Nursing

Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects

Responsibilities
Generic Name: Pharmacologic Preferentially binds to General Indications: Known hypersensitivity Body as a Whole: Before
Cefuroxime Class: one or more of the Treatment of the to cephalosporins; viral Thrombophlebitis (IV -Proper handwashing
antibiotic; second- penicillin-binding following infections infections site); pain, burning, -Check doctor’s order
Trade/Brand Name: generation proteins (PBP) located caused by susceptible cellulitis (IM site); -Determine history of
Ceftin, Zinacef cephalosporin on cell walls of organisms: *Use cautiously to superinfections, hypersensitivity
susceptible organisms. Respiratory tract patients with History of positive Coombs’ test. reactions to
Patients’ Dose: This inhibits third and infections, Skin and allergy, particularly to Gastro Intestinal: cephalosporins,
750 mg IVTT q 8H Therapeutic Class: final stage of bacterial skin structure drugs; cephalosporins Diarrhea, nausea, penicillins, and history
(-) ANST x 3 days Antibiotic cell wall synthesis, infections, Bone and or penicillin sensitivity; antibiotic associated of allergies, particularly
Route: Intravenous thus killing the joint infection, Urinary renal insufficiency; colitis. to drugs, before
Form: Parenteral Pregnancy Category bacterium. Similar to Tract Infections, history of seizures; Skin: Rash, pruritus, therapy is initiated.
B other second Meningitis, history of colitis or urticaria. -Monitor lab tests:
Maximum dose: generation gynecologic infections, other GI disease; Urogenital: Increased Culture and sensitivity
500 mg BID cephalosporins, and Lyme disease, pregnancy (category serum creatinine and tests before initiation
cefuroxime is more Otitis Media, B), lactation BUN, decreased of therapy. Therapy
Minimum dose: active against gram- Septicemia, and as creatinine clearance. may be instituted
250 mg BID negative bacteria than Perioperative Hematologic: pending test results.
are first-generation Prophylaxis Transient neutropenia, Periodic BUN and
Availability: cephalosporins but not eosinophilia, hemolytic creatinine clearance.
Tablets: 250 mg, as active as third- anemia, -Encourage patient to
500mg generation Patient’s Indication: thrombocytopenia eat before
cephalosporins. Prophylaxis for patient Respiratory: administration as it
Oral suspension is susceptible to Dyspnea enhances absorption
(tutti-frutti flavor): infection because of
125 mg/5 mL, 250 wound due to During
mg/5 mL. cesarean section Source: -Change sites every
surgery Source: Vallerand, A., Sanoski, 48–72 hr to prevent
Powder for injection: Vallerand, A., Sanoski, C., & Deglin, J. (2017). phlebitis -Monitor site
750 mg/vial, 1.5 g/vial, Source: Source: C., & Deglin, J. (2017). Drug Guide for frequently for
7.5 g/vial. Vallerand, A., Sanoski, Vallerand, A., Sanoski, Source: Drug Guide for Nurses. 15th Ed. FA thrombophlebitis
C., & Deglin, J. (2017). C., & Deglin, J. (2017). Vallerand, A., Sanoski, Nurses. 15th Ed. FA Davis Company: (pain, redness,
Premixed containers: Drug Guide for Drug Guide for C., & Deglin, J. (2017). Davis Company: Philadelphia swelling).
750 mg/50 mL, 1.5 Nurses. 15th Ed. FA Nurses. 15th Ed. FA Drug Guide for Philadelphia - If aminoglycosides
g/50 mL. Davis Company: Davis Company: Nurses. 15th Ed. FA Wilson, B., are administered
Philadelphia Philadelphia Davis Company: Wilson, B., Shannon, M. T., & concurrently,
Philadelphia Shannon, M. T., & Shields, K. M. administer in separate
Content:
Wilson, B., Wilson, B., Shields, K. M. (2015). Pearson sites if possible, at
Shannon, M. T., & Shannon, M. T., & Wilson, B., (2015). Pearson Nurses' Drug Guide. least 1 hr apart. If
Shields, K. M. Shields, K. M. Shannon, M. T., & Nurses' Drug Guide. www.pearsonhighered second site is
(2015). Pearson (2015). Pearson Shields, K. M. www.pearsonhighered. .com/drugguides unavailable, flush line
Source:
Nurses' Drug Guide. Nurses' Drug Guide. (2015). Pearson com/drugguides between medications.
Vallerand, A., Sanoski,
www.pearsonhighered. www.pearsonhighered Nurses' Drug Guide. - Monitor for
C., & Deglin, J. (2017). com/drugguides .com/drugguides www.pearsonhighered manifestations of
Drug Guide for .com/drugguides hypersensitivity.
Nurses. 15th Ed. FA Discontinue drug and
Davis Company: report their
Philadelphia appearance promptly
upon manifestations of
Wilson, B., hypersensitivity
Shannon, M. T., &
Shields, K. M. After
(2015). Pearson -Report onset of loose
Nurses' Drug Guide. stools or diarrhea.
www.pearsonhighered Pseudomembranous
.com/drugguides colitis should be ruled
out as the cause of
diarrhea during and
after antibiotic therapy.
-Instruct patient to
complete drug therapy
even when he/she
feels better
-Tell patient to avoid
alcohol while on drug
therapy to avoid
adverse reactions
-Prepare Vit. K in case
there are signs of
hypoprothrombinemia
-Document the drug
administration

Source:
Vallerand, A., Sanoski,
C., & Deglin, J. (2017).
Drug Guide for
Nurses. 15th Ed. FA
Davis Company:
Philadelphia

Wilson, B.,
Shannon, M. T., &
Shields, K. M.
(2015). Pearson
Nurses' Drug Guide.
www.pearsonhighered.
com/drugguides