oe Introduction TO microbiology! Microbial contro! eee geri eels oc 6 Sie ae Characteristics of endotoxins ont, A high concentration in quid medium 1D. does not produce tev B —_foundonlyinboth gram(+) and gram(-)bacteia. E.—none Converted to toxoid virulence factors, EXCEPT: © Fand M protein D. —_noexception ound in which mecroorganism?, ©. L. pneumophitia DN gononhea briae of bacteria (eg. Streptococcus pyogenes) which causes adherence to buccal epiptial cells, cfbronectin ‘ Done is © found only in gram (t) organism D. none andebain eyecare all forms of microbial fe F plduce fever ©. sterilization exebexin i damage to DNA, EXCEPT. eee ©" UWiight :, D. —_noexception ne bere Fin Tiquia® medion ‘A Used forinanimate objects Peptidy! transferase MPs 8 © Amino Acyl tRNA 5 e 23s RNA ; s oe Clindamycin 3c HH ¢oU loo . LIVOC 0. ELISA 65, Medium ufed forthe culture of Bordetella pertuss: ‘A. Lowenstein Jensen medium 1B. Looter’s medium ©. Mac Conkey medium D. Bordet -Gengou agar 66. Reganting the spasmodic siage of pertussis ’A. the bronchial epthelium is norma in this stage x B.-A egins with conyza, sneezing and cough ©. ‘tis characterized by a violent, repetitive type of cough that forces the ‘ait out of the lungs and is followed by a sudden inspiratory whoop D. itlastforless than a week 67. Bordetella pertussis is corectly described by which of the folowing statements? 'A. tis commonly transferred to humans from infected animals B. produces several determinants of pathogenicity CC it commonly colonizes the gastrointestinal tract 1D. Weommonly causes disease in children older than 5 years 68. The usual couse of food poisoning in re-heated rice is 7 Bacillus cereus chy yet ru. B. Clostridium dificile Escherichia. Col . Clostridium botulinum (69. A 25 year ok! woman developed nausea and vomiting after an eating binge in Chinatown; investigation showed that ‘he offending organism is a gram positive rod and this is > © "A Conmebacterium diptthena Bacillus cereus ©. Clostridium totani D. Bacillus anthracis 70. Which & the folowing statements isnot tue of Bacitus cereus? "A. The shod incubation syndrom i characterized by severe nausea and vomiting and is frequently mistaken for staphylococcal food poisoning Chloramphenicol isthe antibiotic of choice for the short-term incubation syndrome C._causes@ cinical syndrome that has a short period of incubation of about hours. 1D. The second syndrome it causes is characterized by abdominal cramping and diarthea and takes about 8-16 hours to appear ee oe see eo om 72. Which isthe best statement concerning anthrax jn humans: ‘A. cudaneous anthrax occurs most on the feet BZ attacks are extremely common the organism or spores may be inhaled or ingested . tis acquired exclusively by accidental cutaneous inoculation 73. Which i the best statement regarding ‘A Isa smal straight gTOws under anaerobic conditions 8. Causes anthracosis which is transmitted exclusively by inhalation C. Forms spores that are extremely heat-s ensitive © £auses Woolsorter's disease and is spread by contaminated it‘wool, horse hair and hides cereus with heat stale enteroxin rooster Rgeson reste * A. 30 ihinutes to 1 hour B. B16 hours — LY aenen GRE NOUE EAN ante ty Rud NOUS 75. Which of the folowing bordetela is associated with respiratory diseases {cats and swine but can cause also. broncho -pulmonary disease among lmmunocompromised humans. AB sis B.B.nowi cB epticus .B. pulmonicus, 78. Which ofthe folowing is /are characteristics of bordetella pertussis ? ‘A. Fasticious aerobes, incubated for 3-7 days A capsulated “C. both D. neither 17. The complex media used for B. pertussis contains charcoal, blood or alburmn ‘A. To ounteract toxic compound in the agar B._As growth factor ©. Both D. neither 72. Bored ptunis surved fo long parts cutie the body Ise 79, The virulent starn of B. pertussis produces hemolysis in blood agar A True B False £80, The symptoms of whooping coughis caused by + ‘A._The aftachment and growth of the organisms on elated ces * B. Etfects of secreted exotoxins ©, Both D. neither » ‘Match the toxins of Bordetella pertussis with the action/functions Taxing: A. Pertussis Toxin ( Pertussigen) E, Filamentous cpmageres are F_ Lipopolysaccharide (LPS) F 81. generate complement activation products, LPS D_ 82 very strong vaso-constrictor and causes ischemia hest=lehile Toxin © 83, in higher