Consultant Physician/Cardiologist and Senior Lecturer University of Nairobi Geographical distribution and transmission • Worldwide in distribution as a sexually transmitted infection common among sexually active people who have multiple partners and who don’t use condoms during intercourse • The parasite is a common cause of sexually transmitted disease in women, hence its name. Men usually remain asymptomatic. • The infection causes intense itching, foul smelling discharge (usually yellowish-green in colour and often described as rotten fish smell) • The parasite can also be transmitted during penetrative sex among homosexuals and during oral sex Morphology and life cycle • The parasite exists only in trophozoite form • It is a flagellated protozoa • Possesses an undulating membrane and an axostyle and a nucleus Life cycle • The parasite reproduces by binary division Treatment and control • The syndromic approach for management of STIs applies for genital discharges and the principle of ABCDE is commonly used • The DOC is Metronidazole, but Secnidazole, Tinidazole and other nitroimidazoles can be used • Control of the disease is like most STIs – abstinence, condom use, treatment of infected persons and contact tracing • Health education is very important about prevention Complications • Include pelvic inflammatory disease • Miscarriages • Ophthalmia neonatorum • Infantile STDs especially in female children sharing towels and underwear with infected adults • Genital excoriation and ulceration/laceration (traumatic)