Professional Documents
Culture Documents
EVOLUTION OF PHARMACY
a) WHAT IS PHARMACY?
i. Derived from the Greek word PHARMAKON means “Medicine” or
“Drug”
ii. It is the art and science of preparing, dispensing, and proper utilization of
medications and the provision of drug-related information to the public.
iii. It is where we study how to prepare, how to dispense, and how to
properly utilize medications or drugs.
iv. In different aspect, it is also known as DRUGSTORE – it is a place
where drugs are sold.
2. HISTORY OF PHARMACY
Recent drugs in healing, was actually as old as civilization itself
It existed long before the word pharmacy / drug existed
a) SUPERSTITIOUS BELIEF
i. Before, the theories are often involved magic and superstitious beliefs
but development in medical, astronomical, and cosmological ideas.
ii. The first culture to consider this ideas, scientifically was actually the
Greeks, wherein they made a logical speculation rather than just
relying on myths or mythology.
b) TERRA SIGILLATA
i. The modern archeologist, they have an ----, CLAY TABLETS which
contains 300 medicinal preparation, we called it the Terra Sigillata
found in Mediterranean Island of Lemnos.
ii. It is consider as an early trademark drug
d) PAPYRUS EBERS
i. It is Ebers Papyrus book.
ii. It is the best known and important pharmaceutical record, because it is a
collection of 800 prescriptions, mentioning 700 drugs.
e) DE MATERIA MEDICA
i. Pedanius Dioscorides
1. a Greek physician.
2. He is credited with writing one of the world’s greatest
pharmaceutical text, which we called it De Materia Medica or in
English “ on medical matters”
ii. It served as the standard reference text for drugs
iii. It is considered as the four runner of modern day reference such as the
United States of pharmacopeia (USP) and the Physicians
iv. Thus, the modern day formularies are actually based on this drug list
f) GALEN
i. He is a Greek professor of Pharmacy and Medicine
ii. He studied the effect of herbal medicine on the human body leading to
the term Galenical Pharmacy or the process of creating extracts of
active medicinal from plants which we used as one of the component,
factor that we consider as a source in research for the discovery of drugs.
b) ARABIC CIVILIZATIONS
i. were some of the first cultures to develop a list of drugs and dosage
forms (pills, syrups, extracts), and to identify the pharmacist as a
qualified healthcare professional
ii. It starts in 18th century
c) APOTHECARY (Pharmacy)
i. modeled after ancient Greek and Arabic cultures
ii. The first Apothecary shop was first establish Baghdad by the Arabs
1. Arabs are the first culture who recognized Pharmacy profession
iii. The first school of pharmacy was established in 1821 founded by the
United States and now it is as called Philadelphia College of Pharmacy
and Science
iv. Professional guilds led to the training of chemists and pharmacists which
led to the rise of formalized universities and professional organizations.
b) Until the 19th century physicians typically owned the dispensary that
distributed drugs to patients.
ii. The rapid change from hand method to machine method happen. From
production – it is more on methods that uses machines. As the time
passes by pharmacist became more technologically oriented.
iii. Large scale drug manufacturing begin in the society wherein patent are
existed.
1. Patent drugs – they are the only one who produce a specific type
of drug.
2. Example: Digoxin - Lanoxin
2. Regulatory:
a) DOST
b) PDEA
c) Department of Health (DOH)
d) FDA
3. Academe
a) Pharmacy instructors and professors
4. Hospital
a) Primary job or division ideally for pharmacist
i. Because they highlight the job opportunity for pharmacist
5. Community
6. Manufacturing
7. Research
a) For developing new drugs
ii. PHARMACIST
1. REGULATORY
a) Administrative services
b) Manufacturing and packaging
c) Radiopharmaceutical services
2. ACADEME
3. HOSPITAL
a) Administrative services
b) In-patient services
c) Out-patient services
d) Drug information services
e) Sterile product
f) Departmental services
g) Purchasing and inventory control
h) Central supply services
i) IV admixture
j) PTC
4. COMMUNITY
a) Out-patient services
b) Educational and training
c) Purchasing and inventory control
5. MANUFACTURING
a) Pharmaceutical research
b) Manufacturing and packaging
c) Sterile products
d) Assay and quality control
e) IV mixture
6. RESEACH
b) Regulatory
i. Administrative Services
1. Pharmacist develop policies and provide supervision
c) Hospital Pharmacy
i. In-patient services
1. Pharmacist dispense and provide drugs for inpatient
2. They also inspect and control drugs
3. Pharmacist DON’T counsel, Usually physician does (and nurse)
4. Maintain prescription record
v. Departmental services
1. They control and dispense intravenous fluids or IV fluids
2. As well as controlled substances and they coordinates with drug
delivery and distribution system
3. Like central supply services
x. IV mixture
1. Preparation of IV solution admixture
2. They review each admixture for physical, chemical
incompatibilities to see:
a) Soluble
b) Miscible
c) Aggregate
d) Problems in administration
iii. Education
1. Formulation of programs for the needs or updates of profession
iv. Formulary
1. Formulation of formulary
2. Sila ang gumagawa sa hospital formulary
7. FUTURE OF PHARMACISTS
a) HEALTH MANAGEMENT CENTRES INSTEAD OF DRUG
DISTRIBUTION MACHINES
i. For technical innovation counselling of patients. So, instead of just
dispensing drugs there is a help. They want to have wearable sensors and
tracker data. It will help focus on health management using computer
system.
