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Received: 16 August 2019    Revised: 3 October 2019    Accepted: 14 October 2019

DOI: 10.1111/and.13473

ORIGINAL ARTICLE

The efficacy of regular penis‐root masturbation, versus Kegel


exercise in the treatment of primary premature ejaculation: A
quasi‐randomised controlled trial

Mingyang Jiang1 | Guanqiang Yan2 | Huachu Deng2 | Hao Liang2 | Yunni Lin2 |


Xun Zhang1

1
Department of Andrology, The First
Affiliated Hospital of Guangxi Medical Abstract
University, Nanning, China To explore the efficacy of regular penis‐root masturbation (PRM) versus Kegel exer‐
2
Guangxi Medical University, Nanning, China
cise (KE) in the treatment of primary premature ejaculation (PPE). This study was a
Correspondence prospective quasi‐randomised controlled trial. Thirty‐seven heterosexual males with
Xun Zhang, Department of Andrology, The
PPE were selected according to the time sequence of outpatient consultations and
First Affiliated Hospital of Guangxi Medical
University, Nanning, Guangxi, China. the preliminary results of a pre‐experiment and were assigned to an PRM group and a
Email: drrzhangxun@126.com
KE group. Differences in intravaginal ejaculatory latency times (IELTs) and premature
ejaculation diagnostic tool (PEDT) scores were compared between the two groups.
The study was approved by the Ethics Committee of the First Affiliated Hospital of
Guangxi Medical University. Among the 37 PPE patients, 18 performed PRM and 19
patients performed KE. The IELTs of patients who performed PRM and KE were sig‐
nificantly prolonged before treatment, and the difference after treatment was statis‐
tically significant (p < .05). Compared with the KE group, the IELT prolongation effect
in the PRM group was more significant PRM (p < .05). The PEDT scores of patients
after performing PRM and KE were significantly lower than those before performing
these exercises (p < .05). Compared with the KE group, the PEDT scores of the PRM
group exhibited a greater decrease (p < .05). Thus, both PRM and KE have therapeutic
effects on PPE. Compared with KE, PRM is more effective in the treatment of PPE.

KEYWORDS
Kegel exercise, primary premature ejaculation, RCT, regular penis‐root masturbation

1 |  I NTRO D U C TI O N premature ejaculation. Compared with healthy males, PE patients


have less sexual function and satisfaction as well as more psycho‐
Premature ejaculation (PE) is the most common sexual dys‐ logical disorders and interpersonal relationship difficulties, and
function in males. In 2014, the International Society of Medical their partners' satisfaction with sexual relationships decreases as
Sciences (ISSM) updated the definition of PE (Althof et al., 2014). the condition worsens. Treatment for PE may involve a range of
The prevalence of PE is estimated to be 20%–30% accord‐ interventions, including systemic medications (such as selective
ing to the definition of the American Diagnostic and Statistical serotonin reuptake inhibitors [SSRI], tricyclic antidepressants,
Manual of Mental Disorders (DSM‐IV; Laumann, Paik, & Rosen, phosphodiesterase type 5 inhibitors and analgesics; Smits et al.,
1998) and the updated version of the International Society of 2007), local anaesthetics or sprays, and behavioural therapies
Sexual Medicine's Guidelines for the diagnosis and treatment of (BTs; Swenson et al., 2015). Among them, selective serotonin

