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The modified tunnel technique – options and indications for mucogingival


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Article  in  Journal de Parodontologie · January 2012

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Jamal M. STEIN1, 2
Christian HAMMÄCHER2

1- Department of Operative Dentistry,


Periodontology and Preventive Dentistry,
University Hospital Aachen, Aachen,
Germany

The modified tunnel 2- Clinic for Implantology, Periodontology


and Prosthodontics, Aachen, Germany

technique – options Accepted for publication:


15 september 2011

and indications The authors report no conflicts of


interest relevant to this publication.

for mucogingival therapy


Technique de tunnélisation
modifiée : options
et indications en chirurgie
muco-gingivale

RÉSUMÉ

ABSTRACT Différentes techniques ont été décrites pour recouvrir les


récessions gingivales et augmenter les tissus mous : lam-
Different methods for coverage of gingival recessions and beaux pédiculés et/ou greffes de tissu conjonctif. Parmi les
soft tissue augmentations using pedicle flaps and/or connec- techniques novatrices visant à augmenter la quantité de tissu
tive tissue grafts (CTG) have been reported. One of the inno- kératinisé, on trouve la celle de tunnélisation modifiée qui
vative techniques to increase the amount of keratinized tis- se définit comme étant un lambeau d’épaisseur partielle réa-
sue is the modified tunnel technique which is designed as lisé sans incisions de décharge. Contrairement à la technique
split flap without vertical releasing incisions. In contrast to d’origine, cette modification associe l’insertion d’une greffe
the original technique, the modification combines the inser- de tissu conjonctif avec un repositionnement plus coronaire
tion of a CTG with coronal advancement of the tunnel com- de l’ensemble de la zone tunnélisée. Cet article décrit les
plex. The present article describes the main characteristics principales caractéristiques et met l’accent sur les différentes
and highlights different indications and limitations for this indications et limites que présente cette technique. Un guide
technique. Depending on recession depth and the presence des indications en fonction de la profondeur de la récession
of keratinized tissue an indication guideline for decision et la présence ou non de tissu kératinisé est présenté pour
making is introduced. aider le clinicien dans sa prise de décision.

KEY WORDS MOTS CLÉS


Mucogingival surgery, recessions, modified tunnel technique. Chirurgie muco-gingivale, récessions, technique de tunnéli-
sation modifiée.

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The modified tunnel technique – options and indications for mucogingival therapy
Technique de tunnélisation modifiée : options et indications en chirurgie muco-gingivale

