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Leitlinien und Empfehlungen

Med Klin Intensivmed Notfmed 2018 · 113:33–44 C. Waydhas1,2 · E. Herting3 · S. Kluge4 · A. Markewitz5 · G. Marx6 · E. Muhl7 ·
https://doi.org/10.1007/s00063-017-0369-7 T. Nicolai8 · K. Notz9 · V. Parvu10 · M. Quintel11 · E. Rickels12 · D. Schneider13 ·
Published online: 7 November 2017 K. R. Steinmeyer-Bauer14 · G. Sybrecht15 · T. Welte16
© Springer Medizin Verlag GmbH 2017 1
Chirurgische Universitätsklinik und Poliklinik, Berufsgenossenschaftliches Universitätsklinikum
Bergmannsheil, Bochum, Germany; 2 Medizinische Fakultät, Universität Duisburg-Essen, Essen, Germany;
3
Department of Paediatrics and Adolescent Medicine, Lübeck, Germany; 4 Intensive Care Medicine,
Hamburg-Eppendorf University Hospital, Hamburg, Germany; 5 Unit XVII—Department of Cardiovascular
Surgery, BwZK, Koblenz, Germany; 6 Surgical Intensive Care Medicine and Intermediate Care, Uniklinik
RWTH Aachen, Aachen, Germany; 7 Interdisciplinary Surgical Intensive Care Unit, UKSH Campus Lübeck,
Lübeck, Germany; 8 v. Haunersches Kinderspital, Campus Innenstadt, Munich, Germany; 9 Teaching
Facilities, Akademie, Kreiskliniken Reutlingen GmbH, Reutlingen, Germany; 10 Deutsche Interdisziplinäre
Vereinigung für Intensiv- und Notfallmedizin e.V., Berlin, Germany; 11 Centre for Anaesthesiology,
Emergency and Intensive Care Medicine, Universitätsmedizin Göttingen, Göttingen, Germany;
12
Neurotraumatology, Allgemeines Krankenhaus Celle, Celle, Germany; 13 Internal Medicine, Neurology
and Psychiatry, Department of Anaesthesiology and Intensive Care Therapy, Universitätsklinikum Leipzig
AöR, Leipzig, Germany; 14 Brühl, Germany; 15 Deutsche Interdisziplinäre Vereinigung für Intensiv- und
Notfallmedizin e.V., SIN mbH, Berlin, Germany; 16 Department of Pneumology, MHH Hanover, Hannover,
Germany

Intermediate care units


Recommendations on facilities and structure

The recommendations of the German In- Definitions


Electronic supplementary mate-
terdisciplinary Association for Intensive
rial
Care and Emergency Medicine (DIVI) on There has not yet been a generally or
The online version of this article (https://doi. the capacity, equipment and structure of internationally binding definition of in-
org/10.1007/s00063-017-0369-7) includes these units are intended to provide the termediate care or of an IMC. An IMC
the following appendices: GNPI statement framework for the setting up and op- is intended to be a unit where those pa-
on structure of paediatric IMCs, Inclusion
eration of IMCs in collaboration with tients are treated that do not require the
criteria, and Research strategies. The article is
available at http://www.springermedizin.de/ experts on both an evidence-based and resources of intensive care unit (ICU), but
mk-im. The videos can be found at the end of an expert-based basis (where scientific are too ill or on too high maintenance for
the article under “Supplementary material”. evidence is not available). Where only treatment on an SCU. The English defi-
minimal or indirect evidence is avail- nition of intermediate care, which refers
able, patient safety is paramount in the to high-maintenance, usually elderly pa-
Introduction formulation of the recommendation. In tients in transition from the inpatient to
the unanimous view of all DIVI represen- outpatient sector and corresponds best to
A growing number of patients with in- tatives, this has the highest priority for short-term care (Kurzzeitpflege) in Ger-
creasingly complex or specialised dis- those entrusted with intermediate care many, is explicitly not intended here.
eases are being treated in German hos- of critically ill and at-risk patients. It is important, therefore, to distin-
pitals. The treatment requirements of guish the IMC from both the ICU and
some of these patients are exceeding the Target group the SCU:
capacity of standard nursing units. How-
ever, the severity of these diseases or the The recommendations on the structure Definition of intermediate care
treatment requirements for these specific and equipment on IMC apply to adult unit
clinical pictures do not always justify ad- patients. The opinion of the German
mission to an intensive care unit (ICU). Society for Neonatology and Paediatric The IMC is suited to the monitoring and
For this reason, an increasing number Intensive Care Medicine (GNPI) can be treatment of patients with moderate or
of special units (intermediate care units, found in Appendix 1 (Electronic supple- potentiallysevere instabilityofphysiolog-
IMC) are being set up to offer highly mentary material). ical parameters that require equipment-
specialised treatment and close moni- based monitoring and organ support, but
toring, in order to fulfil an intermedi- do not require organ replacement. This
ate role between the standard care unit includes patients that require less than
(SCU) and the intensive care unit (ICU). normal intensive care, but more than is

Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018 33


Leitlinien und Empfehlungen

possible on the SCU [1, 2]. The IMC no concrete risk of a life-threatening or d. Conditions requiring a high level of
is not intended to replace an ICU. Of organ-threatening disorder. care
course, there may be overlaps between
these two forms of unit; whether cer- Distinction between intensive care “Intermediate Care Unit” can be under-
tain forms of organ support are provided unit, intermediate care unit and stood as an umbrella term for various
on an IMC rather than on an ICU may standard care unit labels or names that correspond to the
depend on considerations such as those above assessment framework. Such la-
detailed below. It is evident from the above-mentioned bels include:
The task of the IMC is to care for definitions that there is a continuous 4 Coronary Care Unit/Chest Pain Unit
patients whose treatment is so intensive spectrum of disease severity and treat- 4 High Dependency Care Unit
and/or complex that they require con- ment requirements in the crossover 4 Intermediate Care Unit
stant or close monitoring. These are pa- between the three units and a clear dis- 4 Post-Anaesthesia Care Unit
tients whose conditions suggest possible tinction is generally not possible. Among 4 Step-Down Unit
failure of one or more organs, or whose other factors, the allocation of patients 4 Stroke Unit
conditions are too serious or unstable to units also depends on the relevant 4 Vascular Assist Device (VAD) Unit
after failure of one or more organs for structures and facilities and, thus, on
a return to a SCU and who, therefore, the resources available to the hospital or The recommendations discussed below
require continuous monitoring. This in- unit. relate to a general IMC according to the
cludes prevention, diagnosis and treat- For example, the personnel on the above-mentioned inclusion and exclu-
ment of all medical and surgical diseases SCU and their qualifications (including sion criteria for treatment on an IMC.
that could lead to the failure of vital night-time personnel), its technical re- These need be adapted to local require-
functions. The IMC also offers highly sources (basic ECG monitoring, non- ments and conditions and the focus of
specialised treatment, such as neurolog- invasive blood pressure measurement, each unit. If more extensive services are
ical or cardiology treatment (stroke unit, pulse oximetry with central monitoring offered on an IMC, staffing and structural
coronary care unit, etc.), to ensure the and alarm function), structural layout arrangements need to be increased ac-
best possible standard of treatment [3]. (walking distances, audibility of alarms cording to requirements and, conversely,
sounds, physician availability) and the reduced for a less extensive range of ser-
Definition of intensive care unit experience of personnel (e. g. in han- vices.
dling special, intravenously administered The procedure for developing the rec-
The ICU is a specially equipped unit drugs, recognising developing problems) ommendations is detailed in the “Meth-
staffed by specialist personnel to ensure have a significant influence on treatment ods” section at the end of the manuscript.
the medical care of critically ill patients options. In general, there is scant scientific evi-
[4]. The critically ill patient is charac- The crossover between intermediate dence relating to the structure and facili-
terised by life-threatening disorders of one and intensive care may be no less fluid. ties of IMCs. Many recommendations are
or more body systems as a result of disease To which unit should non-invasive ven- therefore based on interdisciplinary and
or injury: tilation be assigned? Is invasive blood interprofessional expert consensus (as set
4 Cardiovascular function pressure measurement or the adminis- out below). A “1C” recommendation, for
4 Respiratory function tration of catecholamines possible on an example, corresponds to a strong recom-
4 Central nervous system IMC? This distinction is extremely vague mendation based on an expert consensus.
4 Neuromuscular function in the integrated organisation model (see
4 Kidneys “Organisational forms”). General recommendations
4 Liver Therefore, it is necessary to define spe-
4 Gastrointestinal tract cific admission and discharge criteria. IMC inclusion and exclusion criteria
4 Metabolism In this context, the following criteria
4 Disorders of temperature regulation represent an assessment framework [1, Key statement
4 Haemorrhagic diathesis 2]:
a. Impaired or threatened organ func- Specific admission and discharge/transfer
tion criteria need to be defined to regulate the
Definition of standard care unit transfer between the various levels of care
b. Specialised surgical procedures, con-
(intensive care, intermediate care, standard
An SCU is an area where the patients be- ditions or disorders that carry the risk care). These criteria (for admission to and
ing cared for require the special resources of developing a (potentially) threat- transfer from an IMC) should be bindingly
of a hospital for a procedure or due to the ening dysfunction and therefore agreed in consultation with the adjoining
severity of a disorder, but do not require require close monitoring units (1C).
constant monitoring (or support) of vi- c. Specialised pathological findings or
tal functions; in addition, patients do not laboratory values
require highly elaborate care and there is

