The word "end" in this phrase has the same meaning as in the phrase "means to an end". The philosopher Immanuel Kant said that rational human beings should be treated as an end in themselves and not as a means to something else. The fact that we are human has value in itself. If a person is an end-in-themself it means their inherent value doesn't depend on anything else - it doesn't depend on whether the person is enjoying their life, or making other people's lives better. We exist, so we have value.
2. What is the significance of our actions in relation to
the ultimate end? We may not necessarily have an ultimate end, —though presumably we will change and evolve. Our actions will influence our direction of evolution; whether we succeed in preserving our planet, or in limiting war, and disease, and poverty.
3. How do our moral acts relate to the ultimate purpose of life?
All deliberate acts are moral acts, because it is your beliefs about right and wrong, which is your morality, that control you. It is by applying your moral beliefs to bestow meaning on your observations that you discover purpose for living.