Introduction sions cor onally advanced flaps The modified


(CAF), connective tissue grafts (CTG) tunnel technique
Gingival recessions are defined as and guided tissue regeneration (GTR)
exposure of the root due to an api- can be used, however the amount According to the protocol of Allen
cal movement of the margo gingi- of root coverage with CTG was sta- (Allen, 1994), the design for the ori-
vae. Their prevalence seems to in- tistically superior to GTR (Roccuz- ginal tunnel technique comprises the
crease from 8% in children to 100% zo et al., 2002; Oates et al., 2003). preparation of a supraperiosteal mu-
in adults with an age of 50 years and Further, the combination of CAF with cosa flap with intrasulcular incisions.
more (Kassab and Cohen 2003; CTG showed a sign ificantly better This allows the mobilisation of the
Woofter, 1969). Etiologic factors percentage of coverage than CAF cervical gingiva and, ther efore, the
comprise primary morphogenetic alone (Cairo et al., 2008). Similar, the creation of a “pouch”. By undermi-
and secondary factors. Primary mor- use of biologic factors such as en- ning the inter dental papillae a mu-
phogenetic factors are the absence amel matrix derivatives (EMD) in ad- cogingival tunnel between all adja-
or dehiscence of buccal bone wall dition to the CAF significantly en- cent pouches can be developed.
(Lost, 1984) and/or a thin gingival hanced the clinical outcomes The subepithelial CTG is then inser-
biotype (Müller et al., 2000), while compared to CAF alone. Although ted into the tunnel, partly exposed
traumatic brushing (Serino et al., root coverage after CAF + CTG and over the recessions and sutured in
1994), inflammatory periodontal di- CAF + EMD did not significantly dif- this position. Since the amount of
sease (Wennström, 1996) or ortho- fer from each other (Cair o et al., root coverage is depending on the
dontic movement of teeth (Coatoam 2008), the amount of keratinized tis- size of the graft which survives over
et al., 1981) are secondary factors. sue was higher after the use of CAF the root surface, necrosis of the ex-
Plastic periodontal surgery offers se- + CTG compared to CAF + EMD posed parts of the CTG is one of the
veral options to tr eat and pr event (McGuire and Nunn, 2003). problems which limit the pr edicta-
periodontal recessions. According For treatment of multiple recessions bility of this original technique. T o
to the suggestions of Miller (Miller , and those with Miller class III only overcome this problem, a better co-
1985) and Harris (Harris, 1994), the limited data are available. In the last verage of the CTG should be achie-
aims of surgical coverage of perio- decades, coronally advanced flaps ved. Therefore, it has been sugges-
dontal recessions are the establish- (Zucchelli and DeSanctis, 2000), ted to coronally advance the pouch
ment of a complete r oot coverage connective tissue grafts using the and the tunnel. This modification has
with a minimum of keratinized (at “envelope” technique with prepara- been described by Azzi and Etien-
least 2 mm width), healthy perio- tion of a supraperiosteal mucosa flap ne (Azzi and Etienne, 1998). It re-
dontal tissue (pr obing depth < 3 (Raetzke, 1985) and its extension quires a mucoperiostal dissection
mm, no bleeding of probing) and an over more than one recession in form beyond the mucogingival junction
esthetical result and physiologic form of a tunnelling pr ocedure (Allen, and under each papilla. Another mo-
of the gingiva. The meaning of tis- 1994) were the base of modifica- dification is the application of a mi-
sue thickness for stabilization of tions and new flap designs to treat crosurgical approach using micr o-
treatment results, e.g. the goal to multiple recessions. In order to use surgical blades and sutures, which
turn a thin into a thick biotype, has an incision-free technique to cover minimizes the surgival trauma (Zuhr
already been emphasised in earlier recessions with optimal aesthetic et al., 2007; Cortellini andT onetti,
studies (Wennström, 1990). appearance, the tunnel technique 2001). New tunnel instruments (e.g.
Many surgical techniques have been has been further developed and mo- Tunneling Knife I/II, Hu-Friedy, Rot-
proposed to achieve root coverage. dified (Azzi and Etienne, 1998; Za- terdam) which ar e small, specially
Systematic reviews with meta-ana- balegui et al., 1999). In the present curved elevators have been deve-
lyses (Roccuzzo et al., 2002; Oates article, indications, options and li- loped in order to facilitate the supra-
et al., 2003; Cairo et al., 2008) de- mitations for this technique will be periosteal preparation of the tunnel
monstrated that for coverage of lo- reported. and minimize the risk for iatrogenic
calized Miller class I and II r eces- perforations. The main dif ferences

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regarding indication and flap desi- Both factors ar e important for the recent study (Thalmair et al., 2011),
gn between the envelope technique, establishment of stable periodontal the amount of r oot coverage after
the original tunnel technique and the and/or peri-implant tissue. treatment of eight patients with mul-
modified tunnel technique are pre- To date, there are only three studies tiple Miller class I recessions using
sented in table 1. Figure 1 shows published reporting results after root the modified tunnel technique was
an example of a modified tunnel coverage using the tunnel technique. examined. The authors r eport a
technique in a patient with multiple Aroca et al. treated 20 patients with mean coverage rate of 93.3% after
Miller class III recessions. multiple Miller class III r ecessions six months. If the initial r ecession
in a randomized contr olled split depth was < 4 mm, complete co-
mouth study (Ar oca et al., 2010). verage was found in 84%, in cases
Advantages They used a modified tunnel ap- with initial r ecession depths of ≥
and efficacy proach to insert a CTG with and wi- 4 mm, only 44% could be comple-
of the modified thout enamel matrix derivates (EMD). tely covered.
tunnel technique The authors demonstrate that the In summary, limited data point to a
modified tunnel technique with CTG high efficacy of the modified tunnel
Although CAF in combination with is a pr edictable method for Miller technique using CTG, in particular
CTG has been considered as stan- class III recessions. The additional for recessions with moderate depths
dard for coverage of recessions for application of EMD, however, did (< 4 mm). Further studies with a hi-
a long time, the tunnel technique has not enhance the clinical outcomes. gher statistical power should be per-
been further developed because it The percentage of r oot coverage formed to verify the efficacy of this
offers several advantages. Since ver- was 82% (CTG + EMD) and 83% technique.
tical releasing incisions can be avoi- (CTG), respectively. In another stu-
ded, it is possible to pr eserve the dy on five patients with multiple re-
continuity of gingival papillae and cessions of Miller class I and II (Mo- Treatment options
optimize the blood supply of the flap. daressi and Wang, 2009), acellular for the modified
Thereby, interproximal tissue sup- dermal matrix has been used ins- tunnel technique
port is pr ovided by the underlying tead of CTG for the tunnelling ap-
CTG. Further, gain of keratinized tis- proach. In average, 61% o r ot cove- Unfortunately, an indication scheme
sue and thickening of the gingiva rage and 0.15% increase of tissue for the modified tunnel technique
can be achieved with this technique. thickness could be ach ieved. In a has not been reported in the litera-

