ajog.
org
1). In regression analyses, Black and Latin-X ethnicity was signifi-
cantly associated with decreased odds of receiving aneuploidy
screening after adjusting for gestational age at first prenatal visit (OR
0.86 95% CI [0.78-0.96], p¼0.004).
CONCLUSION: Disparities in use of reproductive genetic services
among Black and Latin-X patients compared to White peers likely
illustrate larger inequities in obstetric care. Future research should
focus on barriers to accessing care and the impact of systemic racism
on receipt of genetic services.
982 COVID-19 infection and diabetes in pregnancy
Erica Aibangbee, Rachel Paul, Jonathan S. Hirshberg,
Anthony O. Odibo, Jeannie C. Kelly,
Nandini Raghuraman, Ebony B. Carter
Washington University School of Medicine, St. Louis, MO
OBJECTIVE: Diabetes is associated with a more severe SARS-CoV-2
infection phenotype in non-pregnant individuals. However, there is
a limited information about this relationship in pregnancy. We
sought to determine whether pregnant patients with diabetes are
more likely to have severe COVID-19 infection than pregnant pa-
tients without diabetes.
STUDY DESIGN: This is a retrospective case-control study of all pa-
tients delivering at Barnes-Jewish Hospital from June 2020eMay
2021 that had a positive COVID-19 test during pregnancy. The labor
and delivery unit offered universal SARS-CoV-2 testing to all pa-
tients. Patient characteristics, including diabetes in pregnancy, were
extracted from the medical record. Descriptive statistics were used to
characterize the cohort and bivariate analyses were used to compare
patients non-severe disease to patients with severe COVID-19 dis-
ease based on WHOOSCI and NCPERET criteria (dyspnea,
Supplement to JANUARY 2022 American Journal of Obstetrics & Gynecology
Poster Session IV
respiratory rate 30 breaths per minute, blood oxygen saturation of
93%, PaO2/FiO2 ratio < 300, lung infiltrates involving >50% on
imaging, non-invasive ventilation or high flow oxygen use, intuba-
tion and mechanical ventilation, ventilation with additional organ
support).
RESULTS: There were 198 patients with a positive COVID-19 test
during pregnancy: 18 (9.1%) had diabetes (pre-gestational or
gestational diabetes mellitus) in pregnancy, and 49 (24.7%) had
severe COVID-19 disease. Compared to those with non-severe dis-
ease, patients with severe COVID-19 were diagnosed with COVID-
19 at an earlier gestational age (29.6 weeks vs 33.3 weeks, p¼0.033).
Patients with severe COVID-19 were not more likely to have diabetes
(10.2% vs. 8.7%, p¼0.777). Post-hoc power analyses revealed the
sample was underpowered to see a difference between the groups.
CONCLUSION: In this cohort, diabetes in pregnancy did not confer
additional risk of severe COVID-19 disease. Similar analyses in larger
samples may provide greater understanding regarding the associa-
tion between severe COVID-19 and diabetes in pregnancy.
983 Longitudinal ultrasound evaluation of
Dilapan-S diameter during cervical ripening
Elizabeth Seagraves1, Jerri A. Waller1, Tracey DeYoung1,
Carole Barake2, Tetsuya Kawakita1, Camille Kanaan1,
Alfred Abuhamad1
1
Eastern Virginia Medical School, Norfolk, VA, 2University of Texas Medical
Branch, Galveston, TX
OBJECTIVE: Dilapan-S is commonly inserted in the cervix for a 12-24
hour duration. In vitro evaluation has shown that Dilapan-S rods
reach near maximum dilation within 6 to 8 hours. Using trans-
vaginal ultrasound, we sought to evaluate the diameter rate-change
of each Dilapan-S rod during cervical ripening. We also evaluated
whether soaked gauze placement affects the rate of Dilapan-S
diameter change over time.
STUDY DESIGN: This was a prospective longitudinal study of term
women undergoing labor induction with a bishop score < 6.
Women were randomized into two groups (soaked gauze or no
gauze) stratified by parity. Using transvaginal ultrasound, maximal
Dilapan-S diameters were obtained in a longitudinal plane (Figure
1). Measurements were taken at 4 pre-specified time points (3, 6, 8,
and 12 hours). All Dilapan-S were removed at 12 hours from
S627