DRUG NAME INDICATIONS ACTIONS CONTRAINDICATIONS AND ADVERSE EFFECTS SIDE EFFECTS NURSING

CAUTIONS RESPONSIBILITIES

Generic Name: To treat infections Binds to bacterial Contraindications:  Antibiotic- Frequent: Before:
ceftriaxone of the lower cell membranes,  History of associated  Discomfort with  Consider right assessment,
respiratory tract, inhibits cell wall hypersensitivity/anaphylactic colitis IM administration right drug/medication, right
skin, soft tissue, synthesis. reaction to cephalosporins.  other  oral candidiasis patient and right dosage.
urinary tract, Therapeutic Hyperbilirubinemia superinfections (thrush)  obtain CBC, renal function
bones, and joints; Effect: neonates, esp. premature (abdominal  mild diarrhea tests. Question for history
Brand Name: sinusitis; Bactericidal. infants, should not be cramps, severe  mild abdominal of allergies, particularly
Rocephin intraabdominal treated with ceftriaxone (can watery diarrhea, cramping cephalosporins, penicillins.
infections; and displace bilirubin from its fever) may  vaginal
septicemia caused binding to serum albumin, result from candidiasis. During:
Drug class
Antibiotic
by anaerobes causing bilirubin altered bacterial Occasional:  Consider right approach,
(including encephalopathy). balance.  Nausea right route, right
Bacteroides bevies,  Do not administer with Nephrotoxicity  serum sickness- frequency/time, and right
Dosage, frequency Bacteroides fragilis, calcium-containing IV may occur, esp. like reaction principle of care.
------ Bacteroides solutions, including in pts with (fever, joint pain;  Assess oral cavity for white
melanogenic, and continuous calcium- preexisting renal usually occurs patches on mucous
Pepto containing infusion such as disease. after second membranes, tongue
streptococcus parenteral nutrition (in  Pts with history course of therapy (thrush).
species), gram- neonates) due to the risk of of penicillin and resolves after  Monitor daily pattern of
negative organisms precipitation of ceftriaxone- allergy are at drug is bowel activity, stool
(including calcium salt. increased risk discontinued). consistency.
Citrobacter species, Cautions: for developing a Rare:  Mild GI effects may be
Enterobacter  Hepatic impairment, severe  Allergic reaction tolerable (increasing
aerogenes,  history of GI disease (esp. hypersensitivity (rash, pruritus, severity may indicate onset
Escherichia coli, ulcerative colitis, reaction (severe urticaria), of antibiotic-associated
Haemophiles  antibiotic-associated colitis) pruritus  thrombophlebitis colitis).
influenzae,  Severe renal impairment angioedema, (pain, redness,  Monitor I&O, renal function
Klebsiella species,  history of penicillin allergy bronchospasm, swelling at tests for nephrotoxicity,
Neisseria species, anaphylaxis). injection site) CBC. Be alert for
Proteus mirabilis, superinfection: fever,
Proteus vulgaris, vomiting, diarrhea, anal/
Providencia species, genital pruritus, oral
Salmonella species, mucosal changes
Serratia (ulceration, pain,
marcescens, erythema).
Shigella, and some
strains of After:
Pseudomonas  Consider right education,
aeruginosa), and right evaluation, and right
gram-positive documentation.
organisms  Tell patient to immediately
(including report evidence of blood
Staphylococcus dyscrasia or superinfection
aureus, to prescriber.
Streptococcus  Urge patient to report
pneumoniae, and watery, bloody stools to
Streptococcus prescriber immediately,
pyogenes) even up to 2 months after
drug therapy has ended..