Original tunnel technique


Envelope technique Modified tunnel technique
modifiée

Single or multiple
Indication Singular recessions Multiple recessions
adjacent recessions
Horizontal extension
One tooth Multiple adjacent teeth Multiple adjacent teeth
of the mucosal flap
Mobilization
No No Yes
of the adjacent papillae
Coronal advancement
No No Yes
of the mucosal flap

The table shows the main differences between envelope technique (Raetzke et al., 1985), the original tunnel technique (Allen, 1994) and the modidied
tunnel technique (Azzi and Étienne, 1998) regarding to indication and flap design.

Table 1. Differences between envelope, original tunnel and modified tunnel techniques.
Tableau 1. Différences entre les techniques de l’enveloppe, de tunnélisation d’origine et de tunnélisation modifiée.

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1a 1b

1c 1d

1e 1f

Fig. 1. Modified tunnel technique for coverage of multiple Miller class III recessions. a. Pre-operative view. b. Intrasulcular incision and preparation of
a supraperiosteal mucosa flap. c. Coronal advancement of the tunnel flap. d. Insertion of the CTG. e. Fixation of the CTG using external vertical mat-
tress sutures. f. Healing result 3 months post-operative.
Fig. 1. La technique de tunnélisation modifiée pour le recouvrement de récessions multiples de classe III de Miller. a. Vue préopératoire. b. Incision intra-
sulculaire et préparation d’un lambeau muqueux supra-périosté. c. Déplacement en direction coronaire du lambeau tunnélisé. d. Insertion de la greffe
de tissu conjonctif. e. Fixation de la greffe de tissu conjonctif à l’aide de sutures au point de matelassier verticales externes. f. Résultat de la cicatrisa-
tion à 3 mois postopératoires.

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ture by now. However, there are dif- coronally advanced flaps (with CTG Coverage
ferent treatment options that can be or EMD) seem to be a better alter- of singular recessions
recommended. native (fig. 2). In patients with mul-
tiple Miller class II, the modified tun- Raetzke described the envelope
Coverage nel technique can be a very efficient technique in order to cover singu-
of multiple recessions method since tunnel preparation api- lar recessions using a CTG which
cally to the recession doesn’t requi- was sutured or sticked in a supra-
According to the original idea of the re mobilisation of attached gingiva periosteal “envelope”, prepared as
tunnel technique, this method can (fig. 3). In these cases the tunnel recession s urrounding m ucosal
be recommended for coverage of covering tissue mainly consists of flap without vertical r eleasing in-
multiple recessions with Miller class alveolar mucosa which makes mo- cisions (Raetzke, 1985). One of the
I, II or III if the recession depths are bilisation and coronal advancement disadvantages of this technique
moderate (< 4 mm). From a practi- of the tunnel easier (less tissue ten- was the fact that a high amount of
cal point of view, it should be noted sion). Also for Miller class III reces- the CTG was uncovered and pre-
that the difficulty of supracrestal pre- sions the tunnel technique provides dictability of root coverage was li-
paration beyond the mucogingival good results (Aroca et al., 2010). In mited due to the risk of (partial)
junction increases with the width of contrast to Miller class I, dissection necrosis of the (often) wide expo-
attached gingiva apically to the re- of the interdental papillae for coro- sed CTG. By undermining the ad-
cession. For multiple Miller class I nal advancement of the tunnel com- jacent papillae, the modified tun-
recessions with wide attached gin- plex even seems to be facilitated in nel technique enables cor onal
giva beyond the recession (≥ 3 mm), Miller class III (fig. 1). advancement of the tunnel.