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https://doi.org/10.1111/and.13473
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reuptake inhibitors are commonly used drugs. Lifelong PE may be a pre‐experiment (i.e., patients for whom ejaculation occurred too
due to dysfunction of the serotonin pathway of the central sys‐ quickly after the beginning of sexual intercourse, ejaculation within
tem, and SSRI and serotonin agonists can increase the intravaginal the vagina occurred in <1 min, ejaculation could not be controlled
ejaculation latency time (IELT), resulting in a significant benefit and ejaculation could not be controlled with any sexual partner
of SSRIs for PE treatment. However, due to the side effects of under any condition).
these drugs, patient compliance is low (Kilinc, Aydogmus, Yildiz, &
Doluoglu, 2018; Yildiz, Kilinc, & Doluoglu, 2018).
2.2 | Inclusion criteria
Behaviour therapy and psychotherapy for PE include two
major types of overlapping treatments (Althof et al., 2014). The (a) Men with PPE, including those with rapid initial ejaculation, lack
first category includes sexual counselling aimed at addressing of control of ejaculation and vaginal ejaculation within <1 min; (b)
the psychological and interpersonal conflicts that cause PE. The Men in a stable heterosexual relationship with sexual partners who
second category includes behavioural therapy, which helps men supported the research methods involved in the study; (c) Men with
develop sexual skills, delay ejaculation and increase sexual self‐ a duration of PPE longer than 1 year; (d) Men with good compliance
confidence. Common behavioural treatments include the follow‐ who could receive weekly WeChat follow‐up guidance and undergo
ing methods. (a) The “stop‐start” technique, introduced by Simon, monthly clinical visits.
which involves a man or his partner stimulating the penis until
he feels the urge to ejaculate and then stopping until the feeling
2.3 | Exclusion criteria
disappears. This requires several repetitions to allow ejaculation
(Hidetoshi, 2011). The goal is to learn to recognise the sensation (a) Secondary premature ejaculation (SPE), including acquired PE,
of impending ejaculation to improve the control of ejaculation. men previously able to achieve sufficient ejaculation time control,
(b) According to the related “squeeze” technique proposed by those with vaginal ejaculation occurring in <3 min, men who re‐
Masters and Johnson, the man's partner stimulates the penis until ported distressed, troubled, or frustrated feelings and/or those
he feels the urge to ejaculate and then squeezes the glans of the who avoided sexual intimacy; (b) Homosexual patients or those
penis until the feeling disappears. After several repetitions, he can with behaviours such as exhibitionism, voyeurism, fetishism and
ejaculate. The man and his partner first focus on an area outside cross dressing. Such patients typically lack excitement for het‐
of the genitals, excluding the breasts, and sexual intercourse, to erosexual vaginal intercourse, often because of forced fertility
encourage physical sensation and reduce performance anxiety. treatment after complaining of PE, and require further psycho‐
Then, genital contact is gradually introduced, and finally, complete logical behavioural counselling or treatment; (c) Patients with a
sexual intercourse occurs (Mcmahon et al., 2010). (c) Pelvic floor poor relationship with their sexual partner, which could affect
muscle rehabilitation training also helps to control ejaculation the performance and implementation of treatment; (d) PPE com‐
(Pastore et al., 2012). bined with erectile dysfunction; (e) PPE combined with obvious
The purpose of this study was to select primary premature ejacu‐ organ disease that may be related to the condition, such as PPE
lation (PPE) patients from a clinic to undergo guided penis‐root mas‐ combined with hypogonadism; and (f) Patients with severe schizo‐
turbation (PRM; Ma, Zou, Lai, Zhang, & Zhang, 2019) and observe the phrenia, anxiety, depression or other neurological symptoms or
improvement of vaginal ejaculation latency after 3 months of practice poor compliance.
as well as to compare the efficacy of PRM and Kegel exercise (KE). The
study aimed to provide a new method of treatment for PE.
2.4 | Collection of clinical data
We collected the patient's name, age, duration of the disease and
2 |  M E TH O DS record the intravaginal ejaculation latency time (IELT) and the pre‐
mature ejaculation diagnostic tool (PEDT) score before and after
This trial was carried out according to CONSORT‐revised 2010 treatment.
guidelines. The trial programme protocol was approved by the
Ethics Committee of the First Affiliated Hospital of Guangxi Medical
2.5 | Diagnostic criteria
University (KY‐E‐069) and registered with the Chinese Clinical Trial
Registry (ChiCTR1900024896). We began recruiting patients in
2.5.1 | Diagnostic criteria of the IELT
August 2019. The authors confirm that all related interventions were
registered. Waldinger and other scholars introduced the concept of intra‐
vaginal ejaculatory latency (IELT) in 1994, which is the time from
the insertion of the penis into the vagina until the male begins to
2.1 | Research object
ejaculate. The diagnosis of PE can be relatively objectively quanti‐
Primary premature ejaculation patients were enrolled accord‐ fied by measuring the IELT, which is the basis for clinical research
ing to the order of outpatient visits and the preliminary results of in PE.
JIANG et al. |
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F I G U R E 1   Flow chart

