Republic of the Philippines

UNIVERSITY OF EASTERN PHILIPPINES

University Town, Northern Samar

COLLEGE of NURSING and ALLIED HEALTH SCIENCES

DRUG ANALYSIS
 SPECIFIC CONTRAINDIC DRUG ADVERSE SPECIFIC NURSING
NAME OF DRUG INDICATION
ACTION ATION INTERACTION REACTION PRECAUTION RESPONSIBILITIES
Generic Name: Inhibits cell-wall Ceftriaxone is History of DRUG-DRUG GI: Diarrhea, anorexia, Obtain specimen for culture Obtain CBC, renal function
Ceftriaxone synthesis, promoting effective against a hypersensitivity/ glossitis, dyspepsia, and sensitivity test before tests. Question for history
osmotic instability, broad range of anaphyl Aminoglycosides: may abdominal cramps, giving first dose of allergies, particularly
Dosage: usually bactericidal bacteria and is actic reaction to pruritus cephalosporin, penicillin.
increase risk of
often used as a cephalosporins.
2g IV nephrotoxicity Before giving drug, ensure
first-line treatment Cautions: Severe
for suspected UTIs renal Skin: Rash, tenderness paitent isn’t allergic to Instruct patient to report
Route: impairment, history Anticoagulants: May at injection site penicillin or cephalosporin adverse reactions promptly
Intravenous Infusion of increase anticoagulant
(IV) penicillin allergy, effects Other specific precautions Tell patient to report
history involves pregnancy, discomfort at I.V. injection
Therapeutic Class: of seizures.
Antibiotics lactation, and reproduction site.
History of
which does not concern the
hypersensitivity/
Pharmacologic Class: anaphyl client
Third-generation actic reaction to
cephalosphorins cephalosporins.
Cautions: Severe
renal
Reference:
impairment, history
Nursing 2021Drug of
Handbook penicillin allergy,
history
of seizures.
Contraindicated in
patients
hypersensitive to
drug or other
cephalosphorins

Use cautiously in
patients
hypersensitive to
penicillin because
of the possibility of
cross-sensitivity
with other beta-
lactam antibiotics

Use cautiously in
patients with
history of colitis,
seizure disorder, or
renal insufficiency
 Republic of the Philippines
UNIVERSITY OF EASTERN PHILIPPINES
University Town, Northern Samar

COLLEGE of NURSING and ALLIED HEALTH SCIENCES

DRUG ANALYSIS

SPECIFIC CONTRAINDICA DRUG ADVERSE SPECIFIC NURSING

NAME OF DRUG INDICATION
ACTION TION INTERACTION REACTION PRECAUTION RESPONSIBILITIES
Generic Name: Inhibits proton Short Term Contraindicated in DRUG-DRUG GI: Abdominal pain, May increase LFT values Long term therapy may
Omeprazole pump activity by treatment of patients constipation, diarrhea, and falsely elevate serum cause vitamine b12
binding to active benign hypersensitive to Rifampin: May flatulence, nausea, chromogranin level, absorption problems.
hydrogen- gastric ulcer drug or its vomiting, acid Assess patient for signs and
substantially decrease
Brand Name: potassium components omeprazole regurgitation May decrease magnesium, symptoms of
Losec adenosine concentration sodium and glucose levels cyanocobalamin deficiency
triphosphates, in lab tests
Route: located at secretory Salicylates: Enteric- Monitor patients for signs
Intravenous (IV) surface of gastric coated forms may and symtpms of low
parietal cells, to dissolve faster, magnesium level, such as
Dose: suppress gastric increasing risk of gastric abnormal HR or rhythm,
40mg every 12 hours acid secretions adverse effects palpitations, muscle
spasms, tremors, or seizures

Therapeutic Class: Teach patient to recognize

Antiulcer and report signs and
symptoms of low
magnesium level
Reference:
Nursing 2021Drug
Handbook

Republic of the Philippines

UNIVERSITY OF EASTERN PHILIPPINES
University Town, Northern Samar

COLLEGE of NURSING and ALLIED HEALTH SCIENCES

DRUG ANALYSIS
 SPECIFIC CONTRAINDICA DRUG ADVERSE SPECIFIC NURSING
NAME OF DRUG INDICATION
ACTION TION INTERACTION REACTION PRECAUTION RESPONSIBILITIES
Generic Name: May inhibit Ketoralac is Allergy: Individuals DRUG-DRUG CNS: dizziness, Correct hypovolemia before Watch for and immediately
Ketoralac prostaglandine indicated for: who have a known headache, drowsiness, giving the drug evaluate signs and
synthesis to allergy to ketorolac Anticoagulas: May sedation symptoms of heart attack
produce anti- Acute pain or other NSAIDs increase anticoagulant Contraindicated for epidural
Brand Name: inflammatory, management: should not use this levels in blood CV: Arrythmias, edema, or intrathecal administration Carefully observe patients
Toradol Ketorolac is used
analgesic, and medication. HTN, palpitations due to its alcohol content with coagulopathies and
to manage acute
antipyretic effects Drug-herb such as those taking anticoagulants
pain, including
Route: abdominall pain Peptic ulcer disease horse chestnut, red EENT: increase NSAIDs may increase risk
Intravenous (IV) or bleeding clover: may cuase lacrimation, nasal of serious thrombotic Drug inhibit platelet
disorders: bleeding discomfort, rhinitis events, MI, stroke, which aggregation and can
Dose: Individuals with a can be fatal prolong bleeding time
30mg, history of peptic White willow: may GI: dyspepsia, GI pain,
ulcer disease or contain similar nausea, constipation Other specific precautions Patient Teaching:
bleeding disorders, components to involves pregnancy,
Frequency: such as hemophilia, ketorolac GU: Renal failure lactation, and reproduction Advise patient to maintain
30mg I.V PRN should not use which does not concern the adequate fluid intake
ketorolac due to an Drug lifestyle: alcohol: Hematologic: decrease client
increased risk of may increase risk of GI platelet adhesion Advise patient to be alert
Therapeutic Class: gastrointestinal bleeding for signs and symptoms of
NSAIDS bleeding. Skin: Diaphoresis, CV events
pruritus, rash
Active bleeding:
Tell patient to promptly
Reference: Individuals with
report edema and weight
Nursing 2021Drug active bleeding,
gain
Handbook such as those with a
recent history of a
Teach patient the warning
stroke or a history
signs and symptoms of
of gastric or
hepatoxicity and GI
intestinal bleeding
bleeding and to notify
should not use
prescribers immediately if
ketorolac.
any of these occurs.