If still not working after replacing
Print paper used
replace the the print paper, please contact
up or printer failure
print paper the service department
Re-calibrate, observe whether
Liquid system
Please check the liquid flows normally or not, if
abnormal or
the liquid normal, try the liquid system
positioning sensor
system or positioning function of 4.9, if
disabled while in
sensor abnormal, maybe the liquid
calibration
system has failure
The trial The machine
Contact the supplier
mode expired works in trial mode

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 Chapter 6 Problems and Troubleshooting

6.4 Parts or consumables that can be replaced by

customers

6.4.1 Print paper: Please refer to App. 1.

6.4.2 Matched reagents: Please refer to App. 2.

6.4.3 Peristaltic pump tube: Please refer to App. 3.

6.4.4 Electrodes: Please refer to App. 4.

6.4.5 Electrode filling solution: Please refer to App. 5.

6.5 Parts need to be replaced by service engineers

Main power switch

Fuse, model F3AL250V

Sampling probe

Motor

68
 Chapter 7 Common Consumables and Ordering Methods

Chapter 7 Common Consumables and

Ordering Methods

The following list is the electrolyte analyzer consumables needed for

daily operation or maintenance:

No. Name Specification

1 Printing paper 57mm×35mm
Select according to the test items,
please refer to the reagents instruction
2 Reagent
or contact the manufacturer or its local
distributors.
3 QC solution 50mL
4 Deprotein solution 250mL
5 Cleaning solution 250mL
PVC electrode
6 250mL
activating solution
Electrode filling
7 10mL
solution
Reference electrode
8 10mL
filling solution
9 K electrode Piece
10 Na electrode Piece
11 Cl electrode Piece
12 Ca electrode Piece

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No. Name Specification

13 Li electrode Piece
14 pH electrode Piece
15 Ref. electrode Piece
16 Fuse 3A, φ5mm×20mm
17 Pump tube 85mm, φ2mm×4mm
18 Tube φ1.5mm×0.8mm

Ordering methods:

1. Purchase from the local distributors.

2. Purchase from the manufacturer.

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 Chapter 8 Transportation, Storage and the Outer Packing Instructions

Chapter 8 Transportation, Storage and the

Outer Packing Instructions

8.1 Transportation and storage

8.1.1 Transportation

The instrument can be transported by general means of transport, but

it should avoid severe impact, vibration and splashing of rain or snow.
Transportation requirements should comply with the order contract.

8.1.2 Storage

The packaged analyzer should be stored indoor at a room temperature

between 0 ℃ to 40 ℃ , with relative humidity less than 80%,
non-corrosive gases and good ventilation.

8.2 The outer packing instructions

—— “Up”: Make sure the instrument is always upwards.

—— “Fragile”: Be careful when moving the packing box.

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 Chapter 8 Transportation, Storage and the Outer Packing Instructions

—— “Rain-proof”: It is strictly prohibited to the rain.

—— “Layer limit”: The maximum number of stacking

layer of the same package is 3.

—— “Ambient humidity”: The storage ambient

humidity should be 0%-90%.

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 Chapter 8 Transportation, Storage and the Outer Packing Instructions

—— “Temperature limit”: The storage temperature

should be 0℃-40℃.

Pictures are for reference only, please refer to the actual pictures on
the real packing box.

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 Chapter 9 Appendix

Chapter 9 Appendix

9.1 Print paper replacing method

Open the printer cover and take down the roller (take it out horizontally
with care), then take out the remaining paper.

1) Put the paper roll into the feed slot, pay attention to the different
side of the thermal print paper, and make sure the thermal side is
downward. Then put the paper under the printer roller, make sure
the print paper trend is vertical to the printer roller. (In order to
avoid paper jam while printing). Please refer to Fig. 9.1.1

Fig. 9.1.1

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While installing the printer roller, align the gear side first, then lay flat
the roller and click it to the right position.

2) Click “Feed” to observe whether the feed is smooth and vertical to

the printer roller, if not correct, make an adjustment. When the
paper gets out of the printer cover, click “Feed” again to stop
feeding.

Pull out the paper and close the printer cover.

