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LEGEND

Factors contributing to the disease


Disease Process
Signs and Symptoms

Angina Pectoris

MODIFIABLE FACTORS NON-MODIFIABLE FACTORS


 High cholesterol diet  Age
 Obesity  Gender
 Cigarette smoking  Family history
 Sedentary lifestyle

Formation of Thrombus

Presence of Atherosclerosis

Eating heavy Exposure to cold, Physical


meals emotional stress, exertion
smoking

Blood flow in the Myocardial O2


mesenteric Vasoconstriction demand
region

Reduced coronary tissue perfusion

Myocardial oxygenation

Aerobic O2 demand
metabolism

HR accelerates
ATP
Lactic acid

Cardiac
Myocardium Vent. filling
Lactic contraction
becomes time
acidosis strength
ischemic

SV
Chest Depression of
Vent. perform
pain vent. function
deteriorates

Auto regulation SV
LV diastole
of blood flow or
pressure rise
compensation

Changes in
In diameter of systemic BP
Pulmonary
blood vessels congestion dyspnea
and arteries

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