28/07/2020 Introduction to Mechanobiology - - Unit 2 - Week 1

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Unit 2 - Week 1

Course
outline Week1_Assignment1
How to access The due date for submitting this assignment has passed. Due on 2019-08-14, 23:59 IST.
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Week 1 1) The ________ provides a firm substrate and support for cell adhesion. 1 point

Lecture 1: Need Plasma membrane

to Study Extracellular Matrix
Mechanobiology
Cytoskeleton
(unit?
unit=5&lesson=6) Focal adhesions

Lecture 2: Cell No, the answer is incorrect.

Score: 0
as a Tent,
Individual Accepted Answers:
Components Extracellular Matrix
(unit?
2) Cell A responds to a stimulus through ECM proteins and cytoskeletal network while Cell B 1 point
unit=5&lesson=7)
responds to the same stimulus via secondary messenger, cyclic AMP. Which cell would respond first to
Lecture 3 : Cell- the same stimulus?
ECM Crosstalk
(unit? Cell A
unit=5&lesson=8)
Cell B
Lecture 4 : ECM No, the answer is incorrect.
Proteins: Score: 0
Collagen (unit? Accepted Answers:
unit=5&lesson=9) Cell A
Lecture 5 : 3) In muscular dystrophy, apoptosis occurs in gsg (Limb girdle MD) cells but not in mdx 1 point
Measuring
(Duchene MD) cells due to
Properties of
Collagen
Low contractility of gsg cells and high contractility of mdx cells
Networks (unit?
unit=5&lesson=10) High contractility of gsg cells and low contractility of mdx cells
High contractility of gsg cells and balance between contractility and adhesion in mdx cells

https://onlinecourses.nptel.ac.in/noc19_bt30/unit?unit=5&assessment=82 1/3
28/07/2020 Introduction to Mechanobiology - - Unit 2 - Week 1

Download Low contractility of mdx cells and balance between contractility and adhesion in gsg cells
videos (unit?
No, the answer is incorrect.
unit=5&lesson=11)
Score: 0
Quiz : Accepted Answers:
Week1_Assignment1 High contractility of gsg cells and balance between contractility and adhesion in mdx cells
(assessment?
4) In the absence of any external factors, fibroblasts will migrate more persistently on 1 point
name=82)

Assignment 1 An aligned matrix

solutions (unit? A non-aligned matrix
unit=5&lesson=88)
A random matrix
Weekly They will migrate similarly on both the matrices
Feedback (unit?
unit=5&lesson=12) No, the answer is incorrect.
Score: 0
Week 2 Accepted Answers:
An aligned matrix
Week 3 5) ECM degradation by MMPs in cancer cells aids in 1 point

Week 4 assembly of cells into tissues

invasion from one part of the body to another
Week 5 membrane synthesis
nuclear re-organization
Week 6
No, the answer is incorrect.
Score: 0
Week 7
Accepted Answers:
invasion from one part of the body to another
Week 8
6) RBCs lack which of the following? 1 point
Text Transcripts
Plasma membrane
Mitochondria
Focal adhesions
Cytoskeleton
No, the answer is incorrect.
Score: 0
Accepted Answers:
Focal adhesions

7) Cells breach the basal lamina under which of the following conditions? 1 point

Immune surveillance
Cancer invasion
Both a and b
None of the above
No, the answer is incorrect.
Score: 0
Accepted Answers:
Both a and b

8) Cell spreading is higher on soft polyacrylamide gel of lesser thickness than on gels of higher 1 point
thickness of the same stiffness because

Cells sense the aggregate stiffness of the soft gel and the stiff glass beneath the gel
Cells sense only the stiff glass underneath the soft gel
Cells lose their properties of sensing the substrate stiffness on soft gels

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28/07/2020 Introduction to Mechanobiology - - Unit 2 - Week 1

None of the above

No, the answer is incorrect.
Score: 0
Accepted Answers:
Cells sense the aggregate stiffness of the soft gel and the stiff glass beneath the gel

9) ________ provides tensile strength to the tissues and it is secreted by _________ cells. 1 point

Vinculin, epithelial
Collagen, immune
Talin, immune
Collagen, fibroblast
No, the answer is incorrect.
Score: 0
Accepted Answers:
Collagen, fibroblast

10)The major structural component of basement membrane 1 point

Collagen type I
Collagen type II
Collagen type III
Collagen type IV
No, the answer is incorrect.
Score: 0
Accepted Answers:
Collagen type IV

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