Quiz 3

1. A farm worker was accidentally in the field during the aerial spraying with parathion. He
was brought to the emergency department. Which of the following will be used in the
treatment of this patient?
a. Antiseizure drugs
b. Atropine and pralidoxime
c. Hemodialysis
d. Hyperbaric oxygen
e. Measures to reduce pulmonary edema

2. An employee of a company engaged in clearing vegetation from county roadsides

accidentally ingested a small quantity of an herbicidal solution that contained paraquat.
Within2 h, he was admitted to the emergency department of a nearby hospital. Which of
the following best describes his probable signs and symptoms in the emergency
department?
a. Diarrhea, vomiting, sweating, and profound skeletal muscle weakness
b. Dizziness, nausea, agitation, and hyperreflexia
c. Dyspnea, pulmonary dysfunction, and elevated body temperature
d. Gastrointestinal irritation with hematemesis and bloody stools
e. Hypotension, tachycardia, and respiratory impairment

3. A small child is brought to a hospital emergency department suffering from severe

gastrointestinal distress and abdominal colic. If this patient has severe acute lead poisoning
with signs and symptoms of encephalopathy, treatment should be instituted immediately
with
a. Acetylcysteine
b. Deferoxamine
c. EDTA
d. Penicillamine
e. Succimer

4. Which of the following neurotransmitters undergoes synaptic enzymatic degradation

as the main mechanism by which its actions are terminated?
a. Serotonin
b. Dopamine
c. Norepinephrine
d. Glutamate
e. Acetylcholine

5. What agent reverses the neuromuscular junction acetylcholinesterase inhibition

caused by organic phosphorus agents?
a. Atropine
b. Diazepam
c. Glycopyrrolate
d. Pralidoxime
e. Lorazepam

6. What is the most common clinical finding in organic phosphorus poisoning that is
not effectively treated with atropine?
a. Bronchorrea
b. Miosis
c. Muscle weakness
d. Diarrhea
e. Bronchoconstriction

7. What is the most common clinical manifestation of the intermediate syndrome?

a. Proximal limp and cranial nerve weakness.
b. Mydriasis
c. Bronchorrhea
d. Ventricular dysrhythmias
e. Vomiting and diarrhea.

8. Which clinical manifestation of organic phosphorus agent poisoning is of greatest

life-threatening concern after acute exposure?
a. Bronchorrhea
b. Bradydysrhythmias
c. Respiratory insufficiency
d. Prolonged QTc interval
e. Increased GI motility

9. Which of the following statements about organic lead poisoning is correct?

a. It may result from sniffing leaded gasoline
b. Leaded gasoline contains tetraethyl lead
c. Symptoms can include irritability, nausea, vomiting and anxiety
d. Tremor, chorea and convulsions can occur following exposure to tetraethyl lead
e. All of the above.

10. Which of the following statements about lead is correct?

a. The major routes of entry into the body are the GI tract and the skin.
b. Lead is present in trace quantities in virtually every food and beverage
c. Adults absorb a greater percentage of ingested Lead than do children
d. Lead appears to concentrate in soft tissue
e. All of the above.
11. Substances that stimulate nicotinic cholinergic receptors (eg, organophosphates) may
initially cause tachycardia and hypertension, followed later by bradycardia and
hypotension.
a. True B. False

12. Hemodialysis would be most helpful for a medication overdose with which of
the following properties?
A. Large volume of distribution. High protein avidity.
B. Small volume of distribution. Low protein avidity.
C. Large volume of distribution. Low protein avidity.
D. Small volume of distribution. High protein avidity.

13. Alkalization of the urine by administration of sodium bicarbonate is likely to enhance

the elimination of xenobiotics with which of the following characteristics?
a. Amphoteric
b. Strongly acidic
c. Strongly alkaline+
d. Weakly acidic
e. Weakly alkaline

14. All of the following complications of forced diuresis are except:

a. Pulmonary congestion
b. Organism hyperhydratation
c. Brain congestion.
d. Acute renal failure.
e. Hypokalemia

15. Which of the following the most important to monitor when using atropine to treat a
patient with cholinergic poisoning?

A) Blood pressure
B) Pulse
C) Respiratory rate
D) Temperature
E) Mental status