34 Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018


Abstract · Zusammenfassung

There is a consensus thateachIMC should analysis [BGA] equipment, etc.). Disad- Med Klin Intensivmed Notfmed 2018 ·
develop specific admission and transfer vantages include the cost of basic equip- 113:33–44
https://doi.org/10.1007/s00063-017-0369-7
criteria [1, 5, 6]. ment for each patient bed; the loud and
© Springer Medizin Verlag GmbH 2017
In addition to the general criteria for turbulent environment of an ICU for in-
the admission or transfer of patients, spe- termediate care patients that are awake;
C. Waydhas · E. Herting · S. Kluge ·
cific criteria can be applied for certain the difficulty of categorising patients as A. Markewitz · G. Marx · E. Muhl · T. Nicolai ·
units, which take into consideration the intensive care or intermediate care due to K. Notz · V. Parvu · M. Quintel · E. Rickels ·
treatment of specific diseases (e. g. Stroke the various influences and interests; and D. Schneider · K. R. Steinmeyer-Bauer ·
Unit, Coronary Care Unit) or treatment the potential for conflict when it comes to G. Sybrecht · T. Welte
situations (e. g. Weaning Unit). These bed allocation on interdisciplinary units. Intermediate care units.
specific criteria (see Special Section) can The possible advantage of flexible per- Recommendations on
directly affect the structure and facilities sonnel management can be highly de- facilities and structure
ofthe respective unit, whichmaylie above manding and may also be subject to the
(or possibly below) the requirements of influence of various conflicts of interest. Abstract
a general IMC. A growing number of patients with
Parallel model on an intensive care unit increasingly complex or specialized diseases
are being treated in hospitals worldwide.
Organisation [7, 8]. ICU and IMC are separated into The treatment requirements of some of
defined areas with differing facilities, but these patients are exceeding the capacity
Organisational forms are adjacent to each other and can access of standard nursing units. However, the
the same resources. Advantages include: severity of these diseases or the treatment
the common use of (technical) intensive requirements for these specific clinical
Key statement pictures do not always justify admission
care resources (ultrasound, ECG, defib- to an intensive care unit. For this reason,
The organisational form recommended is rillator, transport ventilator, BGA, etc.); an increasing number of special units
either an integration model within an ICU or a common administration; the constant (intermediate care units) are being set up to
a parallel model adjacent to an ICU (with offer highly specialized treatment and close
presence of readily available physicians;
common management) or a stand-alone IMC. monitoring, in order to fulfil an intermediate
The choice of organisational form should be high flexibility in the exchange of nursing
role between the standard care unit and the
chosen according to local factors (1C). personnel between IMC and ICU; uni- intensive care unit. The recommendations
fied medical and nursing management of the German Interdisciplinary Association
Due to the particular factors in heart with uniform standards and treatment for Intensive Care and Emergency Medicine
surgery, other organisational forms may paths; simplified qualification measures (DIVI) on the personnel, capacity, equipment
also be considered and implemented [7]. for IMC personnel; excellent treatment and structure of these units are intended to
provide the framework for the setting up
A prerequisite of this is compliance with continuity in the transfer between ICU and operation of intermediate care units
the personnel, equipment, layout and or- and IMC with little loss of information; in collaboration with experts on both an
ganisational requirements cited in this a short transfer distance between IMC evidence-based and an expert-based basis
recommendation. and ICU; the possibility of joint moni- (where scientific evidence is not available).
toring (a single, central office); immedi- Where only minimal or indirect evidence is
available, patient safety is paramount in the
Integration model in an intensive care ate support from ICU personnel for IMC formulation of the recommendation.
unit [7, 8]. On a combined unit, intensive personnel in medical emergencies; and
care and intermediate care patients are simplified patient allocation, with uni- Keywords
treated together. The formal allocation to fied medical and nursing management Organization · Personnel · Medical staff ·
one or other category is made using a list and improved admission capacity for in- Equipment
of criteria. The advantages here lie in tensive care. Possible disadvantages in-
extremely high flexibility in terms of the clude: the need to move patients between
assignment of personnel (service plan- ICU and IMC (transfer to another room); space, organisation and staff. In addition
ning) and the option of flexible (short- the risk of misallocation of patients on to its clear structure, consistent treat-
term) personnel management and flex- an IMC that should have been treated ment paths are seen predominantly as
ible care: nurse:patient ratio. Adjusting in an ICU (insidious development of an strengths. This model represents a good
treatment to patient needs is straight- intensive care situation with a poor per- solution if there are structural restric-
forward and patients do not need to be sonnel:patient ratio); a possible lack of tions in the ICU. It can also be useful as
transferred if their status changes. This access to certain hospital departments a specialised treatment unit in buildings
can reduce the loss of information and and a possible conflict in bed allocation without their own ICU. However, it must
ensure optimum continuity of treatment. if intermediate care is interdisciplinary. not be used as a replacement ICU, but
A physician is permanently present. It is rather there should be an agreement
not necessary to make two sets of equip- Independent intermediate care unit with ICUs at other institutions to ensure
ment available (ultrasound, ECG, defib- (stand-alone) [7, 8]. This IMC is de- that patients meeting the criteria for
rillator, transport ventilator, blood gas fined as an independent unit in terms of intensive care can be transferred at any

Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018 35


Leitlinien und Empfehlungen

time. It can be a disadvantage that: there Bed numbers 4 Where available: deployment of
is less flexibility for small units in terms a rapid response team or number
of planning nursing rotas; very small Key statement of modified early warning score
units need to fulfil minimum nursing (MEWS)-triggered alarms
cover per shift with two nurses present; Units with 10–12 beds are recommended for 4 Mortality in the case of selected
there may be a lack of continuity in the stand-alone IMC wards. An integration or diagnoses (e. g. sepsis, pneumonia,
parallel model is preferable for lower bed
transition from and to the ICU with loss pancreatitis, coronary infarction,
numbers. Bed requirements should be
of information; and personnel may have individually determined for each institution. stroke, femoral neck fracture)
more difficulty qualifying in intensive Structural, organisational and facility
care needs. Units of this kind require requirements must be fulfilled irrespective of At least 10–12 beds are recommended for
a full technical infrastructure of their bed numbers (1C). stand-alone wards [3, 5, 6, 10]. It makes
own (ultrasound, ECG, defibrillator, little economic sense to equip smaller
transport ventilation, BGA, etc.). It may Scientific evidence on medically recom- units with the required structure. If the
be further to transport patients between mended bed numbers or unit size is not IMC is linked to another acute medicine
ICU and IMC, with reduced flexibility available (this may also depend on the in- department (e. g. parallel model ICU),
in terms of transfers and higher require- dividual organisational form). Predomi- then bed numbers can be lower [3, 6].
ments for documentation (e. g. transfer nantly organisational and economic con- There is no reliable information on an
reports, handover protocols). siderations can therefore be used here, as upper limit for bed numbers in an IMC.
well as the requirements of special pa- Sizes of 22–28 beds have been estab-
Integration model in, or parallel model tient groups and clinical pictures. The lished. There is a tendency to consider
to, a normal unit [7]. On a joint unit, SCU size of the “unit” is not the same as the very large units more difficult to manage.
and IMC patients are treated together or size of a ward. The latter may be larger Dividing larger units into smaller units
in immediately adjacent areas. The for- and consist of several “units” (see be- of 10–12 beds is recommended.
mal allocation to one or other category is low). However, the required structural,
made using a list of criteria. Advantages personnel and facility criteria must be
include: easier transfer between IMC and fulfilled irrespective of bed numbers.
SCU; greater incentive for nursing per- For patients undergoing cardiac pro-
sonnel on the SCU to gain higher quali- cedures, 0.75 beds per 100 procedures
fications; and better and easier control of involving a heart–lung machine are rec-
patient flow in a department with many ommended [7]. Various different cal-
high-risk patients. Set against this is the culation models have been described in
risk of lower staff qualifications, espe- a DGAI position paper, although these
cially poor or lacking skills in intensive have not been validated (in [9]). It is
care nursing; longer transfer distances not possible to make a generally valid
between IMC and ICU; lack of conti- recommendation on the required num-
nuity during transfer between IMC and ber of beds. Local requirements must be
ICU with loss of information; possibly determined for each institution. For ex-
poorer physician availability and the lack ample, the following parameters can be
of a designated, continuous unit director; used to calculate requirements.
prompt management of emergencies may 4 Number of patients treated as inpa-
be hampered and acute patient deterio- tients in the hospital as a whole
ration may ensue; and finally, difficult- 4 Disease severity of patients treated as
to-implement personnel exchanges be- inpatients (e. g. case mix index)
tween IMC and ICU with the possibility 4 De-registration or refusal rates due
of loss of competence over time. to a lack of ICU beds for surgical
procedures, emergency patients,
transfers from other hospitals, etc.
4 Rates of “mis-allocation” of patients
not requiring intensive therapy to
ICUs
4 Rates of (unplanned) transfer from
SCUs back to ICUs due to complica-
tions
4 Excessive demands (on staff) and
undertreatment (of patients) on
SCUs