concentrations, it causes ciliated epithelial cell extrusion ‘and destruction tracheal save ‘A. 84, causes T cell lymphocytosis _prertuyis fern ‘ 'B 86,_ catalyzes the conversion of ATP t0 CAMP. danyinCe eystase Teas 87 Antibodies against these molecules are protective, probably bacterial attachment. agylunsgens ae 88, Which is/are tre of Bacillus anthracis ? ‘A. Aerobic, spore-foffning in soil and in the blood “ae 3 Spores remain viable in sol for decades Dineither 89, canicueharc iesAoianeous route Transmitted by insect vector Ingestion of contaminated meat : \ A vonatavon ot spores q 40. Which are te ofthe virulence factors of 8 antracis? | ‘A Was two plasmid coded heat stable exotoxin 4 8. Antibodies to the PA ( protective antigen ) prevents the binding ‘of PA and stop the entry of EF andLF C. Both D. neither 81, The capsule of anthracis isnot a good immunogen, though itis ant-phagocytic AThie B False 82. Which othe tre ragments othe exotoxin of 8. antracis wil act as an sae pan (er) ~ B. Lethal Factor (LF) ©. Protective Antigen (PA). D. Nene ofthe choices {nich toxin of actus corus wil activate the adenylate cya enxymes? A ©. Both toxin 1D. neither ‘94 isolation ofthe organism from the stoots of patients isnot sufficient o make a diagnosis ofB. Cereus poisoning because sore haelthy adults may carry them transiently in their GIT ATrue B False 195. 8. coreus gastroenteritis is generally a benign, seltimited illness, antimicrobial are of no value in management ‘A True B False 196. The shor-incubation form of B. cereus food poisoning is associated with rice dishes that have been cooked and then ‘held at cold temperatures for several hours. A. True B. False 197, A human gnd animal vaccines are available for antrax A B False 98. Alforms of antrax are significant in biological warfare ; ATue 8. False | 99. Characteristics of ‘A. Formation of vesicle with blue- green edema id B. Black eschar called malignat pustules D. neither ‘caused by inhalation of spores of B.anthracs as well from person to person~© Trmnenmman_fcitia Chianti Mycopleams Oer pathogens Baca 24 “eevection fo Vsiony 1 Memntceeenens of Chlamyeiatrachomats 1 related 19% apes Facute body (RS) © caval 5. Sementary body 2 An ctaganitrcedia organism that requires hot cel ATP f parasites of ving cells 1 cin ee ae eer serena ere ge ane eee yess ce convo EXCEPT 2 AL Typhus-e 1B Iymphogranuioma vere 6. Epsdemologicaly, Chlamydia trachomats infections canbe dided into al the flow ‘A. middle ear infection in young children a trachoma infection 3 ‘ransimited genta infection in aus ¥ D. “perinatal conjunctivtis 7. An 18 year did commercial sex worker was admitted for severe abdominal pain wich ‘necotpanyes, rere faver nd anorena. On examination mass nthe let adnexa Maree on sbotess and a agnosis of pee inarmatory disease was gven O'R clam trachomatis 8 Moraxolia ‘© Mycoplasma prewmonae D Steptopeoccus agalactiae wich tow i fedora contig gyeagen? aera reckaate Bch ts C. Chlamydia urealyticum D. AandC only © Lmyearcttenle conse the OPO cnc for ewan and fiat unaton She had been eee {Boyer ee ore cota roommates abot er condton forse hints is connects Pe! Scenes awa Se sce abot aveck ope, Tis happened Decuse sel faered wh he eto she gt ne oat, eanvre croton claaaterane rote up win KCM Tomae he sry shor she fet et epaal cals ‘end tre gor ‘gutty_AUunnalyis was done and it showed 10-20 cels HPF. Ri ‘organisms _ The doctor suspected NSU which could be due to Chlamydia trachomatis the vine sedment not show any ‘She had taken Peniolin and ths probably was the reason why no organisms were found in the unne? reason why no organisms were found inthe sediment was because she had taken Pe! B. No Was LJ right in assuming thatthe A Yes 410. . Which of the flowing best describes C trachomatis? "A. Wid not stan wth te gram staining because fthas no peptidoglycan layer itis an obligate intracellular parasite (ntecions ofthe col wil result in cel lysis allofthe above E Only Aand C are correctA mea of specimens seraoge deter amyaia ©, all ofthe above 12 Which serotypes of Chlamydia trachomatis are associated with NSU and reo nections NU 8 DL CAD 0.0K 13. Which ofthe flowing sare com (@ Rinthe ony species of fect of Chlamydia trachomatis 5% chiamyéia, which produces glycogen inctsion body ay/me tte cyce of ©. trachomatis inthe cell is about two days 6 The reeatate body isthe one which spread