Day 1

Latency to first entry to the hidden platform zone (s)

70

60

50

40

30

20

10

0
Saline Curcumin Vitamin A Yogurt Curcumin-Vitamin A Memantine
Fortified Yogurt

Treatment
Data plotted are means ± standard deviation

Figure 3. Latency to first entry to the hidden platform zone. The data analysed has been
limited in the following way: Treatment = Saline, Curcumin, Vitamin A, Yogurt, Curcumin-
Vitamin A Fortified Yogurt, Memantine or Undefined; Trial = Trial 1; Apparatus = MWM
and The reason for test end = New procedure or Test duration.

Latency to first entry to the hidden platform zone (s)

Treatment N Mean SD (note 1) Data (notes 2, 3, 4)
Saline 8 45.55 ±21.55 60.0 (1), 5.9 (2), 60.0 (3), 60.0
(4)
, 60.0 (5), 50.8 (6), 17.4 (7),
50.3 (8)
Curcumin 8 47.40 ±18.70 38.9 (9), 60.0 (10), 60.0 (11),
60.0 (12), 60.0 (13), 13.2 (14),
27.1 (15), 60.0 (16)
Vitamin A 8 31.76 ±26.17 10.4 (17), 60.0 (18), 60.0 (19),
42.1 (20), 9.4 (21), 60.0 (22), 9.3
(23)
, 2.9 (24)
Yogurt 8 32.69 ±23.87 12.2 (25), 60.0 (26), 9.5 (27),
25.5 (28), 3.5 (29), 60.0 (30),
57.9 (31), 32.9 (32)
Curcumin-Vitamin A Fortified Yogurt 8 31.31 ±19.04 60.0 (33), 60.0 (34), 13.6 (35),
25.5 (36), 22.5 (37), 33.9 (38),
11.2 (39), 23.8 (40)
Memantine 8 25.36 ±20.51 16.5 (41), 60.0 (42), 0.0 (43),
27.6 (44), 0.0 (45), 29.3 (46),
25.2 (47), 44.3 (48)

ANOVA (note 5) : F(5,42) = 1.2947 p = 0.2845

Notes:
1. SD = Standard deviation.
2. The data analysed has been limited in the following way: Treatment = Saline, Curcumin, Vitamin A, Yogurt,
Curcumin-Vitamin A Fortified Yogurt, Memantine or Undefined; Trial = Trial 1; Apparatus = MWM and The reason
for test end = New procedure or Test duration.
3. The numbers in parentheses next to the data values are animal numbers - you can click these to access the
animal's details report.
4. In cases where this event did not occur the system has used the test duration as the event's latency - you can alter
this behaviour using the options in the Protocol's Analysis element.
5. One-way ANOVA, fixed factor.
Day 4

Latency to first entry to the HIDDEN PLATFORM zone (s)

25

20

15

10

-5
SALINE CURCUMIN VITAMIN A YOGURT CURCUMIN-VITAMIN STD MEMANTINE
A YOGURT

Treatment
Data plotted are means ± standard deviation

Figure 2. Latency to first entry to the HIDDEN PLATFORM zone. The data analysed has
been limited in the following way: Treatment = SALINE, CURCUMIN, VITAMIN A,
YOGURT, CURCUMIN-VITAMIN A YOGURT or STD MEMANTINE ; Trial = Trial 1;
Apparatus = MWM and The reason for test end = ENTRY INTO HIDDEN PLATFORM or
Test duration.

Latency to first entry to the HIDDEN PLATFORM zone (s)

Treatment N Mean SD (note 1) Data (notes 2, 3)
SALINE 8 7.61 ±4.96 6.8 (1), 6.6 (2), 6.9 (3), 13.3 (4), 13.5
(5)
, 11.6 (6), 2.2 (7), 0.0 (8)
CURCUMIN 6 7.17 ±4.26 7.6 (9), 5.7 (10), 14.6 (11), 2.8 (12),
3.7 (14), 8.6 (15)
VITAMIN A 7 10.91 ±10.11 11.9 (17), 0.0 (18), 0.0 (19), 12.2 (21),
30.1 (22), 12.5 (23), 9.7 (24)
YOGURT 7 9.13 ±9.60 15.1 (25), 0.0 (26), 10.1 (27), 14.0 (28),
0.0 (29), #N/A (30), 24.7 (31), 0.0 (32)
CURCUMIN-VITAMIN A YOGURT 6 4.37 ±4.63 4.7 (33), 0.0 (35), 0.0 (36), 2.6 (37), 6.8
(38)
, 12.1 (39)
STD MEMANTINE 8 5.77 ±5.23 0.0 (41), 6.6 (42), 0.0 (43), 11.2 (44),
12.1 (45), 5.9 (46), 10.4 (47), 0.0 (48)

ANOVA (note 5) : F(5,36) = 0.7652 p = 0.5810

Notes:
1. SD = Standard deviation.
2. The data analysed has been limited in the following way: Treatment = SALINE, CURCUMIN, VITAMIN A, YOGURT,
CURCUMIN-VITAMIN A YOGURT or STD MEMANTINE ; Trial = Trial 1; Apparatus = MWM and The reason for test
end = ENTRY INTO HIDDEN PLATFORM or Test duration.
3. The numbers in parentheses next to the data values are animal numbers - you can click these to access the
animal's details report.
4. Data shown as #N/A represent a result that is undefined.
5. One-way ANOVA, fixed factor.
Day 5