36 Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018


Range of services offered by ity for severely ill or at-risk patients is bronchial toilet, the clinical pictures
hospitals with an IMC and their based on a medical assessment regarded to be treated, frequently performed
(24 h) availability as equally necessary by numerous na- procedures) [5]
tional and international specialist soci- 4 Regulation of visiting hours

Key statement eties and committees [3, 6, 7, 15]. Falling


short of this standard would lead to se- Quality assurance
The following services should be available in rious complications—which can be ex-
hospitals with an IMC (1A): pected in IMC patients and are indeed
24-Hour availability (presence)
Key statement
the rationale behind theirmonitoring and
4 Conventional X-ray Documented and transparent internal quality
4 Computer tomography treatment on an IMC unit—that cannot
assurance should be carried out on the IMC,
4 Bronchoscopy be treated with the due (specialist) and as well as an at least annual report on
4 Ultrasound prompt standard care. performance figures and results and, where
possible, an external quality assurance (1C).
24-Hour availability on site or as
a cooperation model within 30 min Procedures on the unit
4 Interventional cardiology diagnosis and General criteria or parameters and in-
therapy Key statement struments for an external quality com-
4 Surgical capacity for emergency proce- parison of IMCs have not yet been estab-
dures Regulations for medical rounds, instructions lished. Nevertheless, quality assurance
4 Gastroscopy on organisational and uniform medical care measures as established in medicine in
4 Blood bank and competence in transfusion (between ICU and IMC) and visiting hours
medicine general, and in intensive care medicine
etc., need to be specified in writing (1C).
4 Clinical chemistry laboratory in particular, can be carried out. These
4 ICUa include (without any claim to exhaus-
Bothinterms oforganisation and medical tiveness) interdisciplinary and interpro-
Availability within 24 h (on call or as
treatment, an IMC requires clear, con- fessional case conferences, morbidity and
a cooperation model)
4 MRI sistent and thorough regulations for the mortality (M&M) conferences, infection
4 Angiography/digital subtraction angiog- smooth running of the unit. This applies statistics, complication statistics and the
raphy (DSA) to all patients, irrespective of the medical collection of process parameters. Peer re-
4 Neurology speciality responsible for the treatment of view can also be carried out on the IMC.
4 Microbiology
the underlying disease. These regulations With the exception of quality indicators
4 Pharmacy
4 Hygiene cover the entire spectrum of basic care, for ventilation, the quality indicators of
monitoring of vital functions and gen- the Peer Review process in intensive care
Additional services may be necessary eral therapies and prophylaxis. Special- medicine can also be applied on the IMC.
depending on special requirements of the ist departments treating patients on an The basis for this is regular report-
patient collective.
a IMC need to develop a binding consensus ing, which should include data on patient
In institutions without an ICU, provision must
be made for transfer to an ICU elsewhere. for this. Independently of this, specific numbers, patient flow, treatment mea-
medical decisions, particularly those for sures, cost description (e. g. therapeutic
the treatment of underlying diseases by intervention scoring system [TISS]-28,
Key statement
the treating discipline, must be made in or similar) and other items, in addition
In hospitals with an IMC, the following agreement with the medical management to the above information.
specialist medical expertise must be available of the IMC. External quality and benchmarking
(1A): The following regulations in particular instruments have already been estab-
24-Hour availability (presence)
need to be set: lished for specific areas [6, 15, 16].
4 Internal medicine
4 Surgery 4 Regular rounds/consultations of all
4 Anaesthesiology disciplines and professional groups Special recommendations
involved in treatment [1]
24-Hour availability (on call within 30 min) 4 Instructions, standard operating
4 Additional specialist presence may
Admission, exclusion and
procedures (SOPs), algorithms, discharge criteria
be necessary depending on special
requirements of the patient collectivea guidelines or instructions, etc. for
organisational and general areas Key statement
a
For more details, the reader is referred to the (hygiene plans, provisions, responsi-
recommendations of specialist societies or bilities, etc.). The criteria for the admission of patients to an
certification institutions, e. g. Stroke Units [6, IMC, for transfer from an IMC and for patients
4 Instructions, SOPs, algorithms,
10–12] or Chest Pain Units [13, 14]. who should not be placed on an IMC should
guidelines or instructions, etc. for be based on the list below (1C).
medical areas (difficult airway man-
The services maintained by a hospital to agement, sedation/delirium, nutri-
ensure safe treatment of adequate qual- tion, non-invasive ventilation (NIV)/

Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018 37


Leitlinien und Empfehlungen

The use of criteria for the admission of 4 Hypertensive emergency without 4 Hyperosmolar syndrome with in-
a patient to an IMC is strongly recom- evidence of acute organ damage creased risk of coma [1]
mended, as well as criteria on the basis requiring treatment [1] 4 Thyrotoxicosis, hypothyroidism
of which they should not be admitted requiring close monitoring [1]
to an IMC, but instead require intensive B. Respiratory System.
care treatment. It should also be speci- 4 Patients with mild respiratory fail- G. Surgical Conditions.
fied when a patient can be transferred to ure or the risk of deterioration 4 Postoperative patients following
a SCU and when transfer to an ICU is of respiratory failure requiring close major procedures that are haemody-
required. Additional or modified criteria monitoring and/or intermittent respi- namically stable but with an increased
can be defined for specialised IMCs. For ratory support (e. g. NIV/continuous need for volume and transfusion,
units that do not meet the recommended positive airway pressure [CPAP]/high caused by large fluid shifts [1]
standards, the admission criteria must be flow oxygen) [1] 4 Stable postoperative patients but with
modified such that only patients that can 4 Patients who require close checks a high postoperative risk of bleeding
be safely cared for with the available re- on vital parameters or intensive (e. g. following mass transfusion, tak-
sources are admitted. The following cri- respiratory physiotherapy (e. g. ing anticoagulant therapy, bleeding at
teria are recommended largely as a basis tracheal aspiration more often than the end of the procedure)
for the development of the relevant list 3×/day) [1] 4 Postoperative patients requiring close
of criteria. This list also represents a ba- nursing care and monitoring, e. g.
sis for setting requirements in terms of C. Neurological System. following carotid endarterectomy,
structure and equipment for the IMC. 4 Acute neurological–neurosurgical peripheral vessel reconstruction,
picture with the need for frequent V-P shunt revision, kidney transplant
Admission criteria neurological examination or frequent [1]
General. suctioning of the oral cavity or
4 Need for monitoring more than positioning [1] H. Other.
6×/day or every 4 h 4 Disoriented patients requiring close 4 Treated and regressing sepsis without
4 Absence of criteria requiring admis- monitoring and examination for shock or secondary organ failure [1]
sion to ITS signs of neurological deterioration 4 Patients requiring close monitoring
4 Increased need for care [1] of fluid management [1, 20]
4 Stable neurological patients requiring 4 Obstetric patients during pregnancy
The increased need for care could, e. g. cerebrospinal fluid (CSF) drainage or post-partum with (pre)eclampsia
be defined according to the Swiss clas- [1] or other medical problems [1]
sification in categories 2 and 3 (in spe- 4 Patients with chronic neurological 4 Any patient requiring frequent
cial cases also 1A and 1B, if any of the disorders, e. g. neuromuscular dis- monitoring or very complex wound
other criteria below are present) on the ease requiring frequent care measures management that does not fall into
basis of the nine equivalents of nursing [1] any of the above categories (e. g.
manpower (NEMS) and the Richmond Addisonian crisis, acute renal failure,
agitation–sedation scale (RASS) [3]. The D. Poisonings and Overdoses. delirium tremens, hypercalcaemia)
nursing activities score (NAS) offers an- 4 Any patient requiring frequent [1]
other possibility, although this is not cur- neurological, respiratory or car-
rently widespread in Germany [17–19]. diovascular monitoring following Exclusion criteria
poisoning or overdose and that is The following conditions are usually not
A. Cardiac System. haemodynamically stable [1] suitable for admission to an IMC. These
4 Exclusion of acute myocardial infarc- should also be locally defined and may
tion [1] E. Gastro-intestinal Disorders. vary depending on the equipment on
4 Non-ST elevation myocardial infarc- 4 Gastro-intestinal bleeding with mild the unit, the experience of the treatment
tion, haemodynamically stable [1, orthostatic hypotension that reacts to team, the type of patient or the disease
14] volume administration [1] condition.
4 Arrhythmia, haemodynamically 4 Acute ST-elevation myocardial in-
stable [1] F. Endocrine System. farction, acute coronary syndrome
4 Haemodynamically stable patient 4 Diabetic ketoacidosis requiring with haemodynamic instability, tem-
without myocardial infarction, but continuous and constant intravenous porary pacemaker, haemodynamic
requiring a temporary cardiac pace- insulin administration or more instability of other cause, pulmonary
maker [1] frequent insulin injections in the oedema with the risk of an indication
4 Acute heart failure without shock early phase once ketoacidosis has for intubation or the risk of heart
(Killip Class I, II) [1] been controlled [1] rhythm disorders [1, 21]

