DRUG STUDY

Date Generic Brand Classification Indication Mechanism of Dosage Adverse Nursing

Name Name Action and Reaction Considerations
Frequency
Medroxy Provera Therapeutic: To decrease A synthetic form of CNS:  Monitor signs
progeste antineoplasti endometrial progesterone depression. of
rone hyperplasia in actions include EENT: retinal
cs, thrombophle
postmenopau secretory changes thrombosis.
contraceptiv sal women in the bitis (localized
e hormones CV: pain, swelling,
receiving endometrium,
PULMONARY warmth,
Pharmacolog concurrent increases in basal
estrogen body temperature, EMBOLISM,
ic: erythema,
(0.625 histologic changes thromboemb
hormones, tenderness)
mg/day in vaginal olism,
progestins thrombophle
and
conjugated epithelium,
estrogens). relaxation of bitis. GI: drug- pulmonary
Treatment of uterine smooth induced embolism
secondary muscle, mammary hepatitis, (shortness of
amenorrhea alveolar tissue gingival breath, chest
and abnormal growth, pituitary bleeding. pain, cough,
uterine inhibition, and
GU: cervical bloody
bleeding withdrawal
caused by bleeding in the erosions. sputum).
hormonal presence of Derm: Notify
imbalance. estrogen. chloasma, physician
IM: Therapeutic Effects: melasma, immediately,
Treatment of Decreased rashes. Endo: and request
advanced endometrial amenorrhea,
unresponsive hyperplasia in
objective
breakthrough
endometrial postmenopausal tests (Doppler
bleeding,
or renal women receiving ultrasound,
breast
carcinoma; concurrent lung scan,
tenderness,
Management estrogen others) if
changes in
of (combination with
endometriosi estrogen decreases menstrual thromboemb
s-associated vasomotor flow, olism is
pain (Depo- symptoms and galactorrhea, suspected.
Sub Q prevents
hyperglycemi  Monitor signs
Provera 104 osteoporosis).
a, spotting.
only). Restoration of of allergic
Unlabeled hormonal balance F and E: reactions
Use: Obesity- with control of edema.
including
hypoventilati uterine bleeding. Metab: bone
anaphylaxis
on Management of loss. Misc:
(pickwickian) endometrial or ALLERGIC
and
syndrome, renal cancer. REACTIONS, angioedema.
sleep apnea, Prevention of INCLUDING Signs include
hypersomnol pregnancy. ANAPHYLAXIS pulmonary
ence. AND symptoms
ANGIOEDEMA (tightness in
, weight gain, the chest and
weight loss. throat,
wheezing,
cough,
dyspnea) or
skin reactions
(rash,
pruritus,
urticaria,
swelling in
the face).
Notify
physician
immediately if
these
 reactions
occur.

 Assess
peripheral
edema using
girth
measurement
s, volume
displacement,
and
measurement
of pitting
edema.
Report
increased
swelling in
feet and
ankles or a
sudden
increase in
body weight
due to fluid
retention.

 Report signs
of drug-
induced
 hepatitis,
including
anorexia,
abdominal
pain, severe
nausea and
vomiting,
yellow skin or
eyes, skin
rashes, flu-
like
symptoms,
and
muscle/joint
pain.
 Monitor and
report
depression or
other changes
in mood and
behavior.
 Periodically
assess body
weight and
other
anthropometr
ic measures
(body mass
index, body
composition).
Report a rapid
or sustained
weight loss or
gain, or a
substantial
change in
lean body
mass.