Unisite Subdivision, Del Pilar, City of San Fernando, 2000 Pampanga,

Philippines

DRUG STUDY
(Module Requirement RLE-109)

Submitted by:

LAPUZ, Yna Rose Ann S.

BSN-2A

Submitted to:
Mrs. Marie Aileen L. Domingo, RN
Mrs. Cherry B. Lazatin, RN, RPh, MAN
Mrs. Christy G. Tuazon, RN
Mrs. Phoebe Queen P. Mallari, RN

February 21, 2022

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 Drugs Classification Mechanism of Indications Contraindications Side Effects Nursing Responsibilities
Action
Generic Name: Clindamycin Vaginal • Clindamycin History of Side effects: • Monitor signs of
Clindamycin-C belongs to a clindamycin is used is indicated hypersensitivity to • white patches in
class of drugs to treat bacterial in the clindamycin or pseudomembranous colitis,
the mouth
Brand name: called vaginosis (an treatment of lincomycin; history including diarrhea, abdominal
• thick, white
Cleocin, Dalacin Lincomycin infection caused by serious of regional
C, Antibiotics an overgrowth of enteritis, vaginal discharge pain, fever, pus, or mucus in stools,
infections
harmful bacteria in caused by ulcerative colitis, • burning, itching, and other severe or prolonged GI
Appearance: Pregnancy the vagina). susceptible or antibiotic- and swelling of problems (nausea, vomiting,
category: B Clindamycin is in a anaerobic associated colitis; the vagina
class of bacteria. pregnancy heartburn). Notify physician or
• burning, painful
medications called (category B), nursing staff immediately of these
lincomycin • Clindamycin lactation. urination
antibiotics. It • vaginal pain signs.
is also
works by slowing indicated in • constipation
or stopping the the treatment • nausea • Assess dizziness or vertigo
Available Dosage: growth of bacteria. of serious
75 mg • headache that might affect gait, balance, and
infections due
150 mg • back pain
to susceptible other functional activities. Report
300 mg capsules;
strains of
75 mg/5 mL oral Adverse effects: balance problems and functional
streptococci,
suspension • stomach pain or limitations to the physician and
pneumococci,
150 mg/mL
and cramping nursing staff and caution the
injection
staphylococci. • diarrhea
2% vaginal cream; patient and family/caregivers to
100 mg • watery or bloody
guard against falls and trauma.
suppositories stools
10 mg gel, • fever
lotion; 1% foam • Assess heart rate, ECG, and
• blisters
Route of • rash heart sounds, especially during
administration: • hives exercise. Report any rhythm
• Oral • itching
disturbances or symptoms of
• IM
• IV increased arrhythmias, including

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• Intravaginal • difficulty
palpitations, chest discomfort,
breathing or
swallowing shortness of breath, fainting, and
fatigue/weakness.

• Assess blood pressure

periodically and compare to
normal values. Report low blood
pressure (hypotension), especially
if patient experiences dizziness,
fatigue, or other symptoms.

• Monitor injection site for

pain, swelling, and irritation.
Report prolonged or excessive
injection site reactions to the
physician.

Patient/Client-Related
Instruction
• Advise patient about the
likelihood of GI reactions such as
nausea, vomiting, diarrhea, and
taste abnormalities. Instruct
patient to report severe or
prolonged GI problems.

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• Instruct patient and
family/caregivers to report other
troublesome side effects.
• Take drug for the full course of
therapy as prescribed.
• Advise to report loose stools or
diarrhea promptly.
• Advise to stop drug therapy if
significant diarrhea develops
(more than 5 loose stools daily)
and notify physician.
• Educate to not self-medicate with
antidiarrheal preparations.
Antiperistalsis agents may
prolong and worsen diarrhea by
delaying removal of toxins from
colon.
• If using topical preparation for
acne, discontinue other acne
preparations unless otherwise
directed by physician. Keep
medication away from eyes.
• Advise patient to not breast feed
while taking this drug.

