NAME OF DOSAGE, MECHANISM OF INDICATIONS / CONTRAINDICAT SIDE EFFECTS / NURSING

DRUG FREQUENC ACTION PURPOSE IONS ADVERSE EFFECTS RESPONSIBILITIES

Y, ROUTE
Generic Name: Dosage: Furosemide promotes Furosemide is  History of GI: ASSESSMENT:
Furosemide 20mg diuresis by blocking indicated for the hypersensitiv - Nausea - Monitor patient
tubular reabsorption of treatment of edema ity to - Vomiting medical history
Brand Name: Route: sodium and chloride in associated with furosemide - Anorexia for any conditions
Lasix IV the proximal and distal congestive heart or - Diarrhea contraindicated
tubules, as well as in the failure, cirrhosis of sulfonamides - Constipation for use of
Classification: Frequency: thick ascending loop of the liver, and renal  Increasing - Abdominal furosemide.
Diuretics Every 8 hours Henle. This diuretic effect disease, including oliguria, cramping - Monitor patient
is achieved through the the nephrotic anuria, fluid - Pancreatitis intake & output
competitive inhibition of syndrome, in adults and CV: constantly.
sodium-potassium- and pediatric electrolyte - Hypotension - Monitor vital
chloride cotransporters patients. depletion CNS: signs before &
expressed along these states. - Headache after
tubules in the nephron,  Hepatic - Vertigo administration.
preventing the transport coma - Dizziness - Assess for allergy
of sodium ions from the - Blurred Vision to sulfonamides.
lumenal side into the EENT: - Assess patient for
basolateral side for - Hearing loss skin rash.
reabsorption.  - Tinnitus - Check patient’s
GU: labs ang
- Increase in BUN electrolytes levels
- Excessive periodically
urination throughout the
- Nephrocalcinosis course of
DERM: treatment.
- Pruritus
- Urticaria IMPLEMENTATION:
- Vasculitis  If administering
- Rash twice daily, give
- Photosensitive last dose no later
HEMA: than 5pm to
- Anemia minimize
- Leukopenia disruption of
- Aplastic Anemia sleep cycle.
- Thrombocytopeni  IV push:
a Administer
undiluted
Concentration:
10mg/ml
 Rate: Administer
at a maximum
rate of
0.5-1mg/kg/min
(for doses
<120mg) with
infusion not
exceeding 10
min.

PATIENT
EDUCATION:
- Encourage patient
to have an intake
of potassium rich
food to help
replace potassium
loss.
- Instruct patient to
monitor for signs
of hypokalemia
and immediately
notify physician
or nurse for
muscle
weaknesses.
- Instruct caregiver
to take
medication as
directed. Take
 missed doses as
soon as possible;
do not double
doses.
- Instruct patient to
avoid sudden
consumption of
large amount of
fluids.
- Caution caregiver
or family to
change patient’s
position slowly to
minimize
orthostatic
hypotension
- Advise family to
contact health
care professionals
immediately if
rash, muscle
weakness,
cramps, nausea,
dizziness,
numbness, or
tingling of
extremities
occurs.
- Emphasize the
importance of
routine follow-up
examinations.
Angelo Signor, Alfredo Guerrato, Giovanni Signor, "Process for the preparation of furosemide." U.S. Patent US5739361, issued June, 1971.
Gil Wayne, BSN, R.N. (Sept. 8, 2020) https://nurseslabs.com/excess-fluid-volume/
WWW.KIDNEY.ORG/CONTENT/NEPHROTIC-SYNDROME-GUIDE-EDUCATE-YOUR-PATIENTS

Orth SR, Ritz E. The nephrotic syndrome. N Engl J Med 1998; 338:1202.