MEDICATION: Generic: Chlorothalidone Trade: Thiazide

Classification (Therapeutic/Pharmacologic):
Therapeutic- antihypertensive, diuretics
Pharmacologic -thiazide diuretic
Reference:
Davis drug guide
Indication:
Management of mild to moderate hypertension. Treatment of edema associated w/ HF, renal dysfunction, Cirrhosis
Action:
Increases excretion of sodium and water by inhibiting sodium reabsorption in the distal tube. Promotes excretion of chloride, potassium, magnesium and
bicarbonate. May produce arteriolar dilation
Adverse reactions (most frequent and life-threatening):
Dizziness, drowsiness, hypokalemia Stevens-Johnsons Syndrome
Contraindications:
Hypersensitivity. Some products contain tartrazine and should be avoided in pts with know intolerance. Anuria, lactation
Dose Range:
PO adults 125-2g/day in 1-2 divided doses. Generally given daily but may be given every other day or 2-3 days/wk.
Nursing Implications:
Monitor BP, intake, output and daily weight. Assess feet, legs and sacral area daily for edema. Assess for nausea, vomiting, muscle cramping, confusion, parathesia.

 Nurs. Course Dosage, frequency, Why is Client receiving the Nursing Assessment Unexpected response to Evaluation of medication
 Date Route per MD or NP drug? What is the expected prior and post medication? action related to this
 Pt. Initials order dose appropriate? effect? administration Significant learning client.
experience r/t this medication?
NURS 175 25 mg PO QD Client is taking med for BP Prior – elevated BP
2/3/2021 Ordered by MD Lower BP Post – BP within normal
limits
VR Dose appropriate

 Nurs. Course Dosage, frequency, Why is Client receiving the Nursing Assessment Unexpected response to Evaluation of medication
 Date route per MD or NP drug? What is the expected prior and post medication? action related to this
 Pt. Initials order dose appropriate? effect? administration Significant learning client.
experience r/t this medication?
SN: 4/2017