and the preliminary results of a pre‐experiment. A total of 48 pa‐


2.5.2 | Diagnostic criteria of the PEDT
tients were contacted, and four were excluded. Among the 44 PPE
The PEDT score measures the following five items: (a) difficulty in patients, 22 patients were assigned to the PRM group, and 22 pa‐
delaying ejaculation; (b) ejaculation before the patient intends; (c) tients were assigned to the KE group. After 3 months of follow‐up,
ejaculation with little stimulation; (d) frustration associated with PE; 37 patients completed the trial; of those, 18 practiced PRM and 19
and (e) couples' opinions about ejaculation. The retest reliability of practiced KE as shown in Figure 1. The baseline characteristics are
the PEDT was, and all items were significantly different between PE shown in Table 1. Before treatment, patients who were diagnosed
patients and non‐PE patients based on a diagnostic cutoff score. with PPE according to their medical history and related examinations
were given education and guidance on PRM skills and medication
methods. WeChat communication was established with patients,
2.6 | Statistical analysis
and follow‐up was performed once per week. Patients who were in‐
Statistical analysis was performed with the statistical software cluded in the trial were asked to visit the clinic once per month until
IBM SPSS STATISTICS 25.0. First, the data were tested for normal‐ the end of treatment.
ity and homogeneity of variance. In this trial, the sample size was
limited, the data were not normally distributed and the variance
3.2 | Comparison of the IELT before and
was not uniform. Therefore, we used the Wilcoxon signed‐rank
after treatment
test to calculate the differences in IELT and PEDT scores before
and after treatment. The Mann–Whitney U test was used to com‐ The median IELT of subjects before performing KE was 1 min, and
pare the differences in the IELT and PEDT scores before and after the median IELT of these subjects after performing KE was 2 min.
treatment between the two groups. The Wilcoxon signed‐rank test results showed that the IELT of pa‐
tients after treatment was significantly longer than that before KE
treatment (Z = −3.384, p = .001).
3 | R E S U LT S
The median IELT of subjects before performing PRM was 1 min,
and the median IELT of the subjects after treatment was 5 min. The
3.1 | Overall results
Wilcoxon signed‐rank test results showed that the IELT of patients
This study was a prospective quasi‐randomised clinical trial that in‐ after treatment was significantly longer than that before performing
cluded PPE patients based on the time sequence of outpatient visits PRM (Z = −3.744, p < .001).
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TA B L E 1   Baseline demographic data (mean ± SD) of primary TA B L E 3   Premature ejaculation diagnostic tool (PEDT) during
premature ejaculation patients at all stages of a quasi‐randomised the study
trial
  PRM KE Z p‐Value
  PRM KE p‐Value
PEDT
Number of patients 18 19   Pre‐treatment 16 (2) 17 (2) −0.872 .383
Age (year) 31.39 ± 8.39 29.58 ± 5.75 .164 Post‐treatment 10 (2) 15 (4) −4.395 <.001
Course of disease 11.5 ± 7.23 10.16 ± 5.68 .308 Z −3.744 −3.539    
(month)
p‐Value <.001 <.001    
Course of treat‐ 2.89 ± 0.32 2.68 ± 0.75 .017
ment (month) Difference value −6 (2) −2 (3) −4.472 <.001

Abbreviation: KE, Kegel exercise; PRM, penis‐root masturbation. Abbreviation: KE, Kegel exercise; PRM, penis‐root masturbation.

