Hyperlipidimea answer

1. HMG-COA-Reductase Inhibitor is
[ 3-hydroxy. 3- methyl Glutoryl COA Reductase inhibitor ]

2. Which of the following drug are withdrawn from the US market in 2001 due to increased
risk of myopathy and rhabdomyolysis?
A. Cerevastatin
B. Cisapride
C. Dexfenfluramine

3. Cerivastatin withdrawal from the market because it causes:

a- rhabdomyolysis
b- osteomylitis
c- leukemia
d- CNS Disturbances

4. Simvastatin is categorized by FDA as pregnancy category X this mean that

a- The drug is contraindicated during pregnancy
b- The drug affect the fetus to small extent
c- The drug should be used with caution during pregnancy
d- The drug is used in third trimester
e- The drug is absolutely safe to use

5. Which of the following HMG-CoA reductase inhibitors causes the greatest percentage
increase in HDL?
A. Simvastatin
B. Pravastatin
C. Lovastatin
D. Fluvastatin
E. All produce *****alent reductions

6. drug not decreases LDL:-

a)simvastatin
b) clobifibrate
c) nicotinamide

7. Which of the following medications cause Rhabdomyolysis?

a- Simvastatin
b- Sumatriptan
c-Phenytoin
d- Fusidic acid injection

8. (Simvastatin) it's trade name is

(a) Zocor®
(b) Amoxil®
(c) Mevacor®
(d) Lipitor®
(E) Ator®

9. (Cerivastatin) with drawn from saudi because mortal effect on

(a) Muscles
(b) Bone
 (c) Blood
(d) C.N.S
(E) Liver

10. Drugs for treatment hyperlipidemia

(a) lovastatin
(b) mebendazole
(c) lorazepam
(d) none of the above
(E) All of above

11. bile acid sequestrants: cholestyramine, colestipole, colesevemol

12. cholestyramine resin has the prevalent side effect of

a- Blocking absorption of some vitamins
b- Raising cholesterol levels
c- Causing intoxication
d- Increasing sensitivity to uv light
e- All of the above

13. (Questran)®it's generic name is

(a) Cholestyramine A
(b) Simvastatin
(c) Atrovastatin
(d) Niacin
(E) Clostipol

14. wich of the following is used to lower blood lipid levels?

A- trimethadione
B- colesevelam
C-flucytosine
D-coumarin
E- propranolol

15. Colestipol HCI is most commonly employed as a (an)

A) Antidote for atropine overdosage
B) Hypoglycemic agent
C) Bile acid sequestrant
D) Fat substi tute
E) Bronchodilator

16. what is the generic name of vitamin B3:

a-cyanocobalamin
b-niacin
c-riboflavin
d-pantothenic acid
e-pyridoxine
f-folic acid

17. The least stable of water soluble vitamins is

A) Ascorbic acid
B) Thiamine
C) Niacin
D) Folic acid

- Gimfibrazole for hyperlipidaemia

18. Gemfibrazile
a- Increase HDL & Triglycerides
b- Increase HDL & decrease Triglycerides
c- Decrease HDL & LDL
d- Increase LDL & Triglycerides.

19. clofibrate act as :-

1-decreas HDL
2-decreases lipoprotein lipase
3-synthesis of cholesterol
4-decreases lipoprotein

20. Which of the following is a lipid lowering drugs?

a- Aprotinin
b- Tranexamic acid
c- Lansoprazole
d- Acipimox