ii. It is not impossible but it is uncertain to be implemented nowadays (it is
like our goal maybe in 2030, 2040, 2050 it can)
iii. The association of pharmacist (HENDI KO MAINTINDIHAN)
e) EXPANSION OF PHARMACOGENOMICS
i. Related to no. 3
ii. We have the personal healthcare using genetic testing. Result of
sequencing the genome which can be use to link a person’s gene with
personalized specific treatment to improve overall health
iii. The patient holds the opportunity to with the pharmacist and select the
best drugs based on their DNA profile. (here, they like to group the
patients and check the DNA profile and categorize to know the drug that
suits. They’ll check your diseases and learn based on your genes. For the
drug to become suitable and doesn’t have side effects and become really
effective)
f) TARGETING COMPLIANCE AND ADHERENCE TO BIG DATA
i. We all know that data is an effective focus adherence or the compliance.
Retrospective data cannot use data like past history of patients. Drugs
will be given based on their present case. It is updated and continuous.
There will be an availability of real time data which promotes
compliance and the guardians also be inform
8. FUTURE PHARMACIST
a) ROLE OF ARTIFICIAL INTELLIGENCE
i. with the used of smart machines or robots
ii. uses computers that…. (bilis ni ma’am magsalita guys hahahaha kaiyak)
c) HEALTHCARE TEAM
i. Health care is a collaborative effort between physicians, nurse
practitioners, dentists, vets, nurses, and pharmacist.
ii. Paraprofessionals like pharmacy technicians, physician assistants, dental
assistants, hygienists, vet assistants, and licensed practical nurses assist
professionals in routine but necessary tasks.
iii. Pharmacy technicians assist pharmacist allowing pharmacists more time
to meet the mission of the profession: to ensure positive outcomes for
drug therapy in patient population.
Sabi ni ma’am sa dulo if you have any concers just message me in our gc
HAHAHAHAH may discussion daw na Part 2 nextweek :)
1. SOCIAL AND BEHAVIORAL ASPECTS OF PHARMACY
a) Relationship Between Social Inequalities and Health
2. SOCIAL INEQUALITY
a) refers to relational processes in society that have the effect of limiting or
harming a group`s social status, social class, and social circle
b) Unhealthy relationship within a community or group due to some adversities
c) SOCIAL STEREOTYPING
i. Having a fix ideas about people
ii. They are close-minded
d) DISCRIMINATORY LEGISLATION
i. For example, friends or relatives are the one accepted in the government
or public institution
ii. Or they follow the role which is “whom you know, not what you know”
- rules about priorities, not equal
e) WEALTH
i. Rich people are prioritized and have advantage than poor people
f) RACE
i. For example, in US there are still racist (white people have more
advantage, they bully black people)
g) GENDER
i. Sometimes, in institution or establishments there are preferences. For
example, they don’t accept LGBTQ, they prefer men in a specific work
than women
3. HEALTH INEQUITIES
a) these are the factors that affect medical services quality. It is focus on
physicians, but then it relates to other medical practitioners because their
ideas are the same
c) PATIENT COOPERATION
i. It repels noncompliance. When there is a compliance, the medical
personnel is effective and thus the patient will be treated properly.