neuropathological disorders, genes and genetics. We found that a


The Mann–Whitney U test results showed that the IELT prolon‐ portion of patients complaining of nonejaculation in clinical visits
gation effect was more significant in the PRM group than in the KE had a history of masturbation in a prone position. By changing the
group. The difference in IELT between PRM group and KE group was method of masturbation, nonejaculation can be partially reversed.
statistical significance (Z = −4.388, p < .001) as shown in Table 2. Further observations revealed that the prone position masturbation
method can significantly prolong the IELT. Based on this method, we
have developed a new PRM method (Ma et al., 2019).
3.3 | Comparison of PEDT scores before and
The dorsal nerve of the penis root is a sensory nerve that is es‐
after treatment
sential for normal erection and ejaculation (Šedý, Naňka, Špačková,
The median PEDT score of subjects before performing KE was 17, & Jarolím, 2010). Frequent stimulation of the dorsal nerve branches
and the median PEDT score of these subjects after KE treatment was of the penis root can reduce penile sensitivity and central excitabil‐
15. The Wilcoxon signed‐rank test results showed that the PEDT ity to a certain extent, which may help to improve the ejaculation
score of patients after performing KE was significantly lower than threshold and prolong the IETL, thereby effectively treating PE
that before treatment (Z = −3.539, p < .001). (Althof et al., 2010).
The median PEDT score of subjects before performing PRM was The steps for PRM are as follows. One or both thumbs are placed
16, and the median PEDT score of the subjects after PRM treat‐ on the back of the penis root (within one to three of the penis), and
ment was 10. The Wilcoxon signed‐rank test results showed that the penis root is massaged in a circular motion or along the proximal
the PEDT score of patients after performing PRM was significantly end so that the patient experiences sexual pleasure and maintains
lower than that before treatment (Z = −3.744, p < .001). an erection. When the patient feels that they are about to ejaculate,
The results of Mann–Whitney U test showed that the PEDT score stimulation should be stopped immediately. When the feeling sub‐
of the PRM group was significantly lower than that of KE group. The sides, stimulation is continued. During the training, the partner is
difference in PEDT score between PRM group and KE group was allowed to touch and kiss the patient and provide audiovisual stimu‐
statistically significant (Z = −4.472, p < .001), as shown in Table 3. lation. PRM requires 10–15 min. Ejaculation and vaginal intercourse
are allowed after training. The training is conducted three times a
week for a period of 3 months and can be completed by the patient
4 |  D I S CU S S I O N or his partner.
The steps of traditional KE are as follows: (a) at 1 hr after eating,
Recent studies have shown that sexual problems in male patients the patient first empties their bladder and then rests in a supine posi‐
are associated with physical diseases such as metabolic syndrome, tion with a comfortable soft cushion for the head while relaxing their
whole body and mentally concentrating. (b) The feet of the patient
TA B L E 2   Intravaginal ejaculatory latency times (IELT) during the are separated by a shoulder width with the legs bent, and breath‐
study ing remains deep and slow. During inhalation, the muscles should
  PRM KE Z p‐Value be contracted in the anus, and then, the urethra is contracted, sim‐
ilar to the movement of urine. The muscles of the pelvic floor are
IELT
then lifted. Contraction is continued for 3–5 s, and then, the patient
Pre‐treatment 1 (1) 1 (1) −0.233 .816
slowly relaxes as they exhale. As many pelvic floor muscles as possi‐
Post‐treatment 5 (2) 2 (2) −3.559 <.001
ble should be exercised to avoid contraction of the thighs, buttocks
Z −3.744 −3.384    
and muscles. Contraction and relaxation of the pelvic floor muscles
p‐Value <.001 .001     are alternated rhythmically. This should be practiced three times a
Difference value 3 (2) 1 (2) −4.388 <.001 day with 50–100 repetitions each time. Urination should be per‐
Abbreviation: KE, Kegel exercise; PRM, penis‐root masturbation. formed after practice.
JIANG et al. |
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A recent study evaluated 10 randomised controlled trials (RCTs) will have great influences. The patient's marital relationship and
of behaviourally treated PE patients. Four studies suggested that their partner's cooperation are also factors that are beyond the
