• TOP 10 TAKE-HOME MESSAGES FOR THE SECONDARY STROKE PREVENTION GUIDELINE

• PREAMBLE

1. INTRODUCTION

1.1 Methodology and Evidence Review

1.2 Organization of the Writing Group
1.3 Document Review and Approval
1.4 Scope of the Guideline
1.5 Class of Recommendation and Level of Evidence
1.6 Abbreviations

2. GENERAL CONCEPTS

2.1 Definitions
2.2 Shared Decision-Making
2.3 Contraindications
2.4 Adherence
2.5 Antithrombotic Dosing
2.6 Application Across Populations

3. DIAGNOSTIC EVALUATION FOR SECONDARY STROKE PREVENTION

4. VASCULAR RISK FACTOR MANAGEMENT

4.1 Lifestyle
4.1.1 Nutrition
4.1.2 Physical Activity
4.1.3 Smoking Cessation
4.1.4 Substance Use
4.2 Hypertension
4.3 Treatment of Hyperlipidemia for Secondary Prevention of Stroke
4.3.1 Treatment and Monitoring of Blood Lipids for Secondary Stroke Prevention
4.3.2 Treatment of Hypertriglyceridemia
4.4 Glucose
4.5 Obesity
4.6 Obstructive Sleep Apnea

5. MANAGEMENT BY ETIOLOGY

5.1 Large Artery Atherosclerosis

5.1.1 Intracranial Large Artery Atherosclerosis
5.1.2 Extracranial Large Artery Atherosclerosis
5.1.2.1 Extracranial Carotid Stenosis
5.1.2.2 Extracranial Vertebral Artery Stenosis
5.1.3 Aortic Arch Atherosclerosis
5.2 Moyamoya Disease
5.3 Ischemic Stroke Caused by Small Vessel Disease
5.4 Cardioembolism
5.4.1 Atrial Fibrillation
5.4.2 Valvular Disease
 5.4.3 LV Thrombus
5.4.4 Cardiomyopathy
5.4.5 Patent Foramen Ovale
5.5 Congenital Heart Disease
5.6 Cardiac Tumors
5.7 Dissection
5.8 Hypercoagulable States
5.8.1 Hematologic Traits
5.8.2 Antiphospholipid Syndrome
5.9 Hyperhomocysteinemia
5.10 Migraine
5.11 Malignancy
5.12 Sickle Cell Disease
5.13 Vasculitis
5.13.1 Autoimmune Vasculitis
5.13.2 Infectious Vasculitis
5.13.3 Neoplastic Vasculitis
5.14 Other Genetic Disorders
5.15 Carotid Web
5.16 Fibromuscular Dysplasia
5.17 Dolichoectasia
5.18 Embolic Stroke of Undetermined Source
5.19 Use of Antithrombotic Medications in Secondary Stroke Prevention

6. SYSTEMS OF CARE FOR SECONDARY PREVENTION

6.1 Health Systems–Based Interventions for Secondary Stroke Prevention

6.2 Interventions Aimed at Changing Patient Behavior
6.3 Health Equity

• AHA STROKE COUNCIL SCIENTIFIC STATEMENT OVERSIGHT COMMITTEE

• PRESIDENT AND STAFF

• ARTICLE INFORMATION

• Appendix 1

• Appendix 2

• REFERENCES