Latency to first entry to the NW zone (s)

70

60

50

40

30

20

10

-10
SALINE CURCUMIN VITAMIN A YOGURT CURCUMIN-VITAMIN STD MEMANTINE
A YOGURT

Treatment
Data plotted are means ± standard deviation

Figure 3. Latency to first entry to the NW zone. The data analysed has been limited in the
following way: Treatment = SALINE, CURCUMIN, VITAMIN A , YOGURT, CURCUMIN-
VITAMIN A YOGURT or STD MEMANTINE; Trial = Trial 1; Apparatus = MWM and The
reason for test end = Test duration.
Number of entries to the NW zone
14

12

10

-2

-4
SALINE CURCUMIN VITAMIN A YOGURT CURCUMIN-VITAMIN STD MEMANTINE
A YOGURT

Treatment
Data plotted are means ± standard deviation

Figure 2. Number of entries to the NW zone. The data analysed has been limited in the
following way: Treatment = SALINE, CURCUMIN, VITAMIN A , YOGURT, CURCUMIN-
VITAMIN A YOGURT or STD MEMANTINE; Trial = Trial 1; Apparatus = MWM and The
reason for test end = Test duration.

Latency to first entry to the NW zone (s)

Treatment N Mean SD (note 1) Data (notes 2, 3, 4)
SALINE 8 25.74 ±28.67 6.0 (1), 0.0 (2), 0.0 (3), 60.0 (4), 6.7
(5)
, 13.2 (6), 60.0 (7), 60.0 (8)
CURCUMIN 8 34.19 ±25.19 19.6 (9), 60.0 (10), 0.0 (11), 47.5 (12),
14.2 (13), 12.2 (14), 60.0 (15), 60.0
(16)

VITAMIN A 8 23.80 ±30.00 1.3 (17), 3.8 (18), 0.0 (19), 60.0 (20),
60.0 (21), 60.0 (22), 1.9 (23), 3.4 (24)
YOGURT 8 40.29 ±27.33 10.5 (25), 60.0 (26), 60.0 (27), 60.0
(28)
, 60.0 (29), 10.0 (30), 60.0 (31), 1.8
(32)

CURCUMIN-VITAMIN A YOGURT 7 12.00 ±21.66 0.0 (33), 1.3 (34), 0.0 (35), 6.6 (36),
13.0 (38), 60.0 (39), 3.1 (40)
STD MEMANTINE 8 38.02 ±24.10 60.0 (41), 60.0 (42), 12.8 (43), 60.0
(44)
, 60.0 (45), 6.5 (46), 19.5 (47), 25.4
(48)

ANOVA (note 5) : F(5,41) = 1.2052 p = 0.3238

Notes:
1. SD = Standard deviation.
2. The data analysed has been limited in the following way: Treatment = SALINE, CURCUMIN, VITAMIN A , YOGURT,
CURCUMIN-VITAMIN A YOGURT or STD MEMANTINE; Trial = Trial 1; Apparatus = MWM and The reason for test
end = Test duration.
3. The numbers in parentheses next to the data values are animal numbers - you can click these to access the
animal's details report.
4. In cases where this event did not occur the system has used the test duration as the event's latency - you can alter
this behaviour using the options in the Protocol's Analysis element.
5. One-way ANOVA, fixed factor.
Day 2

Latency to first entry to the HIDDEN PLATFORM zone (s)

45

40

35

30

25

20

15

10

0
SALINE CURCUMIN VITAMIN A YOGURT CURCUMIN-VITAMIN STD MEMANTINE
A-YOGURT

Treatment
Data plotted are means ± standard deviation

Figure 2. Latency to first entry to the HIDDEN PLATFORM zone. The data analysed has
been limited in the following way: Treatment = SALINE, CURCUMIN, VITAMIN A ,
YOGURT, CURCUMIN-VITAMIN A-YOGURT or STD MEMANTINE.
Day 3

Test duration (s)

60

50

40

30

20

10

-10
SALINE CURCUMIN VITAMIN A YOGURT CURCUMIN-VITAMIN STD MEMANTINE
A YOGURT

Treatment
Data plotted are means ± standard deviation

Figure 1. Test duration. The data analysed has been limited in the following way:
Treatment = SALINE, CURCUMIN, VITAMIN A, YOGURT, CURCUMIN-VITAMIN A YOGURT
or STD MEMANTINE and The reason for test end = Entry into hidden platform.

Latency to first entry to the Hidden platform zone (s)

60

50

40

30

20

10

-10
SALINE CURCUMIN VITAMIN A YOGURT CURCUMIN-VITAMIN STD MEMANTINE
A YOGURT

Treatment
Data plotted are means ± standard deviation

Figure 2. Latency to first entry to the Hidden platform zone. The data analysed has been
limited in the following way: Treatment = SALINE, CURCUMIN, VITAMIN A, YOGURT,
CURCUMIN-VITAMIN A YOGURT or STD MEMANTINE and The reason for test end =
Entry into hidden platform.
0 FTS_TRACKPLOT 0 0 7500 7980;