behavioural therapy can prolong the IELT compared with a control control of the study; (f) We could not follow‐up the two groups
group. Two studies suggested that behavioural therapy was not ef‐ after 3 months; therefore, we cannot determine whether there
fective. Four other studies suggested that traditional behavioural is a need for continuous training to maintain progress. This issue
therapy combined with drug therapy was less effective but could is important because it is necessary to assess whether follow‐up
significantly improve the IELT (0.5 min). This evidence revealed that medication or psychosocial intervention are needed; (g) Smoking,
behavioural therapy could extend the ejaculation latency and that drinking and organic diseases all affect the ejaculation latency of
combination therapy achieved better results than therapy without patients. However, considering that PE patients are generally out‐
drug treatment. However, more RCTs are needed to evaluate the patients who do not undergo hospitalisation and follow‐up is dif‐
psychological treatment of PE (Abu & Abdelhamed, 2017; Cooper ficult, we cannot comprehensively complete the medical records;
et al., 2015; Park, Park, & Moon, 2015). Studies have shown that (h) According to Waldinger, Zwinderman, Olivier, and Schweitzer
approximately 30% of PE patients treated with paroxetine choose to (2008), the geometric mean should be used for all studies because
discontinue the treatment after a relatively short time, and approx‐ some measurements may be more strongly influenced by outliers.
imately 20% of people refuse to start medical treatment (Salonia et However, since our sample size was relatively small and was not a
al., 2009). Furthermore, 90% of PE patients choose to discontinue skewed distribution, we used the arithmetic mean.
treatment within 1 year (Mondaini et al., 2013). Drug treatment In summary, the above results need to be further confirmed by
compliance is not high. Reasons for discontinuation of medication large‐scale, multi‐centre, controlled trials including patients with
include the cost of the drug, unsatisfactory efficacy and the need different age groups, education and income levels and regions of
to take the drug before sexual intercourse. Psychosocial treatment residence.
interventions were once the first‐line treatment option for PE, and
the stop–start technique that Semans (1956) first described and sub‐
sequently used multiple variants of is arguably the most common 5 | CO N C LU S I O N S
treatment. However, a meta‐analysis of psychosocial treatment in‐
tervention studies of PE showed that the results were not sustained. Both PRM and KE have therapeutic effects on PPE. Compared with
In particular, for long‐term treatment, the meta‐analysis indicated KE, PRM is more effective in the treatment of PPE.
that the initial treatment was successful, but relapse occurred at
3 years after treatment (Corona et al., 2017; Glina et al., 2010).
AC K N OW L E D G E M E N T S
The potential clinical significance of this study is as follows. (a)
Our study systematically proposed PRM for the first time, and the This work was supported by the First Affiliated Hospital of Guangxi
steps of this new behavioural treatment are easy to implement. (b) Medical University.
This is the first study to compare the efficacy of PRM and KE in
the treatment of PPE. (c) In the course of the study, no side effects
were observed in the two groups. Compared with drug therapy with C O N FL I C T O F I N T E R E S T
psychosocial intervention therapy, this method has an advantage
All authors declared no competing interests.
because drug side effects are one of the main reasons that patients
stop treatment.
The study had the following limitations. (a) The number of sub‐ AU T H O R C O N T R I B U T I O N S
jects was small, and some patients were lost to follow‐up or with‐
X.Z. designed the clinical trial. M.J. and G.Y. collected data and per‐
drew during the follow‐up; (b) Some patients were followed up for
formed data analysis. M.J., G.Y., H.L. and Y.L. wrote the manuscript.
<3 months, which may lead to bias in the results; (c) Differences
All authors read and approved the final manuscript.
in geography, customs, social life, background, economic develop‐
ment and educational level may lead to differences in follow‐up
results, which may lead to potential bias in the results; (d) Since ORCID
the patient is not hospitalised, there is no method of monitoring
Xun Zhang  https://orcid.org/0000-0002-1001-7522
whether the patient is regularly performing PRM or KE, using
other drugs or undergoing psychosocial intervention, which may
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