Remember that the quality of medical services does not only depend on
the capabilities of the medical practitioners but also the cooperation of
the patient.
d) PATIENT ILLNESS
i. Severe illness causes anxiety and stress among staff especially deaths
ii. If a patient die, you feel that it is your fault
i. Recognition
1. What motivate a medical practitioner
a) Promotion
b) Acknowledgement when something is achieve
2. Some institution have:
a) Best employee of the week, month or year
3. This are the factors that will encourage us to work harder
v. Chances of promotion
1. As what I said kanina, we tend to take masteral, doctoral, doctorate
for promotion
ii. Autonomous
1. the ability to work on tasks by themselves with very little help
2. You are independent and responsible enough
3. You can accomplish something or what your boss tell you from the
amount of time given to you
iii. Humble
1. it`s important to stay grounded and not too arrogant
2. *do not fight with the patient, even though they are angry just smile
a) You don’t know what are they going through with their life
iv. Passionate
1. they have an incredible amount of passion for what they are doing
2. They work not only for money but love their work
v. Confident
1. confident employee will take risks because they believe in
themselves
2. They believe in their capabilities
3. Not to brag what they know but they practice the skill form what
they develop through experiences
4. Experiences make people grow and its what makes you, you
5. Have healthy confident
vi. Honest
1. nobody likes a liar.The perfect employee always speaks the truth
2. Quotes:
a) Honesty denotes truthfulness
b) “Honesty id the best policy” (William Shakespeare)
c) “if I lose my honor, I will lose myself”
3. This is very important especially when you counsel patients
4. Paghindi mo alam ung gamot, pwede namang kayong yumingin sa
libro
a) “Maam wait lng po, I will confirm it, I will check it if ganito
ganyan”
vii. Creative
1. look for the employee who asks unexpected questions
2. That’s for innovation
3. For smooth work flow of organization
4. It is best to suggest and recommend
viii. Reliable
1. someone you can always count on, no matter what
2. Responsible, obedient, and has initiative
ix. Eager
1. an ideal employee will be eager and hungry always wanting to learn
new things
2. Training
3. Seminar
x. Positive
1. having a positive attitude especially when times are rough
2. Being optimistic
a) When there is a problem, you can think of a solution without
being depress
b) Thinking ahead
xi. Personal Qualities
1. Have a good memory
a) You have organized work because you have good memory
2. Enjoy learning about new medications & treatments
3. Be trustworthy & detail oriented
4. Good communication skills
5. Good problem solving abilities
i. Enjoy people
b) MOTIVATION
i. WHAT MOTIVATES AN EMPLOYEE?
1. Peers
2. Salaries/wages
3. Incentives/benefits
4. Awards and other recognition
c) EMPOWERMENT
i. Empowering Approach?
1. “Empowerment occurs when the practitioner’s goal is to increase the
capacity of the client to think critically and make autonomous,
informed decisions…it also occurs when clients are actually making
autonomous informed decisions”
a) Empowerment IS TO Adherence
b) Empowerment is a process and an outcome
c) No empowerment without respect
3. “Let’s decide together what is the best care for your conditions.”
a) An agreement designed to support the promotion of self-
management, taking into account the patients’ perspectives on
their condition, their goals, expectations, and needs.
5. This are the opportunity motivational power that are given to any
employee that embodies freedom to choose and gain control of their
resources skills competence but with corresponding accountability.
iii. Empowered Patients – “Own” Their Health Condition
1. Have skills for making decisions and changes as needed
a) Make decisions and direct their life in a way that helps them
meet their goals
3. Self-Management Education
a) Teaches problem solving
b) Helps patients identify problems, make decisions, take actions
d) PATIENT COMPLIANCE
i. Compliance
1. “You must do what I tell you.”
2. An authoritative act designed to reduce patient autonomy and
constrain freedom of choice.
2. BAD
a) Unhelpful when it leaves us feeling
i. Fatigued
ii. Tense
iii. Anxious
iv. Burnt out
v. Overwhelmed
2. WORK/OCCUPATION
a) Full loads of work
3. ILLNESS
a) If you have family members who are in pain or sick or even
yourself.
5. THE NEWS
a) Negative news about what happens nowadays
ix. Behavior
1. Withdrawn from others
2. Do not want to socialize
3. Increase alcohol, nicotine and/or drugs intake
4. Under eat or over eat
5. Accident prone and careless
6. Impatient
7. Aggressive or compulsive (pacing, fidgeting, swearing, blaming,
throwing, hitting)
8. Work longer hours
9. Headless chicken under pressure
10. Manage time poorly
11. No time for leisure activities
x. Feelings
1. IRRITABLE
2. ANGRY
3. DEPRESSED
4. JEALOUS
5. RESTLESS
6. ANXIOUS
7. UNREAL OR HYPER ALERT
8. UNNECESSARY GUILTY
9. PANICKED
g) CONCLUSIONS
i. A combination of environmental and genetic factors contribute to mental
illness
ii. Mental disorder are not caused by personal laziness or weak character.