Note: In the main interface, click “Maintain” to select the “Feed”

function.

9.2 Reagent replacing method

The reagent room is located at the right side of the instrument. Open
the reagent room door to take out the old reagent.

Put in the new reagent, and insert the tube into the new reagent bottle,
notice that the letters on the tube should be consistent with the letters
on the bottle.

Make sure the tube end reaches the bottom of the reagent bottle.

Close the reagent room door.

9.3 Pump tube replacing method

Open the front panel of the instrument, in the lower right corner, there
are peristaltic pump, pump tube and tube connectors. Please refer to
Fig. 9.3.1.

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 Chapter 9 Appendix

Fig. 9.3.1

Take out the pump tube connectors from the baffle plate to remove the
pump tube.

Pull out the connectors connected with the pump tube.

Get one new pump tube and install it in reverse order.

Close the front panel.

9.4 Electrode replacing method

Open the front panel of the instrument, there are aligned electrodes,
such as K, Na, etc.. Please refer to Fig. 9.4.1.

Disassemble the electrode connectors, tube 1 and tube 2 from the

corresponding interface.

Take out the electrode module: Uplift the electrode module from the
slot to take out the whole electrode module.

Take out the electrodes: Loose the left and right spinning nut of

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 Chapter 9 Appendix

electrodes to take out the electrodes.

Fig. 9.4.1

Electrode installation: Before installing the electrodes, use the fingers

to flick the electrodes, making the bubbles floating at the top of the
electrodes (the copper contact terminal is the top of the electrode).
Notice that the installation sequence should be the same with the
marked sequence at the electrode connector interfaces and the seal
ring should be installed between the electrodes, refer to Fig. 9.4.1.
Make the electrode contact terminal downward and electrode
connector upward to install the electrodes.

After installing all electrodes, tighten the left and right spinning nuts of
the electrode module.

Put the electrode module into the slot, and connect the connectors with
tubes. Notice that the electrode connectors should be consistent with
the interface symbols;

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After replacing the electrodes, they are needed to be activated. Follow

the instructions of 4.9.3.1 in Chapter 4 to activate the electrodes with
activating solution for at least 5 times.

9.5 Instructions for ISE

9.5.1 Components of ISE

The ISE consists of ion selective membrane, electrode body, Ag/AgCl

inner electrode, electrode filling solution and the seal ring (see Fig.
9.5.1).

Note: Pictures are for reference only, please see the real product for
detailed information.

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 Chapter 9 Appendix

9.5.2 Electrode filling

The electrodes must be filled with filling solution before use and the
dedicated syringe needle (the metal part is 8-10mm in length) is
needed to add in the filling solution to avoid poking the electrode
membrane. The electrode chamber should be filled with 2/3 to 3/4
filling solution (see Fig. 9.5.2), then tighten the conductive pole, make
sure there are no bubbles between the filling solution and the
membrane. Clean and dry the electrode surface and install them
according to the electrode order.

9.5.3 Electrode service and maintenance

The newly installed electrodes must be activated by fresh QC serum or

fresh serum for more than 2 hours.

While the electrode is in use, there will be pollution, poisoning and the
filling solution reducing, etc., reflected by the abnormal electrode drift
and electrode response (including electrode mV value abnormal and
electrode mV difference value abnormal). For the electrode pollution,
use the deprotein solution to clean the contaminant attached on the
electrode membrane, if seriously polluted, use the cotton thread to
clean the attachments by pulling it back and forth inside the electrode
hole (all the electrodes are strictly prohibited using hard object to poke).
If the filling solution decreased, toss out the remaining solution, then
refill with new filling solution.

If the mV value is abnormal or drifting, use fresh QC serum or fresh

serum to activate the electrode for more than 2 hours until the
electrodes are stable.

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 Chapter 9 Appendix

9.5.4 Electrode storage

The electrode should be stored between 2℃~8℃ and avoid direct

sunlight and freeze.

Note: The electrode number is one of the electrode’s warranty

evidences. Please take good care of it for future queries.

