Data Extraction (LDH)

Adjusted OR
High LDH vs Low/Normal High LDH vs Low/Normal
Authors Complete LDH Cut- Unadjusted (95% CI) Adjusted
No Country Study Design Subjects LDH (Hypertensive LDH (Hypertensive NOS
(Year) Assessment Off Value OR (95% CI) (Low vs Variables
Retinopathy) (n) Retinopathy) (n)
High)
10. Bhandari, India Prospective 100 Pre- <600, 600- Maternal outcome Perinatal outcome
Nirmala et al cohort eclampsia 800, >800 Eclampsia Apgar 1 min <7
(2019) <600: 0 <600: 40/53
600-800: 3/27 600-800: 24/27
>800: 6/20 >800: 19/20

Abruption Apgar 5 min <7

<600: 5/53 <600: 7/53
600-800: 3/27 600-800: 4/27
>800: 6/20 >800: 6/20

HELLP syndrome LBW

<600: 0 <600: 21/53
600-800: 1/27 600-800: 18/27
>800: 4/20 >800: 17/20

DIC Prematurity
<600: <600: 18/53
600-800: 1/27 600-800: 9/27
>800: 2/20 >800: 6/20

Transfer to RICU/ICU VLBW

<600: 0 <600: 3/53
600-800: 3/27 600-800: 5/27
>800: 3/20 >800: 8/20

Renal failure Neonatal sepsis

<600: 0 <600: 2/53
600-800: 1/27 600-800: 2/27
>800: 2/20 >800: 5/20
 Mortality NICU admission
<600: 0 <600: 12/53
600-800: 0 600-800: 8/27
>800: 1/20 >800: 10/20

Perinatal mortality
<600: 4/53
600-800: 3/27
>800: 8/20
11. Dev, SV et al India Prospective 150 Pre- <600, 600- Maternal outcome Perinatal outcome
(2019) cohort eclampsia 800, >800 Abruption Still birth
and <600: 1/105 <600: 0
eclampsia 600-800: 2/27 600-800: 0
>800: 6/18 >800: 1/18

HELLP NICU admission

<600: 0 <600: 16/105
600-800: 3/27 600-800: 8/27
>800: 8/18 >800: 11/18

DIC Perinatal mortality

<600: 0 <600: 1/105
600-800: 0 600-800: 2/27
>800: 2/18 >800: 4/18

Renal failure
<600: 0
600-800: 0
>800: 1/18

Pulmonary edema
<600: 0
600-800: 0
>800: 1/18
12. Deshmukh, India Prospective 100 Pre- <600, 600- Neonatal outcome Maternal outcome
VL et al cohort eclampsia, 800, >800
(2020) eclampsia Apgar 5 min <7 HELLP
<600: 0 <600: 1/51
600-800: 3/22 600-800: 4/22
>800: 3/27 >800: 21/27

NICU admission PPH

<600: 13/51 <600: 6/51
600-800: 13/22 600-800: 6/22
>800: 7/27 >800: 12/27

LBW ARF
<600: 23/51 <600: 1/51
600-800: 15/22 600-800: 0
>800: 24/27 >800: 14/27

IUGR Abruptio placenta

<600: 4/51 <600: 3/51
600-800: 4/22 600-800: 4/22
>800: 6/27 >800: 18/27

IUFD DIC
<600: 5/51 <600: 2/51
600-800: 5/22 600-800: 4/22
>800: 18/27 >800: 19/27

Neonatal death ARDS

<600: 0 <600: 0
600-800: 2/22 600-800: 0
>800: 1/27 >800: 2/27

ARDS Pulmedema
<600: 2/51 <600: 0
600-800: 0 600-800: 0
>800: 1/27 >800: 6/27
Sepsis
<600: 0
600-800: 0
>800: 9/27

MODS
<600: 0
600-800: 0
>800: 6/27

Ventilator
<600: 1/51
600-800: 5/22
>800: 21/27

CVA
<600: 0
600-800: 0
>800: 5/27

Death
<600: 0
600-800: 0
>800: 5/27