Drug Name Action Indication Contraindication Adverse Effect Nursing

Consideration
Generic name: Inhibits cell-wall  Moderate to  Contraindicated in CNS: headache, insomnia, fever,  Before
piperacillin Na and synthesis during severe infection patients o seizures, agitation, dizziness, giving
tazobactam Na bacterial from pipericillin- hypersensitivity to anxiety. drugs ask
multiplication. resistant, drug or other the
Brand name: pepiricillin and penicillin CV: hypertension, tachycardia, patient
Zosyn *Route: I.V tazobactam –  Use cautiously in chest pain and edema about
Onset: immediate susceptible, beta- patients with allergic
Classification: Peak: immediate lactamase- bleeding EENT: rhinitis reactions
*extended Duration: unknown producing strains tendencies, uremia, to
spectrum penicillin, of microorganism hyperkalemia and GI: diarrhea, nausea, constipation, penicillin.
beta-lactamase in allergies to other pseudomembranous colitis,  Monitor
inhibitor. appendicitis(com drugs, especially vomiting, dyspepsia, stool hematolo
plicated by cephalosporins, changes, abdominal pain. gic and
Available forms: rupture or because of possible coagulati
Powder for abcess) cross-sensitivity. GU: interstitial nephritis, on
injection: 2g and peritonitis candidiasis paramete
piperacillin and caused by E.coli, rs.
tazobactam N; 3g Bacteroids Hematologic: leucopenia,
piperacillin and fragilis, neutropenia, thrombocytopenia, Patient Teaching:
0.375 tazobactam B.ovatus;skin to anemia, eosinophilia  Tell
Na per vial ; 4g skin-structure patient to
piperacillin and 0.5 infections caused Respiratory: dyspnea report
tazobactam per vial by S.aurelus; adverse
postpartumendo Skin: rash,pruritus reactions
metritis ore promptly.
pelvic Other: anaphylaxis, pain,  Tell
inflammatory inflammation phlebitis at I.V site, patient to
disease caused hypersensitivity reaction. alert a
by E.coli; health
moderately care
severe caused by professio
Haemophilus nal at the
influenzae . I.V site.