iii. It is actually an illness that have causes
c) TYPES OF THINKING
i. CREATIVE THINKING\
1. Devising or formulating, innovating ways or solutions, - these are
the exploration of the mind / exploring many, usually from
brainstorming
2. Approach: more relax, simple, open and playful
ii. AWARENESS
1. Knowledgeable, reads a lot of books and updates
iii. CURIOSITY
1. Always curious about everything. They are researchers
iv. OPEN-MINDEDNESS
1. If the problem arises, they doesn’t focus only on one factor but
considers a lot of factors
v. HONESTY
1. Fratch (prangka)
vi. PERSEVERANCE
1. You don’t stop in one thing only
vii. RESOLUTENESS
1. Always stand for what you believing
viii. AUTONOMY
1. Independent
ix. EMPATHY
1. Understand and accept the perspective of other peoples
x. CREATIVITY
1. Creativity on how they innovate and formulate drugs
e) CRITICAL THINKERS
i. Are honest with themselves, acknowledging what they don't know,
recognizing their limitations, and being watchful of their own errors.
ii. Regard problems and controversial issues as exciting challenges.
iii. Strive for understanding, keep curiosity alive, remain patient with
complexity, and are ready to invest time to overcome confusion.
iv. Base judgments on evidence rather than personal preferences, deferring
judgment whenever evidence is insufficient. They revise judgments
when new evidence reveals error.
v. Are interested in other people's ideas and so are willing to read and listen
attentively, even when they tend to disagree with the other person.
vi. Recognize that extreme views (whether conservative or liberal) are
seldom correct, so they avoid them, practice fair-mindedness, and seek a
balance view
vii. Practice restraint, controlling their feelings rather than being controlled
by them, and thinking before acting.
viii.
COMMUNICATION
● This also topic for interpersonal communication
● It is an exchange of information from one individual to another individual/s
● It’s a way in delivering information
1. Sender
⮚ Sends the message
⮚ Aka: encoder
2. Message
⮚ Most important element because it’s the information to be relate/relay
between the sender and receiver
3. Receiver
⮚ They receive the massage
⮚ They translate
⮚ Aka: decoder = decoder of the massage
EFFECTIVE COMMUNICATION
● Effective communication skills or effective communication must be practice by
different medical practitioner when they interact with the patient in order to
make the intervention more effective.
TYPES OF COMMUNICATION
1. Verbal
⮚ This is when you deliver messages through conversation of face to face
2. Written
⮚ Written instructions or you write the instruction
⮚ Example:
▪ Writing memos
▪ letter
3. Nonverbal
⮚ how you express the message, information, or opinion
▪ gesture,
▪ mannerism,
▪ facial expression and
▪ Body language
▪ Tone of voice
ELEMENTS OF EFFECTIVE COMMUNICATION
1. The message must be clear
⮚ Example: counseling the patient
▪ You have to be clear and understandable
▪ don’t say “This is antipyretic” instead “this is for fever”
2. The sender must deliver the message in a clear and concise manner
⮚ Complete and detailed
⮚ Simple and short but understandable
LISTENING
● Is essential for communication,
● attempt to hear what others are saying
● A good listening skill techniques observe speaker closely, reflect statement
made by the speaker back to them
● Listen also to the nonverbal action of the patient in order for you to know what
the information the patient thoroughly conveying.
BARRIERS TO COMMUNICATION
Common barriers
1. Physical disabilities
⮚ Hearing impaired
▪ Need written instruction or accompanied by guardian
2. Environment
⮚ Noise
⮚ temperature
3. Psychological attitudes and prejudice
⮚ Personal opinion
▪ Whatever you say, the patient will still answer you according to their
belief
4. Cultural diversity
⮚ Actually look the same as Psychological attitudes and prejudice
▪ Belief
▪ tradition
GOOD COMMUNICATION
1. When there is good communication everywhere of course people will never
have to misunderstand or misinterpret
⮚ Walng nadadagdag, Walng nababawas
2. In hospital, when the patient are open to share their information and
honest in explaining their medical history
⮚ Mas maganda ung intervention na maibibigay sa kanya
⮚ if the patient is open to share their information, the intervention will be
more effective
4. If the health care team are also open to share ideas, suggest and recommend
and open to changes it make the institution be better
5. REMEMBER “GOOD
COMMUNICATION
ESTABLISH TRUST”
⮚ Good communication skills allow development of good interpersonal
relationships
⮚ Health care worker also relates more effectively with coworkers and
other individuals
1. SERVICE -
⮚ Make serving others your number-one priority.
⮚ Great customer service happens when you exceed customers’
expectations by adding your special touch and by having the courage
to make things right.
⮚ You have to be service oriented and not profit oriented
⮚ If you treat patient right, hahanap hanapin ka niya, hahanap hanapin ka
niya kahit lumayo ka, thats true actually in physician
2. ATTITUDE - Choose your attitude. How you think about the customer is
how you will treat them.
⮚ A shining attitude is contagious around customers and shows in
the quality of your work.
