DRUG NAME DOSAGE MECHANISM INDICATION CONTRAINDICATION ADVERSE NURSING

OF ACTION EFFECT CONSIDERATIONS

Generic Availability: Hinders Indicated • Contraindicated in CNS: fever, pain, • Obtain hearing
Name: Capsules: 125 mg, bacterial cell- treatmeant for: patients hypersensitive to headache, fatigue.  evaluation before and
Vancomycin 250 mg  wall synthesis, Renal drug or its components.  during prolonged
Hydrochloride  Powder for damaging the insufficiency, CV: hypotension, therapy. 
(van-koh-MYE- injection: 500-mg bacterial plasma Serious or severe • Use cautiously in thrombophlebitis at
sin) vials, 750-mg vials, membrane and infections when patients receiving other injection site.  • Monitor patient's
1-g vials Powder making the cell other antibiotics neurotoxic, nephrotoxic, fluid balance and
Brand Name: for oral solution: more vulnerable are ineffective or or ototoxic drugs; in EENT: ototoxicity, watch for 
Cytovan 25 mg/mL, 50 to osmotic contraindicated, patients older than age tinnitus.  oliguria and cloudy
Forstaf mg/mL  pressure. Also including those 60; and in those with urine
Vanco – Cp Premixed for interferes with caused by impaired hepatic or renal GI: . 
Vancocin Cp injection: 500 RNA synthesis MRSA, function, hearing loss, or pseudomembranous • Monitor patient
Vancogen mg/100 mL, 750 Staphylococcus allergies to other colitis, nausea, carefully for red-man
Vancogram – mg/150 mL, 1 epidermidis, or antibiotics. abdominal pain, syndrome, which can
500 g/200 mL diphtheroid vomiting, diarrhea, occur if drug is infused
Vancorin organisms • It isn't known if drug flatulence.  too rapidly. Signs and
Vancotech Cp CDAD  CDAD causes fetal harm. Use symptoms include
Vanlid Adults: 125 mg PO during pregnancy only if GU: maculopapular rash on
Staphylococcal nephrotoxicity. 
Vanmycos – Cp every 6 hours for 10 enterocolitis clearly needed.  face, neck, trunk, and
Vansafe – Cp days. Children: 40 • Drug appears in human limbs and pruritus and
milk. Patient should Hematologic:
Vantox Cp mg/kg/day PO in leukopenia, hypotension caused by
three or four discontinue breastfeeding histamine release. If
Classification: divided doses for 7 or discontinue drug. neutropenia,
eosinophilia.  wheezing, urticaria, or
Anti- bacterial to 10 days. pain and muscle spasm
agent. Belongs Maximum daily Metabolic: of the chest and back
to dose is 2 g hypokalemia (PO).  occur, stop infusion
aminoglycoside Staphylococcal and notify prescriber. 
antibiotics enterocolitis
Adults: 500 mg to 2 Respiratory: • Don't give drug IM. 
g PO in three or dyspnea, wheezing.
Route: four divided doses Skin: red-man
PO syndrome (with • Assess renal function
daily for 7 to 10
IV rapid IV infusion). (BUN, creatinine level
days. Children: 40
Other: anaphylaxis, and CrCl, urinalysis,
mg/kg/day PO in
Forms: chills, and urine output)
three or four
Capsule before and during
divided doses for 7
Powder for oral therapy. 
to 10 days.
solution
Maximum daily • Carefully monitor
Powder for
dose is 2 g serum concentrations
Injection
Pharmacokinetics of vancomycin to
Absorption:   adjust IV dosage
GI tract: Poorly requirements. 
absorbed 
Systemic • Monitor patient for
absorption(60%) signs and symptoms of
Peak: superinfection. CDAD
IV: Immediate can occur up to 2
Distribution:  months after therapy
Distributed into ends.
milk
Metabolism: Not
metabolized in the
body
Elimination: Urine
and fecal
elimination
Half Life: 
4-6hr