Hypercoagulable State Venous Stasis Vessel Injury

Ultrasound:
Body attempts to break Blood clot develops, (commonly in deep veins of the Presence of clot
down clot legs) = Deep Vein Thrombosis (95% of PE) in Deep Vein of
Leg

Fibrinogen breakdown
products in blood Clot dislodges, migrates to IVC → right atrium of
heart → right ventricle → lodges in pulmonary artery

PULMONARY EMBOLISM (PE)

↓ perfusion to lung parenchyma Thromboembolic blockage of pulmonary vasculature

Ischemia of lung tissue distal to clot Clot occludes pulmonary arteries

↑ dead space ventilation and V/Q ↓ Arterial O2

X-Ray: mismatching
Hampton’s Hump
Pleural based area
of ↑ Opacity
Chemoreceptors detect ↑ CO2 and ↓ O2

Pleuritic Chest Pain +

Dyspnea Signal brain to ↑ breathing rate Tachypnea