from cel!to ell ©. Abare conect 2. Only A and B are correct 14. Which is Pa common cause of camamunity ~acquived preumonia? A yao preuTona® Y aiypcel Chara pneumoniae 1B Ureaplasma urelyticum 5 ‘Greptoccoccus preumonies 15. Which ofthe folowing Chlamydia is/are associated wth Alzneimer’s disease, ‘A Chlamydia trachomatis 'D. C and D only 18 Chlamydia psitac G-Chlamydia pneumoniae 16. Characteristics of C. pitact 'A can also be passed inthe e995 6; batn neither (B readiy transmissible to humans “1, Resene . pates &xcert)) . humans yet Pe B. cattle © ngayon te O oe 418. In the colection of specimens of cases suspected to be caused by cataine along ire wwe? , esa ich he ol eofect specimen om the vagina \E Avoid contact with antiseptics solution: ;, creams and lubricants eters paced sane son D Ale cored 419. Which ofthe folowing statements about th ‘A. Tetracycline or erythromycin significa from the respiratory tract by therapy jasma has been shown by culture to be present inthe RT fe treatment of mycoplasma caused pneumonia is/are correct ? rly reduces duration of signs and symptoms and hastens the resolution of \ che st fn findings 8 Mycoplasma is not eradicated C. Four months after treatment, mycopl D. Allare correct 20. Which mjcoplasma wil produce clones in 3 weeks ? ‘A Mycoplasma horins © Ureapiasma urealyticum D Al choices B, Mycoplasma pneumoniae mice y deer a tats Brea ore (are) deer C ti E Aand B only F. Dand aonly B. house rodents Q field mice 2 mange ott et CC. Fusospirochetosis D yawseis eee nega S o sone epson et ct ae mate ion 247 ete cams 28 colar ery ot mone 28.4, Wie Ah aerate TUE ad sateen FALSE AZ Themen dolor gee ceo me cnet 27 F 82 hap enn pment 8 F020 Caonted cna ae sandy Wight santormane mem vate pieigtmarcage +7 asi, Since by meal he ptt st ‘so nae oro sete 17 832 me re ce pt x nce 7 A31 manped yee cosa use when mgr, 1 M® Mite cee apna cle n tne reap 7 nv coeanbusesmane = congcabon yoann secon cmon ns ere sdeean may rm onewtt emus Oy tt i ors one nm nedac pcan rane 0 cnr ar) "tne maecpogenes Cm chen 3 Watney” 0. Pte mae a ng so : ro 6 Cate boras 90 mason 2 Rewan 38 wa ee cae cl pres A screaa 6 Poconos ¢agjonate 0 lone © eva to ow nae re 5 tomy sue C4 any bd sored aC dahcostgn wih oat, odteah te Bsese ar en cada wih Se prevence frets oe ae «wg otf pment "ce ee en Ff = a er) 2 Voc wie 2 i Tage © bom ‘3 Wtereanaterngetan ofconararates water. her Be. gastrointestinal tact 6 acs, ony of mov0oy 8 ‘Respratory act 44. wich ofthe folowing iat true Df Listeria monoeytoge ‘A. gram negative Bactorium ‘utbreaks can be due to ingestion of unpasteurized rik C tnawnto cause meningitis ‘Duncommoniy diagnosed infection 45. Which sate ofS. monliformis? 'R. Gram nagative pleomorphny bacilus D Allofthe choices 8. Normalmnabiant of squires, weasels andirats & Only 2 are corect CC Facitatve anaerabe 46. Rot be fever is caused by Y KP pseadomallet 1B Streptobcillus moniliformis (C. Staph aureus . Yersinia pestis 47. Gardnareta vaginas s one ofthe organisms involved in bacterial vaginosis Which one "afte following crtera is LEAST effective for diagnosis of vaginosis? — = ‘A. Culture of G. vaginalis 2 Thin, ky vaginal discharge B Vaginalpl > 45 & Presence of cue cals “Alchy srell for the patient Fas 48( Qoncyan bodied e associated with v1ev 1B. Calymmatobacterium granuiomsts C Memophius ducrey D. Chiamyaia trachomatis, 49. Wich statements regarding Treponema palium $A Despite the therapeutic use of peniclin fr many years, no penilin resistant strains of T_palidum have been isolated 18. Specimen cuftures on blood agar plates reveal alpha hemolytic colonies. . Since the tension of primary syphilis ae primanly due to an ”" tmmuane response against the organism, the tension typically few T pagum cells, D. iia spa shaped rod hat sppears gram postive in gram staned sere 50. Which tthe folowing tests is used in screening for syphilis: rapid plasma Reagan test FPR Ter {8 fuorescent treponemal antibody absorption test a CC. Treponema palidum hem agglutination test 1D. Treponema paidum immobilzation test 51. Avinsis defined as ‘A. the smallest living particle obligatory intracellular C. capable of causing diseases all ofthe above '52. One ofthe folowing is Got.a characteristic ofa virus ‘A. itpasses through bacterial fiters 6. itlacks the necessary enzymes for metabolism C._nonets susceptible to antibiotics nat destroyed