38 Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018


4 High catecholamine requirements Staffing Swiss guidelines on the recognition of
or sharply varying/increasing dose, IMC [3] for appointed deputies, a spe-
drugs requiring extensive haemody- Medical personnel (number, cialist with 12 months of intensive care
namic monitoring qualification, availability) training or 6 months of intensive care
4 Acute mechanical circulatory support training plus 6 months of training in
[20] Key statement emergency admissions or anaesthesia or
4 Patients with shock (septic, haem- on an IMC are required. Extrapolated
orrhagic, cardiogenic, anaphylactic) A unit director and a deputy should be to the German training regulations, this
[20] appointed. The director should be board would mean, in addition to specialist
certified in intensive care and the deputy
4 Acute dialysis, continuous renal physician status, formally verifiable qual-
should be a specialist with at least 1 year’s
replacement therapy (CRRT) experience in intensive care (1C). ification in the form of evidence of board
4 Patients with acute respiratory failure The director or deputy should do daily rounds certification in intensive care or board
that have recently been intubated or and visit all patients on the unit at least twice certification in emergency medicine or
in whom intubation may be required a day on all normal working days (1C). the anticipated future board certification
The continuous presence of a physician is
[1] in clinical emergency medicine.
required and may be organised at night and
4 Patients with an endotracheal tube weekends in the form of an on-call service in In the past, a continuous medical pres-
4 Patients requiring extensive invasive the hospital. The on-call service must reach ence was not regarded as essential on
haemodynamic monitoring (PiCCO, the patient within 5 min. The unit physicians an IMC [7–9]. However, it is indis-
pulmonary artery or right atrial (including the on-call service) must know the putable that there are numerous situa-
patients. (1C).
catheter or similar) or cranial pressure tions when the presence of a physician
It is essential to ensure that a specialist with
measurement [1, 20] knowledge of intensive care can be present is essential [7, 9]. Examples include sit-
4 Patients in status epilepticus [1] on the unit at any time (within 5 min) (1C). uations such as the status of a patient
4 Patients with elevated cranial pressure less than 2 h following extubation, dur-
[20], subarachnoid haemorrhage The 1998 recommendation that respon- ing admission and discharge procedures,
(SAH) with vasospasm [20] sibility for the management of an IMC patients with unstable vital functions and
should be taken by an appointed director large case numbers. Typical serious com-
Transfer/discharge criteria who is board certified in intensive care [1] plications canoccurinparticularlyat-risk
4 If the patient’s condition does not has since been unreservedly confirmed and ill patients on an IMC as a result of
require intensive monitoring and by numerous specialist societies and is acutely deteriorating vital functions or
treatment is possible on an SCU [1] considered to be medically indispens- emergencies. The immediate availabil-
4 If the patient’s condition has deterio- able. As well as organisational respon- ity of a physician who knows the patient
rated to the extent that active organ sibility, the management function also within a maximum of 5 min is now con-
replacement is required or probably comprises, in particular, specialist mon- sidered essential [7, 9]. To ensure this, the
required, transfer should be made itoring, further education and training IMC physician on duty should not per-
to the ICU based on a unit-specific of doctors and nurses on the unit. Mak- form any activities that keep him/her out
protocol [1] ing bedside visits twice daily represents of or away from the IMC even for a short
a minimum requirement for assuming time. S/he must stay on the ward or in the
medical responsibility. Continuous spe- immediate vicinity. The Swiss guidelines
cialist monitoring must also be ensured require that it must be possible to carry
(see below) and should be largely cov- out emergency measures at any time [3].
ered by the director and deputy. In the Certainly, a response time of 5 min ap-
integration model and the parallel mod- pears relatively long for patients known
els, joint management of intensive care to be sick and under medical care. It is
and intermediate care simultaneously is therefore essential that the IMC physi-
desirable and beneficial. There can be cian is also actually continuously present
separate managements for stand-alone on the ward, is immediately close by or
IMCs, but simultaneous management is his/her on-call room is in direct proxim-
also possible, assuming the prerequisites ity to the IMC.
are fulfilled (full-time management of in- Specialist monitoring must be ensured
tensive care, twice daily patient rounds by a physician with at least 1 year’s expe-
on normal working days). rience in intensive care in cases where it
A clearly regulated and appointed cannot be performed by the director or
deputy with comparable competence is deputy (e. g. during on-call times). Con-
required to compensate for absences due tinuous specialist monitoring by a physi-
to official trips, holiday and illness, etc. cian board certified in intensive care is
without loss of quality. In all current considered essential [3, 7].

Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018 39


Leitlinien und Empfehlungen

Table 1 Listing of technical equipment required for monitoring and diagnostic procedures Nursing personnel (number,
Recommen- Comment qualification)
dationa
Electrocardiographic/heart rhythm 1 Ca – Key statement
Non-invasive blood pressure measurement 1 Ca –
A head nurse and a deputy should be
Intra-arterial blood pressure measurement 1 Ca –
appointed for the unit. The head nurse should
Central venous pressure measurement 1 Ca – have specialist training in intensive care and
Temperature 1 Ca – at least 3 years’ working experience on an
ICU. The deputy should have at least specialist
Pulse oximetry 1 Ca –
training in intensive care or intermediate care
Breathing rate measurement 2 Ca – (1C).
Monitoring with connection to a central point 1 Ca – The head nurse should have a clearly defined
daily period specifically identified in the
Blood gas analysis 1 Cs Including lactate, glu-
roster for administrative and organisational
cose, electrolytes
management tasks, during which s/he should
Arrhythmia monitoring 2 Ca – not be involved in any patient care tasks (1C).
FS3 and FS2 The nurse:patient ratio should be at least 1:4.
(cardiac surgery) A higher ratio is required for higher treatment
1 Ca requirements. A minimum of two nurses
ST analysis 2 Ca – should be present in the unit at all times. At
FS3 and FS2 least one nurse with specialist intensive care
(cardiac surgery) training should be present during each shift
1 Ca (1A)a.
At least 20% of nurses in the whole team
Bed scales 2 Cs –
should have training in intensive care. The
Mobile 12-lead ECG 1 Cs – remaining nursing staff should have training
Transport monitor 1 Cs – in intermediate care or have passed the
Bronchoscopy 1 Cs – nursing examination (1C)a.
aCompliance with this key statement should
Ultrasound (including Doppler) 1 Cs – be achieved on at least 95% of shifts.
Transthoracic echocardiography 1 Cs –
Transoesophageal echocardiography FS2 (cardiac Available in the hospital There is no doubt among nursing and
surgery) and
FS3
medical associations that a unit of this
high level of specialisation with severely
Transcranial Doppler, colour duplex ultrasound Only FS4: 1 Cs –
ill patients requiring far more than the
X-ray equipment, mobile 1 Cs –
possibilities of a normal unit requires
Capnometry 1 Cv – a dedicated and competent head nurse.
Electroencephalography and EVOPS FS4: Available in – Severely ill patients on an IMC are usu-
the hospital
ally in transition to an ICU, so head
Strength and type of recommendations defined in . Table 4
a
nurses require a qualification resulting
from further training in intensive care.
A minimum of 3 years of working on an
Special requirements must also be ful- (neurology specialist or in further neuro- ICU is strongly recommended [1]. The
filled for specialised IMCs such as Stroke logical training), on weekdays through- head nurse also requires structured time
Units. The German [6] and Swiss [10] out the day a minimum 12 h presence available in order to fulfil administrative,
regulations cited as an example here have of a physician dealing exclusively with organisational, nursing, medical and in-
comparable validity in other countries patients on the stroke unit (without ad- structing tasks. The medical director and
and throughout Europe [11, 12]. Using ditional tasks). In Switzerland, similar the head nurse must be in constant con-
the regional Stroke Units in Germany as requirements are specified for the man- tact. Therefore, sufficient time must be
an example, management by a neurolog- agement of a stroke unit and the presence allowed in the job planning and duty
ical or medical specialist, the presence of of a neurologist and other specialist dis- roster without duties in patient care [1].
at least two neurological specialists in the ciplines. As a guide, units with 12 beds or more
hospital and the assignment of a physi- are assumed to be a full-time position
cian to the Stroke Unit at all times (whose (without working in patient care).
time for other tasks must not exceed 20% A deputy head nurse is needed for
of his total work time) is required. For times of absence. Their qualifications
transregional Stroke Units, management should be sufficiently high to allow no
must be by a neurology specialist and reduction in quality.
there must be a 24 h medical presence