2a 2b

2c 2d

Fig. 2. Example for an indication of a coronally advanced flap. a. Multiple Miller class I recessions with ≥ 3 mm width of keratinized tissue apical to the
recessions. b. Incision design (according to Zucchelli and De Sanctis, 2000). c. Post-operative view. d. Healing results 3 months post-operative.
Fig. 2. Exemple d’une indication de lambeau déplacé coronairement. a. Récessions multiples de classe I de Miller avec ≥ 3 mm de largeur de tissu kéra-
tinisé situé apicalement aux récessions. b. Tracé d’incision (d’après Zucchelli et De Sanctis, 2000). c. Vue postopératoire. d. Résultats de la cicatrisation
à 3 mois postopératoires.

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Therefore, a higher amount of the Gingival thickening a preceding thickening of the gingi-
CTG can be covered (fig. 4). (“biotype switching”) va in order to avoid gingival tissue
Similar to the multiple r ecessions, loss after crown insertion (Borghet-
the modified tunnel technique is not Orthodontic movement of teeth ti et al., 1990).
a suitable method if the amount of might lead to iatrogenic exposure of
attached gingiva apically to the re- roots, in particular in patients with Peri-implant soft tissue
cession is ≥ 3 mm (alternative: CAF thin gingival biotypes (W ennström, augmentation
+ EMD/CTG) or if the depth of the 1996). In those patients gingival aug-
recession is ≥ 4 mm (alternative: la- mentation (“biotype switching”) prior Treatment on gingival r ecessions
teral sliding flap +EMD/CTG (fig. 5) to the orthodontic treatment can pre- (dehiscence defects) on implants is
or free gingival graft). vent development of r ecessions still a challenge in mucogingival sur-
Figure 6 shows a decision guideli- (fig. 7). Also restoration of teeth with gery. In order to remain or augment
ne for the indication of the modified crowns with subgingival margin in peri-implant tissue, we cr eated a
tunnel technique in or der to cover esthetically relevant regions and thin treatment strategy for tissue condi-
gingival recessions. gingival biotype might benefit from tioning prior, during or after implant

3a 3b

Fig. 3. Coverage of two adjacent Miller class II recessions using the modi-
fied tunnel technique. a. Pre-operative view. b. Post-operative view. c. Hea-
ling result 4 months post-operative.
Fig. 3. Recouvrement de 2 récessions adjacentes de classe II de Miller avec
la technique de tunnélisation modifiée. a. Vue préopératoire. b. Vue post-
3c opératoire. c. Résultat de la cicatrisation à 4 mois postopératoires.

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4a

4b

Fig. 4. Coverage of a singular Miller class II recession using the modified


tunnel technique. a. Preoperative view. b. Post-operative view. c. Seven
days post-operative (after suture removal).
Fig. 4. Recouvrement d’une récession unitaire de classe II de Miller avec
la technique de tunnélisation modifiée. a. Vue préopératoire. b. Vue post-
4c opératoire. c. Sept jours postopératoires (après la dépose des sutures).

insertion using the modified tunnel overlapping flap only. Therefore, root the papillae adjacent to the implant
technique. coverage with CTG will lead to a (fig. 9).
In patients wher e teeth with gingi- more stable gingival augmentation
val recessions or thin gingival bio- than on implants and should be
types are planned to be replaced by considered whenever a tooth with a Limitations
immediate implants, we aim to co- gingival deficit should be r eplaced and conclusion
ver the recessions and/or increase by an (immediate) implant (fig. 8).
the gingiva thickness on the tooth Also during the insertion of an im- The modified tunnel technique is an
three months prior to extraction and plant a CTG might help to impr ove incision-free, minimally invasive me-
implant insertion. Since blood sup- the quantity and quality of peri-im- thod for gingival augmentation as
ply for the CTG on the tooth is pro- plant tissue. Alternatively or additio- blood supply can be maximally pre-
vided by blood vessels from perio- nally, gingival augmentation can be served and coverage of the graft is
dontal plexus, supraperiosteal plexus performed after implant insertion, in optimised compared to former tech-
and the covering flap (Guiha et al., particular during implant exposure. niques. However, there are limita-
2001), on implants nutrition for a Thereby, the modified tunnel tech- tions and contraindications which
CTG is given by a comparably com- nique represents an elegant method should be considered.
promised periostal nutrition and the to insert the CTG by careful lifting of

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5a

5b

Fig. 5. Example for an indication of a lateral sliding flap. a. Pre-operative


view. Recession depth ≥4 mm. Absence of keratinized tissue apical to the
recession. b. Incision design. c. Healing result after 3 months.
Fig. 5. Exemple d’indication de lambeau de translation latérale. a. Vue
préopératoire ; profondeur de la récession ≥4 mm ; absence de tissu kéra-
tinisé dans la zone apicale à la récession. b. Tracé d’incision. c. Résultat de
la cicatrisation à 3 mois.

Fig. 6. Indication scheme for the treatment of recessions of Miller class I,


II and III dependent on the presence of keratinized tissue apically and late-
rally to the recession defect, recession depth and gingival biotype. The
modified tunnel technique can be recommended in cases with limited
attached gingiva apically (< 3 mm) and recession depths of not more than
4 mm in Miller class I, II and III. Alternatively and in cases with recession
5c depths of ≥4 mm, lateral sliding flaps can be considered if sufficient late-
ral keratinized tissue is present. In patients with lack of apical and lateral
keratinized tissue, free gingival grafts may be
applicable.
Recessions KT: keratinized tissue; CAF: coronally advanced
Miller’s class I, II, III flap; EMD: enamel matrix derivates; CTG:
connective tissue graft.
Fig. 6. Protocole d’indication pour le traitement
Miller’s class I Miller’s class I, II, III de récessions de classes I, II et III de Miller selon
la présence de tissu kératinisé dans la zone api-
KT apical ≥ 3 mm KT apical < 3 mm cale et latérale de la récession, la profondeur de
la récession et le biotype gingival. La technique
THICK biotype THIN biotype Recession depth de tunnélisation modifiée peut être recomman-
Recession depth dée pour les cas de gencive attachée limitée dans
< 4 mm ≥ 4 mm la zone apicale (< 3 mm) et des profondeurs de
récession n’excédant pas 4 mm dans des classes
I, II et III de Miller.
CAF + EMD CAF + CTG YES En solution de remplacement, et pour les cas de
KT lateral récession dont la profondeur est ≥ 4 mm, les
lambeaux de translation latérale peuvent être
NO envisagés si l’on dispose d’une quantité de tissu
Lateral sliding flap kératinisé suffisante. Chez les patients présen-
tant un manque de tissu kératinisé dans les zones
(+ EMD/CTG) Free gingival apicales et latérales, on peut réaliser des greffes
Modified tunnel Double papilla flap graft gingivales libres.
technique (+ EMD/CTG) TK : tissu kératinisé ; LDC : lambeau déplacé
6 coronairement ; DMA : dérivés de la matrice
amélaire ; GTC : greffe de tissu conjonctif.

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7a 7b

7c 7d

Fig. 7. Gingival thickening prior to orthodontic treatment. a. Pre-operative view with thin gingival biotype and initial recession (Miller class II) on the
right lower central incisor. b. Tunnelling preparation using two vertical « slot incisions » within the alveolar mucosa in order to insert the CTG. c. Post-
operative view with sutures. d. Healing result 3 months post-operative.
Fig. 7. Épaississement gingival préalable à un traitement orthodontique. a. Vue préopératoire en présence d’un biotype gingival fin et d’une récession
initiale (classe II de Miller) sur l’incisive centrale mandibulaire droite. b. Préparation à l’aide de 2 incisions verticales « en fente » réalisées dans la
muqueuse alvéolaire pour y glisser la greffe de tissu conjonctif. c. Vue postopératoire avec les sutures. d. Résultats de la cicatrisation à 3 mois postopé-
ratoires.