by heat 1 ‘53. Most viruses have all the following componentslexcepy ‘A nucleocapsid B. envelope C. vinon D. capsomers '54, Which ofthe folowing is (are) common parasitic microorganisms of the al vac ? eaplasma urelyicum © Mycoplasma pneumonia 8. Mycoplasma hogminis D Aand B only 55. Val capsomers ace accumulations of ‘A. nudeocapsids Bs eee G/identical protein blocks Dallofthe choicesRian ie 1 prcomane © Sapna re 0 ven er got cand ; 01 wea pcaagatas wages Theccccrvornemencass ‘2Reaatony 0s ost plese oe nee 8 hams mono paae 7. atom rtd went ee an, Sens cians wt SF wen ep "tt rin sow pong ene Noon Sat geo or £8 Ciara ere ures attcum oo ee Cais flupnbmenas =a samen comes no © Re G roc wets. OMA inset ameniying__ ie don a ay Se 5 Capi 3 Socre. 6 ncaa once soa 6 Tg tec otc none a e? 5 Mnatbeteam tte cate bone ne copes inanom ne cess os uaassgemeas O ammogyconde: (cephalosporin renee etn ds Ana Se ioe moneys ae (Blood agar medium ieee cringe rena psn tna eato tm bactrurn a more severe then Bat coused by thar bectea (ee deccnbed we primary atypical preumonia 1 ‘Ujcapaunaponremae ox rae an 50% ft cases poemona 71 We etacton mayest TR foaiaon sary wise 0. allot chesStare te host RNA podymerace to transcribe the () RNA 0 (2) RNA 8 the wal ONA integrates Both are correct Oe Nesher toe fs corect 4 Mycoplasma irs hom chia that myeopiase "A. are alresistart pens Cane propagated on col tee mesia 175. ne rience of make vss "A. the spies are inserted nto the host cel membrane cat disrupt ‘Bat are correct Nether one i comect 78. Thefotowig ae wpochetes, which one isthe etiologic agent or rflapsing_ fever Av Borrelia recurrentis: 8. Treponema palidum 5 Leptospira interrogans 0. Borreha burgdorten . 7. invral pathogenesis the nature at the disease wil depend on al of the tatouing ent ‘A thetype of wus 'D. none ofthe chelces B target organ E AandC only © genetic make-up of the host $0. The CPE or catyuryin rat nection may res 1 all ofthe choices B. aisrupbon of cel structures ‘Enone ofthe choices + ©. transformation of cells 78. Which of thrfolowing antimicrobials can be used for bacterial vaginosis? 4 A metronidazole Peniciin vancomycin © suite 80, Which othe folowing best descnbes the“ dv col "A. a PMN which wil show phagecytos6d organisms on gram staring and in wet mount 8, Squanes ep cas hsv Inden wt ram negative cranes comet Neither A nor B is correct 11, Which fhe ening rere fs? ‘causing syphilis is a gram indeterminate organism ‘A organism B the etiologic agent of syphilis can enter breaks inthe skin and mucosa {the ete agent of sypils can als eter intact skin and mucosa 4 pamary syphilis is most infectious D. all of the above are correct E Only A Band D are correct 4 a2. Donovan bodes is associated with, a alah © __Calymmatobacterium granulomatis, 8. Hemophilus ducreyi 1D. Chlamydia trachomatis < £83, The following are serologic tests used in the diagnosis of syphilis. Which is NOT specific for Treponema palidum? ‘A. mecrohemagglutination assay for T.palidum Sees eTreponena pan’ B._ Rapid plasma reagin ( RPR) CC. T.palidum hemagglutination test 1D, Fluorescent treponemal antibody absorptionAi yoat wi female GRO by occupa ‘man show wktse parasites. You cay +x Yranomcnas apne 6 Cramyaa Two ade tested ponte for VORLIRPR which te A 8 FTAABS test ©. TPHA © esa (6, Sane eryupelas i caused by, R'E rhusopathiae * 6 Spiitum moar © S.monaormis 0 Pasudomonas 7, Successhy vested syphis shows decreasing ter of artbodies nts test 1 VOR 1B TFAABS © complement tation © THA 188, Rechts ifectans are transited by "A Mosquto grass insect +) © teas 0” potted water 80, Members of thé genus Rickettsia are grom negative bacteria that i derive most of their energy for oxidation of htamate 2. Sonat mutipiyin endothelial calls of smal! bood vessels ‘ore fective nvacelutarparastes D. can be classified as energy parasites 50. (ese etopod vec ot J Eadimcyphas = D-bbonepleque © Fatcopetan pros Muone ps 6. jocky mountain spotted fever 91, The only rickettsial disease transmitted through fortes “A Ricketts prowazekii (B.)coxciela burneti © Rickettsiae aka ‘D™ Rikettsiae quintana 42. Vows wih characteristic skin lesion is « non-syphilie reponematosis and sy the tiologic organism is se ‘A Borla burgdorte “Treponema pertenue © Leptospira interrogans Treponema carateum ats favour apostate is waned by atropods and can cause * Tymeiene and —reareng fee! : ‘3 epee pene . Treponea cartoon D. Leptoepre . Borrelia severe headaches , muscle pain and conjunctival suftuson. He gave a history of including blood cuttue on Fletcher's semssokd media. This "a, “Leptospira interrogans D_ Treponema palicum 5 Borsa scuents is #sprochete ands the causave agent of selaping fever Which ofthe folowing statements 'sNOT true ofthis disease? “A. ee wih Treponeme paid, Borela passes thu the placenta and congental infection occurs The drug of choice for this disease is acyclovir Bnet i pray based on the demonstration ofthe orgaiam wih nine or acd dyes S Diagnoses e characterized by chil, fever, anusea and voriing, myalgs, atralgia and protopnoh2 196. Which is corect of Q fever? ) ‘A Caused by met © Can cause abortion in animals Transmitted by inhalation © Only &c are correct E. all are correct, 197. Lab Diagnosis of leptospirosis during the frst 2 weeks is done by testing ‘A. Blood Both 8 Unne 1 Netheryea WetA WRES NECACE Pete HERPES Weast » AR eHIE aR PSSA RAR Rak naronmaioute shout bo Nop aingle rooms to prevent transmission 19 o1ner \ eet 4% _weaetns entvonon a the aamnate teatmant of choke far legionellosis © Cage a pony mate ne cgannm spread wa aerosols - Aaumere so eas we neaey egrets sakers axe mare Huacepine to lagionelonl than are young acts who ave ont eave ame Waa ane athe Rung tapout regarding Legionella ry ‘ ‘A roam bo trkatest By growth can aga a the aboratory Mt Tee an negate inteaceliar paaaite 4 & Karem conte of pmeunona Because t's pa ot . Tee aon tv oF he ovat ANA . ‘ © Wo vagatzed o Rear repwarest gram stains of oneal specimens faaman to nana banarnsrn & feaponaible For epitene outbreaks,pe: poy @ Mer cnn, thu, ra thane ase fomciin,Paremyaeranen (FA ree" Viruses, Reovinises, and Epidemic Acute (Castoenterits viruses Whe ofthe folowing is a DNA vrs? A hepa Aus B togawns 2. dhe targst and most complex ofa vruses are wx poxwruses C._herpesvruses B eowuses D mabdoveus C. Papitioma Virus Benin 3. Conc tonsits aris is caused by ‘A hapes simpexvieusC. rhinovirus 8 cytemegalovitus .D. adenovirus used to diagnose ©. candida A, leptospirosis Bhorpes Hs malar 3. is nonucteoss's caused by. seo, Oe Ripe enters”, Epsen— Barve ig Jo” 8 hao i conn C. brucellosis D tularemia Fetal abnommaites including microcephaly and mental retardation are ‘een in nfecbon wth 'A herpes simplex virus etomegalovirus: Human papa vrs associ wh his ranane C Epstein-Barr vius 'D adenovius See asophanyedl carcnomaG< Cervical carcinoma 8 Buntympnoma ©. Kaposis srcoma an dplenomegaly.wth hematologic fridings of numerous atypical lymphocytes naeropiie anibodes, The most probable diagnosis jsmononucleosis..brucelosis os D. tularemia 10” nfectous mononyceosis wth a NEGATIVE heterogile antibody testis caused by ‘omega B. adenowrus netesomaryagealcarenoma” C.csbicalcarcinama ome [cKaposis sarcoma? 12. Common sirrent csease produced by herpesvirus type 1s: © Gental EV 2 1D encephaitis 9 viuses contains structurally essential pid? C. papilomavirus © pox vius 14, Latency in adenoid tissues are characteristic of A ispes simplex virus ©. cytomegalovirus B Epsten-Barr virus adenovirus. 15. Epstein infects B lymphocytes 8 le nected cos © spect localizes infection oes nk co antibody formation 16 fe peak incidence of the following is NOT in chien:amma Brame g.shingies, 0 Tube A> vaanan peri virus 6 and 7 cause! shingles © microceptaly Dicroseola intanium fecgous mononucleosis Wich fe atoning s most involved 9 MA doaal unk nerve T00t8 B fast neve herpes zoster? © perineal area 1D lower extremes Komappecean ure. onne peste ona EET = saan OMA ae rags aso 24. Adenoviny inteons primarily involve the: ©. genta tract rei respiratory act é Br gesvortestnal act wary tact ft ‘Match Column A with column B column Aj Viruses). The letters may be used more than once A Sonatipox virus 7 8 Adenovruses « ©. Voncela- zoster vrus Haman Herpes simplex tend 2+ E_Oytonfegatovirus F Sear vis 7 & Raman peploma wus iypes 16 and 18° Hi Motuscim contagiosom « cotuma 8 { symptomsidiseases /linical findings) 21 produces the bigest intranuciear inclusion De omy ‘Bucs eng tumours beng the pox gOUP of Kronuscurn contagiasoin soa. Rosoctated wih cancer ofthe cervix iF 18 18 eng press aay Produces Pfecton which affects dermatone supplied by the of je VV SBUBe4 are mare onthe face and trunk (centripetal) V2 E es & bm 6% C28 Bat camessregeye dung suremer Atnoy8? F 28. “hosang aseose ES eae es testinal infections 3° Ax. ea F D can cause respiratory and gastoi ca essed by this has been eliineted =! 