40 Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018


A ratio of one nurse to four patients IMC nurses [2]. A rotation of nurses Other personnel
(1:4) is required to cover patients that between intensive care and intermediate
meet the admission and transfer criteria care is recommended as highly desirable Key statement
for an IMC. There is evidence of a clear and as an approach to staff qualification
association between nurse:patient ratios and personal development. Additional posts should be made available for
and morbidity and mortality for ICUs, At least one nurse with specialist in- non-patient-related activities (logistics,
ordering systems, patient transport,
where a ratio of less than 1:2 was asso- tensive care training should be present
telephone service/office work) (1A)
ciated with a poorer result. It is highly during each shift. Compliance with this
probable that a similar association also cover should be achieved on at least 95%
exists for IMCs and corresponds with of shifts. For specialised patient groups, Key statement
the experiences of most IMC operators. e. g. on the stroke unit, additional qual- The following personnel functions should be
Generally, the ratio of 1:4 is regarded ifications may be required [3, 6]. available 24 h a day (1A):
as the minimum requirement for IMC Furthermore, at least 20% of nursing 4 Cleaning staff
by a wide variety of medical societies in positions in the team should be covered 4 Specialist personnel (e. g. cardio techni-
cians, respiratory therapists) depending
a large number of countries [5, 8, 15, by nurses with specialist training in in-
on specific diseases, insofar as the relevant
23]. Numerous medical societies con- tensive care. tasks cannot be taken on by nursing staff
sider a nurse:patient ratio of 1:3 to be Specialisttraining inintermediate care
necessary [7, 8, 15, 22, 23], depending is now being recommended by the Ger-
in part on the severity of the disease or man Hospital Association, which may Key statement
the time of day 1:2 [7, 8, 15]. contribute to an increase in specialist
In some models, e. g. Switzerland, competence in nursing. However, this The following personnel functions should be
a flexible nurse:patient ratio is promoted, does not replace a basic component (see available on weekdays at least (1A):
4 Social services
depending on the severity of the dis- above) of nursing competence with spe- 4 Hygiene officer
ease and nursing costs [3]. As a sup- cialist training in intensive care. 4 Clinical pharmacy
plement to the Swiss calculation model, It is recommended that staff positions 4 Psychologist
other calculation systems for patient-de- for mentors for specialist training should 4 Logotherapy/swallowing therapya
pendent nursing staff requirements ac- be budgeted for [9, 22]. The greatest 4 Ergotherapya
4 Unit secretary
cording to patient numbers have been challenge for IMCs in the coming years
4 Support staff (logistics, ordering systems,
suggested [24, 25]. Such highly flexible will be the funding of the next generation etc.)
personnel requirements (changing from nurses and commitment to one’s own
day to day, sometimes hour to hour) are establishment. The following staff functions are desirable
difficult to implement, so it may be as- (2C):
4 Nutritional advice
sumed that, with bed allocation consis- Physiotherapy 4 Care assistant
tent with the above admission criteria,
there is an averagely even distribution of Key statement
a
Required for specific diseases/IMC criteria.
nursing staff, chiefly depending on bed
allocation. However, prior commitments Physiotherapy should be available every day Medical and nursing personnel must
must always be taken into account. (including weekends and public holidays) be supplemented by other professional
(1C).
It has been shown in Great Britain that groups and staff in terms of work sharing,
the nurse:patient ratio was on average 1:3 competence and responsibility, as well as
across the country and worse than 1:4 in Physiotherapy is a key component of the smooth and safe functioning of the unit.
only 16% of IMCs [26]. It was also shown treatment of critically ill patients [1]. At Comprehensive recommendations were
that using a TISS-28 of on average 23 and a minimum, physiotherapy should be made on this by the American College
a nursing dependency score of on average provided on at least 5 out of 7 days [5]. of Critical Care Medicine [1] and are
1.0, cover of at least 1:2 would have been Whether this is actually sufficient is re- equally valid for Germany [9, 22].
required [27]. garded critically, and daily physiotherapy Regular support of the IMC by a clin-
By nurses, one means a fully qual- is considered essential by the majority ical pharmacy, a clinical pharmacologist
ified nurse [3], as a minimum require- of authors [6, 7, 10, 15]. There is evi- or as part of an Antibiotic Stewardship is
ment for care of such severely ill patients. dently no basis in medical argumentation urgently recommended [1]. An investi-
Personnel with lower qualifications are for two or sometimes more days without gation of a before and after comparison
not regarded as sufficiently competent physiotherapy. Integrating physiothera- on a coronary care unit showed that the
to ensure the safety of patients to the pists into the care team may be beneficial drug costs per admission could be sig-
required extent. We recommend using [3]. nificantly lowered from US$ 374.05 to
only nurses with at least 1 year of pro- US$ 233.0 by including a clinical phar-
fessional experience [9]. A specific re- macist. The greatest portion of this saving
quirement profile has been defined for was on sedatives, oral use of antibiotics,

Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018 41


Leitlinien und Empfehlungen

Table 2 Listing of technical equipment required for therapeutic measures, procedures or inter- Monitoring and diagnosis
ventions The equipment given in . Table 1 should
Recommen- Comment be available. Numerous existing recom-
dationa mendations have been taken into account
Oxygen Insufflation 1 Ca – in the present recommendation [3, 5–7,
Resuscitation bag 1 Cv – 9, 15]. An explanation of the recom-
Non-invasive Ventilation equipment 1 Cv or s Number depending on mendation coding can be found in the
organisation, including “Methods” section.
a range of interfaces
High-flow oxygen administration 2 Cs – Treatment
Transport respirator 1 Cs – The equipment given in . Table 2 should
Equipment for inhalation therapy 1 Cv – be available. Numerous existing recom-
Airway suction equipment 1 Cv or a –
mendations have been taken into account
in the present recommendation [3, 5–7,
Equipment for physical respiratory therapy 1 Ca or v –
9, 15]. An explanation of the recommen-
Equipment for enteral nutrition 1 Cv –
dation coding can be found in the in the
Infusion and injection pumps 1 Ca Per bed “Methods” section.
1–2 infusion pumps
3–4 injection pumps
Emergency equipment 1 Cs – Spatial configuration
Defibrillator 1 Cs –
The recommendations for spatial setup
External cardiac pacemaker 1 Cs – and configuration contain some gener-
Cooling/warming procedure for patients 1 Cv Available in hospital ally valid recommendations, and some
Suction device (for chest drainage, etc.) 1 Cv – rules and regulations have been taken
Special beds (e. g. for decubitus prophylaxis or 1 Cv Do not need to be avail- into account that may be specific to
therapy, heavy duty beds) able but must be deliv- Germany (e. g. DIN specifications).
ered promptly The full recommendations on spa-
Mobilisation aids 1 Cs – tial configuration can be seen on the
Strength and type of recommendations defined in . Table 4
a
DIVI homepage (http://www.divi.de/
empfehlungen/imc-entwurf.html).
Table 3 Discription of the level of recomemendation accordung to the criteria by Guayatt et al
[30] Methods
1A Strong recom- High quality evidence, high quality RCTs, Unlimited application to most
mendation very strong data from observational circumstances Advice on methodology was provided
studies, legal situation by Christoph Mosch, Institute of Re-
1B Strong recom- Good evidence, RCTs with limitations, Unlimited application to most search in Surgical Medicine (IFOM) at
mendation strong data from observational studies circumstances Witten/Herdecke University, Ostmer-
1C Strong recom- Weak evidence, observational studies, Could change if better evidence heimer Str. 200, 51069 Cologne, eMail:
mendation case series, expert opinion becomes available christoph.mosch@uni-wh.de.
2A Weak recom- High quality evidence, high quality RCTs, Can depend on circumstances,
mendation very strong data from observational patients, social values
studies
Literature search
2B Weak recom- Good evidence, RCTs with limitations, Can depend on circumstances, The Summary of Abstracts was a system-
mendation strong data from observational studies patients, social values
atic overview of all relevant publications
2C Weak recom- Weak evidence, observational studies, Very weak recommendation,
(01 January 1990 up to 27 June 2014) that
mendation case series, expert opinion other alternatives could be
equally beneficial provide information on the structural/
organisational/structural requirements
and staff/technical equipment for pa-
improved antibiotic selection, a consid- Technical equipment tient care on IMCs, i. e. transition wards
eration of interactions and the avoidance between ICU and follow-up treatment
of double orders [28, 29]. Key statement on an SCU. The literature search was
repeated with the same criteria for the
The technical equipment in the following two period from 28 June 2014 to 22 Novem-
tables for should be available for monitoring/
diagnosis and treatment.
ber 2015. Recommendations were also
sought from German, European and

42 Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018


Table 4 Type, strengthandscope ofappli- Results Acknowledgements. We would like to thank Dr.
cation of the recommendations on technical After carrying out the systematic search U. Dennler from the Division Manager Medical Con-
equipment trols of Jena University Hospital for reviewing the
on 27 May 2014, a total of 911 potentially manuscript and his valuable input.
1C Urgently required basic structure and relevant publications were identified (af-
basic equipment Conflict of interest. K.R. Steinmeyer-Bauer: At the
ter eliminating duplicates). In the title/
2C Strongly recommended structure and time of joining the authors in 2014 to April 2016,
abstract screening, a total of 73 publica- Dr. Steinmeyer-Bauer was visiting researcher at
equipment
tions were included and checked in the the Department of Anaesthesiology, focussing on
FS Specifically required structure and full text. A total of 23 full texts were surgical intensive care medicine CCM/CVK, Char-
equipment (5 specialities) ité—Universitätsmedizin Berlin. At the same time, he
used as the basis for evidence (see flow was working, and still works, for VAMED Management
FS1 Anaesthesia
chart). For the supplementary period of and Service GmbH Deutschland. The unanimous as-
FS2 Surgery (general and visceral surgery, the second research, three publications sessment of the authors was that there was no conflict
cardiac surgery, thoracic surgery, of interest resulting from his activity that had any in-
orthopaedics and trauma surgery,
were checked in the full text, of which fluence on the declared recommendations. E. Herting
burns medicine, transplant surgery) one was used as the basis for evidence. states that there are no conflicts of interest related to
this publication. He reports grants and personal fees
FS3 Internal medicine from Chiesi and Dräger, outside the submitted work.
FS4 Neuromedicine (neurology, neuro- Consensus finding G. Marx reports grants and personal fees from BBraun
surgery) Melsungen GmbH, grants and personal fees from
A first draft was compiled by one of the Adrenomed, grants and personal fees from Biotest.
FS5 Paediatric and adolescent medicine G. Marx is DIVI and DGAI Board member and Coor-
including neonatology authors (C. W.) based on the identified dinator of AWMF S3 Guideline on volume therapy.
a Permanently available at all beds sources. This was discussed and con- C. Waydhas, S. Kluge, A. Markewitz, E. Muhl, T. Nicolai,
sented in two Delphi rounds, one con- K. Notz, V. Parvu, M. Quintel, E. Rickels, D. Schneider,
v Available on the unit and promptly or G. Sybrecht and T. Welte declare that they have no
immediately deployable at all beds sensus conference (16 June 2016) and a fi- competing interests.
s At least one device/article available nal Delphi round on 19 February 2017.
on the unit ready for use The authors comprised DIVI representa-
tives from five DIVI specialities (anaes- References
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44 Medizinische Klinik - Intensivmedizin und Notfallmedizin 1 · 2018

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