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 Drugs Classification Mechanism of Indications Contraindications Side Effects Nursing Responsibilities
Action
Generic name: Clavulanic acid It works by • To treat infections • Combination Side Effects: • Assess previous
Clavulanic Acid is in a class of stopping the caused by susceptible shares toxic • nausea, hypersensitivity reactions
medications growth of beta-lactamase- potential of • vomiting, to penicillin,
Brand name: called Beta- bacteria. It works producing organisms: ampicillin. • diarrhea, cephalosporins, and other
Augmentin, Co- Lactamase by preventing lower respiratory tract • Hypersensitivity • rash, allergens prior to therapy.
Amoxiclav, or Inhibitors. bacteria from infections, acute to penicillin; • itching, • Lab tests: Baseline
Clavulin. destroying bacterial sinusitis, infectious • vaginal itching or culture and sensitivity
Pregnancy amoxicillin. Used community acquired mononucleosis. discharge, and tests prior to initiation of
Appearance: category: B alone, clavulanic pneumonia, otitis • diaper rash therapy; start drug
acid antibacterial media, sinusitis, skin, pending results.
activity is weak. and skin structure Adverse Effects: • Monitor for signs
In combination, infections, and UTI. • hives, and symptoms of an
it inhibits • To reduce the • difficult urticarial rash (usually
enzyme (beta- development of drug occurring within a few
breathing,
lactamase) resistant bacteria and days after start of drug)
• swelling in your
Available degradation of maintain the suggestive of a
face or throat,
Dosage: amoxicillin and effectiveness of hypersensitivity reaction.
• 250 mg by synergism AUGMENTIN If it occurs, look for other
• fever,
• 500 mg extends both (amoxicillin/clavulanate signs of hypersensitivity
spectrum of • sore throat,
• 875 mg tablets potassium) and other (fever, wheezing,
activity and • burning eyes,
• 125 mg antibacterial drugs. generalized itching,
bactericidal • skin pain,
• 200 mg • Augmentin should be dyspnea), and report to
effect of • red or purple
• 400 mg used only to treat physician immediately.
amoxicillin skin rash with
chewable infections that are • Note for generalized,
against many proven or strongly blistering and
tablets. erythematous,
strains of beta- peeling,
• 125 mg/5 mL suspected to be caused maculopapular rash
lactamase- by susceptible bacteria. • severe stomach (ampicillin rash) is not due
• 200 mg/5 mL
producing pain,
• 250 mg/5 mL • When culture and to hypersensitivity. It is
bacteria resistant susceptibility • diarrhea that is usually mild but can be
• 400 mg/5 mL watery or bloody
information are severe.

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• 600 mg/5 mL to amoxicillin available, they should (even if it occurs • Report onset of rash
oral suspension. alone be considered in months after to physician, since
• 1000 mg selecting or modifying your last dose), hypersensitivity should be
amoxicillin/62.5 antibacterial therapy. • pale or yellowed ruled out.
mg clavulanate • In the absence of such skin,
sustained- data, local epidemiology • dark colored
release tablets and susceptibility urine, Patient & Family
patterns may contribute • fever, Education
Route of to the empiric selection • confusion,
administration: of therapy. • weakness, • Female patients
• IV • loss of appetite, should report onset
• Oral • upper stomach of symptoms
pain, of Candidal
• little or no vaginitis (e.g.,
urination, moderate amount of
• easy bruising, white, cheesy, non-
and odorous vaginal
• unusual bleeding discharge; vaginal
inflammation and
itching; vulvar
excoriation,
inflammation,
burning, itching).
Therapy may have to
be discontinued.
• Note: Use Clinistix or
TesTape when
monitoring urinary
glucose to avoid false
readings with
diabetes mellitus.
• Do not breast feed
while taking this drug

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without consulting
physician.

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References:
http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/C090.html?fbclid=IwA
R2EQ0ilRn7ncELmpV-PyqN8ijwcYf5G8KHsbe5ob1zslhyUQOK-EDpsfZA
https://www.mayoclinic.org/drugs-supplements/clindamycin-vaginal-route/proper-use/drg-
20063118?fbclid=IwAR3aDX9o0tJW1SBjCyPSfVfQ6ypS3iGHW8nEkXCF2hqn102pspvbD5lZJqo
https://fadavispt.mhmedical.com/content.aspx?bookid=1873&sectionid=139006009&fbclid=IwAR
1TSK6DsGnVB5bzYthVuNGYOs7_Lp7wONdaH0GGFSO7TMGhY8hfqlgpYdU
https://www.ncbi.nlm.nih.gov/books/NBK545273/
http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/A054.html
https://www.rxlist.com/cleocin-iv-drug.htm#description
https://www.rxlist.com/consumer_amoxicillinclavulanate_augmentin/drugs-condition.htm
https://medicalguidelines.msf.org/viewport/EssDr/english/amoxicillin-clavulanic-acid-co-
amoxiclav-oral-16685119.html
https://www.rxlist.com/augmentin-drug.htm#dosage

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