7°” Burks Lymphoma BV 32. heterophle antibodies EBV 5, Nett genta lesions may be symetomatic or asymptomatic. 15 10 statement is FALSE17 Patt epi a kat ny a) Sar a Sepang. "Cnc tees 0 Ate pcan teas se 2 erent 6 re Sameceeae 0 wage rersoan Trans oe eae tne eae St hep ot are 3 pet's nan cet iecaos nannov Praca oo eanecr ary ees _ 2 Sinadony 52 Ape hn nrg serge mater HB) eB) A Teciph mea soap masks wa you regio eam e Ate 4 RTgeaeee 8 Mannie C Hehe Anite 53 Too pat meres “x Tanner nes 8 pepe micns nace . Cambe on to orage or erica 5 Mipatecse nsieas saree orator 4 Apeon Hs aagen poste How agen negae “Cas pao intr Retest POR emo race Epic 0 pas ach the membered tema wth he eared onesSan eye “ea roto cote setae of ues ves parte 1 Romees Ss Sol an nutes coe. parce rng agent ¢ Ragusa are coninous won of nw stan 70 Tet “nice nfecton eet cera ops mon se See a Be © Mom ogene ange 5 necesthe heathen spent ork piheeen fe paces 3 6 is Rims a Ser oben tarae eee ci Rag ea ec a Teta wot ama ns anes Satara Sergeant moran 9 copeeeiierass relarcenics "Sec Sas gales re a“ eto antoe 5, Won reow cones gatoutrts ots nd young chien? "Pom “Bhssanaun C Comooke Bye Oris, Wer ons tasbeen mpc se case of gotta st? Maan Guns "orwak res» © coerinD.hepens 7 Tatton teers so asus are cate, EACEPT. “tens mapr can of neonatal deren 8 Ea eeassang haps pte! nonates sgn © Went nly asa singe strain 5 hoa neu tne Have maternal acute potecveaniboies 68 Connie "Rg we re sua ct ctr nes 8 gowprotasy 0c 6 fre tants ere reuanty than ats © ae te common cols 9 Retna “Rhave a double capsid structure 1 sige anced De gence ana et IA poymesaae or mRNA nes speadbymoseutoes 90 Ret iat vy ado ‘A mapantvnstamator1 singe stranded RNA viruses nonetweloped . Sssembled the nucleus of host cells © doselyreated to reovruses ‘notype ci sytomearsosted wah lav ineto " Waeepaanacynsome ‘ae Eunausea, asin and diarrhea of infants sane nate 63, Rotawuses der rom poiovruses in that rotavituses: ‘A nfed va the fecal-ora route 8 lack an envelope * Co nat contain any enzymes D.can undergo genetic reassortment i 94. Rotvnuses cn be dstingushed from other members ofthe reovuses Ay spear 8 intnattay ect humans ony | inthat they replicate completely inthe nuceus © minty havea sepmented genome 5, The stools rotavirus infection are described as ‘A body 8 fatty C. watery D. necrotic. | 96, The dagnosis ofa rotavirus infection is cinched by 'A solely on cinical presentation (Browse electron microscopy of stool Gelperease in antibody titer 1 epidemiiogic grounds if there is ongoing epidemic fda anon tices ura? eof ebony drug OEE iat Setar on. camo ST waposb onset inet ete pach Pier. oiece ‘DE protein 00" Te ga trac 0 SRS nnn, CERT A high fever ex pe rnees C. elevated lymphocyte count D inereased iver enzymes 100. Managemen of SARS cases include 7 alaton and quarantine B bed cures © chest raographs D.allof the above stop! (duplicated /) RNA viruses; GIT infections,Rabies and arbovirues , Rubella, Retroviruses,etc, prions) Write A ifthe statement is TRUE and B if the Statement is false B 1. Animal coronaviruses replicate rapidly in high yield in human. B2_ Rotavirus causes gastroenteritis in older children, ‘A 3 Norwalk a common cause of gastroenteritis in adultsa Seeeges ence tor wi wtections include tissue tropism fe the bain. mea Ye - 24 40-87 ‘A. Pneumocystis pneuihona FO A\ 42,94 © Candas choose the Bost answer ne Kaposi sarcoma A an adenovis 8. hepatitis ws At othe fowng categories petorosewual IV tug users enualy active homosexual females eterosesval sexual partners of persons with AIDS " "Sealy active homosexual males Infants bam to mathers infected by HIV © anerpervirus . potowns ‘of people are considered at high risk for HIV infection EXCEPT moop> coe ved platy ct wht toad cote wean inpariant ps ofa pulnageness. Which atthe felon fe least Mey 1930 ns? A. Cytrnegalovieus c. HV (Egat Bar vires D. rabies virus 11. The termi isan acronym for . pronty oncologic system ‘A por ongoing infection — 8 proteinaceous infectious agents 12 Unike ther ving axganisms, prions contain only "A protein EB mucieic acd C.lipid D.carbohydrates B'present in nature 13. Prions repeat by ‘A sexual reproducton inary fission 8 conjugation . host protein conversion 