Besides general contraindications tors such increased flap tension (Pini- papillae, is essential for avoiding per-
for oral sur gical treatments, smo- Prato et al., 2000) and surgical trau- forations. In a few cases, dissection
kers have a higher risk for impaired ma (Burkhardt et al., 2005) will limit of extremely thin papillae may be
wound healing, graft necrosis and the gain of root coverage. Finally, it not possible due to the high risk of
infection, which will worsen the re- must be emphasized that especial- ruptures.
sults of root coverage with CTG (Mar- ly the modified tunnel technique is As presented in figure 6, in patients
tins et al., 2004; Chambrone et al., a very technique sensitive method with high recession depths (> 4 mm)
2009). Further, initial thickness of the that requires experience and skills and absence of keratinized tissue
flap correlates with tr eatment suc- of the surgeon. Careful preparation apically and laterally to the r eces-
cess (Baldi et al., 1999; Hwang and of the flap, in particular in patients sion, a staged approach with a free
Wang, 2009). Also, tr eatment fac- with thin biotype and small gingival gingival graft shoul d be pr eferred

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8a 8b

8c 8d

8e 8f

Fig. 8. Modified tunnel technique prior to extraction and implant insertion. a. Upper central incisors with 2 mm recessions (covered by crowns). The
right incisor is planned to be extracted. b. Replacement of both crowns by provisionals with shortened crown length. c. Coverage of both recessions
using the modified tunnel technique with two « slot incisions ». d. Healing result 2 months later. e. Healing abutment 6 months after immediate implant
insertion on the right central incisive. F. Definitive crowns on both central incisors.
Fig. 8. Technique de tunnélisation modifiée avant extraction et implantation. a. Incisives centrales maxillaires présentant des récessions de 2 mm (cou-
ronnées). L’extraction de l’incisive droite est programmée. b. Remplacement des 2 couronnes par des provisoires plus courtes. c. Recouvrement des
2 récessions à l’aide de la technique de tunnélisation avec deux incisions « en fente ». d. Résultat de la cicatrisation 2 mois plus tard. e. Pilier de cicatri-
sation 6 mois après la pose d’un implant immédiat remplaçant l’incisive centrale droite. f. Couronnes finales sur les 2 incisives centrales.

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against tunnelling techniques. This – experience of the surgeon; particular multiple recessions, with
might, in particular, be the case if – size of the recession defects; improved integration of the graft due
multiple recessions in the lower jaw – amount of surr ounding keratini- to avoidance of vertical releasing in-
are associated with a very flat ves- zed tissue. cisions and maximal preservation of
tibulum. Regarding these parameters, the blood supply.
In summary, (differential) indication modified tunnel technique is an in-
for the tunnel technique should be novative method which extends the
done considering: spectrum of plastic periodontal sur-
– general health and smoking ha- gery. It allows gingival augmenta-
bits of the patient; tion in different clinical situations, in

9a 9b

9c 9d

Fig. 9. Modified tunnel technique during implant exposure in order to remain and optimize peri-implant soft tissue. a. Upper left lateral incisor prior
to extraction due to periodontal bone loss. b. Six months after implant insertion and gingival forming by an ovate pontic. c. Mobilisation of the adja-
cent papillae. d. Preparation and coronal advancement of the tunnel.
Fig. 9. Technique de tunnélisation modifiée lors de l’exposition de l’implant afin de pérenniser et d’optimiser les tissus mous péri-implantaires. a. Inci-
sive latérale maxillaire gauche avant extraction, à la suite d’une perte osseuse d’origine parodontale. b. Six mois après la pose de l’implant, remode-
lage gingival à l’aide d’un pontique ovoïde. c. Mobilisation des papilles adjacentes. d. Préparation et déplacement en direction coronaire du tunnel.

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The modified tunnel technique – options and indications for mucogingival therapy
Technique de tunnélisation modifiée : options et indications en chirurgie muco-gingivale

9e 9f

Fig. 9. Modified tunnel technique during implant exposure in order to remain and optimize peri-implant soft tissue. e. Insertion of the CTG. f. Healing
result and definitive crown.
Fig. 9. Technique de tunnélisation modifiée lors de l’exposition de l’implant afin de pérenniser et d’optimiser les tissus mous péri-implantaires. e. Inser-
tion de la greffe de tissu conjonctif. f. Résultat de la cicatrisation et couronne finale.

Journal de Parodontologie & d’Implantologie Orale - Vol. 31 N°1


> OS X Couleur
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J. M. STEIN, C. HAMMÄCHER

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S e n d re p r i n t s re q u e s t s t o
Priv.-Doz. Dr. Jamal M. Stein, MSc.: Praxiszentrum für Implantologie, Parodontologie und Prothetik – Schumacherstrasse 14 –
52062 AACHEN – GERMANY – J.M.Stein@gmx.de

Journal de Parodontologie & d’Implantologie Orale - Vol. 31 N°1

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