F.

Drug Study
Drug Dosage Action Indication/
Contraindications
Brand Name: Second-generation Indications:
500mg
Cefuroxime cephalosporin that Infections of the urinary
inhibits cell-wall and lower respiratory
Generic Name: synthesis, promoting tracts, and skin structure
Ceftin osmotic instability; infections.
usually Contraindication:
Route: bactericidal. • Contraindicated in
PO patients hypersensitive to
drug.
Frequency: • Use cautiously in
BID patients
hypersensitive to
Drug Classification: penicillin because of
Antibiotic possibility of cross
sensitivity with another
beta-lactam antibiotic.
• Use with caution in
breast-feeding women
and in patients with
history of colitis or renal
sufficiency.
Adverse Effects Nursing
Responsibilities
Diarrhea, nausea, • Determine history
rashes, decreased of hypersensitivity
creatinine clearance. reactions to
cephalosporins,
penicillins and history
of allergies,
particularly to drugs
before therapy is
initiated.
• Report onset of
loose stools.
• Absorption of
cefuroxime is
enhanced by food.
• Notify prescriber
about rashes or
superinfections.