9.6 MSCOMM

Hardware conditions: Connect two communicating instruments’

RS-232C interface through a RS-232C cable, or connect the
instrument with one PC’s COM interface. The optional serial port status
for this analyzer:

Connection: To exchange data with a PC, use a standard RS-232

serial port line to connect with the COM RS232 1 on the back of the
instrument, and connect the other end to the serial port on the back of
the PC.

Take the following steps to do the settings:

Baud rate: 115200, 57600, 38400, 19200, 9600;

Parity check: odd, even, none;

Working status: send, receive, duplex;

Transmit frame format:

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 Chapter 9 Appendix

The data information for one item

Byte Type Code

1 Frame header 02
1 Version 1
1 Instrument type 3
1 Instrument No. 0
12 Time ASCII 0-9
1 Sample type ASCII 0-3
5 No. ASCII 0-99999
13 ID ASCII 13 digits
1 Item name ASCII: K, Na, Cl, iCa, TCa, pH
3 Integer data ASCII 0-999
1 Decimal point ASCII .
2 Decimal data ASCII 0-99
3 Unit ASCII: mmol/L, mg/dL
1 Frame tail 03

Item name code:

No. Name Code No. Name Code

1 K ASCII K 5 TCa ASCII TCa
2 Na ASCII Na 6 Li ASCII Li
3 Cl ASCII Cl 7 PH ASCII pH
4 iCa ASCII iCa

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Unit code:

No. Name Code No. Name Code

0 mmol/L ASCII mmol/L
1 mg/dL ASCII mg/dL

Sample type code:

No. Name Code

0 Serum 30H
1 Urine 31H
2 CSF 32H
3 Others 33H

Serial port communication explanation:

1) There may be multiple items in the frame. The item quantity is

determined by the instrument type and the ions to be tested.

2) All the sending data is ASCII code, if using serial port tool, switch
to the character format.

3) Each item name or data should be separated by at least one

space.

Typical frame analysis:

After testing one sample and QC sample, the instrument outputs a

string of character data through the RS-232 port, as shown below:

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Sample test:

1 3 0 201107062007 0 No 00007 ID 0000000000000 K 25.84

mg/dL Na 301.8 mg/dL Cl 317.6 mg/dL iCa 6.53 mg/dL
TCa 12.73 mg/dL pH 7.36 mg/dL 

QC sample:

1 3 0 201107070858 0 No 00005 ID QC1 K 25.76 mg/dL Na

302.3 mg/dL Cl 318.0 mg/dL iCa 6.53 mg/dL TCa 12.73
mg/dL pH 7.37 mg/dL 

Analysis is as follows:

Frame header: 02H

Version: 1

Instrument type: 3

Instrument No.: 0 (Electrolyte Analyzer)

Test time: 201107062007 (on July 6th, 2011 at 20:07pm)

Sample type: 0 (Serum)

No.: 00007

ID: 0000000000000 (display QC No., such as QC1, for QC test)

Item information: K 25.84

Unit: mg/dL

Frame tail: 03H

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 Chapter 9 Appendix

9.7 Barcode reader settings

Hardware conditions: Connect barcode reader of the serial port type

(other interfaces are not supported) with COM RS232 2 of the analyzer.
The ninth pin of COM RS232 2 supplies +5V voltage. The barcode
reader does not need external power supply. The following setting is
used for the XS-6500 barcode reader of “XINGSHENG” brand. For
other brands of barcode reader, please refer to the specific setting
manual.

Connect the barcode reader to the COM RS232 2, the reader will
prompt a “di” alarm sound.

Reset the barcode reader according to the provided instruction, as

follows:

Enter setting Restore factory setting Complete setting

Select the data port to serial port mode, as follows:

Enter setting Serial port mode Complete setting

Set the serial port mode to Baud rate: 9600, Parity: None, Data Bit: 8,
as follows:

Enter setting Baud rate: 9600 Parity: None Data bit: 8

Complete setting

After completing the settings, enter into the “Measure” interface of Fig.
4.6, use the barcode reader to scan a 13-digit barcode, after hearing a
“di” alarm sound, check whether the displayed ID No. is consistent with
the barcode to be input, if not, reset it again.

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Item No.: P01.91.300253-00