Drug Classificat Mechanism of Action Indication Contraindic Adverse Nursing Responsibilities

Data ion ation Effect/Reactio

n
Generic Therapeut
Pharmacodynamics: General Contraindic Before:
Name: ic: The plasma kinetics of Indication: ated in: Hypercalcemia 1.Assess electrolyte levels
Ketoanalo Supplemen
amino acids and their Prevention and Hypercalcemi may develop. 2.Explain therapeutic value of drug
gue ts integration in metabolic therapy of a, disturbed 3.Assess allergy to the drug
pathways are well damages due amino acid 4.Caution patient of the different side
Trade Pharmaco established. It should to faulty or metabolism.  effects
Name: logic: nevertheless be noted deficient In case of 5. Assess vital signs
Ketosteril that, in uremic patients, protein hereditary 6. Proper preparation of the drug
e - the plasma disturbances metabolism in phenylketonu
do not seem to depend chronic renal ria, it has to During:
Patient’s Pregnancy on digested amino acid insufficiency i be taken into 1. Verify patient’s identity
Dose: Category intake, and that the post- n connection account that 2. Administer with food to prevent GI
1 tab PO Risk: absorptive kinetics with limited ketoanalogue upset
TID seems to be distributed protein food of contains 3. Administer drug at right time, route,
Not very early in the ≤40 g/day (for phenylalanine and dosage
Minimum established development of the adults). . Disturbed 4. Advise to swallow the tablet whole
Dose: disease. amino acid 5. Monitor vital signs
1 tab In normal individuals, metabolism
thrice a there is an increase in Patient’s After:
day the plasma level of Actual Precaution: 1. Document administration of drug
ketoanalogues, 10 min Indication: Ketolog 2. Instruct patient to report
Maximu after oral ingestion. Supplements should be immediately if symptoms of
m Dose: These levels reach indicated for taken during hypercalcemia occurs like muscle
8 tabs values that are patients having meals to weakness, constipation
thrice a approximately 5 times urologic allow proper 3. Monitor calcium levels.
day higher than the initial problems like absorption 4. Monitor for signs of hypercalcemia
level. Peak levels are chronic kidney and and electrolyte levels.
reached within 20-60 disease. metabolism 5. Monitor vital signs especially
Contents: min and normal levels into the cardiac changes.
Ketoanalo are reached again after correspondin
gues and 90 min. Gastrointestinal g amino
essential absorption is thus very acids. The
amino rapid. In the plasma a serum
acids simultaneous increase in calcium
levels of the levels should
Availabili ketoanalogue and the be monitored
ty: corresponding amino regularly.
tablets acid show that Ensure the
transamination of the sufficient
Route/s ketoanalogues are very supply with
for rapid. Due to natural calories.
Administ pathways of disposal of Use in
ration α-ketonic acids in the pregnancy: 
PO organism, it is probable No
that exogenous intakes experience
are very rapidly has been
integrated into metabolic made so far
cycles. Ketoacids follow with the
the same catabolic application in
pathways as the classical pregnancy.
amino acids. No specific Use in
study on ketoacid children: No
excretion has been experience
performed to date. has been
made so far
Pharmacokinetics:  with the
Absorption: application in
Absorption in the pediatry.
gastrointestinal tract.
Interaction:
Distribution: Widely Drug-Drug:
distributed Simultaneous
administratio
Metabolism & n of
Excretion: Metabolized medicaments
by the liver, excreted by containing
the liver. calcium (eg,
acetolyte)
Time Reaction Profile may lead to
pathological
Rou On Pe Dur increases of
te set ak atio the serum
n calcium level
PO 10 20 unkn or
mi - own intensificatio
n 60 n. As the
mi uremic
n symptoms
improve
under
Half-Life: Ketolog, a
Unknown possible
administratio
n of
aluminum
hydroxide
should be
reduced. Pay
attention to a
reduction of
serum
phosphate.
Do not take
drugs
together with
Ketolog that
form
sparingly
soluble
compounds
with calcium
(eg,
tetracyclines)
in order not
to interfere
with
absorption.