14 Prons have sar charaéteristics to viruses, EXCEPT "A obagate intracellular paraste {8 unusual resistance to some inactivating agents © no-apparatus for energy generation emai Merable agensts ¥ 45. Agent that CAN inactivate prions: > A.sodium hydroxide formaldehyde ethanol BWV and onzing radiation 16. Poon diseases are confined to which body system? ‘A respiratry 8 gentourinary C. central nervous D. musculoskeletal 17. The type ofinfection caused by prions: A.aborive B.latent C.cytocidal D. slow 18 The folowing are characteristic pathologic findings in prion infections, EXCEPT: C. granulomatous inflammation A amon fas 8 nouronalloss. astroglial proliferation 19 Prion diseases may be D all of the choices A acquired B inherited —C. sporadic 20, The best example of drect human to human transmission of pron saease: ru ©. scrapie 8 fatal famial insomnia D. Jakob-Creutzfeldt disease 21 The sens of mmunologe response means hat ths dagnoste moda ‘15 useless for pron disease = 2 tsAA biopsy Define treatment fr prion disease "A vacoinabon 8 imereron D-none 23, Re-emergence of known viral diseates occurs due tothe following, EXCEPT: TA development of resistance to vaccines and antibiotics B excellent public health measures to control infections C evokiton of new organisms Spread of viruses In new geographic areas 24. Nipah virus isa new genus inthe Paramyxoviidae family same as vnich "A West Nile wus 8. Corona weus C. Hendra virus Ebola virus For nos. 25 to 30, match the virus with the animal vectorireservoirlcarrier A. thoroughored horses © 25. Hanta rus, D 25. Npah ves Bcynomalgous monkeys ‘A2T Hendra rus deer mouse 828 Ebola vies domestic swine F 29, Coronaveus E migratory birds Foe cats E30, West Nile virus Choose the Best answer 38. The diagnosis ofa rotavirus infection is cinched by: '& solely on clinical presentation B routine electron microscopy of stoo! ©. increase in antibody titer D epidemiologic grounds i there is ongoing epidemic 39. Management f rotavirus infection is primary "A fluid and electrolyte replacement eB antviral drug insect vector control 1 isolaén and quarantine fache and nuchal rigidity. You suspect viral encephalitis ‘A young git coming from an agricultural farm arrived inthe ER with he ‘Which ofthe flowing viruses 's most likely involved C. Dengue viruses a "A. West Nile virus B. Japanese B D. malaria 42. Non-human vertebrate hosts for arboviral infections include: A. pigs D. allofthe choices 8 avian E. AandBonly ©. horses: 43, Dengue virus can cause ‘A Iytic infection ©. both A and B D. neither A nor B B. persistent infection 44. The mosquto vector for Dengue viruses: ©. Anopleles spp. A. Redes aegypti B. culex pipiens D.Phiebotomus spp 45, Which ofthe following can_be prevented by a vaccine ? ‘A Japanese encephalitis, C. Dengue fever B Mad Cow's Disease D. Aand Bare correct 46 P ‘and control of Dengue virus include: ‘Aciminaton of breeding places of Culex sp 8 provision of reliable water supply fogging, use of replians and screen 0. all are correct. E Band C are correctA. Togawiae ©. Flaviviridae Aphad Bungavinda one Sow sot a tagious disease A Dengue Cr Measles Mange 1B nfuenza A Hepaie 6. thrombocytopenia 8 Nephi © encephaitis laboratory agnosis of Congenital Rubella Syndrome relies on or Re caitam an cature G, Rabela IgM in les than 12 mon 8 ubelaly intess than @ months 0 Rubela igs at bith bs rete con (© Mon Fatal i 1. The virus is bullet shaped hence the name rhabdovirus | E) Woves have the lowest susceptibilty | Facial bites are non significant 52. Regarding rhabdovirus replication the following Isfare true "A There are 10 virion proteins Polymerase proteins contain only one type of protein . Rabies virus attach to cell sites via glycoprotein spikes D. Alaretwue setae aes hy inetiere Ssoan eee feet pecine Serna tpeoeess 54, This type of infectious hepatitis is classified as a Flevivius ‘A HepB B HepA C.HepC — D.Hep.O '55. Most common cause of epidemic encephaitis in north America ‘A. St-Louis encephalitis ©. West Nile fever 8 Egetem equine encephaltis D. Japanese encephaitis 56. Vector insect of St Louis encephaltis ‘A Aedes B. Anopheles C.Culex D. Psorophora 57. The vector of Sandi fever ‘A. Redes triseriatus © Dermacentor andersoni 8, Phiebotomus papatasii Deer mouse 88. True of Hantavins pulmonary syndrome except ‘A Caused by sin nombre B. Vectors the deer mouse C. Causes