⮚ Service and attitude is quite related
3. Tend to issues encircling the patient, pharmacy store and the physician
who prescribed the medication/s
⮚ If there is concerns regarding on what the physician prescribe, then you
should call or contact him (doctor or physician) and ask him nicely
⮚ Example:
▪ Ibuprofen 500mg (in the prescription) but There is only 2 dosage
strength which is 200 mg and 400 mg. What will you do?
o don’t call him wrong
o Doc wala pong 500 mg na ibuprofen, ang available lng po ay 200
and 400 mg.
⮚ There is instances where nagkakamali rin sila sa dosage strength
INTERPERSONAL COMMUNICATION
● It circle about personal and relational ideas or opinions between people
● It counts and check about the attitude toward what was said or what was
conveyed
▪ communication between two people
▪ came to being when men began to exchange ideas and thoughts to one
another
▪ a kind of communication in which people communicate their feelings,
ideas, emotions and information face to face to each other
▪ It can be in verbal or non-verbal form
▪ Not only about what is said and what is received but also about how it is
said, how the body language used, and what was the facial expression.
⮚ It is complicated because of our views towards other person and our behavior
and traditions are all parts of the message which makes it complicated.
⮚ Example:
- you are talking with your friend and you have different views and
opinions then maya-maya may galit na sa isa sa inyo.
⮚ Parts of communication:
✔ Who do you think you are?
✔ Who you think the other person is?
✔ Who you think the other person think you are?
✔ Who the other person thinks to other person she/he is?
✔ Who the other person think you are?
✔ Who the other person thinks you he/she is?
4. Interpersonal communication is contextual
⮚ In other words, communication does not happen in isolation. There is:
● Psychological context,
o which is who you are and what you bring to the interaction.
o Your needs, desires, values, personality, etc., all form the
psychological context. ("You" here refers to both participants
in the interaction.)
● Relational context,
o which concerns your reactions to the other person--the "mix."
o Reactions that make the conversation complex which concerns
your reaction to the other person
● Situational context
o deals with the psycho-social "where" you are communicating.
An interaction that takes place in a classroom will be very
different from one that takes place in a bar.
o Different topic with different place
o Ang pinag-uusapan sa loob ng Bahay ay di dapat pag
usapan sa labas
● Environmental context
o deals with the physical "where" you are communicating.
o example:
▪ Furniture
▪ location
▪ noise level
▪ temperature
▪ season
▪ time of day
▪ all are examples of factors in the environmental context.
o It talks with environmental factors
● Cultural context
o includes all the learned behaviors and rules that affect the
interaction.
o If you come from a culture (foreign or within your own
country) where it is considered rude to make long,
o example:
▪ direct eye contact, you will out of politeness avoid eye
contact.
▪ If the other person comes from a culture where long,
direct eye contact signals trustworthiness, then we
have in the cultural context a basis for
misunderstanding.
v. Amended by RA 5921
1. Former Pharmacy Law
2. We now have 10918
2. DISPENSING
a) Act by a validly-registered pharmacist of filling a prescription or doctor`s
order/ medical`s order on the patient`s chart
b) Responsibility or function of the pharmacist in filling up the prescription
in giving the prescribed drug to the patient
3. GENERIC DISPENSING
a) dispensing the patient`s choice from among generic equivalents
b) If the prescribed drug isn’t available tell the patient the available drug with
the same generic name, same active ingredient, same dosage form, same
strength as the prescribe drug. Then, the patient will choose.
c) You don’t recommend, you just give the choices
4. PARTIAL FILLING
a) dispensing less than the total number of units prescribed
b) If the physician prescribe 6 tablets of paracetamol and you don’t have
enough money, so, you just bought 3. Partially filled will be indicated in
the prescription. The pharmacist will return the prescription to the patient.
c) There are fully filled, it will be kept in the drug store
c) Prescription keeping
i. prescriptions shall be kept for 2 years and should be recorded in a
prescription book registered by FDA which shall be open for inspection
by FDA at anytime during business hours.
ii. Fully filled prescription will get by the drugstore or the pharmacist to be
kept and record in the prescription book, that should be kept for 2 years.
Anytime it should be available because FDA will inspect
iii. Prescriptions filled should be kept for two years and recorded in a
prescription book
c) HOSPITAL PHARMACIES
i. Individually informing the buyer on the available generic equivalents of
the drug prescribed and their corresponding price.
