Name:________________________________________________

Genetics Practice Problems

1. For each genotype below, indicate whether it is heterozygous (He) or homozygous (Ho)

AA _____ Ee _____ Ii _____ Mm _____

Bb _____ ff _____ Jj _____ nn _____
Cc _____ GG _____ kk ____ OO _____
Dd _____ HH _____ Ll ____ Pp _____

2. For each of the genotypes below determine what phenotypes would be possible.
P
Purple flowers are dominant to white Brown eyes are dominant to blue
PP _____________ BB ___________
Pp _____________ Bb ____________
pp ______________ bb _____________

Round seeds are dominant to wrinkled Bobtails are recessive (to long tails)
RR ______________ TT ____________
Rr ______________ Tt ____________
rr _______________ tt _____________

3. For each phenotype below, list the genotypes (remember to use the letter of the dominant trait)

Straight hair is dominant to curly Tail spikes are dominant to plain

tails
_____ straight ____ spikes
_____ straight ____ spikes
_____ curly ____ plain

4. Set up the Punnett squares for each of the crosses listed below. Purple flowers are dominant to white.

Rr x rr
What percentage will What percentage
be purple? will be white?

Rr x Rr
What percentage will What percentage
be purple? will be white?

RR x Rr
What percentage will What percentage
be purple? will be white?

Practice with Crosses. Show all work!

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5. A TT (tall) plant is crossed with a tt (short plant).

10. A white flowered plant is crossed with a plant that is

heterozygous for the trait.

What percentage of the offspring will be tall?

___________

6. Show the cross of a Tt plant and a Tt plant. What percentage of the offspring will have purple
flowers? _______ White
flowers? _______

11. Two plants, both heterozygous

for the gene that controls
What percentage of the offspring will be short? ______ flower colors are crossed.
What percentage is tall? _______

7. A heterozygous round seeded plant (Rr) is crossed

with a homozygous round seeded plant (RR).
What percentage of their offspring will have purple
flowers? _________
What percentage will have white flowers? _________

What percentage of the offspring will be homozygous
(RR)? _______
8. A homozygous round seeded plant is crossed with a
homozygous wrinkled seeded plant. What are the
genotypes of the parents?
__________ x __________
12. In guinea pigs, the allele for short hair is dominant.
What genotype would a heterozygous short haired
guinea pig have? ____
What genotype would a pure breeding short haired
guinea pig have?____
What genotype would a long-haired guinea pig have?
____

What percentage of the offspring will also be

homozygous? ________
Show the cross for two heterozygous guinea pigs.
What is the genotype of all of the offspring? ___

9. In pea plants purple flowers are dominant to white

flowers.

Two white flowered plants are crossed…

What percentage of the offspring will have short hair?
What percentage of their offspring will have white
flowers? ________ ________
What percentage of the offspring will have long hair?
_______

Name ___________________________________________Date:_______
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Genetic Crosses that Involve 2 Traits

In rabbits, Grey hair is dominant to white hair. Also in rabbits,

black eyes are dominant to red eyes.

GG = grey hair BB = black eyes

Gg = grey hair Bb = black eyes
gg = white hair bb = red eyes

1. What are the phenotypes (descriptions) of rabbits that have the following genotypes:

Ggbb ____________________ ggBB ________________________

ggbb ____________________ GgBb _________________________

2. A male rabbit with the genotype GGbb is crossed with a female rabbit with the genotype ggBb The square is
set up below. Fill it out and determine the phenotypes and proportions in the offspring.

Gb Gb Gb Gb
How many out of 16 are:
gB
Grey, red eyed ____
gB Grey, black eyed ____
gb White, red eyed ____

gb White, black eyed ____

3. A male rabbit with the genotype GgBb is crossed with a female rabbit with the genotype GgBb The square is
set up below. Fill it out and determine the phenotypes and proportions in the offspring.

Gb GB gB gb
How many out of 16 are:
Gb
Grey, red eyed ____
GB
Grey, black eyed ____

gB White, red eyed ____

White, black eyed ____
gb

4. Set this one up on the back of this page. A male rabbit with genotype GgBb x with a female rabbit with
genotype ggbb. Show the Punnett square and the expected offspring and their proportions.
Name _______________________________________
Practice Problems: Sex Linked Genes
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 ****In fruit flies, eye color is a sex-linked trait. Red is dominant to white ****

1. What are the sexes and eye colors of flies with the following genotypes:

XRXr _____________ XRY ____________ XrXr ____________

XRXR ____________ XrY ____________

2. What are the genotypes of these flies:

white eyed, male ____________ red eyed female (heterozygous) ________

white eyed, female ___________ red eyed, male ___________

3. Show the cross of a white eyed female X

r
Xr with a red-eyed male X
R
Y .

How many are:

white eyed, male ____
white eyed, female ____
red eyed, male ____
red eyed, female ____

4. Show a cross between a pure red eyed female and a white eyed male.
What are the genotypes of the parents:
___________& _______________

How many are:

white eyed, male ____
white eyed, female ____
red eyed, male ____
red eyed, female ____

5. Show the cross of a red eyed female (heterozygous) and a red eyed male. What are the genotypes of the
parents?
___________ & ____________

How many are:

white eyed, male____
white eyed, female ___
red eyed, male ____
red eyed, female ____
Math Problem: If the cross produce 100 males and 200 females,
how many TOTAL red-eyed flies would be expected? _____

Human Sex-Linkage
In humans, hemophilia is a sex-linked trait. Females can be normal, carriers, or have the disease. Males will
either have the disease or not (but they won’t ever be carriers)
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 = female, normal
= male, normal

= female, carrier
= male, hemophiliac

= female, hemophiliac

6. Show the cross of a man who has hemophilia with a woman who is normal (not a carrier).

How many children will have the disease? _____

7. A woman who is a carrier marries a normal man. Show the cross:

How many children will have the disease?

_____

What is the sex of the child with the disease? _____

8. A woman who has hemophilia marries a normal man.

How many children will have the disease?

_____

What is the sex of the child with the disease? _____

9. In cats, the gene for calico (multicolored) cats is codominant. Females that receive a B and an R gene have
black and oRange splotches on white coats. Males can only be black or orange, but never calico.
Show the cross of a female calico cat with a black male;

Female, calico = XB XR Male, black = XB Y

How many offspring will be:

Female and calico ____ Female and black ____

Male and black ___ Male and orange ___
Male and calico ____

10. Show the cross of a female black cat and a male orange cat.

What percentage of the kittens will be calico and female? _____

What color will all the male cats be? _____

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