1. The document discusses carboprost, a synthetic prostaglandin used to induce labor or expel the placenta in second trimester abortions between 13-20 weeks of gestation. It lists dosing and administration instructions, contraindications like hypersensitivity, and side effects to monitor like excessive vaginal bleeding and cramping.
2. Tranexamic acid is discussed for treating hereditary angioedema and heavy menstrual bleeding. It works by inhibiting fibrinolysis. Dosing instructions are provided for oral and intravenous administration in adults and pediatric patients. Adverse effects and drug interactions are noted.
3. Calcium salts are mentioned for oral use, but no further
1. The document discusses carboprost, a synthetic prostaglandin used to induce labor or expel the placenta in second trimester abortions between 13-20 weeks of gestation. It lists dosing and administration instructions, contraindications like hypersensitivity, and side effects to monitor like excessive vaginal bleeding and cramping.
2. Tranexamic acid is discussed for treating hereditary angioedema and heavy menstrual bleeding. It works by inhibiting fibrinolysis. Dosing instructions are provided for oral and intravenous administration in adults and pediatric patients. Adverse effects and drug interactions are noted.
3. Calcium salts are mentioned for oral use, but no further
1. The document discusses carboprost, a synthetic prostaglandin used to induce labor or expel the placenta in second trimester abortions between 13-20 weeks of gestation. It lists dosing and administration instructions, contraindications like hypersensitivity, and side effects to monitor like excessive vaginal bleeding and cramping.
2. Tranexamic acid is discussed for treating hereditary angioedema and heavy menstrual bleeding. It works by inhibiting fibrinolysis. Dosing instructions are provided for oral and intravenous administration in adults and pediatric patients. Adverse effects and drug interactions are noted.
3. Calcium salts are mentioned for oral use, but no further
SUBMITTED TO: JETH CABATAN DATE: JULY 2 2022 1.GENERIC •Abortion •Carboprost is a -HEMABATE •Hypersensitivity •Severe •Monitor NAME: Initial: 250 synthetic Sterile Solution •Acute pelvic pelvic pain, uterine Carboprost mcg IM; THEN prostaglandin. It is indicated for inflammatory disease cramping, or contractions trimethylamin repeat PRN binds the aborting •Active cardiac, vaginal and observe e q1.5-3.5hr OR prostaglandin pregnancy pulmonary, renal or bleeding; and report •An initial, E2 receptor, between the hepatic disease •High fever; excessive BRAND NAME: optional test causing 13th and 20th •A light- vaginal Hemabate dose of 100 myometrial weeks of headed bleeding and mcg IM; THEN contractions, gestation as feeling, like cramping CLASSIFICATIO increase dose casuing the calculated from you might pain. Save all N: to 500 mcg if induction of the first day of pass out; clots and Abortifacient response is labour or the the last normal •Shortness tissue for inadequate expulsion of the menstrual of breath physician with 250 mcg placenta. period and in •Severe inspection doses Prostaglandins the following nausea, and •No more occur naturally conditions vomiting, or laboratory than 1200 in the body and related to diarrhea; or analysis. mcg total act at several second •Increased •Check vital dose or 2 sites in the body trimester high blood signs at days of including the abortion: pressure regular continuous womb (uterus). • Failure of (severe intervals. administratio They act on the expulsion of the headache, Carboprost- n muscles of the fetus during the blurred induced •Refractory womb, causing course of vision, febrile Postpartum them to treatment by buzzing in reaction Uterine contract. another your ears, occurs in Bleeding method; anxiety, more than • Premature confusion, 10% of •Initial 250 rupture of chest pain). patients and mcg IM, membranes in must be repeat PRN intrauterine differentiated q15-90min methods with from loss of drug and endometritis, •No more insufficient or which occurs than 2000 absent uterine around third mcg or 8 activity; day after doses • Requirement abortion. of a repeat intrauterine instillation of drug for expulsion of the fetus; • Inadvertent or spontaneous rupture of membranes in the presence of a previable fetus and absence of adequate activity for expulsion. 2.GENERIC •For •Tranexamic •Taken orally, •Known allergy to TXA, •Adverse •Be alert for NAME: menstrual acid tranexamic acid intracranial bleeding, effects bleeding Tranexamic disorder in competitively is indicated for known defective color include gums, Acid adult: and reversibly the treatment of vision, history of venous or seizures, nosebleeds, Dose: 1300 inhibits the hereditary arterial thromboembolism, headaches, or other BRAND NAME: mg (two 650 activation of angioedema,6 or active thromboembolic backache, unusual Cyklokapron, mg tablets) plasminogen via cyclic heavy disease. Greater than 3 abdominal bleeding or Lysteda orally three binding at menstrual hours from traumatic pain, bruising that times a day several distinct bleeding in injury. nausea, might CLASSIFICATIO (3900 sites, including premenopausal vomiting, indicate N: mg/day) four or five low- females,5 and diarrhea, inadequate Bleeding; during affinity sites and other instances fatigue, drug effects. menstrual monthly one high-affinity of significant pulmonary Report signs disorder menstruation site, the latter of bleeding in the embolism, of bleeding Duration: which is context of deep vein to the Maximum of involved in its hyperfibrinolysis thrombosis, physician 5 days. binding to fibrin. .6 Given anaphylaxis, immediately. •Pediatric •The binding of intravenously, impaired •Assess Dose for plasminogen to tranexamic acid color vision, blood Bleeding: fibrin induces is indicated for and other pressure and Initial dose: fibrinolysis – by short-term use visual compare to 10 mg/kg occupying the (2-8 days) in disturbance normal intravenously, necessary patients with s. values. immediately binding sites hemophilia to Report low before dental tranexamic acid prevent or blood extraction prevents this reduce bleeding pressure Maintenance dissolution of following tooth (hypotension dose: 10 fibrin, thereby extraction. ), especially if mg/kg stabilizing the patient intravenously clot and develops three to four preventing dizziness or times daily hemorrhage. syncope Duration of therapy: 2 to 8 days 3.GENERIC •Injectable •Calcium is •Oral calcium •Hypersensitivity •Chalky •Assess for NAME: solution essential for the salts are used as •Intramuscular/subcutane taste cutaneous Calcium functional dietary ous (IM/SC) administration •Flatulence burning Gluconate •100mg/mL integrity of the supplemental •Ventricular fibrillation •Hypotensio sensations (10%) nervous, therapy for during CPR n and BRAND NAME: muscular, and person who may •High blood calcium •Tingling peripheral Kalsinate •Tablet skeletal not get enough sensation vasodilation, (hypercalcemia) systems. It plays calcium in their •Vomiting with CLASSIFICATIO •Digoxin poisonings 50mg a role in normal regular diet. •Slow or moderate fall N: •Sarcoidosis cardiac function, Calcium irregular in BP, during Calcium salt, 500mg renal function, gluconate is heartbeat direct IV Antidotes respiration, used as a injection. 650mg blood cardioprotective •Monitor for coagulation, and agent in high hypocalcemia Capsule (adult cell membrane blood and only) and capillary potassium. hypercalcemi permeability. Calcium a. 500mg •Also, calcium gluconate is the helps to antidote for regulate the magnesium release and sulfate toxicity. storage of neurotransmitte rs and hormones, the uptake and binding of amino acids, absorption of vitamin B 12, and gastrin secretion. 4.GENERIC •Adults And •Epinephrine •Epinephrine is •Narrow angle glaucoma •Severe •Monitor NAME: Children 30 kg acts on alpha one of the most •Shock stroke blood Epinephrine (66 lbs) Or and beta- commonly used •Brain damage •Pulmonary pressure, More adrenergic agents in •Coronary insufficiency edema heart rate BRAND NAME: receptors. various settings •Hypertension •Tachycardi and urine Adrenalin •0.3 to 0.5 Epinephrine acts as it functions as 2nd stage of labor a output. mg (0.3 to 0.5 on alpha and medication and •Oliguria •Report for CLASSIFICATIO mL) of beta receptors hormone. It is •Dyspnea tachycardia, N: undiluted and is the currently FDA- •Palpitation palpitations, Alpha/ Beta Adrenalin strongest alpha approved for s dizziness and agonist administered receptor various •Anxiety hypertension intramuscular activator.This situations, . ly or drug also including •Monitor IV subcutaneous produces an emergency site for ly in the increase in treatment of infiltration. anterolateral blood sugar and type 1 aspect of the increases hypersensitivity thigh, up to a glycogenolysis in reactions, maximum of the liver. including •Through its anaphylaxis, 0.5 mg (0.5 action on beta- induction, and mL) per adrenergic maintenance of injection, receptors, mydriasis during repeated epinephrine intraocular every 5 to 10 leads to surgeries and minutes as bronchial hypotension due necessary. smooth muscle to septic shock. relaxation that helps to relieve bronchospasm, wheezing, and dyspnea that may occur during anaphylaxis 5.GENERIC •Adults: Tab- •Hyoscine-N- •Buscopan •Myasthenia gravis •Dizziness •Raise side NAME: 10-20mg 3-5 butylbromide Tablets are narrow-angle glaucoma •Fatigue rails as a Hyoscine times daily. (HNBB) acts by indicated for the •Tachycardia •Drowsiness precaution Inj: 20mgs interfering with relief of spasm •Megacolon •Dry skin because BRAND NAME: several times the transmission of the genito- •Hypersensitivity •Painful some Buscopan daily as of nerve urinary tract or urination patients required. impulses by gastro- •Urinary become CLASSIFICATIO acetylcholine in intestinal tract retention temporarily N: •Children: the and for the •Eye excited or Antimuscarinic Tab- Over 6 parasympatheti symptomatic irritation disoriented , years, 10- c nervous relief of Irritable •Redness and some antispasmodic 20mg, 3-4 system. Bowel develop times daily. •Buscopan Syndrome. amnesia or Inj: Infants & exerts a become young spasmolytic drowsy. children: action on the •Drug 5mg. smooth muscle compatibility of the should be gastrointestinal, monitored biliary and closely in urinary tracts. patients requiring adjunctive therapy.