1. Corresponding price
a) there is a handbook in hospital pharmacy containing this
information and it should be available in every ward and
hospital room
ii. Prescriptions filled should be kept for two years and recorded in a
prescription book
d) HOSPITAL PHARMACY
i. The drug products in unit dose transferred in small bottles should contain
the following information
1. Name of the patient
2. Generic name of the drug
3. Brand name (if any)
4. Manufacturer
5. Dosage strength
6. Expiry date
7. Directions for use
8. Name of the pharmacist
e) HOSPITAL PHARMACY
i. In partial filling of prescription, the following should be written on the
face of the prescription
1. Date of partial filling
2. The quantity served and balance of the prescription unserved
3. Name and address of the drugstore
4. Stamp
a) name of the hospital or drugstore and address
ii. The partial filled prescription shall be returned to the buyer after
recording the partial filling in the prescription book. The drugstore which
completes the filling should keep the prescription.
f) HOSPITAL PHARMACY
i. In dispensing drugs included in
1. List A
a) (PROHIBITED AND REGULATED DRUGS) and
2. List B
a) ( DRUGS REQUIRING STRICT PRECAUTIONS IN
THEIR USE) attached as Annex 1 and 2 respectively:
i. It can also be drugs of abuse aside from dangerous drug and
with narrow therapeutic index (digoxin)
a) GENERIC NAME
i. non-proprietary name based on the chemical name of the drug
ii. the identification of drugs and medicines by their scientifically and
internationally recognized active ingredients or by their official generic
name as determined by the FDA of the DOH
b) ACTIVE INGREDIENT
i. chemical component responsible for the claimed therapeutic effect of
the pharmaceutical product
c) CHEMICAL NAME
i. description of the chemical structure of the drug or medicine and serve
as the complete identification of a compound
ii. If it is amine, phenol, carboxylic acid
iii. Basis for its generic name
d) DRUG PRODUCT
i. finished product form that contains the active ingredients, generally
but not necessarily in association with inactive ingredients
e) DRUG ESTABLISHMENT
i. any organization or company involved in the
1. Manufacture
2. Importation
3. repacking
4. distribution of drugs or medicines
f) DRUG OUTLETS
i. means drugstores, pharmacies, and any other business establishments
which sell drugs or medicines
h) CORE LIST
i. list of drugs that meets the health care needs of majority of the
population, usually the prescripted drugs
i) COMPLEMENTARY LIST
i. a list of alternative drugs used when there is no response to the core
essential drug or when there is a hypersensitivity reaction to the core
essential drug or when, for one reason or another, the core essential drug
cannot be given.
1. ex. OTC drugs like (di ko maintindihan), herbal drugs in
combination and chemicals..
2. Serve as alternative for core list
j) BRAND NAME
i. the proprietary name given by the manufacturer to distinguish its
product from those competitors
ii. Doesn’t base on the chemical name or anything
k) GENERIC DRUGS
i. drugs not covered by patent protection and which are labeled solely by
their international non-proprietary or generic name
ii. Not patented means anyone can produce the drug
iii. Patented means only one manufacturing company, sole manufacture
of specific drug
1. Ex. (di ko maintindihan) digoxin, lanoxin
2. Expire for 7-20 years. Doesn’t apply again because it is expensive.
Other manufacturers can now release their generic drug
10. SECTION 7
a) ADMINISTRATIVE SANCTIONS
i. Suspension or revocation of license to operate (LTO) the drug outlet by
the Secretary of Health
ii. Secretary of Health report to PRC (Professional Regulation
Commission)
2. GOVERNMENT BODIES
a) The Philippine Drug Enforcement Agency or Prohibited Drug
Entrapment Agency (PDEA)
i. is the lead anti-drug law enforcement agency, responsible for
preventing, investigating and combating any dangerous drugs,
controlled precursors and essential chemicals within the Philippines
a) Alfentanyl * pethidine/meperidine
b) Codeine
c) Dihydrocodeine
d) Fentanyl
e) Hydrocodone
f) Morphine
g) opium
b) Regulated Drugs
i. barbitals, benzodiazepines and amphetamines (anxiolytic and sedative)
1. Sedative- pampa kalma
a) Amobarbital * diazepam
b) Amphetamine * nitrazepam
c) Phenobarbital * paraldehyde
d) Pentazocine
e) Dexamphetamine * pentothal
f) Ephedrine * propoxyphene
g) Ethinamate * pseudoephedrine
5. DRUGS OF ABUSE
a) TOLERANCE
i. to a physiological state where the effectiveness of a drug has decreased
due to chronic administration.
1. Example: once mo siya lagi tinetake and then ngayon dahil lagi mo
siyang tinetake ng once sa susunod kailangan mo ng taasan yung
dose pwedeng twice na.
b) DEPENDENCE
i. Refers to how the body experiences physiological adaptation in
response to chronic use of a drug.
ii. This is actually referred to us WITHDRAWAL SYMPTOMS
iii. Dependence ay kumbaga hindi kana mabubuhay kung wala yung drug.
