DRUG DATA AND MECHANISM OF INDICATIONS CONTRAINDICATIONS SIDE EFFECTS NURSING

CLASSIFICATION ACTION RESPONSIBILITIES

Contractions are Acute pelvic  Nausea  Monitor uterine

qualitatively similar to inflammatory disease, contractions and
Generic Name: Dinoprostone is a  Vomiting
naturally occurring those that occur during history of pelvic surgery, observe for and
Prostin
prostaglandin E2 (PGE2). term labor. Has high uterine fibroids, cervical  Diarrhea report excessive
Brand Name: It has important effects in success rate when used stenosis, active cardiac,  Fever vaginal bleeding
labour. It also stimulates as abortifacient before pulmonary, renal, or and cramping
Cervidil, Prostin E2 , osteoblasts to release twentieth week and for hepatic disease,  Chills pain. Keep pad
Prepidil factors which stimualtes stimulation of labor in pregnancy (category C). count. Save all
 Stomach or
Dosage: bone resorption by cases of intrauterine fetal abdominal pain clots and tissues
osteoclasts. As a death for physician
0.5 mg Gel/10mg Vaginal prescription drug it is  Back pain inspection and
Insert used as a vaginal laboratory
 Flushing
suppository, to prepare analysis.
Route:
the cervix for labour and  Chest pain
Endocervical to induce labour.  Monitor vital
 Dyspnea
Intravaginal signs. Fever is a
physiologic
response of the
Frequency: hypothalamus to
use of
12 hours after insertion
dinoprostone and
3 to 5 hours occurs within 15–
45 min after
Appearance:
insertion of
suppository.
Temperature
returns to normal
 within 2–6 h after
discontinuation
of medication.

 Continue taking
your temperature
(late afternoon)
for a few days
after discharge.
Contact
physician with
onset of fever,
bleeding,
abdominal
cramps, abnormal
or foul-smelling
vaginal discharge

REFERENCES:
http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/D053.html
https://www.rxlist.com/prostin-e2-drug.htm#side_effects
https://go.drugbank.com/drugs/DB00917

ProstinE2.pdf (medsafe.govt.nz)
 DRUG DATA AND MECHANISM OF INDICATIONS CONTRAINDICATIONS SIDE EFFECTS NURSING
CLASSIFICATION ACTION RESPONSIBILITIES

Sulbactam is an This combination The use of UNASYN is  Fever Assessment & Drug
irreversible inhibitor of medication is used to contraindicated in Effects
Generic Name:  sore throat
β-lactamase; by binding treat a wide variety of individuals with a history
Sulbactam and inhibiting β- bacterial infections. It is of serious  headache  Determine
lactamase produced by known as a penicillin- hypersensitivity
 rash previous
Brand Name: bacterial cells, sulbactam type antibiotic. It works reactions (e.g., hypersensitivity
Unasyn is thereby able to prevent by stopping the growth anaphylaxis or Stevens-  diarrhea reactions to
it from reducing of bacteria Johnson syndrome) to penicillins,
Dosage:  body aches
antibiotic activity. ampicillin, sulbactam or cephalosporins,
to other beta-lactam  nausea
1.5 (1 g ampicillin, 0.5 g and other
antibacterial drugs (e.g.,
sulbactam) to  vomiting allergens prior to
penicillins and
3 g (2 g ampicillin, 1 g cephalosporins).  stomach pain
therapy.
sulbactam)  Lab tests:
 bloating Baseline C&S
q6h (max: 4 g tests prior to
 gas
sulbactam/d) initiation of
 vaginal itching or
Route: therapy; start
discharge,
drug pending
IM/IV  itching, results.
Frequency:  swollen/black/"hairy"  Report promptly
tongue unexplained
q6h
bleeding (e.g.,
 thrush (white patches
Appearance: inside your mouth or
epistaxis,
throat), or purpura,
ecchymoses).
 pain, swelling, or  Monitor patient
irritation where the
carefully during
needle is placed. the first 30 min
after initiation of
IV therapy for
signs of
hypersensitivity
and
anaphylactoid
reaction (see
Appendix F).
Serious
anaphylactoid
reactions require
immediate use of
emergency drugs
and airway
management.
 Observe for and
report symptoms
of
superinfections
(see Appendix
F). Withhold
drug and notify
physician.
 Monitor I&O
ratio and pattern.
Report dysuria,
urine retention,
and hematuria.
 Patient & Family
Education

 Report chills,
wheezing,
pruritus (itching),
respiratory
distress, or
palpitations to
physician
immediately.
 Do not breast
feed while taking
this drug without
consulting
physician.

REFERENCES: Monograph (robholland.com)

Unasyn (Ampicillin and Sulbactam): Uses, Dosage, Side Effects, Interactions, Warning (rxlist.com)

Sulbactam | C8H11NO5S - PubChem (nih.gov)

Unasyn Intravenous: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD