MIDWIFERY PHARMACOLOGIC NOTES

Generic Name: Oxytocin I.V.: 10-40 units Induction of labor at Nausea or vomiting, cardiac arrhythmias, > Monitor and record >Monitor BP during > Be alert for adverse
by I.V. infusion in term; control of memory problems or PVCs, hypertension, uterine contractions, heart administration reaction
1000 mL of postpartum bleeding; confusion, runny subarachnoid rate, BP, intrauterine
intravenous fluid adjunctive therapy in nose, sore throat, or hemorrhage pressure, fetal heart rate, >If contractions are less than 2 >Monitor I/O. Antidiuretic
Brand Name: Pitocin at a rate sufficient coughing, severe and blood loss q15. minutes apart, if they’re above effect may lead to fluid
management of
to control uterine headaches, Fetal effects: fetal 50mm Hg, or if they last overload, seizures, and coma
abortion
atony hallucinations, bradycardia, 90seconds or longer, stop
vomiting, confusion, neonatal jaundice, infusion, and turn patient on > Regulate rate of oxytocin
seizures and severe low Apgar scores >never give oxytocin her side, and notify prescriber delivery; monitor rate and
hypertension and simultaneously by more strength of contractions
Local Market Price:
irregular heartbeats. nauseas, vomiting, than one route.
postpartum >Ensure fetal position and
hemorrhage, uterine size and absence of
rupture, pelvic complications that are
hematoma, uterine contraindicated with
hypertonicity, spasm oxytocin therapy

DRUG CLASSIFICATION MECHANISM PREGNANCY EFFECT ON EFFECT ON > Ensure continuous

OF ACTION RISK CATEGORY PREGNANCY LACTATION observation for induction of
labor; fetal monitoring is
PC: Exogenous Agent TC: oxytocic, Causes potent and Oxytocin has been Oxytocin is It has been used in preferred.
lactation stimulant selective assigned to a indicated during mothers having
pregnancy category X pregnancy to induce difficulty with
stimulation of by the FDA. There are labor; it precipitates engorgement and
uterine and no known indications uterine contractions breast-feeding.
mammary gland for use in the first and abortion. Because several
smooth muscles, trimester of small studies have
pregnancy other than failed to show a
producing in relation to beneficial effect,
sustained spontaneous or oxytocin is not used
contractions, induced abortion. It for this indication.
induces labor and would not be Oxytocin is excreted
milk ejection and expected to present a in the breast-milk,
reduces risk of fetal but is not expected to
postpartum abnormalities. have adverse effects
bleeding in the infant.