Dependent kana don.
iv. Or for example masakit ulo mo lagi kana magtetake ng ganitong drug
kasi nga yun na yung lagi mong ginagawa.
c) ADDICTION
i. -defined as the compulsive use of drugs for non-medical reasons.
ii. -the individual is likely to have developed physical as well as
psychological dependence on the symptoms.
2. Addiction
a) taking the drug for leisure activities
b) Robitussin DM (Guaifenesin + Dextrometorphan) - they take
this dahil ayaw nila makatulog.
d) RESISTANCE
i. Reduction/loss in effectiveness of a drug if not taken with right
dosage regimen
ii. Examples:
iii. Antibiotic
1. Cephalosporins- there are 4 generations of Cephalosporins
2. For example
a) ang prinescribe ay 3rd generation, yun yung medyo
magkakaroon tayo ng problema kapag hindi yun tinake ng
mabuti kasi lahat na ng 3rd generations Cephalosporin sayo hindi
na magiging effective. That is called ANTIBIOTIC
RESISTANCE
6. DRUGS OF ABUSE
a) CNS STIMULANTSCNS DEPRESSANTS
b) HALLUCINOGENS
c) OPIODS AND OPIATES (AGONISTS AND ANTAGONISTS)
7. CNS STIMULANTS
a) CAFFEINE (COFFEA ARABICA)
i. Sources:
1. COFFEA ARABICA (well known)
a) 1, 3, 7 trimethylxanthein caffeine
b) This is an alkaloid
2. COFFEA ROBUSTA
v. Side Effects:
1. tachycardia
2. palpitations
3. Arrhythmia
4. seizures
5. diuresis ( cathartic / laxative)
6. increase acid secretion
b) NICOTINE
i. Sources:
1. NICOTIANA TOBACCUM
ii. Cigarettes
1. Nicotine is the main component of Cigarettes that causes addiction
2. Tar – causes cancer
c) METHYLPHENIDATE
i. It is the drug use for the treatment of:
1. ADHD – Attention Deficit Hyperactivity Disorder
2. NARCOLEPSY
3. Impulsivity
a) means a person makes hasty actions that occur in the
moment without first thinking about them and that may have
high potential for harm;
b) An impulsive person maybe socially intrusive and excessively
interact others or make important decisions without
considering the long term consequences.
i. Example: impulsive buyer
4. Narcolepsy
a) It is often associated with:
i. sudden sleep attacks,
ii. insomnia,
iii. dreamlike hallucinations and a
iv. condition called sleep paralysis or coma
d) Amphetamine
i. A strong stimulant that speeds up the heart and breathing and dilates the
eyes or mydriasis.
ii. It is a treatment
1. for Attention-deficit/hyperactivity disorder (ADHD)
2. It is also used for the treatment of Hypertension but in low dosage
only
iii. Bypassing all the body’s normal capabilities for creating energy,
amphetamine makes a person feel alert and powerful.
1. Fatigue and hunger go away
2. So Amphetamine abusers does not eat or rest
e) METAMPHETAMINE
i. chronic abusers may exhibit symptoms that can include significant
1. anxiety,
2. confusion,
3. insomnia,
4. mood disturbances, and
5. violent behavior (rage syndrome)
a) if you have this violent behavior there is a possibility that you
can kill a person
b) in short Rage syndrome – your anger can turn you into a
murderer
ii. They also may display a number of psychotic features, including
paranoia, visual and auditory hallucinations, and delusions
iv. Paranoia
1. Involves intense anxious or fearful feelings and thoughts often
related to treat or conspiracy and persecution.
2. Example:
a) you are very afraid because you have the feeling that someone
can kill you
3. You are being paranoid
f) PHENTERMINE
i. It is a stimulant that is similar to an amphetamine
ii. Used as an appetite suppressant that can affect the central nervous
system.
iii. Phentermine is known to treat obesity in people with risk factors such
as high blood pressure, high cholesterol or diabetes.