pulmonary edema 0. Twofold rise rise in IgG antibody is acute and convalescent sera is. Diagnostic 59. The primary vector of Rift valey fever ‘ACulex — B.Anopheles —C. Aedes. ©. Sandtly 60. True of sandy fever except ‘A Caused by Dermacentor andersoni B. Bite of vector stats in small itching papules on the skin . Associated with miltary troops, sometimes mistaken for malaria, Large size of vectors can be blocked by nets E.Aand Donly 61. Leading cause of viral encephalitis in Asia ‘A German measles C. Japanese encephalitis62 Tie of Lassa fever ‘A May cause ransiont deatness 8 Diagnosis involves detection of IgM, and IgG by ELISA {C Name was taken from Lasea valley in Nigeria 0. Atotthe above E Band only 163. din hemerthage fever is also known as "A Argentine hemorthagic fever ‘8. Machupe hemorrhagi ever Lassatever 1 Venezuelan hemorthagic fever (64. The vector of Bolvian hemorrhagic fevers ‘& Doe mouse ‘G. Calomys callosus 8 Aedes mosquto © Sanaty Match columa A with column B column & Column 6 B 65, Canine species "A Hantavirus ‘A. 66, Peromyscus maniculatus 8 Rhabgowius 'D 67. Mastomys natalensis Argentine hemormnagec fever 68, Mus muscius 1. Lassa fever 69, Caloris musculus E LOM vius (Choose the BEST answer 70, Rubella also known as "A German measies —_C_ 3.day measles B Rubeola 1D. Aand only 1 True of postnatal ube Pa Tne mucosa of the lower respiratory tract is mainly involved ‘antibodies coincide wth the development of rash i arthritis common in adults 1 immunity i ifelong 72. The standard serologic test fr Rubella ‘ELISA ©. Fluorescence antibody test &: fl(temagglutination) fest. Complement fixation test 73. Regarding immunity to postnatal Rubella the following is rue "A. IgGis not an evidence of immunity B. Iteonfers lifelong immunity C. There is a pathognomonic rash 1D. Nasopharyngeal or throat swabs are poor sources ofthe virus 74, Rubella virus belongs to what family A. Togaviridae ©. Flaviviridae: B. Paramyxoviridae © Orthovirdae 75. Whyis postnatal rubala infection called 3 day measles ‘A. The antibody response is 3 days B. Therash rarely lasts more than 3 days C. The vis persis in the blood for 3 days D. lgMantibodies remain for 3 days: 78. Fora patient wth Rubella, management includes ‘A. Fluids . Proper nutrition B Bedrest D. Allofthe choices 77. Regarding congenital rubella the following are true 'A The earlier the pregnancy, the lesser damage to the fetus8. Greatest percentagy e C. Bith defects are uncommon after the 20" week 8. Thetiad 8 congenital rubella includes, cataracts, heart abnormalities and ich palate C Deafness 0. Speech defects A Bindness. BC (79. Most common developmental manifestaton in congenta rubella 1K Mental retardation ‘aint B. Socal maladjustment D Allofthe choices | 00. infants wansientmanitestations are as follows except ' Glonth retardation Jaundice | B. Menngcencephaitis E Rash ©. Cet palate | a1. Form of maternal rubella transferred to the fetus bythe mother AWM B IgG Cig D. 1gD | az to ct ran es Sok rele eae eet Gecera tated arroyo 2 ee mas Somat ati rome ateeanmee eee fa ee hae ) i= ace ee ane Settee B. Lympadenopathy (© Worst form of viral exanthema 8 Thecare of a dog bte includes "A. wash wound vith soap and warm water Boose suturing 's done only when there is extensive laceration C. wound is infitrated wth hypermmune serum » D. allofthe above 186. Which ofthe folowing statements best describes rabies virusdisease [A has mutiple antigenic type ©. tteanbe transmitted by a dog weeks before the dog becomes noticeably il ean be isolated rom the blood of infected patients , 0. Alofthe above 187. Encephaliis isere caused by which ofthe following viruses? ‘A. Togaviruses C Rabies virus Herpes simplex 4. All three viruses. ‘88. Which ofthe flowing slow viruses is traced to sheep ? A kau C. Scrapie BO Duc 189. This is symptom is common among those with slow viruses infection A ataxia © anorexia 8. diplopia 1D. muscle wasting 90, The decision to give rabies vaccine is influenced by any of the following EXCEPT AA the condition of the animal at the time of exposure ‘A. the part ofthe body that was bitten the condition of the animal 15 days after exposure the severity ofthe bite DL none of the choices 1. Modes of transmission of rabies include the following EXCEPT ‘A bites of cat BB. scratches, Abrasions, open wounds or mucous membrane licked by @ rabid animal C. rat bites