8. CNS DEPRESSANTS
a) ALCOHOL
i. Synthesis of Alcohol
1. (ethanol) ROH -synthesize by -- OH dehydrogenase -Into -
Acetaldehyde --synthesized in Acetic Acid by aldehyde dehydrogenase
through releasing CO2 and water through burp, flatulence and
diuresis
ii. 1 glass women (14g); 2 glasses men (28g)
1. Moderate drinking ( drink responsibly)
b) COCAINE
i. 1st local anaesthetic from Erythroxylon coca
ii. It is also known as powder, snow, ski, soft, blow, slopes, coca, and
nose candy.
iii. It is normally found as a white, crystalline powder or as an off-white,
chunky substance.
iv. Effects:
1. Euphoria
2. Alertness
3. motor activity
4. and energy
c) BENZODIAZEPINES
i. a class of psychoactive drugs used to treat
1. Anxiety
2. insomnia, and a range of other conditions.
ii. Have a Lesser side effect than barbitals
iii. Effects:
1. Drowsiness
2. poor concentration (over sedation)
a) Acute intravenous administration cause greater decrease of
Respiratory Depression
3. impairment of memory
iv. Antidote:
1. FLUMAZENIL – BENZODIAZEPINE ANTAGONIST
9. HALLUCINOGENS
a) PHENCYCLIDINE
i. Hetamine analog
ii. Sn: Supergrass, Boat, Tic Tac, Zoom,ANGEL DUST,pcp
iii. Used as a Dissociative anaesthesia
1. a unique anesthesia characterized by analgesia and amnesia with
minimal effect on respiratory function.
iv. The patient send to appear and anaesthetize and can swallow and open
his eyes but he does not process information
v. Side effect:
1. Indus aggressiveness
2. Hypertension
3. Psychotic symptoms
d) For :
i. cluster headaches
1. Severe painful headache in short time
2. Series of relatively short but very painful headaches every day, for
weeks or months at a time
ii. depression,
iii. obsessive compulsive disorder
1. Kung may dumi, lilinisan nila
2. Kung may mali sa sinulat, uulitan nanaman nila
3. If they don’t do this, they feel that their live is a mess
iv. severe anxiety in cancer patients
v. MARIJUANA
1. Cannabis sativa
2. Active constituent
a) Delta 9 - THC (tetrahydroxycanabinol)
3. Street names:
a) Dope
b) Pot
c) grass,
d) weed,
e) head,
f) Mary jane
i. Mas kilala sa pinas
g) Doobie
i. Mas kilala sa pinas
h) Bud
i) Ganja
j) Hashish
k) Hash
l) bhang.
4. Dronabinol
a) man-made form of cannabis
b) Tx
i. Anorexia
ii. Antiemetic in chemotherapy
e) Side Effect
i. Sedation
ii. Euphoria
iii. Hypertension
iv. Blood shot eye
v. Increase appetite
12. AGONISTS
i) MORPHINE (abv ng kanyang effect)
i. HECk of a DREAM
ii. Histamine release
1. Cause Urticaria or pruritus, bronchoconstriction
iii. Emesis
iv. Cardiovascular
1. Hypotension or decrease blood pressure
v. Depression of cough reflex/decrease GI motility/depress the CNS
vi. Respiratory depression
vii. Euphoria
viii. analgesic
ix. Miosis
x. USES
1. Analgesia (pain or headaches)
a) DOC to moderate to severe pain
2. Diarrhea
a) paregoric or camphorated tincture of opium
3. Poisoning triad
a) Coma
b) pinpoint pupils
c) respiratory depression
xi. Side effect
1. Tolerance
2. Dependence
3. Addiction
13. Meperidine
j) narcotic analgesic
i. Short-term treatment of moderate to severe pain.
k) It may also be used before and during surgery for pain relief during labor and
delivery (to support anesthesia)
l) Prolong term:
i. Cause seizure
2. FENTANYL
a) 80 times more potent than morphine
b) Employed as an analgesic for severe pain only
c) >>TOXICITY – respiratory depression, coma, hypotension, circulatory
failure, convulsions
d) Fentanyl + droperidol (innovar)
i. Dissociative anesthesia
3. NALBUPHINE
a) It can also be used for pain relief before and after surgery and during
childbirth.
b) Also analgesic for treatment and prevention of moderate to severe pain
c) Toxicity: respiratory depression, sedation, and miosis
4. CODEINE
a) AKA 3-methyl morphine / methylated morpine
b) Use as antitussive (cough)
c) Toxicity: bradycardia, severe drowsiness, muscle weakness, miosis
5. METHADONE
a) Methadone reduces withdrawal symptoms in people addicted to heroin or
other narcotic drugs
b) Use as drug addiction detoxification
c) Methadone is used as a pain reliever
d) Toxicity:
i. torsades de pointes
1. Life threatening ventricular trachycardia
6. HEROIN
a) Acetylated morphine / diacetyl morphine
b) More potent than morphine in addictive property
c) Effect: euphoria, constipation, cns depression, nephropathy, severe muscle
and bone aches
d) Decreases kidney function
e) Cough suppressant and antidiarrheal
7. Opioids ANTAGONISTS
a) Antidote for narcotic toxicity
i. NALOXONE
ii. NALTREXONE
iii. NALORPHINE
14. NALMEFENE